Michael J. Corwin, M.D.

Michael CorwinSenior Epidemiologist
Slone Epidemiology Center

Associate Professor of Pediatrics and Epidemiology
Boston University Schools of Medicine and Public Health

mjcorwin@bu.edu

Education:

B.A., 1973, Northwestern University
M.D., 1977, Wayne State University School of Medicine

Resident: Pediatrics, 1977-1980,
SUNY Syracuse Health Sciences Center

Fellow: Neonatal/Perinatal Medicine, 1980-1982,
SUNY Syracuse Health Sciences Center

Research Interests:

Dr. Corwin’s research has been focused on the epidemiology and physiology of the sudden infant death syndrome.  He has been PI of the Collaborative Home Infant Monitoring Evaluation (CHIME), the National Infant Sleep Position (NISP) surveys, the Study of Attitudes and Factors Effecting Infant Care (SAFE), and Social Media and Risk-reduction Training for Infant Care Practices (SMART).  Dr. Corwin also has been Co-Director of the Massachusetts Center for SIDS, Medical Director of the MCHB Program to Enhance Performance of SIDS/OID Initiatives, and has participated in the SIDS Global Strategy Working group and NICHD 5-Year SIDS Research Plan Committee.  Dr. Corwin has also conducted a large number of industry-sponsored studies directed at FDA approval of pharmaceuticals and medical devices and serves as a principal at Care-Safe.

