Drs. Finnerty & Gilmore's research featured in MCB journal

02/10/2011

Research led by Biology PhD student Francis Wolenski is featured on the cover of the March, 2011 issue of the journal, Molecular and Cellular Biology. This paper is the product of an ongoing NSF-funded collaborative project between the labs of Drs. John Finnerty and Tom Gilmore. In this paper, the authors describe for the first time the molecular components of the NF-kB signaling pathway in a simple marine organism, the sea anemone Nematostella vectensis. These results have interesting evolutionary implications, as the NF-kB pathway is important in humans for proper immune responses and is misregulated in many cancers. Also contributing to the paper were postdoctoral fellow Michael Garbati, PhD students Tristan Lubinski, Nikki Traylor-Knowles, Derek Stefanik and undergraduates Erica Dresselhaus and Haley Goucher. In addition to NSF, funding for this project came from NIH, Conservation International, the Warren-McLeod Fellowship Program, New England Biolabs and the BU Undergraduate Research Opportunities Program (UROP).
 

MCB cover

MCB cover