Featured Technologies
Lab-on-a-chip
BU and Fraunhofer USA are collaborating to develop a lab-on-a-chip diagnostic platform based on work from Prof. Catherine Klapperich’s lab.
Point-of-care: brings results to the patient with a turn around time (TAT) of one (1) hour, significantly reducing the TATs associated with current detections methods (e.g. cultures, immunoassays, PCR,) resulting in faster diagnoses and informed drug therapies.
Reduced cost: the technology has been developed with low-cost low manufacturing methods in mind such as the use of injection molding, and reducing the number of assembly steps. In addition, as a fully integrated system, this technology requires less skilled labor, uses less reagents, and does not require any specialized facilities.
Resources: To be posted
Stem Cells from Adult Cells
The STEMCCA vector creates induced pluripotent stem cells from adult cells. It is a powerful in vitro tool for cellular reprogramming and has been successfully employed in mouse and human cell models.
The STEMCCA vector also has Cre/lox technology for removal of the viral genome, which is a critical step towards clinical application.
Resources: To be posted
New Angiogenesis Target
School of Medicine researchers discovered a new angiogenesis target, DEspR, which plays a critical role in developmental and tumor biology.
The DEspR homozygous knockout mouse is embryonic lethal due in part to a lack of blood vessels in the placenta, yolk sac and embryo, highlighting the importance of this receptor in developmental angiogenesis. The inventors have further demonstrated that administering antibodies to DEspR substantially reduces tumor growth, since tumors are also angiogenesis-dependent.
Resources: To be posted
Contrast Agent
A novel contrast agent that can monitor cartilage content in the knee developed by chemistry Prof. Mark Grinstaff.
A cationic CT contrast agent that enables diagnosis of early stage osteoarthritis (OA) as well as measures treatment response by visualizing cartilage degradation.
Resources: To be posted
HiLo Microscopy
Prof. Jerome Mertz has developed HiLo technology that enables existing wide-field light microscopes to render images that are equivalent to confocal microscopy at a fraction of the cost.
This technology enables existing wide-field light microscopes to render images that are equivalent to confocal microscopy at a fraction of the cost. The technology can be embodied in either a backward compatible retrofit for the exiting install base or incorporated into new instruments.
Resources: To be posted
Treatment of Osteoarthritis
An inflatable soft knee brace for the treatment of osteoarthritis (OA) with the performance of a rigid brace that is light weight, easy to use and easy to manufacture.
Resources: To be posted