OSP FO# 11-038

AGENCY: Department of Health and Human Services (DHHS)/National Institutes of Health (NIH)/Department of Biotechnology (DBT), Republic of India/National Institute of Neurological Disorders and Stroke (NINDS)/National Institute on Drug Abuse (NIDA)/National Institute of Mental Health (NIMH)

PROGRAM: U.S.-India Bilateral Brain Research Collaborative Partnerships (U.S.-India BRCP) (R21)

OBJECTIVES: This program provides funding to support the establishment and enhancement of bilateral research collaborations between U.S. and Indian investigators in the field of neuroscience with an emphasis on understanding, treating and curing neurological, mental and addictive disorders. Specific areas of research may include, but are not limited to, studies of mechanisms underlying neurological, mental and addictive disorders and diseases, planning for population-based research and clinical trials, development of infrastructure for resource, tool and data sharing in addition to projects aimed at advancing global health research, particularly as it relates to the mission of the participating organizations.

The collaboration/partnership must involve a U.S. investigator (PD/PI) from an eligible U.S. institution and at least one Indian investigator (PD/PI) who is affiliated with an eligible Indian institution (as determined by the DBT). Applications supported by this program must involve integrated research projects that are enhanced by the inclusion of both U.S. and India components. Successful applications will include a well-presented justification for the bilateral collaboration, and detailed experimental approaches that will be completed by each component. Research applications should be submitted as a single application by the U.S. Institution to the NIH.

A critical feature of this program is the establishment of Brain Research Collaborative Partnerships (BRCPs) among investigators and institutions in the U.S. and India. Applications may be derived from existing formal or informal collaborations with a history of interaction, or from new partnerships developed in response to this program. The BRCP must be based on a closely interactive partnership that maximizes the expertise of the research partners from both countries. Research areas may include, but are not be limited to:

-    studies of mechanisms underlying neurological, mental and addictive disorders and diseases;
-    translational research, including the development of biomarkers, therapeutics and devices;
-    development of public repositories (e.g., genetic repositories);
-    development of infrastructures for resource, tool and data sharing.

For more research areas, and examples of research approaches, please consult the program announcement below. Applicants are strongly encouraged to consult with NIH Program Staff as plans for an application are being developed. This early contact will provide an opportunity to clarify the applicant’s understanding of program goals and guidelines.

Letter of Intent (optional): February 22, 2011
Full Proposal: March 22, 2011

FUNDING INFORMATION: This program will utilize the NIH Exploratory/Developmental (R21) award mechanism, and “Just-in-Time” information concepts. The number of awards is contingent upon NIH appropriations, and the submission of a sufficient number of meritorious applications. Direct costs for each component (U.S. or Indian) of the application are limited to $275,000 USD over a two-year period, with no more than $200,000 USD in direct costs allowed in any single year for each component. The NIH will only provide funds to support the U.S. component and the DBT will only provide funds to support the Indian component. A complete budget for the Indian component must be included as part of the Budget Justification section of the application. The total project period for an application submitted in response to this funding opportunity may not exceed two years.

Yuan Liu, Ph.D.
National Institute of Neurological Disorders and Stroke (NINDS)
6001 Executive Boulevard
Bethesda, MD 20892-9523
Telephone: (301) 496-0012
Email: liuyuan@ninds.nih.gov
Web: http://grants.nih.gov/grants/guide/pa-files/PAR-11-099.html

REMARKS: NIH requires that applications to this program be submitted electronically through Grants.gov (http://www.grants.gov). After submission via Grants.gov, applications will be retrieved and processed by the NIH Commons system (https://commons.era.nih.gov/commons/index.jsp). In order to prepare a responsive application, PIs should download both the complete program guidelines (PAR-11-099) and the corresponding application package from Grants.gov as well as the NIH Grants.gov Application Guide (http://grants.nih.gov/grants/funding/424/index.htm). PIs must also be registered Commons users.

For more information about Grants.gov and the NIH Commons, or to register as a Commons user, please contact A. Brink Effgen (abeffgen@bu.edu) in the Office of Sponsored Programs (OSP) at x3-4365. In addition, please contact the OSP Assistant Director assigned to your school or department as soon as possible to coordinate submission through the Grants.gov system.

Complete program guidelines and application material may be obtained from the web site listed above or from the Office of Sponsored Programs (OSP). Please distribute this notice to any faculty or staff members who might be interested in the information. For more information, please contact the OSP at X3-4365 or ospinfo@bu.edu, or visit the OSP web site at http://www.bu.edu/osp.