Metropolitan College
Undergraduate Courses I
Please note, other Schools
and Colleges within the University have different course requirements
for degree candidates. Candidates for degrees in programs other than those
offered by Metropolitan College should receive approval from their respective
Schools and Colleges before registering in Metropolitan College courses. General level assumes no special
level of training and competence beyond that expected of a student meeting
entrance requirements for the degree program. Intermediate level assumes
a level of training and competence beyond that of the normal entering
degree candidate, either through prerequisites or equivalent work elsewhere.
Students in Metropolitan College may receive graduate credit for any
course at the 500-level or above with the consent of their advisors. Students
who have applied or who intend to apply to graduate school at Boston University
or elsewhere should speak to an advisor in the department in which they
plan to enroll for information about requirements, course sequences, and
prerequisites. Because the requirements for graduate-level work differ,
students must obtain approval from the department and from the professor
of each course before they begin the course. Students will not receive
graduate credit from Boston University Graduate School of Arts and Sciences
unless they obtain these approvals. Year course indicates that
the material in the course is conceived as one continuous unit from the
first semester through the second semester. Students who wish to register
for the second semester without having taken the first should check with
the instructor. Students should consult individual course descriptions
for enrollment limitations. See the Metropolitan College Course Schedule and the addenda
for possible changes in courses, fees, days, and hours of class meetings.
A survey of the concepts, principles, and major areas of cultural anthropology.
Comparative examination of institutions, processes of cultural change,
and influence of culture on individual behavior in contemporary non-Western
societies. 4 cr
Biology relevant to the behavioral sciences. Introduces basic
principles of evolutionary biology, animal social behavior, primate adaptations,
human origins, genetic/ hormonal/neural bases of behavior, and issues
of human socioecology and adaptations. Discussions highlight nature-vs.-nurture
issues. 4 cr
Cross-cultural examination of changing gender roles, expectations,
and activities. Focuses on economic, social, political, and ideological
determinants that structure the hierarchy of power and privileges accorded
the thoughts, activities, and experiences of women and men in various
societies. 4 cr A chronological survey of European art from preclassical times through
the end of the Middle Ages. Emphasis on the relation of art to its historical
and cultural context. 4 cr
Continues MET AH 111, but can be taken separately. Chronological survey of European art from the Renaissance to the present. Emphasis on the relation of art to its historical and cultural context. 4 cr
Extensive practical application in basic aspects of photography.
Negative exposure and processing coordinated with print production and
evaluation. Students use their own 35mm camera. Single-lens reflex is
recommended. Cost of materials: approximately $125. 4 cr
Introduction to
the arts of Asia. Emphasis on masterpieces of Asian art and the cultural
and historical context in which they were created. 4 cr
Painting, sculpture, and architecture in Greece from early times
to the end of the Hellenistic period. Interrelationships among art, mythology,
religion, athletics, and history. 4 cr
Painting, sculpture, and architecture in Italy and the Roman
Empire from the Etruscans
to Constantine, the first Christian emperor. Emphasis on art, engineering,
politics, religion, and urban life. 4 cr
Examines photography from a cultural perspective in the nineteenth
and twentieth centuries. Focuses on individual photographers, institutions,
art movements, and historical circumstances that defined the perception
of photography in Europe and America. 4 cr
The expression of man’s relationship to God as symbolized
by cathedral building. The structure as an intangible arrangement of balances
and counterbalances; its role in the evolution of urban life from towns
to cities. 4 cr
The role of the artist and his work in fourteenth- and fifteenth-century
Europe. Emphasis on the rise of humanistic thought and the shift from
a God-centered to
a man-centered society. 4 cr
The artistic masters of the High Renaissance and their patrons,
from Leonardo da Vinci to
El Greco, with an emphasis on social forces and artistic styles in the
sixteenth century. 4 cr
Traces the development of Boston as an urban entity since the
seventeenth century. Emphasis on Boston as a model for American architectural
history from the colonial to the international styles. Surveys the city’s
history from English village to modern megalopolis. 4 cr
An examination of the new concepts of reality that grew out of
the French Revolution, and how these concepts influenced the critical
theories of Impressionist and Post-Impressionist art. 4 cr
Analysis of the work and thought of major masters of twentieth-century
painting, sculpture, architecture, and photography, including the School
of Paris and the New York School. 4 cr
Program faculty selects seminar topics of current interest, usually
with a singular focus, in the field. 4 cr
Detailed
study of Impressionism from 1860s to circa 1900. Emphasis is on French
artists, but Impressionists elsewhere in Europe and America are also considered.
