Curriculum

For students who plan to major in the natural sciences or environmental science, and for premedical students. Required for biology majors. No prerequisite. High school biology is assumed. The evolution and diversity of life; principles of ecology; behavioral biology. Three hours lecture, three hours lab including several field studies. Carries natural science divisional credit (with lab) in CAS. Effective Fall 2018, this course fulfills a single unit in each of the following BU Hub areas: Scientific Inquiry I, Quantitative Reasoning I, Critical Thinking, Research and Information Literacy. (Credits: 4)

For science majors and minors who require a two-semester general chemistry course, but have little prior experience with chemistry. Topics include: atoms and molecules; quantum theory and atomic structure, chemical periodicity; bonding in diatomic and polyatomic molecules; stoichiometry and introduction to reactions in aqueous solutions; properties of gases; and thermochemistry and the first law of thermodynamics.Laboratory exercises include basic training in lab safety and handling of chemical and experiments complementing the lectures, such as investigations of the size of an atom, gas laws, thermochemistry, and quantum aspects. Students must register for the following four (4) course components: lecture, discussion, pre-lab lecture, and laboratory. Carries natural science divisional credit (with lab) in CAS. Effective Fall 2018, this course fulfills a single unit in each of the following BU Hub areas: Scientific Inquiry I, Quantitative Reasoning I. (Credits: 4)

Basic introduction to field of psychology; topics include theories and findings governing learning, memory, perception, development, personality, social and abnormal psychology. Three hours large lecture and one hour discussion section or three hours of small lecture class with no discussion sections. Students are required to participate as subjects in psychology studies. 4 cr. either sem. Effective Fall 2018, this course fulfills a single unit in each of the following BU Hub areas: Social Inquiry I, Critical Thinking. Effective Fall 2019, this course will fulfill a single unit in each of the following BU Hub areas: Social Inquiry I, Critical Thinking, Ethical Reasoning. (Credits: 4)

This course is designed to facilitate successful integration into Sargent College for first-year students. Resources and guidelines will be made available to aid first-year students in making informed academic decisions while clarifying and enhancing the students' experiences with the Boston University community. Interaction with faculty and student leaders is provided. (Credits: 0)

For students planning to major in the natural sciences and for premedical students. Required for biology majors. It is strongly recommended students complete CAS CH 101 (or equivalent) before this course. High school biology is assumed. Biochemistry, cell & molecular biology, Mendelian & molecular genetics, physiology, and neurobiology. Three hours lecture, three hours lab. Carries natural science divisional credit (with lab) in CAS. Effective Fall 2018, this course fulfills a single unit in each of the following BU Hub areas: Scientific Inquiry II, Quantitative Reasoning II, Critical Thinking, Teamwork/Collaboration. (Credits: 4)

Undergraduate Prerequisites: CAS CH 101. Second semester general chemistry for students who have completed CAS CH101. Topics include: properties of solids and liquids; colligative properties; chemical kinetics; equilibrium; acids, bases, and buffers; solubility and precipitation; electrochemistry; and spontaneity, free energy, and the second law of thermodynamics. Laboratory exercises include experiments complementing the lectures, such as investigations of the freezing point of solutions, kinetics, acid-base titrations, and electrochemistry. Students must have completed CAS CH 101 prior to enrolling in CAS CH 102. Students must register for the following four (4) course components: lecture, discussion, pre-lab lecture, and laboratory. Carriers natural science divisional credit (with lab) in CAS. Effective Fall 2018, this course fulfills a single unit in each of the following BU Hub areas: Scientific Inquiry I, Quantitative Reasoning I. (Credits: 4)

Through readings, discussion and written work, we explore the functions of the health and rehabilitation disciplines. An introduction to the health care system and social impact of health and disability is also considered especially with respect to allocation of resources to improve outcomes. Effective Fall 2018, this course fulfills a single unit in the following BU Hub area: Oral and/or Signed Communication. (Credits: 2)

Principles of cellular organization and function: biological molecules, flow of genetic information, membranes and subcellular organelles, and cell regulation. Three hours lecture, one hour discussion. Students may receive credit for CAS BI 203 or 213, but not both courses. Effective Fall 2019, this course fulfills a single unit in each of the following BU Hub areas: Scientific Inquiry I, Quantitative Reasoning I, Critical Thinking. (Credits: 4)

Fundamentals of contemporary organic chemistry, including skeletal and electronic structure, stereochemistry, and reactions of important functional groups. Applications of organic reactions to important synthetic targets in materials and drug discovery will be highlighted, as will reactions pertinent to biochemistry. Laboratory includes training in basic organic chemistry skills, such as extraction, reaction performance, spectroscopy interpretation and chromatography. Effective Fall 2018, this course fulfills a single unit in each of the following BU Hub areas: Scientific Inquiry I, Quantitative Reasoning I. (Credits: 4)

