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OSP FO# 11-107

AGENCY: Department of Health and Human Services (DHHS)/National Institutes of Health (NIH)/National Cancer Institute (NCI)/National Heart, Lung, and Blood Institute (NHLBI)/National Human Genome Research Institute (NHGRI)/National Institute on Aging (NIA)/National Institute on Alcohol Abuse and Alcoholism (NIAAA)/National Institute of Allergy and Infectious Diseases (NIAID)/National Institute of Biomedical Imaging and Bioengineering (NIBIB)/Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)/National Institute on Deafness and Other Communication Disorders (NIDCD)/National Institute on Drug Abuse (NIDA)/National Institute of Environmental Health Sciences (NIEHS)/National Institute of General Medical Sciences (NIGMS)/National Institute of Mental Health (NIMH)/National Institute of Neurological Disorders and Stroke (NINDS)/National Institute of Nursing Research (NINR)/National Center for Complementary and Alternative Medicine (NCCAM)/Office of Behavioral and Social Sciences Research (OBSSR)/National Institute on Dental and Craniofacial Research (NIDCR)/Fogarty International Center (FIC)

PROGRAM: Research on Ethical Issues in Biomedical, Social and Behavioral Research (R01, R03, R21)

OBJECTIVES: This program provides funding for investigator-initiated research to study high priority bioethical challenges and issues associated with the types of biomedical, social, and behavioral research supported by the participating NIH Institutes/Centers. The results of projects funded under this program announcement should enhance the ethical conduct and social value of research within the NIH mission, optimize the protection of human research participants, ensure research burdens and benefits are equitably distributed across populations, and contribute to policy development regarding the implementation and oversight of new research discoveries and methods.

Applications should address bioethical challenges and ethical issues relevant to the research mission area(s) of the participating NIH Institutes and Centers (ICs). The participating ICs have identified specific bioethics topics as the highest priority for consideration, organized into seven categories: 1) ethical considerations of new and emerging technologies; 2) research study design issues; 3) issues associated with therapeutic misconception and the interface between treatment and research; 4) research involving vulnerable populations and urgent situations; 5) research with existing specimens, data, and health information; 6) dissemination and translation of research findings; and 7) oversight of research.

For specific bioethics topics from the participating ICs, and a description of the IC research mission areas, please consult the program announcements below. Applications that address other bioethical issues directly related to these mission areas will also be considered. Interdisciplinary and collaborative projects utilizing multiple approaches are strongly encouraged.

The R01 grant mechanism solicits empirical, hypothesis-driven, confirmatory research and modeling approaches. The R03 grant mechanism is intended to support pilot and feasibility studies; small, self-contained research projects; development of research methodology; and development of new research technology that can be carried out in a short period of time with limited resources. The R21 grant mechanism encourages exploratory, descriptive or hypothesis-generating research, breaking new ground or extending previous discoveries toward new directions or applications.

R01: February 5, June 5, and October 5, until May 8, 2014
R03, R21: February 16, June 16, and October 16, until May 8, 2014

FUNDING INFORMATION: These programs will utilize the NIH Research Project Grant (R01), the NIH Small Research Grant (R03), and the NIH Exploratory/Developmental (R21) award mechanisms, and “Just-in-Time” information concepts. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. For the R01 program, budgets are not limited, but need to reflect actual needs of the proposed project. The scope of the proposed projects should determine the project period. The maximum period is 5 years.

For the R03 program, budgets for direct costs of up to $50,000 per year, and a project duration of up to two years may be requested, for a maximum of $100,000 over two years.

For the R21 program, the total project period may not exceed two years and direct costs are limited to $275,000 over a two-year period, with no more than $200,000 in direct costs allowed in any single year.

Ann Hardy
Office of Extramural Programs, OER
Office of the Director
National Institutes of Health
RKL1 – One Rockledge Center, 3002
6705 Rockledge Dr
Bethesda, MD 20817
Telephone: (301) 435-2690
Email: hardyan@od.nih.gov
Web: R01: http://grants.nih.gov/grants/guide/pa-files/PA-11-180.html
R03: http://grants.nih.gov/grants/guide/pa-files/PA-11-181.html
R21: http://grants.nih.gov/grants/guide/pa-files/PA-11-182.html

REMARKS: NIH requires that applications to this program be submitted electronically through Grants.gov (http://www.grants.gov). After submission via Grants.gov, applications will be retrieved and processed by the NIH Commons system (https://commons.era.nih.gov/commons/index.jsp). In order to prepare a responsive application, PIs should download both the complete program guidelines (R01: PA-11-180, R03: PA-11-181, R21: PA-11-182) and the corresponding application package from Grants.gov as well as the NIH Grants.gov Application Guide (http://grants.nih.gov/grants/funding/424/index.htm). PIs must also be registered Commons users.

For more information about Grants.gov and the NIH Commons, or to register as a Commons user, please contact either India Adams (adamsi@bu.edu) or A. B. Effgen (abeffgen@bu.edu) in the Office of Sponsored Programs (OSP) at x3-4365. In addition, please contact the OSP Assistant Director assigned to your school or department as soon as possible to coordinate submission through the Grants.gov system.

Complete program guidelines and application material may be obtained from the web site listed above or from the Office of Sponsored Programs (OSP). Please distribute this notice to any faculty or staff members who might be interested in the information. For more information, please contact the OSP at X3-4365 or ospinfo@bu.edu, or visit the OSP web site at http://www.bu.edu/osp.