Discusses Impressionism’s sources, Realist underpinnings, stylistic
development, themes, and changes in the 1880s. 4 cr
Introductory survey of digital imaging in the visual arts. Lectures
and slides illustrate historical perspective, and hands-on studio sessions
allow students to create and manipulate digital images. Emphasis on expressing
personal ideas through new imaging techniques. 4 cr
In-depth exploration of the various forces of society, personality,
and media that influence or hinder the creative drive of the artist. Selected
artists and art works studied. 4 cr
The special character, expression, and forces behind the concept
of the “new”
in the arts. The importance of reaction and shock in the twentieth-century
arts of painting, sculpture, theatre, dance, literature, and film. The
role of the artist and the viewer. 4 cr
Prereq: consent of instructor. Independent study on special projects
under faculty guidance. 4 cr
An examination of the arts, institutions, issues, and forces
that shape the contemporary art world. Topics include government support,
cultural policy, museums, curators, critics, artists’ rights, public
art, corporate support, censorship, feminism, and multiculturalism. Stamped
approval required. 4 cr
(See also Arts Administration.)
The life, works, and thought of Michelangelo as a draftsman, architect,
sculptor, painter, and poet are considered in the context of the future
of the Italian Renaissance. 4 cr
Participate in this extraordinary experience as we look at Cuban art
and cultural institutions, the role of the arts and the freedom of intellectual,
artistic, and cultural creation in Cuba. Join us for an intensive residential
course in Cuba for a provocative exchange of ideas and experiences between
students, faculty, and professional artists in Cuba. 4 cr
Drawing on materials from the visual arts, music, literature,
and contemporary criticism, this course examines the blurring boundaries
between art and popular forms of culture in
the closing moments of the twentieth century. Writers, artists, and critics
are included. 4 cr Primarily for non-science majors, but science majors may also
take AS 105 for credit. Historical development of astronomy and observational
methods. The origin and evolution of the universe, stars, pulsars, neutron
stars, planets, and the possibility of extraterrestrial life in our galaxy.
Use of the observatory. 4 cr
Primarily for non-science majors, but science majors may also
take AS 117 for credit. Cosmic evolution from origin of the universe to
formation of stars and planets like our own. Covers origin of life and
its slow evolution toward higher intelligence; possibilities for communication
with other advanced civilizations; and interstellar travel and the colonization
of the galaxy. Observatory use. 4 cr Principles of biology: emphasis on cellular structure, heredity,
development, and organic evolution. Intended for non-majors as well as
for those concentrating in the health and paramedical sciences. Laboratory
course. Three hours lecture, two hours lab. 4 cr
Prereq: MET BI 105 or equivalent. Gross structure of the human
body: skeletal, muscular, nervous, respiratory, circulatory, digestive,
urinary, and reproductive systems. Laboratory course. Assumes year of high school biology and chemistry. For premedical
students and students who plan to concentrate in the natural sciences.
Required of biology concentrators. It is recommended that MET CH 101 and
CH 102 be taken prior
to or concurrently with this sequence. Each course has three hours lecture
and three hours lab. 4 cr each
Course examines the evolution and diversity of life; principles
of ecology and behavior. 4 cr
Course examines cells, genetics, development, physiology, and
neurobiology. 4 cr
Prereq:
MET BI 108 and CH 102. Principles of cellular organization and function:
biological molecules, enzymes, bioenergetics, membranes, motility, regulatory
mechanisms. Three hours lecture, one hour discussion. 4 cr
Prereq:
MET BI 108 or equivalent. MET CH 203 recommended. Principles of heredity
as derived from genetic, biochemical, and cytological evidence in animals,
plants, and microorganisms. Three hours lecture, one hour discussion.
4 cr
Students will conduct basic ecological research in a variety
of habitats. Students will mist-net and band birds, study burying-beetles,
capture bats, and study plants and aquatic diversity around the field
station. Lectures will encompass a wide range of topics including competition,
predation, co-evolution, and community dynamics. Students will investigate
these
theories in the fields of Sargent Center for Outdoor Education. Visiting
scientists will enhance the learning experience by sharing their expertise.
4 cr
Prereq: MET BI 105 or equivalent. Designed for non-biology majors.