Students may receive credit for not more than one of the following courses: CAS MA 121 or CAS MA 123. Differentiation and integration of functions of one variable. Same topics as CAS MA 123, but with less emphasis on mathematical generality and more on applications. Especially suitable for students concentrating in the biological and social sciences. Carries MCS Divisional credit in CAS. Effective Fall 2018, this course fulfills a single unit in the following BU Hub area: Quantitative Reasoning II. Effective Fall 2020, this course fulfills a single unit in each of the following BU Hub areas: Quantitative Reasoning II, Social Inquiry II, Critical Thinking. (Credits: 4)

An introduction to physiological principles applied across all levels of organization (cell, tissue, organ system). Preparation for more advanced courses in physiology. Topics include homeostasis and neural, muscle, respiratory, cardiovascular, renal, endocrine, gastrointestinal, and metabolic physiology. Three hours lecture, three hours lab. Effective Fall 2019, this course fulfills a single unit in each of the following BU Hub areas: Scientific Inquiry II, Writing-Intensive Course, Critical Thinking, Teamwork/Collaboration. (Credits: 4)

Lecture and discussion shared with CAS CH 204. Three hours lecture, one hour discussion weekly, one hour prelab lecture, four hours lab. Effective Fall 2019, this course fulfills a single unit in the following BU Hub areas: Scientific Inquiry II, Quantitative Reasoning I, Research and Information Literacy. (Credits: 4)

Students may receive credit for not more than one of the following courses: CAS MA 122, MA 124, or MA 129. Continuation of CAS MA 121. Review of univariate calculus, calculus of the elementary transcendental functions, elementary differential equations, elementary multivariate calculus. Applications to exponential growth, optimization, equilibrium, and dynamic modeling problems. Carries MCS divisional credit in CAS. Effective Fall 2018, this course fulfills a single unit in the following BU Hub area: Quantitative Reasoning II. Effective Fall 2020, this course fulfills a single unit in each of the following BU Hub areas: Quantitative Reasoning II, Social Inquiry II, Critical Thinking. (Credits: 4)

Introductory biochemistry. Protein structure and folding, enzyme mechanisms, kinetics, and allostery; nucleic acid structure; macromolecular biosynthesis with emphasis on specificity and fidelity; lipids and membrane structure; vitamins and coenzymes; introduction to intermediary metabolism. Three hours lecture, one hour discussion, four hours lab. Effective Fall 2020, this course fulfills a single unit in each of the following BU Hub areas: Writing- Intensive Course, Quantitative Reasoning II, Critical Thinking, Teamwork/Collaboration. Effective Spring 2024, this course fulfills a single unit in each of the following BU Hub areas: Quantitative Reasoning II, Critical Thinking, Teamwork/Collaboration. (Credits: 4)

The CAS PY 105/106 sequence satisfies premedical requirements. PY105 covers some of the basic principles underlying the physics of everyday life, including forces and motion, momentum and energy, harmonic motion, rotation, and heat and thermodynamics. Carries natural science divisional credit (with lab) in CAS. Effective Fall 2018, this course fulfills a single unit in each of the following BU Hub areas: Scientific Inquiry I, Quantitative Reasoning I, Critical Thinking. (Credits: 4)

This course provides an introduction in the scientific foundations of nutrition and focuses on the relationship between diet and health. Scientific information is presented in preparation for discussion of macro- and micro nutrients and their role in human health and disease. (Credits: 4)

Undergraduate Prerequisites: First Year Writing Seminar (e.g., WR 100 or WR 120), (CASBI421 OR CASCH421) or equivalent. - Cell metabolism, with special emphasis on the uptake of food materials, the integration and regulation of catabolic, anabolic, and anaplerotic routes, and the generation and utilization of energy. Lectures include consideration of events in prokaryotic and eukaryotic organisms. Three hours lecture, one hour discussion, four hours lab. Effective Spring 2024, this course fulfills a single unit in each of the following BU Hub areas: Writing-Intensive Course, Research and Information Literacy, Teamwork/Collaboration, Creativity/Innovation. (Credits: 4)

The CAS PY 105/106 sequence satisfies premedical requirements. PY106 covers some of the basic principles underlying the physics of everyday life, including electricity and magnetism, direct-current circuits, waves, optics, and modern physics. Carries natural science divisional credit (with lab) in CAS. Effective Fall 2018, this course fulfills a single unit in each of the following BU Hub areas: Scientific Inquiry II, Quantitative Reasoning II, Critical Thinking. (Credits: 4)

Lecture and laboratory related to the detailed study of development, morphology, internal configuration, and functions, and pathological deficits of the peripheral and central nervous system in humans. Spring semester only. (Credits: 4)

How do humans breathe? How harmful are e-cigarettes to our body? What are the differences between an obstructive vs. a restrictive pulmonary disease? In Pulmonary Pathophysiology we will discuss these questions and more, developing an understanding of the physiological mechanisms underlying the function of the pulmonary system in health and disease. Through group discussion, active learning activities, and the creation of short films in small groups, we will take an in-depth look into the current understanding of pulmonary pathophysiology. Effective Spring 2021, this course fulfills a single unit in each of the following BU Hub areas: Digital/Multimedia Expression, Creativity/Innovation. (Credits: 4)

For MS students conducting research projects, including thesis work, under faculty guidance. (Credits: Var)

