CISE Affiliated Faculty Awarded $1.6M in Funding from NIGMS
ECE/SE Professor Yannis Paschalidis (CISE Co-Director) and BME Research Assistant Professor Dima Kozakov in collaboration with ME/SE Associate Professor Pirooz Vakili recently received a $1.6 million five-year R01 grant from the National Institute of General Medical Sciences (NIGMS, part of the NIH) in support of their research on “Refinement Methods for Protein Docking based on Exploring Multi-Dimensional Energy Funnels.”
The work will substantially improve upon computational methods for characterizing and predicting protein-protein interactions. It will enable treating relatively weak protein complexes involving larger proteins than what is possible today. This will result in a better understanding of processes such as metabolic control, immune response, signal transduction, and gene regulation.
More details on the project can be found on Prof. Paschalidis’ website.