Introduction to physiology. Principles of physiology with special reference
to humans. Laboratory course. Three hours lecture, three hours lab. 4
cr
Prereq: MET BI 107. Basic principles of ecology, population dynamics
and behavior, interrelationships of plants and animals and their physical
and chemical environment. Structure and function of ecosystems and community
dynamics. Laboratory course. Three hours lecture, three hours lab. 4 cr
Prereq: MET BI 107. Structure, development, physiology, ecology,
evolution, and economic importance of plants. Field trips. Laboratory
course. Three hours lecture, three hours lab. (Offered alternate years.)
4 cr
Prereq: MET BI 203, BI 206, and CH 204. Major building materials
of living tissues. Principles
of enzymology. Major metabolic pathways. Generation and transfer of metabolic
energy. Transfer of genetic information. Two hours lecture. 2 cr
Prereq: MET BI 108 and BI 203. An introduction to the basic physiological
principles applied across all levels of organization (cell, tissue, organ
system) and intended to prepare the student for more advanced courses
in physiology. Topics include homeostasis, neural, muscle, cardiopulmonary,
renal, endocrine, and reproductive physiology. Three hours lecture, three
hours lab. 4 cr
Prereq: MET BI 107 or equivalent. Ethological approach to animal
behavior, including humans; physiological, ontogenetic, and phylogenetic
causes and adaptive significance of behavior within an evolutionary framework.
Laboratory course. Three hours lecture, three hours lab. 4 cr
Prereq: MET BI 203, CAS BI 315, or equivalent and consent of
instructor. Chemical and physiological principles of hormonal integration
in animals. Three hours lecture,
one hour discussion. 4 cr
Prereq: senior standing, minimum GPA of 3.0 (B) in biology, consent
of instructor, and approval of research outline by Department of Biology.
Laboratory or field research projects in biology may be chosen under supervision
of Department of Biology. Minimum 12 hours per week in laboratory or fieldwork,
not including preparation or evaluation time. Both semesters of research
may count toward concentration credit in biology if two semesters of work
are completed. 4 cr
Prereq: MET BI 203, BI 206, or consent of instructor. Structure,
synthesis, and control of biologically important macromolecules, especially
DNA, RNA, and proteins. Biochemistry of transcription and translation
of genetic material. Introduction to molecular problems peculiar to eukaryotes.
Three hours lecture, one hour discussion. 4 cr Understanding medical terminology is fundamental for anyone working
in the sciences. It is the language of the technician or researcher involved
in biotechnology, biomedical investigations, or health services. Teaches
the analysis and construction of medical words within a context of scientific
concepts. Topics covered include anatomy, blood, cancer medicine, biotechnology,
and pharmacology. 2 cr
Build your medical vocabulary as you learn the anatomy and diseases
of the following systems: digestive, urinary, nervous (including sense
organs), integumentary (skin), and endocrine. 2 cr
This course provides
a foundation of knowledge in the biomedical and clinical laboratory sciences.
Topics covered give students a basic understanding of chemistry, biology,
microbiology, biochemistry, molecular biology, and immunology. An emphasis
on scientific theory, mathematics, statistics, data collection, presentation
of results, and
laboratory safety will be made throughout the course. Upon completion
of this course, students will be able to function in a biomedical laboratory
at an entry level, understand and
follow protocols and be prepared to take more advanced scientific courses.
4 cr
Describes the science of biotechnology, taking the student through
the history of the industry, and covers the basic science of DNA and its
functions, immunology, proteins and their purification, and fundamental
techniques used in the research and development of biotechnological products.
