SickleGen Project (click here for more information)

  • SickleGen Database test example:  SickleGen database is a collection of phenotype and genotype data from different databases brought together to study sickle cell anemia.

Genome-Wide Association Studies

Genetic Modulation of Sickle Cell Anemia Phenotypesoutput

Genetic Modulation of Fetal Hemoglobin (HbF)

  • Article: Sebastiani et al., Bayesian Beta regression model used to discover new genetic modulators of HbF [ American Journal of Hematology]

Predicting Severity of Sickle Cell Disease

Gene Expression

    • HPAEC: Differential Gene Expression in Pulmonary Artery Endothelial Cells Exposed to Sickle Cell Plasma