Joseph Massaro, PhD

Professor, Biostatistics
Joseph Massaro
Crosstown Center – CT327


Joe Massaro is Assistant Professor of Biostatistics, Mathematics and Statistics. He currently teaches Applied Statistical Methods in Clinical Trials I and II in the Department of Biostatistics. He has won several teaching awards at the School of Public Health for these courses. Joe currently also serves as Managing Director of Biostatistics and Data Management at Harvard Clinical Research Institute, a contract research organization providing statistical and data management services for the device, pharmaceutical and biotechnology industries. Overall, he has over 15 years experience in the design and statistical analysis of clinical trials, and has co-authored several clinical trials-related articles. Joe also performs longitudinal statistical analysis for the Framingham Heart Study, assessing risk factors for cardiovascular disease and dementia. In addition, he assists in the oversight of data management at the Framingham Heart Study. He has been with the Department of Biostatistics and the Framingham Heart Study since 1998.

Other Positions:

  • Biostatistician, Framingham Heart Study
  • Boston Medical Center


  • Boston College, BA
  • Boston University, MA
  • Boston University, PhD

Classes Taught

  • SPHBS851
  • SPHBS861
  • SPHBS901


  • Published on 8/28/2014

    Alvey NJ, Pedley A, Rosenquist KJ, Massaro JM, O''Donnell CJ, Hoffmann U, Fox CS. Association of fat density with subclinical atherosclerosis. J Am Heart Assoc. 2014; 3(4).

    Read at: PubMed
  • Published on 8/1/2014

    Elmariah S, Furlan AJ, Reisman M, Burke D, Vardi M, Wimmer NJ, Ling S, Chen X, Kent DM, Massaro J, Mauri L. Predictors of Recurrent Events in Patients With Cryptogenic Stroke and Patent Foramen Ovale Within the CLOSURE I (Evaluation of the STARFlex Septal Closure System in Patients With a Stroke and/or Transient Ischemic Attack Due to Presumed Paradoxical Embolism Through a Patent Foramen Ovale) Trial. JACC Cardiovasc Interv. 2014 Aug; 7(8):913-20.

    Read at: PubMed
  • Published on 6/18/2014

    Pershad A, Fraij G, Massaro JM, David SW, Kleiman NS, Denktas AE, Wilson BH, Dixon SR, Ohman EM, Douglas PS, Moses JW, O''Neill WW. Comparison of the Use of Hemodynamic Support in Patients =80 Years Versus Patients <80 Years During High-Risk Percutaneous Coronary Interventions (from the Multicenter PROTECT II Randomized Study). Am J Cardiol. 2014 Sep 1; 114(5):657-64.

    Read at: PubMed
  • Published on 4/9/2014

    Xanthakis V, Sullivan LM, Vasan RS, Benjamin EJ, Massaro JM, D''Agostino RB, Pencina MJ. Assessing the incremental predictive performance of novel biomarkers over standard predictors. Stat Med. 2014 Jul 10; 33(15):2577-84.

    Read at: PubMed
  • Published on 3/4/2014

    Friedman DJ, Wang N, Meigs JB, Hoffmann U, Massaro JM, Fox CS, Magnani JW. Pericardial Fat is Associated With Atrial Conduction: The Framingham Heart Study. J Am Heart Assoc. 2014; 3(2):e000477.

    Read at: PubMed
  • Published on 3/1/2014

    Selker HP, Udelson JE, Massaro JM, Ruthazer R, D''Agostino RB, Griffith JL, Sheehan PR, Desvigne-Nickens P, Rosenberg Y, Tian X, Vickery EM, Atkins JM, Aufderheide TP, Sayah AJ, Pirrallo RG, Levy MK, Richards ME, Braude DA, Doyle DD, Frascone RJ, Kosiak DJ, Leaming JM, Van Gelder CM, Walter GP, Wayne MA, Woolard RH, Beshansky JR. One-Year Outcomes of Out-of-Hospital Administration of Intravenous Glucose, Insulin, and Potassium (GIK) in Patients With Suspected Acute Coronary Syndromes (from the IMMEDIATE [Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency Care] Trial). Am J Cardiol. 2014 May 15; 113(10):1599-605.

    Read at: PubMed
  • Published on 2/28/2014

    Rossignol P, Dobre D, Gregory D, Massaro J, Kiernan M, Konstam MA, Zannad F. Incident hyperkalemia may be an independent therapeutic target in low ejection fraction heart failure patients: Insights from the HEAAL study. Int J Cardiol. 2014 May 15; 173(3):380-7.

    Read at: PubMed
  • Published on 1/15/2014

    Dangas GD, Kini AS, Sharma SK, Henriques JP, Claessen BE, Dixon SR, Massaro JM, Palacios I, Popma JJ, Ohman M, Stone GW, O''Neill WW. Impact of hemodynamic support with Impella 2.5 versus intra-aortic balloon pump on prognostically important clinical outcomes in patients undergoing high-risk percutaneous coronary intervention (from the PROTECT II randomized trial). Am J Cardiol. 2014 Jan 15; 113(2):222-8.

    Read at: PubMed
  • Published on 12/14/2013

    Govindaraju DR, Pencina KM, Raj DS, Massaro JM, Carnes BA, D''Agostino RB. A systems analysis of age-related changes in some cardiac aging traits. Biogerontology. 2014 Apr; 15(2):139-52.

    Read at: PubMed
  • Published on 12/8/2013

    Murphy TP, Cooper CJ, Cutlip DE, Matsumoto A, Jamerson K, Rundback J, Rosenfield KA, Henrich W, Shapiro J, Massaro J, Yen CH, Burtch H, Thum C, Reid D, Dworkin L. Roll-in Experience from the Cardiovascular Outcomes with Renal Atherosclerotic Lesions (CORAL) Study. J Vasc Interv Radiol. 2014 Apr; 25(4):511-20.

    Read at: PubMed

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