An overview of drug approval by
the FDA. 2 cr
This course will explore topics such as animal cloning,
Prereq: knowledge of biology. This course provides a practical understanding of anatomic structures and coordinates this knowledge with the various functions of the human body. We will also explore regulatory processes that integrate cells, tissues, organs, and systems. Topics include: organization of the body, tissue development, and cellular structure and function as well as the integumentary (skin), skeletal, and muscular systems. The last third of the course focuses on the nervous system. The course will incorporate clinical material throughout, and laboratory exercises will correlate with the lecture material. 4 cr
This course provides an in-depth understanding of the math used in biomedical laboratories. After reviewing fundamental math principles and basic algebra, students will learn the metric system, scientific notation, logarithms, the importance of significant figures in lab calculations, and basic statistics used in data analysis. The course will also cover data presentation in tables and graphs and approaches to solving word problems commonly encountered in the laboratory. 4 cr
Writing concise, cogent, and accurate reports is a critical
element of clinical research and can be a career in itself. Students will
gain an exposure to the wide variety of documents necessary for clinical
research. Emphasis will be on writing protocol and on writing integrated
clinical/statistical reports. Students will develop an outline of these
documents compliant with current regulations. Using this outline, a protocol,
and typical trial data, a complete report will be prepared. 4 cr
Provides
a detailed knowledge of the role of Current Good Manufacturing Practices
(CGMPs) and
a Quality Department in the development and manufacture of biopharmaceutical
products. Topics include the goals and obligations of
the Food and Drug Administration, a review of the CGMP subparts, and the
responsibilities
of a Quality Department in ensuring product quality. 4 cr
This course focuses on the
management and presentation of information and data useful in areas such
as bioinformatics. Database concepts and principles will be covered while
examining the differences between data and information, and exploring
different types of databases. Students will also learn presentation development
and techniques, using instructional design principles, to create presentations
on laboratory projects and
experimental data. Students will also complete laboratory projects using
Microsoft Access
for database management and Microsoft PowerPoint for presentation development.
4 cr
Prereq: MET BI 105 or equivalent (biology for health sciences),
and MET CH 171 or equivalent (general chemistry for health sciences),
or consent of instructor. This course is for undergraduate students familiar
with chemistry and biology. Provides an overview of biochemistry to prepare
students for medical school or for advanced undergraduate or general graduate
science courses. Topics covered include physical properties of biological
molecules; structure and function of proteins, carbohydrates, lipids and
nucleic aides; kinetics and mechanism of enzymatic catalysis; and metabolism.
4 cr
This course examines the FDA’s Quality System regulation (QSr)
for medical devices. We will study the crucial elements of developing
safe and effective medical devices, manufacturing them in a state of control,
and complying with the QSr requirements. We will start our analysis by
looking at management requirements under
the QSr and then establishing subsequent responsibilities for the organization’s
operational departments. 4 cr
This course explores the use of bioinformatics databases and software
as research and educational tools. Students will use data mining tools
to extract DNA and protein sequences from primary and secondary databases.
Software tools will be used to compare and analyze these sequences and
construct gene and protein models for solving research problems related
to molecular evolution, drug discovery, and genetic bases for development
Prerequisite:
general knowledge of biology. This course will introduce students
to eukaryotic cell structure and function. Topics include membrane structure,
intracellular organelles, control of gene expression, cell motility and
transport, cell communication and signaling, cell cycle and apoptosis,
and differentiation. Students will explore the field of cell biology through
readings and presentations. 4 cr Focuses on techniques used to isolate and identify viral pathogens
associated with human disease. Through a series of lectures, the student
takes a functional approach to this subject. Covers the biology, the immune
response to viral infections, the genetics of viral replication, and viral
pathogenesis. 4 cr
Prereq: one year of college biology, one year of college general
chemistry, and organic chemistry; or GMS BT 305. Focuses on the chemistry
of biological systems. The student explores the biochemical reactions
of animals and plants that help maintain homeostasis. In order to understand
the interrelationships of biological pathways in living systems, these
reactions are examined in a functional manner through lectures. 4 cr
Advanced course (for undergraduate or graduate credit) designed
for those considering
a career in clinical or research genetics. Emphasis is on cytogenetics
(chromosome
testing), diagnosis of genetic disease at the molecular level (DNA testing),
study of DNA polymorphism (i.e., paternity identity and forensic testing),
and biochemical and prenatal
testing. Includes some laboratory work. For those seeking graduate credit,
instructor permission is required, and a term paper or class presentation
will be required at the discretion of the instructor(s). 4 cr
Prereq: GMS BT 406 or equivalent or consent of instructor. This
course is a sequel to Clinical Laboratory Genetics (GMS BT 406), providing
students with hands-on exposure to the basic laboratory procedures involved
in cytogenetics. Students obtain, culture, and prepare cells for chromosome
analysis. Students learn to set up blood cultures and manipulate established
cell cultures to prepare and analyze chromosomes using chromosome banding
techniques, FISH, and other procedures. This course will provide a sound
basis for the successful student to seek a job in clinical cytogenetics.
4 cr
Prereq: one year of college biology and one year of college chemistry.
