Claus-Christian Hilgetag, PhD

Claus-Christian Hilgetag, PhD

Adjunct Associate Professor, Department of Health Sciences, Boston University
Programs in Human Physiology
Associate Professor of Neuroscience, School of Engineering and Science, Jacobs University, Bremen, Germany
PhD (Computational neuroscience) University of Newcastle upon Tyne, UK
Graduate studies (Computational neuroscience) Oxford University, UK
BS, MS (Biophysics) Humboldt University Berlin, Germany
Undergraduate studies (Neuroscience) Edinburgh University, UK

Research Focus

We attempt to understand the global organization of structural and functional connectivity of the mammalian cerebral cortex using multivariate and computational analyses of databases of qualitative as well as quantitative connection data. In addition, we use computational modeling in order to explore the relationship between structural and functional brain connectivity.

These theoretical investigations are complemented by experimental studies to identify the functional contributions of different brain regions, using ‘virtual lesion’ approaches based on cooling deactivation or transcranial magnetic stimulation (TMS). The experimental studies particularly focus on the organization and function of human brain networks for attention.

Selected Publications

  • Kaiser M, Hilgetag CC: Nonoptimal component placement, but short processing paths, due to long-distance projections in neural systems, PLoS Computational Biology 2 (2006) e95.
  • Hilgetag CC, Barbas H: Role of mechanical factors in the morphology of the primate cerebral cortex, PLoS Computational Biology 2 (2006) e22 (cover article).
  • Sporns O, Chialvo D, Kaiser M, Hilgetag CC: Organization, development and function of complex brain networks, Trends in Cognitive Sciences 8 (2004) 418-425 (cover article). [79 citations]
  • Hilgetag CC: Learning from switched-off brains, Scientific American Mind 14 (2004) 8-9.
  • Hilgetag CC, Théoret H, Pascual-Leone A: Enhanced visual spatial attention ipsilateral to rTMS-induced ‘virtual lesions’ of human parietal cortex, Nature Neuroscience 4 (2001) 953-957. [140 citations]
  • Hilgetag CC, Burns GAPC, O’Neill MA, Scannell JW, Young MP: Anatomical connectivity defines the organisation of clusters of cortical areas in macaque monkey and cat, Phil Trans R Soc Lond B 355 (2000) 91-110. [70 citations]
  • Hilgetag CC, O’Neill MA, Young MP: Indeterminate organization of the visual system, Science 271 (1996) 776-777. [62 citations]