OSP FO# 11-214

AGENCY: National Science Foundation (NSF)/Directorate for Mathematical & Physical Sciences (MPS)/Division of Mathematical Sciences (DMS)/National Institutes of Health (NIH)/National Institute of General Medical Sciences (NIGMS)

PROGRAM: Joint DMS/NIGMS Initiative to Support Research at the Interface of the Biological and Mathematical Sciences (DMS/NIGMS)

OBJECTIVES: This program supports research in the mathematical sciences with biological applications. Appropriate application areas are those currently supported by the National Institute of General Medical Sciences (NIGMS). A direct relationship between a biological application and mathematics is expected. Research teams that include scientists from both the life sciences community and the mathematical sciences community are encouraged. Both new and existing collaborations will be supported. Proposals from individual investigators will need to make the case that the individual has expertise in both areas. Successful proposals will either identify innovative mathematics or statistics needed to solve an important biological problem or involve the formulation and analysis of new mathematical models whose analysis poses significant mathematical challenges.

Examples of areas of research that are appropriate under this competition include the following:
·         Evolutionary, ecological and population dynamics;
·         Differentiation and developmental processes;
·         Explanatory and predictive models of cellular behavior;
·         Molecular and cellular networks;
·         New approaches to the prediction of molecular structure;
·         Simulations of the human systemic responses to burn, trauma and other injury;
·         New approaches to understanding system-wide effects of pharmacological agents and anesthetics, and their genetic and environmental modifiers.

These areas of research are examples only. They are not meant to be inclusive. Mathematical scientists, both pure and applied, and others capable of developing the mathematical and statistical tools envisioned are encouraged to apply. The work that is supported under this initiative must impact biology and advance mathematics or statistics.

Please see the program announcement below for further program details.

DEADLINE: October 3, 2011

FUNDING INFORMATION: NSF anticipates providing $5 million to support 15 to 20 standard or continuing grants. The NSF will support $2 million of the yearly program budget, and $3 million will be supported by NIGMS. Award sizes are expected to range from $100,000 to $400,000 per year (total costs) with durations of 3-5 years. Estimated program budget, number of awards and average award size/duration are subject to the availability of funds.

Upon conclusion of the review process, meritorious applications may be recommended for funding by either NIGMS or NSF, at the option of the agencies. Subsequent grant administration procedures will be in accordance with the individual policies of the awarding agency.

Mary Ann Horn, Program Director
National Science Foundation
4201 Wilson Boulevard
Arlington, Virginia 22230
Telephone: (703) 292-4879
Email: mhorn@nsf.gov
Web: http://www.nsf.gov/pubs/2010/nsf10579/nsf10579.htm

REMARKS: Applications must be submitted electronically using either the NSF FastLane system or Grants.gov. Collaborative proposals must be submitted via FastLane. For more information about FastLane, or to register as a FastLane user, please contact India Adams (adamsi@bu.edu) or A. B. Effgen (abeffgen@bu.edu) in the Office of Sponsored Programs (OSP) at x3-4365. Information about Grants.gov for BU Investigators can be obtained on the OSP web site at: http://www.bu.edu/osp/proposal-preparation/electronic-submission/. In addition, for investigators interested in submitting proposals via Grants.gov, NSF has published the NSF Grants.gov Application Guide which may be found online at: http://www.nsf.gov/bfa/dias/policy/docs/grantsgovguide.pdf. Investigators should contact the OSP Assistant Director assigned to their school or department as soon as possible to coordinate submission through either FastLane or Grants.gov.

Three changes have been made that impact the format of the proposal and deviate from GPG or NSF Grants.gov Application Guide guidelines.

1)  Project Description: The project description should consist of two distinct parts. (1) No more than 12 pages addressing the NSF criterion of Intellectual Merit. Note that this NSF criterion corresponds with the NIH criteria of Significance, Investigators, Innovation, Approach, and Environment. (2) Up to 3 additional pages addressing the NSF criterion of Broader Impacts.

2)  Biographical Sketches: Biographical Sketches are limited to three pages each (in contrast to the two page limit in the GPG) and are required for all senior personnel. In addition to the information required by the GPG, each Biographical Sketch must include a paragraph describing that person’s role in the project. In particular, the additional page permitted in each biographical sketch may be used to include information addressing the Multiple PD/PI Leadership Plan, an NIH requirement.

3)  Protection of Human Subjects/Use and Care of Vertebrate Animals: Both NSF and NIH have rules regarding the use of human subjects and/or vertebrate animals in research. Proposals that involve human subjects or use vertebrate animals must include the information required by both agencies. See the NSF Grant Proposal Guide (Proposal Preparation, Special Guidelines) and the NIH PHS Form 398 for additional information. Information on the use of human subjects and/or vertebrate animals is considered in the review of the proposals and should be submitted separately as a Supplementary Document.

Complete program guidelines and application material (NSF 10-579 and NSF GPG 11-1) may be obtained from the web site listed above or from the Office of Sponsored Programs (OSP). Please distribute this notice to any faculty or staff members who might be interested in the information. For more information, please contact the OSP at X3-4365 or ospinfo@bu.edu, or visit the OSP web site at http://www.bu.edu/osp.