This course emphasizes the molecular and cellular interactions involved
in immune response. Topics covered include antibody structure and function;
applications of monoclonal antibodies in biotechnology and medicine; gene
rearrangements in B and T cells; cellular cooperation and the role of
MHC; tolerance; and immunopathology (hypersensitivity, autoimmunity, transplantation,
AIDS, cancer immunity and immunotherapy). 4 cr
Prereq: GMS BT 408, BT 454 or equivalent or consent of instructor.
This course will introduce students to laboratory techniques based on
immunologic assays commonly used in biological and biomedical research
labs. Techniques covered include Flow Cytometry (FACs), ELISA, cell sorting,
cell proliferation, cell death, and migration assays. This is a practical
lab course, with approximately a half hour of lecture followed by 2.5
hours in the laboratory each class. 4 cr
Prereq: GMS BT 413, GMS BT 305/405, or equivalent, or consent
of instructor. Familiarizes students with the theory and application of
many biochemical techniques involved in protein purification and characterization,
such as chromatography (HPLC, ion exchange, gel permeation, hydrophobic
affinity), electro-phoresis (followed by blotting techniques), and amino
acid analysis. Students learn to think critically about methodology, design
a purification scheme, scale it up, and troubleshoot an existing plan.
Special problems with recombinant proteins are also covered. 4 cr
Prereq: a working knowledge of biology and chemistry. Students
learn the fundamentals of isolation, in vitro translation, DNA and genomic
cloning, and the characterization and utilization of DNA clones. Students
learn to think critically about research methodology and selection of
appropriate techniques to achieve objectives. 4 cr
Prereq: GMS BT 405. This course surveys a variety of toxins and
poisons examining the molecular mechanisms of toxicity and the natural
detoxification system of the body. Topics also include essentials of laboratory
measurements of toxins, current
regulations with regard to toxic waste management, and relevant aspects
of forensics. Chemotherapeutic and antibiotic drugs will be discussed
as agents used to enhance selective toxicity. 4 cr
Prereq: MET BI 105 and MET CH 171, equivalent, or consent of
instructor. Provides the student
with an understanding of clinically important microorganisms. Students
become familiar with the classification, pathogenicity, identification,
and prevention and treatment of diseases caused by bacteria, fungi, and
parasites as well as the workings of a modern clinical microbiology laboratory.
Laboratory course. 4 cr
Focuses on the successful management of
a biochemical laboratory. Topics covered include quality control, record
keeping, process control, computer skills, good laboratory practices,
and communication skills. Guest lecturers from industry, hospitals, and
research
laboratories are featured. 4 cr
Prereq: MET BI 105 or equivalent and GMS BT 305/405 or equivalent
and Internet browser access. This course focuses on mammalian genetics
and DNA structure and analysis. It is intended for students interested
in pursuing a career in laboratory research in an academic or industrial
setting. Topics include the molecular basis of human genetic disease,
DNA structure and analysis, utilization of human genome project data,
and use of Internet-based bioinformatics tools. The class includes lectures,
research laboratory tours, and student presentations. 4 cr
This class will explore the newest information in human genetics
and its legal and bioethical implications. Human genetics is the most
explosive field in medicine today and its present and future involve legal
and ethical decisions only imagined today. The decisions that come from
the issues will be presented to professionals and lay people alike. Using
audiovisuals, actual cases, discussion, and lecture, this class examines
cases that come straight from the headlines. Topics covered include: new
reproductive techniques, genetic diseases, prenatal testing and genetic
testing, DNA fingerprinting, cloning, and DNA technology. 4 cr
This online course explores the new world of assisted reproduction.
Students will examine cases for their ethical and legal implications.