Publications

  • Goodin DS, Corwin MJ, Kaufman DW, Golub H, Reshef S, Rametta MJ, Knappertz V, Cutter G, Pleimes D. Causes of death among commercially insured multiple sclerosis patients in the United States. PLoS ONE (in press).
  • Shapiro-Mendoza CK, Colson ER, Willinger M, Rybin DV, Camperlengo L, Corwin MJ. Trends in infant bedding use: National Infant Sleep Position Study, 1993–2010. Pediatrics 2015;135(1):10-7. doi: 10.1542/peds.2014-1793.
  • McEvoy J, Millet RA, Dretchen K, Morris AA, Corwin MJ, Buckley P. Quantitative levels of aripiprazole parent drug and metabolites in urine. Psychopharmacology (Berl) 2014;231(23):4421-8. doi: 10.1007/s00213-014-3781-1.
  • Kaufman DW, Reshef S, Golub HL, Peucker M, Corwin MJ, Goodin DS, Knappertz V, Pleimes D, Cutter G. Survival in commercially insured multiple sclerosis patients and comparator subjects in the U.S. Mult Scler Relat Disord 2014;3:364-71. doi: 10.1016/j.msard.2013.12.003.
  • Rhein LM, Dobson NR, Darnall RA, Corwin MJ, Heeren TC, Poets CF, McEntire BL, Hunt CE, and The Caffeine Pilot Study Group. Effects of caffeine on intermittent hypoxia in infants born prematurely: a randomized clinical trial. JAMA Pediatr 2014;168(3):250-7. doi: doi:10.1001/jamapediatrics.2013.4371.
  • Vernacchio L, Corwin MJ, Vezina RM, Pelton SI, Feldman HA, Coyne-Beasley T, Mitchell AA. Xylitol syrup for the prevention of acute otitis media. Pediatrics 2014;133(2):289-95. doi: 10.1542/peds.2013-2373. PMCID: PMC3904279.
  • Colson ER, Willinger M, Rybin D, Heeren T, Smith LA, Lister G, Corwin MJ. Trends and factors associated with infant bed sharing, 1993-2010: the National Infant Sleep Position Study. JAMA Pediatr 2013;167(11):1032-7. doi: 10.1001/jamapediatrics.2013.2560. PMCID: PMC3903787.
  • Lister G, Rybin DV, Colton T, Heeren TC, Hunt CE, Colson ER, Willinger M, Corwin MJ, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group. Relationship between sleep position and risk of extreme cardiorespiratory events. J Pediatr 2012;161(1):22-5.e1. doi: 10.1016/j.jpeds.2012.01.035. PMCID: PMC3607104.
  • Corwin MJ. Apparent life threatening events. In: Rudolph CD, Rudolph AM, Lister G, First L, Gershon AA, eds. Rudolph’s Pediatrics. 22nd ed. New York: McGraw-Hill, 2011:451-4.
  • Hunt CE, Corwin MJ, Weese-Mayer DE, Davidson-Ward SL, Ramanathan R, Lister G, Tinsley LR, Heeren T, Rybin D, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group. Longitudinal assessment of hemoglobin oxygen saturation in preterm and full term infants in the first six months of life. J Pediatr 2011;159(3):377-83.e1. PMCID: PMC3479632.
  • Corwin MJ. Corwin MJ. Use of home cardiorespiratory monitors in infants. In: Basow D, ed. UpToDate. 2010. (Accessed at http://www.uptodateonline.com.)
  • Corwin MJ. Apparent life threatening event in infants. In: Basow D, ed. UpToDate. 2010. (Accessed at http://www.uptodateonline.com.)
  • Corwin MJ. Sudden infant death syndrome. In: Basow D, ed. UpToDate. 2010. (Accessed at http://www.uptodateonline.com.)
  • Smith LA, Colson ER, Rybin D, Margolis A, Colton T, Lister G, Corwin MJ. Maternal assessment of physician qualification to give advice on AAP-recommended infant sleep practices related to SIDS. Acad Pediatr 2010;10(6):383-8. doi: 10.1016/j.acap.2010.08.006. PMCID: PMC3209617.
  • Reichard DW, Atkinson AJ, Hong SP, Burback BL, Corwin MJ, Johnson JD. Human safety and pharmacokinetic study of intramuscular midazolam administered by autoinjector. J Clin Pharmacol 2010;50:1128-35. doi: 10.1177/0091270009358083.
  • Von Kohorn I, Corwin MJ, Rybin DV, Heeren TC, Lister G, Colson ER. Influence of prior advice and beliefs of mothers on infant sleep position. Arch Pediatr Adolesc Med 2010;164(4):363-9. PMCID: PMC2901910.
  • Colson ER, Rybin D, Smith LA, Colton T, Lister G, Corwin MJ. Trends and factors associated with infant sleep position: The National Infant Sleep Position Study, 1993 – 2007. Arch Pediatr Adolesc Med 2009;163(12):1122-8. PMCID: PMC2898125.
  • Fu LY, Colson ER, Corwin MJ, Moon RY. Infant sleep location: associated maternal and infant characteristics with SIDS prevention recommendations. Journal of Pediatrics 2008;153:503-8.
