NIEHS and other agencies within the federal system have a special interest in the possible reproductive and developmental effects of hazardous substances, including those caused by endocrine disrupting agents. Despite increasingly sophisticated work applied to the problem, there is still much to learn before we understand how serious the problem might be.
The Boston University Superfund Basic Research Program is composed of nine projects, organized into two blocks:
In epidemiological studies, the neurotoxic effects of low level prenatal and childhood exposure to perchloroethylene in drinking water are being studied in a community setting. In addition methods for detecting and analyzing patterns of spatial and toxicological data associated with developmental outcomes are being investigated.
In mechanistic studies, the program is exploring the underlying mechanics of xenobiotic/endocrine interactions and their effects to allow better understanding of the implications of perturbations of reproductive, developmental and immunological processes by hazardous substances in the environment.
| Recent Seminar On October 25th, 2006 Dr. Elaine Francis of the USEPA, presented a talk entitled "Career opportunities within the US Federal Government for scientists " This seminar began at 11:00 in the BRB 113. Sherilyn Sawyer and Dr. Gloria Callard hosted this seminar. For a full list of speakers, see the seminars link above. |
Recent Seminar On November 20th, 2006 Dr. Orla Conneely of Baylor College of Medicine, presented a talk entitled "NR4a Nuclear receptor transcription factors function as novel leukemic tumor suppressors " This seminar will begain at 12:00 in the LSEB basement auditorium, with refreshments served at 11:45. Sherilyn Sawyer and Dr. Gloria Callard are hosting this seminar. For a full list of speakers, see the seminars link above. |
| Recent Seminar On November 27th, 2006 Dr. Bruce Blumberg of the University of California, Irvine presented a talk entitled "Nuclear receptor signaling: from development to endocrine disruption and beyond" This seminar began at 12:00 in the LSEB basement auditorium, with refreshments served at 11:45. Dr. Ian Callard hosted this seminar. For a full list of speakers, see the seminars link above. |
Upcoming Meeting The Superfund Basic Research Program Annual Meeting will be held from December 10th-11th, 2006 in San Diego, California. For more information, see the SBRP main web page. |
| Upcoming Seminar On March 5th, 2007 Dr. Daniel Nebert of the University of Cincinnati Medical Center will be presenting a talk entitled "Oral benzo(a)pyrene, immunosuppression and tumors: role of the three CYP1 enzymes. This seminar will begin at 12:00 in the LSEB basement auditorium, with refreshments served at 11:45. Dr. David Waxman is hosting this seminar. For a full list of speakers, see the seminars link above. |
Recent Publication A symposium. "Genomics: Application to endocrine disruption in wild-life sciences and the human" organized by Ian and Gloria Callard, and a part of the 15th International Congress of Comparative Endocrinology (Boston, May 2005) was recently published in the Journal of Experimental Zoology (305A: 672-729) This symposium was supported by a supplemental grant to the BU-SBRP (ES 07381) from NIEHS. For more publications, see the publications link above. |