Websites and readings will be provided so students can synthesize information
into thoughtful analyses. Topics will include in vitro fertilization,
surrogacy, frozen embryos, and gene manipulation. The entire process is
taught online. Assignments, including case analyses, quizzes, and papers,
will be turned in over the Internet. 4 cr
Prereq: GMS BT 413/414 or equivalent. This course evaluates how
cutting-edge technologies in molecular biology contribute to unraveling
gene function and biological processes. Students read, discuss, and present
original research papers about transcriptional regulation, intracellular
signaling pathways, cell cycling, apoptosis, cancer, and DNA repair. Technologies
discussed include microarrays, RNA silencing, inducible gene expression
systems, reporter gene assays, mutagenesis, use of green fluorescent protein
for life cell imaging, the creation of transgenic and knock
animals, the Cre/Lox system, and the use of biological databases from
genome projects. Great opportunity to develop and improve your PowerPoint
presentation skills. 4 cr
Explores the role of toxicology in society both as a safeguard
to prevent injury from environmental chemicals and a tool in the investigations
of suspicious deaths. Case studies, guest speakers, and group discussions
will accompany
lectures and demonstrations as students also explore the role of legal
and medical communities as well as governmental agencies in dealing with
issues. 4 cr
Prereq: knowledge of biology and chemistry. This course gives
students a foundation in basic cell culture techniques used in modern
cell culture labs. The topics covered will include aseptic technique,
freezing and thawing of cell stocks, passage and maintenance of cells,
and culture of adherent and suspension cells. Emphasis will be on practical
hands-on experience and much of the class time will be devoted to laboratory
work. A short lecture introduces relevant information and techniques to
be performed in the laboratory. Upon completion of this course, students
will be able to function in a cell culture laboratory at the level of
a novice technician and be able to understand and follow basic cell culture
protocols. 4 cr
Prereq: solid knowledge of basic biochemistry, cell biology, and molecular
biology techniques. This course explores the drug discovery process from
initial decision
on which disease pathways to pursue to the evaluation of potential drugs.
Methodologies used to identify and validate drug targets will be described
with emphasis on biotechnology-based assays and techniques. The course
will also cover different types of therapeutics and the options available
to drug developers. Emphasis will be placed on the issues and challenges
faced in identifying appropriate drug targets and devising studies that
accurately validate these targets. 4 cr Prerequisite: GMS BT 305 or BT 405, GMS BT 413 or BT 443
or equivalent or consent of instructor. Many pathological conditions such
as diabetes and cancer are caused by perturbations in signal transduction
cascades. These cascades convert extracellular signals into changes in
gene expression and alterations in cell physiology. Cellular responses
result from the integration of many different signals. The proteins that
participate in signal transduction cascades interact in a dynamic, regulated
fashion to form multi-protein complexes that allow information processing.
This course will present the major signal transduction pathways and their
crosstalk, as well as their contribution in maintaining cellular homeostasis.
In addition, we will highlight perturbations of these pathways that could
lead to development of different diseases as well as the molecular logic
that underlies current and future therapies. 4 cr
Prereq: GMS BT 413 or equivalent, basic cell culture experience,
or consent of instructor. Cell culture has become an indispensable tool
for all areas of biomedical science. In this course, students will develop
the necessary routine by taking care of particular cell lines throughout
the entire course. At the same time, students will examine their cell
lines using advanced techniques, such as transient and stable transfections,
reporter gene assays, activation of signaling pathways, induction of cell
differentiation, examination of cell cycle and apoptosis, fluorescent
microscopy, and FACS analysis. At the end of the course, each group will
present their findings during a poster session. Laboratory course. 4 cr Prereq: molecular biology or biochemistry or consent of instructor. This
course explores the emerging field of structural biology, including its
implications for rational drug design and nanotechnology. Using interactive
computer models, we will delve into the 3D structure of proteins to understand
their function and the molecular logic of life. Students will build their
molecular thinking skills and explore drug action mechanisms using examples
from immunology, infectious diseases, neurobiology, and cancer biology.
The software we will use is free and can be accessed from anywhere. 4
cr
The course introduces students to cancer biology fundamentals. Topics
include cell proliferation, cell death, the process of metastasis and
tumor progression, oncogenes and tumor suppressor genes, and cancer therapeutics.
This class will explore the latest scientific and clinical research on
cancer through readings and presentations. 4 cr Prereq: MET BI 105, MET CH 107, or equivalent or consent of instructor.
