Research Studies

Please follow the links below for complete information on each of our listed studies.  Studies are listed alphabetically.

Active Studies

Behavioral Surveillance of Acetaminophen Users: Knowledge, Attitudes, and Dosing Behavior
The behavioral surveillance program is designed to ascertain the characteristics of acetaminophen users, with a focus on those who exceed the maximum recommended daily dose.  The data will suggest areas for potential consumer interventions and allow for the monitoring of user attitudes, knowledge, and dosing behavior over time as interventions are undertaken.

Black Women’s Health Study (BWHS)
The BWHS is the largest follow-up study of the health of African-American women yet conducted. The purpose is to identify and evaluate causes and preventives of cancers and other serious illnesses in African-American women. (Follow the link to learn more and to see a list of special BWHS studies that are currently active.)

Centers for Excellence in Birth Defects Research and Prevention
The Slone Epidemiology Center is participating in the Massachusetts Center for Birth Defects Research and Prevention, one of eight such centers funded by the National Center on Birth Defects and Developmental Disabilities (CDC). These centers conduct surveillance and research aimed at the prevention of birth defects.

The Child and Adolescent Learning and Living Study (CALLS)
Hemifacial microsomia (HFM) is characterized by asymmetric underdevelopment of the face. Although HFM is the second most common craniofacial malformation, there have been few studies of its impact on affected children.

Epidemiology of Breast Cancer Subtypes in African-American Women
The purpose of this collaborative Program Project is to understand the etiology of specific subtypes of breast cancer in African American women, in particular, the basal-like subtype, which occurs about twice as often in African American women as in other ethnic groups and is associated with a worse prognosis than other subtypes.

Follow-up of DES Exposed Cohorts
The Slone Epidemiology Center is participating in a collaborative follow-up study of the long-term health effects of diethylstilbestrol (DES) exposure, with 4 other academic research centers and the National Cancer Institute.

Nested Case-Control Study of Maternal Herpes Viruses in Relation to Gastroschisis
This study will examine 4 infectious agents with patterns of occurrence that match the epidemiologic profile of gastroschisis: Epstein-Barr virus, herpes simplex virus 2, cytomegalovirus, and Chlamydia trachomatis, using data from the Finnish Maternity Cohort.

Pregnancy Health Interview Study (Birth Defects Study)
This ongoing study of factors in pregnancy that may be related to the health of newborns focuses on the safety and risks of a wide range of environmental exposures (primarily medications) in pregnancy.  (Follow the link to learn more and to see a list of special PHIS studies that are currently active.)

Pregnancy Study Online (PRESTO)
PRESTO is the first internet- based couples’ fertility study the United States. The PRESTO team along with their colleagues from Aarhus University in Denmark are utilizing online advertising techniques to recruit participants to study time-to-pregnancy (TTP). These studies look at how lifestyle factors such as diet, exercise, medication use, caffeine intake, etc. affect a couple’s chances of becoming pregnant. PRESTO is currently enrolling participants. If you or someone you know may be interested in joining, please direct them to our website: sites.bu.edu/presto.

Social Media and Risk-reduction Training for Infant Care Practices (SMART)
The purpose of this project is to address serious and ongoing challenges related to adherence to public health recommendations known to reduce the risk of Sudden Unexpected Infant Deaths.

The Study of Attitudes and Factors Affecting Infant Care Practices (SAFE)
The purpose of this project is to evaluate trends in infant sleep practices and the adoption of the American Academy of Pediatrics’ and the Public Health Service’s “Back to Sleep” recommendations to reduce the risk of Sudden Infant Death Syndrome (SIDS).


Completed Studies (M-R)

  • Multicenter Study (United States) of Agranulocytosis, Aplastic Anemia, and Thrombocytopenic Purpura
  • Multicenter Study of Gastroschisis and Small Intestinal Defects (SIA)
  • Multicenter Study of Persistent Gestational Trophoblastic Disease
  • Myocardial Infarction and Oral Contraceptive Use in Women under 50
  • Myocardial Infarction in Young Men in Relation to Vasectomy
  • National Analgesic Nephropathy Study (NANS)
  • Oxalobacter formigenes and Other Factors in Urolithiasis
  • Patient Registries at Slone: Myeloma and MDS
  • Pediatric Drug Surveillance (PeDS) Program
  • Pharmacogenetic Determinants of Human Birth Defects
  • Post-marketing Surveillance of Drugs Used to Treat Irritable Bowel Syndrome Using a Pharmacy-based Cohort (IBS)
  • Pre-pregnancy Obesity in Relation to Preterm Birth and Macrosomia
  • Psychosocial Outcomes in Early Elementary Aged Children with Craniofacial Malformations