  • Hunt CE, Corwin MJ, Lister G, Weese-Mayer DE, Davidson-Ward S, Tinsely LR, Neuman MR, Willinger M, Ramanathan R, Rybin D, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group. Precursors of cardiorespiratory events in infants detected by home memory monitor.  Pediatric Pulmonology 2008;43:87-98.
  • Lewicke A, Sazonov E, Corwin M, Neuman M, Shuckers S, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group.  Sleep state classification from heart rate variability using computational intelligence: consideration of rejection in classification models. IEEE Transactions on Biomedical Engineering 2008;55:108-18.
  • Corwin HL, Gettinger A, Fabian TC, May A, Pearl RG, Heard S, An R, Bowers PJ, Burton P, Klausner M, Corwin MJ.  Efficacy and safety of erythropoietin in the critically ill. NEJM 2007;357:965-76.
  • Silver M, Corwin MJ, Bazan A, Gettinger A, Enny C, Corwin HL. Efficacy of recombinant human erythropoietin in critically ill patients admitted to a long term acute care facility:  a randomized double blind placebo controlled trial.  Critical Care Medicine 2006;2310-6.
  • Kinane T, Murphy J, Bass J, Corwin MJ. Comparison of respiratory physiology when infants are placed in car safety seats or car beds. Pediatrics 2006;118:522-7.
  • Colson ER, Levenson S, Rybine D, Calianos C, Margolis A, Colton T, Lister G, Corwin MJ. Barriers to following the supine sleep recommendations among mothers at four WIC Centers.  Pediatrics 2006;118:e243-50.
  • Hoppenbouers T, Hodgman JE, Rybine D, Fabrikant G, Corwin MJ, Crowell D, Weese-Mayer DE, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group. Sleep architecture in term and preterm infants beyond the neonatal period: the influence of gestational age (GA), steroids and ventilatory support. Sleep 2005;28:1428-36.
  • Colson ER, McCabe LK, Fox K, Levenson S, Colton T, Lister G, Corwin MJ. Barriers to following the back-to-sleep recommendations: insights from focus groups with inner city caregivers.  Ambulatory Pediatrics 2005;5:349-54.
  • Silvestri JM, Lister G, Corwin MJ, Smok-Pearsall SM, Baird TM, Crowell DH, Cantey-Kiser J, Hunt CE, Tinsely L, Palmer PH, Mendenhall RS, Hoppenbrouwers TT, Neuman MR, Weese-Mayer DE, Willinger M, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group. The Collaborative Home Infant Monitoring Evaluation:  factors influencing use of a home cardiorespiratory monitor for infants. Archives of Pediatrics & Adolescent Medicine 2005;159:18-24.
  • Hunt CE, Corwin MJ, Baird T, Tinsley LR, Palmer P, Rangasamy R, Crowell DH, Schafer S, Martin RJ, Hufford D, Peucker M, Weese-Mayer DE, Silvestri JM, Neuman MR, Cantey-Kiser J, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group. Cardiorespiratory events detected by home memory monitoring and one year neurodevelopmental outcome. Journal of Pediatrics 2004;145:465-71.
  • Bass J, Corwin MJ, Gozal D, Moore C, Nishida H, Parker S, Shonwald A, Wilker R, Stehle S, Kinane TB. Effect of chronic or intermittent hypoxia on cognition in childhood: a systematic review.  Pediatrics 2004;114:805-16.
  • Crowell DH, Brooks LJ, Corwin MJ, Davidson-Ward S, Hunt CE, Kapuniai LE, Neuman MR, Silvestri J, Tinsley L, Weese-Mayer DE, Di Fiore J, Peucker M, Grove JS, Pearce JW, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group. Ontogeny of arousal. J Clin Neurophysiol 2004;21:290-300.
  • Gottlieb DJ, Chase C, Vezina RM, Heeren TC, Corwin MJ, Auerbach SH, Weese-Mayer DE, Lesko SM. Sleep-disordered breathing symptoms are associated with poorer cognitive function in 5-year-old children. J Pediatr 2004;145:458-64.
  • McCoy RC, Hunt CE, Lesko SM, Vezina RM, Corwin MJ, Willinger M, Hoffman HJ, Mitchell AA. Frequency of bed sharing and its relationship to breastfeeding. J Dev Behav Pediatr 2004;25:141-9.
  • Vernacchio L, Lesko SM, Vezina RM, Corwin MJ, Hunt CE, Hoffman HJ, Willinger M, Mitchell AA.  Racial/ethnic disparities in the diagnosis of otitis media in infancy. Int J Pediatr Otorhinolaryngol 2004;68:795-804.
  • Gottlieb DJ, Vezina RM, Chase C, Lesko SM, Heeren TC, Weese-Mayer DE, Auerbach SH, Corwin MJ. Symptoms of sleep-disordered breathing in five-year-old children are associated with sleepiness and problem behaviors. Pediatrics 2003;112:870-7.
  • Hunt CE, Lesko SM, Vezina RM, McCoy R, Corwin MJ, Mandell F, Willinger M, Hoffman HJ, Mitchell AA.  Infant sleep position and associated health outcomes. Arch Pediatr Adolesc Med 2003;157:469-74.