This course provides an overview of biostatistical methods, and gives students the skills to perform, present, and interpret basic statistical analyses. Topics include the collection, classification, and presentation of descriptive data; the rationale of estimation and hypothesis testing; analysis of variance; analysis of contingency tables; correlation and regression analysis; multiple regression, logistic regression, and the statistical control of confounding; sample size and power considerations; survival analysis. Special attention is directed to the ability to recognize and interpret statistical procedures in articles from the current literature. Students will use the R statistical package to analyze public health related data. * Can't be taken together for credit with SPH PH 717 (Credits: 3)

Synthesis, structure, function, regulation of macromolecules (DNA, RNA, protein). Prokaryotic and eukaryotic molecular biology. Topics include: replication, repair, recombination, transcription, translation, 5-methylcytosine, transcription factors, DNA looping (enhancer- promoter, insulator, etc.), histone modification/chromatin remodeling, non-coding RNA. Discussion of genetic and recombinant DNA techniques, including CRISPR/Cas9. (Credits: 4)

This course will cover the skills beyond benchwork that are necessary to be a competitive physiologist. The classes will be a mix of didactic information and group discussion. Methodological issues covered will include study design, techniques used, interpretation of research findings and the process of peer reviewed publication. Practical experience in grant writing and scientific seminar presentation will be included. Students completing this course will understand the principles underlying preparation and publication of scientific manuscripts, grants and seminars and will be able to apply these principles as they read the scientific literature and participate in research projects related to thesis work. (Credits: 2)

For MS students conducting research projects, including thesis work, under faculty guidance. (Credits: Var)

This course focuses on eukaryotic gene regulation. Course topics include genome organization and DNA rearrangement, RNA interference and noncoding RNAs, gene editing, mouse transgenic approaches, signal transduction pathways, chromatin structure, and cell cycle. Research articles will be discussed. (Credits: 4)

For MS students conducting research projects, including thesis work, under faculty guidance. (Credits: Var)

Animals receive a constant stream of sensory input that they use to adjust their behavior. In this course we explore how sensory systems translate the physical features of the outside world into meaningful patterns of neural activity. (Credits: 4)

The process of drug discovery is complex especially when a drug is intended to treat a neurological disease. This discussion-heavy course examines the specific challenges of modern neuroscience drug discovery, including: target selection, pharmacodynamics, animal models, and clinical trials. Effective Fall 2021, this course fulfills a single unit in each of the following BU Hub areas: Digital/Multimedia Expression, Scientific Inquiry II, Creativity/Innovation. (Credits: 4)

Examines critical components of systems biology, including design principles of biological systems (e.g., feedback, synergy, cooperativity), and the generation and analysis of large-scale datasets (e.g., protein- protein interaction, mRNA expression). (Credits: 4)

Cellular and molecular basis of neural excitability and synaptic transmission. The molecular understanding of ion channels is extrapolated to higher brain functions such as learning, memory, and sleep. Three hours lecture, three hours laboratory, one hour pre-lab. (Credits: 4)

Topics include electrical properties of neurons, a survey of neurotransmitters, molecular structure and function of receptors, synaptic transmission, intracellular signaling, and the molecular biology of sensory transduction. Three hours lecture, one hour discussion. Also offered as CAS NE 481. Effective Spring 2021, this course fulfills a single unit in each of the following BU Hub areas: Oral and/or Signed Communication, Scientific Inquiry II, Research and Information Literacy. (Credits: 4)

Current understanding of essential topics and important problems in modern cell biology, with emphasis on recent experimental findings, research strategies and approaches, and new techniques for investigating how cells work. Three hours lecture, one hour discussion. (Credits: 4)

In-depth analysis of current topics in molecular biology regarding the flow of information in the nucleus of eukaryotic cells. Focus on primary literature. Includes genomic flexibility, signal transduction to the nucleus, chromatin structure, gene expression, cell cycle checkpoints, health-related topics. (Credits: 4)

Advanced survey course in neurobiology. Topics covered include cell biology of the neuron, neurophysiology, neuropharmacology, cell signaling, anatomical methods, development of the nervous system, and human neuroanatomy. Three hours lecture, one hour discussion. (Credits: 4)

Exploration of mechanisms of signal transduction, communication, and integration in the nervous system. The approach is multidisciplinary, drawing upon fundamental concepts of the neuroanatomy, neurochemistry, and physiology of the nervous system. Lectures focus on patterns of processing in unimodal sensory, polymodal, motor, and limbic cortices. Methods used to investigate the nervous system are described and illustrated to facilitate comprehension of the current literature. (Credits: 4)

Practical experience in a research laboratory, clinic, community or individual setting as appropriate. (Credits: Var)

Investigation-based independent course examining the visceral anatomy of two cadavers. The course begins with instruction in dissection techniques, then full dissection of two cadavers is performed. Based on the findings, students determine the cause of death of one of the cadaveric individuals and write a case report. Grading: 85% case report, 15% participation. (Credits: Var)

Review of basic principles of neuroscience at an intermediate level, followed by readings and discussion on topics from the current neurosciences research. 4 credits, 2nd semester every other year (Credits: 4)