Biological Agent Information Sheets

The Office of Research Compliance (ORC) has identified a list of biological agents approved for use within the Boston University/Boston Medical Center research community that have the potential to cause laboratory acquired infection (LAI). While LAI is a rare event, the research community continues to take proactive measures to further mitigate risk to researchers, safety personnel and medical providers.

ROHP has worked together with the Office of Research Safety to prepare individual information sheets focused on laboratory safety for each of the biological agents with the potential to cause laboratory acquired infection (LAI). The sheets contain agent specific information on safety and handling precautions, transmission and symptoms, medical contact information and immediate steps to take in the event of an exposure.

These agent specific sheets will be reviewed with and issued to each PI and researcher as part of ROHP’s medical clearance process in support of the IBC’s protocol review and approval involving these biological agents.

BSL-4 Agents



BSL-3 Agents

Francisella tularensis

Mycobacterium tuberculosis

Yersenia pestis

BSL-2+/BSL-3 Agent

Human Immunodeficiency Virus

BSL-2 Agents

Acanthamoeba Castellani

Ascaris Suum

Brazilian vaccinia

Burkholderia cepacia

Chlamydia trachomatis

Clostridium difficile

Cowpox brighton

E. coli 0157:H7

Haemophilus influenzae

Herpes B Virus Non-human Primates

KPC klebsiella

La Crosse encephalitis virus (LACV, LAC)

Measles Virus

Methicillin-resistant Staphylococcus aureus

Mumps Virus

Mycobacterium bovis/BCG

Neisseria gonorrhea

Neisseria meningitidis

Newcastle disease

Plasmodium falciparum

Polio Virus

Rabies Virus

Salmonella typhimurium

Streptococcus pyogenes

Vaccinia virus

Vancomycin Resistant Enterococcus

Vibrio cholera pacini O1 biovar eltor str. N16961

Yersenia enterocolitica

Zika virus