  • Willinger M, Ko C-W, Hoffman HJ, Kessler RC, Corwin MJ. Trends in infant bed sharing in the United States, 1993-2000: The National Infant Sleep Position Study. Archives of Pediatrics & Adolescent Medicine 2003;157:43-9.
  • Vernacchio L, Corwin MJ, Lesko SM, Vezina RM, Hunt CE, Hoffman HJ, Willinger M, Mitchell AA. Sleep position of low birth weight infants. Pediatrics 2003;111:633-40.
  • Corwin MJ. Apparent life threatening events. In: Rudolph CD, Rudolph AM, Hostetter M, Lister G, Siegel N, eds. Rudolph’s pediatrics. 21st ed. McGraw-Hill: New York, 2003:352-5.
  • Corwin MJ, Lesko SM, Heeren T, Vezina RM, Hunt CE, Mandell F, McClain M, Mitchel AA. Secular changes in sleep position during infancy: 1995-1998. Pediatrics 2003;111:52-60.
  • Xu X, Schuckers SAC, Corwin MJ. Comparison of heart rate variability measurements in infants. Computers in Cardiol 2002;29:585-8.
  • Corwin HL, Gettinger A, Pearl RG, Fink MP, Levy MM, Shapiro MJ, Corwin MJ, Colton T. Efficacy of recombinant human erythropoietin in the critically ill patient: a randomized double-blind placebo controlled trial. JAMA 2002;288:2827-35.
  • Rosenberg L, Palmer JR, Wise LA, Horton NJ, Corwin MJ. Perceptions of racial discrimination and the risk of preterm birth. Epidemiology 2002;13:646-52.
  • Crowell DH, Kulp TD, Kapuniai LE, Hunt CE, Brooks LJ, Weese-Mayer DE, Silvestri J, Davidson-Ward S, Corwin MJ, Tinsley L, Peucker M, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group. Infant polysomnography: reliability and validity of infant arousal assessment. J Clin Neurophysiol 2002;19:469-83.
  • Neuman MR, Watson HL, Mendenhall RS, Zoldak JT, DiFiore JM, Peucker M, Baird TM, Crowell DH, Hoppenbrouwers TT, Hufford D, Hunt CE, Corwin  MJ, Tinsley LR, Weese-Mayer DE, Sackner MA, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group. Cardiopulmonary monitoring at home: the CHIME monitor. Physiological Measurement 2001;22:267-86.
  • Ramanathan R, Corwin MJ, Hunt CE, Lister G, Tinsley LR, Baird TM, Silvestri JM, Crowell DH, Hufford D, Martin RJ, Neuman MR, Weese-Mayer DE, Cupples LA, Peucker M, Willinger M, Keens TG, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group. Cardiorespiratory events recorded on home monitors: comparison of healthy infants with those at increased risk for SIDS. JAMA 2001;285:2199-207.
  • Rodriguez RM, Corwin HL, Gettinger A, Corwin MJ, Enny C, Gubler D, Pearl RG. Nutritional deficiencies and blunted erythropoietin response as causes of the anemia of critical illness.  Journal of Critical Care 2001;16:36-41.
  • Kulp TD, Corwin MJ, Brooks L Peucker M, Fabrikant G, Crowell DH, Hoppenbrouwers T, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group. The effect of smoothing on infant sleep and waking state architecture. Sleep 2000;23:893-9.
  • Weese-Mayer DE, Corwin MJ, Peucker MR, DiFiore JM, Hufford DR, Tinsley LR, Neuman MR, Martin RJ, Brooks LJ, Davidson Ward SL, Lister G, Willinger M, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group. Comparison of CHIME monitor identified apnea with end-tidal CO2 and thermistor. American Journal of Respiratory and Critical Care Medicine 2000;162:471-80.
  • Willinger M, Ko C-W, Hoffman HJ, Kessler RC, Corwin MJ. Factors influencing parents and other caregivers to change to non-prone sleeping position in the United States, 1994-1998: The National Infant Sleep Position Study. JAMA 2000;283:2135-42.
  • Corwin HL, Gettinger A, Rodriguez RM, Pearl RG, Gubler D, Enny C, Colton T, Corwin MJ. Efficacy of recombinant human erythropoietin in the critically ill patient: a randomized double-blind placebo controlled trial.  Critical Care Medicine 1999;27:2346-50.
  • Hunt CE, Corwin MJ, Lister G, Weese-Mayer DE, Neuman MR, Tinsley L, Baird TM, Keens TG, Cabral HJ, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group. Longitudinal assessment of hemoglobin oxygen saturation in healthy infants during the first six months of age.  Journal of Pediatrics 1999;135:580-6.
  • Lesko SM, Corwin MJ, Vezina RM, Mitchell AA, Hunt CE. Response to Dr. Moy concerning our paper “Changes in sleep position during infancy” [letter to the editor]. J Am Med Assoc 1999;281:984.
