Kee Chan, PhD

Kee Chan, PhD

Title
Assistant Professor, Health Science
Program in Health Science
Director, Genomics & Decision Sciences Laboratory
Email
keechan@bu.edu
Phone
617-358-6025
Education
BS (molecular biology), University of California, San Diego
MS (biology), University of California, San Diego
PhD (epidemiology of microbial diseases), Yale University
Website or Lab
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CV
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Courses Taught

  • HS 320 Genomics in Public Health
    This course focuses on studying the impact of the genetics and genomics and their interactions with behavior, psychosocial factors, and environment on population health and disease in the post-Human Genome Project Era. Fundamental concepts of genetics, molecular biology, immunology, and epidemiology will be discussed. The effects of the advancement of high-throughput innovations in scientific discoveries in public health policies will be explored.
  • HS 470 Topics in Public Health
    This course addresses new and emerging issues in the field of public health through interactive case study method and the medical literature. The format is small group discussion. Topics vary each semester; but include infectious diseases (HIV/AIDS), maternal and child health (neonatal screening, vaccinations), chronic diseases (obesity, mental illness), health and human rights, and international health.

Scholarly and Research Interests

Public Health genomics, decision sciences, Markov modeling, cost-effectiveness analysis, genetic disorders, autism, health policy, interventions, genetic testing and screening

As a fellow in the Graduate Partnerships Program at National Institutes of Health (NIH), Kee Chan conducted her research at the National Human Genome Research Institute while completing her PhD in epidemiology of microbial diseases from Yale University School of Public Health. Her specific aims were to develop a newborn screening test for severe combined immunodeficiency, understand T cell diversity during gestation and the neonatal period and evaluate the costs and benefits of newborn screening. She received both her Bachelor of Science in Molecular Biology and Master of Science in Biology from the University of California, San Diego.

Currently, at Boston University, her research program focuses on using decision-making sciences tools in evaluating different screening and intervention strategies in improving population health. Studying public attitudes and awareness toward innovative technologies for the development of screening for genetic disorders, chronic diseases, and developmental disorders can assist scientists and policymakers in assessing critical public health issues both to the community affected with the condition and to the general public. One project is evaluating the cost-effectiveness of screening for children with autism and the impact of screening on health services provided by the Massachusetts Department of Public Health. Another project is examining the dissemination of genetic testing and genomic information in social networks. Dr. Chan has a secondary appointment at the School of Public Health at Boston University.

Selected Publications

Kee Chan and Jennifer M. Puck. “Development of Population-based Newborn Screening for Severe Combined Immunodeficiency” Journal of Allergy and Clinical Immunology, Feb 2005, 115: 391-8.

Xiaoyan Ying, Kee Chan, Priti Shenoy, Myriam Hill and Nancy H. Ruddle. “Lymphotoxin Plays a Crucial Role in the Development and Function of Nasal-Associated Lymphoid Tissue through Regulation of Chemokines and Peripheral Node Addressin” American Journal of Pathology. 2005,166:135-146.

Danielle Drayton, Kee Chan, Warner Lesslauer, Jason Lee, Xiaoyan Ying, and Nancy H Ruddle. “Lymphocyte Traffic in Lymphoid Organ Neogenesis: Differential Roles of LTa and LTab” Advance Experimental Medicine and Biology, 2002, 512:43-8.

Kee Chan, Delphine J. Lee, Amy Schubert, Chih Min Tang, Brian Crain, Stephen P. Schoenberger, and Maripat Corr. “The Roles of MHC class II, CD40, and B7 Costimulation in CTL induction by plasmid DNA” Journal of Immunology, 2001, 166:3061-3066.

Selected Presentations

Chan K, PhD (February 2009), “To Screen or Not to Screen? Decision-Making in Population-based Genetic Testing and Screening”, 32nd Annual Bioethics Conference, Boston College, Boston, MA.

Chan, K, PhD (November 2008), “To Screen or Not to Screen? A Cost-Effectiveness Analysis of Screening for Pediatric Disorders”, Department of Health Policy and Management, Boston University, Boston, MA.

Chan, K, PhD (November 2008), “What’s Behind Screening?”, Department of Epidemiology, Boston University, Boston, MA.

Chan K, PhD (November 2008) “To Screen or Not to Screen? An Evaluation Model to Assess the Costs, Health Benefits, and Societal Factors Involved in Screening for Children with Autism”, (poster), Keck Future Initiatives Conference on Complexity, Irvine, CA.

Lin S, and Chan K, PhD (July 2008) ” Examination of Cost and Effectiveness of Interventions for Children with Autism Spectrum Disorders”. Boston University School of Public Health Practicum Poster Session, Boston, MA.

Lee Y, and Chan K, PhD (July 2008) “Health Policy Framework: Cost and Benefits of Screening for Children with Autism Spectrum Disorders” Boston University School of Public Health Practicum Poster Session, Boston, MA.

Chan, K, PhD, (April 2008) “Research Intensive Careers in Academia and Government” at First NIH Career Symposium, Bethesda, MD.

Chan, K, PhD, (April 2008) “Past, Present, and Future of Newborn Screening”. Presented at Brown Bag Seminar at Boston University, Boston, MA.

Chan K, (June 2007) “T cell Receptor Excision Circles: Application to Newborn Screening and the Understanding of Human T cell diversity.” Presented at National Human Genome Research Institute Seminar Series, Bethesda, MD.

Chan K (April 2007), National Human Genome Research Institute DNA Ambassador, “Celebrate the Genome: Double Helix to Health.” Presented at Edison High School Biology Class, Alexandria, VA, April 2007.

Professional Activities

  • Co-Chair, Maternal and Child Health Section on Improving Pregnancy Outcomes (IPO), American Public Health Association (APHA)
  • Member, Genome Science Institute, Boston, MA
  • Member, APHA Genomic Forum
  • Advisor, Premedical and Predental Advisory Board Committee, Boston University
  • Member, Association of Women in Sciences (AWIS)
  • Reviewer, Human Subjects Use Institutional Review Board (IRB) Committee, Boston University
  • Member, Women in Science and Engineering (WISE), Boston University

Awards and Honors

  • Invitation to the Attend the National Academies Keck Future Initiative Meeting, 2008
  • Genetic Alliance Transformational Leadership Scholarship, 2008
  • Invitation to Attend 57th Annual Nobel Laureates Meeting in Lindau, Germany, 2007
  • Fourth Annual NIH-Graduate Student Research Symposium Poster Award, 2007
  • L’Oreal USA Women in Science Fellowship, Honorary Mention, 2004
  • National Human Genome Research Institute (NHGRI) Retreat Poster Award, 2003
  • Federation of Clinical Immunology Societies Travel Award, 2003
  • National Institutes of Health (NIH) Research Training Fellowship, 2002