Vaccines And Medications in Pregnancy Surveillance System (VAMPSS)

VAMPSS is a nationwide post-marketing surveillance system established to comprehensively monitor the use and safety of vaccines and medications during pregnancy. It represents a unique collaboration the American Academy of Asthma, Allergy & Immunology (AAAAI), the Organization of Teratology Information Specialists (OTIS), the Harvard Pregnancy Research Group, and the Birth Defects Study (BDS) / Pregnancy Health Interview Study (PHIS) at the Slone Epidemiology Center at Boston University.

The major goal of VAMPSS is to provide a badly-needed national post-marketing surveillance system that can evaluate the risks and safety of the wide range of vaccines and medicines used by pregnant women. VAMPSS is coordinated by the American Academy of Allergy, Asthma & Immunology (AAAAI) and includes investigators and data from OTIS and BDS as well as an Independent Advisory Committee composed of experts from various organizations (for example, the U.S. Centers for Disease Control and Prevention) who provide feedback and guidance to the team of scientific investigators.

Although VAMPSS activities are coordinated with relevant government agencies and professional organizations, VAMPSS is an independent surveillance system serving the public and private sector. None of the data involved in VAMPSS include personal identifiers, and the data remain under the complete control of each investigative team (e.g., BDS data are owned and controlled by investigators at the Slone Epidemiology Center of Boston University). VAMPSS has been supported by various government and private sources, depending on the specific medications and vaccines that are under study. The BDS component of VAMPSS was closed to data collection on 11/30/15, but the data accumulated over 39 years remains available for analyses.