  • Corwin MJ, Lister GL, Silvestri J, Peucker M, Brooks L, Davidson-Ward SL, Hunt CE, Neuman MR, Crowell DH, Colton T, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group. Agreement between raters in the assessment of tracings of physiologic data recorded by a cardiorespiratory monitor used in the home.  Pediatric Research 1998;44:682-90.
  • Lesko SM, Corwin MJ, Vezina RM, Hunt CE, Mandell F, McClain M, Heeren T, Mitchell AA. Changes in sleep position during infancy: a prospective longitudinal assessment. J Am Med Assoc 1998;280:336-40.
  • Willinger M, Hoffman HJ, Wu K-T, Hou JR, Kessler RC, Ward SL, Keens T, Corwin MJ. Factors associated with non-prone sleeping position in the United States, 1992-1996: The National Infant Sleep Position Study.  JAMA 1998;280:329-35.
  • Brooks LJ, DiFiore JM, Martin RJ, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group.  Assessment of tidal volume over time in preterm infants using respiratory inductance plethysmography.  Pediatr Pulmonol 1997;23:429-33.
  • Crowell DH, Brooks L, Colton T, Corwin MJ, Hoppenbrouers T, Hunt CE, Kapuniai L, Lister G, Neuman MR, Peucker M, Davidson-Ward SL, Weese-Mayer DE, Willinger M, and the Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group.  Infant polysomnography: reliability. Sleep 1997;20:553-60.
  • Corwin MJ.  Infant sleep position and the sudden infant death syndrome.  Neonatal Respiratory Diseases 1997;7(1):1-7.
  • Corwin MJ, Lester BM, Golub HL. The infant cry: what can it tell us? Current Problems in Pediatrics 1996;26:325-34.
  • Corwin MJ, Mou SM, Sunderji SG, Gall S, How H, Patel V, Gray M.  Multicenter randomized clinical trial of home uterine activity monitoring: pregnancy outcomes for all randomized women.  American Journal of Obstetrics and Gynecology 1996;175:1281-5.
  • Bauchner H, Vinci R, Bak S, Pearson C, Corwin MJ.  Parents and procedures: a randomized controlled trial. Pediatrics 1996;98:861-7.
  • Wang X, Zuckerman B, Coffman GA, Corwin MJ.  Familial aggregation of low birthweight among white and black populations in the United States. New England Journal of Medicine 1995;333:1744-9.
  • Silvestri JM, Hufford DR, Durham J, Pearsall SM, Oess MA, Weese-Mayer DE, Hunt CE, Levenson SM, Corwin MJ. Assessment of compliance with home cardiorespiratory monitoring in infants at-risk for sudden infant death syndrome. J Pediatr 1995;127:384-8.
  • Corwin MJ, Golub HL.  Acoustic cry analysis and SIDS. In: Rognum TO, ed. Sudden infant death syndrome: new trends in the nineties. Scandinavian University Press: Oslo, 1995.
  • Corwin MJ, Lester BM, Sepkoski C, Peucker M, Kayne H, Golub HL. Newborn acoustical cry characteristics of infants subsequently dying of SIDS. Pediatrics 1995;96:73-7.
  • Corwin MJ, Lester, BM, Sepkoski, C, McLaughlin, S, Kayne H, Golub HL. Effects of in utero cocaine exposure on newborn acoustical cry characteristics.  Pediatrics 1992;89:1199-204.
  • Mou SM, Sunderji SG, Gall S, How H, Patel V, Gray M, Kayne H, Corwin MJ.  Multicenter prospective randomized clinical trial of home uterine activity monitoring for detection of preterm labor.  American Journal of Obstetrics and Gynecology 1991;165:858-66.
  • Lester BM, Corwin MJ, Sepkoski C, Seifer R, Peucker M, McLaughlin S, Golub HL.  Neurobehavioral syndromes in cocaine exposed newborn infants.  Child Development 1991;62:694-705.
  • Acker DB, Corwin MJ, Sachs BP, Shulman MA.  The non-stress test: transmission from the home. Journal of Reproductive Medicine 1989;34:971-4.
  • Lester BM, Corwin MJ, Golub HL.  Early detection of the infant at risk through cry analysis. In: Neuman JD, ed. The physiological control of mammalian vocalization. Springer: 1989.
  • Corwin MJ.  Life after the NICU.  Emergency Medicine 1986;18:49-57.
  • Corwin MJ, Weiner LB, Daniels DA.  Effect of oral antibiotics on the outcome of serous otitis media. International Journal of Pediatric Otorhinolaryngology 1986;11:109-12.
  • Golub HL, Corwin MJ.  A physioacoustic model of the infant cry. In: Lester BM, Boukydis CFZ, eds. Infant crying:  theoretical and research  perspectives. Plenum: New York, 1985: pp. 59-82.
  • Corwin MJ, Golub HL.  Medical applications of infant cry analysis. In: Milunsky A, Friedman E, Gluck A, eds. Advances in perinatal medicine. Plenum: New York, 1985: pp. 163-188.
  • Golub HL, Corwin MJ.  Infant cry:  a clue to diagnosis. Pediatrics 1982;69:197-201.