Introduction to the principles of pharmacology including pharmacokinetics
and dose/response relationships. Major classes of therapeutic agents are
covered with attention to their mechanisms of action. Addresses issues
of concern in drug development and the biological bases for population
variability in drug response. 4 cr
This course integrates the analysis and explanation of selected
portions of the Code of Federal Regulations (CFR), applicable to clinical
research during the new drug development process. Because the CFR is translated
as written and unwritten standards, practices and guidelines, the course
uses a detailed case study to interpret the CFR. Each session uses activities
to translate the regulations into experiences. In order to link the classroom
activities with the learners’ work experiences, there will be a
project and presentation on selected topics. 4 cr
This course explains the regulatory requirements for health care
products: drugs, biologics, diagnostics, and devices. The focus is on
U.S. FDA regulations and their impact on product development and marketing
with international requirements. Recommended for students in clinical
research concentration. 4 cr
This course introduces students to the technology, process, and responsibilities
of clinical data management. We will examine study setup, case report
form (CRF) design, and the data life cycle, including data collection;
data validation, coding of adverse events, using standard dictionaries
(such as ICD-9 or MedDRA), data review, and database lock. Data Management
SOP’s will be discussed within this context. An industry-leading
clinical data management system (CDMS) will be utilized. We will also
explore how new technologies, such as electronic data capture (EDC), affect
these processes. 4 cr Introduces the regulatory responsibilities of sponsors, monitors, and
investigators conducting clinical trials. Practical information and exercises
are designed for the clinical trial professional on procedures for ensuring
GCP compliance from an industry perspective. Topics include: identifying
and selecting qualified investigators, obtaining ethical approval to enroll
patients, and initiating sites successfully. Also covers issues related
to collecting required regulatory documentation, verifying high quality
data, maintaining study materials accountability, and reporting serious
adverse events. Group discussions and guest speakers help students learn
the practical skills used in the field. 4 cr
Prereq: GMS BT 570 or equivalent. Covers the history and current
methodologies used in the design and conduct of clinical trials. Topics
include sample selection; data forms and management; patient recruitment,
enrollment, and compliance; and measures of cost effectiveness. 4 cr
Students examine the development and implementation of regulatory as
well as ethical issues involved with conducting clinical trials. Topics
include: use of human subjects, privacy and confidentiality, conflicts
of interest, use of stem cells in research, federal laws affecting laboratories,
and genetic testing of gene and therapy trials. There will also be discussions
on landmark legal cases affecting laboratory scientists. 2 cr Prereq: résumé writing workshop. Directed study
for degree candidates only. Practical, hands-on experience in laboratory
setting. Various credits and fee, as arranged with Director.
Prereq: 16 credits in clinical research and permission of Director.
Directed study offering exposure to the conduct of a clinical trial. Various
credits and fee, as arranged with Director. It is possible to register separately for the lecture component (3 cr) and the laboratory
(1 cr) of several 4-credit courses that have both components. These courses include MET CH 101,
CH 102, CH 203, CH 204, CH 211, and CH 212. However, separate registration is not permitted
if the student is taking the lecture and laboratory components simultaneously.
Prereq: two years of high school algebra. For science concentrators,
premedical students, and students in related fields. Stoichiometry, states
of matter, acids and bases, equilibrium, and selected chemical systems.
Laboratory course. Three hours lecture, one hour discussion, three hours
lab per week, and one hour postlab discussion per week. 4 cr
Prereq: MET CH 101 or equivalent. For science concentrators,
premedical students, and students in related fields. Covers thermodynamics,
atomic structure and bonding, electrochemistry, chemical kinetics, and
selected chemical systems. Laboratory course. Three hours lecture, one
hour discussion, three hours lab, and one hour postlab discussion per
week. 4 cr
Lecture component of MET CH 101. See CH 101 course description. Three hours lecture, one hour discussion
per week. 3 cr
Lecture component of MET CH 102. See CH 102 course description.
Three hours lecture, one hour discussion. 3 cr
Prereq: two years of high school algebra, MET CH 103, or equivalent.
For students who have already taken the lecture portion of CH 101. Three
hours lab, one hour postlab discussion per week. 1 cr
Prereq: MET CH 104 or equivalent. Laboratory component of MET
CH 102. For students who have already taken the lecture portion of CH
102. Three hours lab, one hour postlab discussion per week. 1 cr
Coreq: MET MA 123. A one-semester, terminal general chemistry
course for students who do not require a two-semester sequence. Stoichiometry,
atomic and molecular structure, bonding, chemistry of the solid state,
chemical thermodynamics, and equilibrium. Three hours lecture, one hour
discussion, three-and-a-half hours lab. 4 cr
Primarily for students in allied health professions. Introduction
to chemistry, including separation and purification of matter, atomic
theory, structure of atoms, molecules, and chemical bonding. Laboratory
course. Three hours lecture, one hour discussion per week, three hours
lab weekly, with one hour prelab lecture each week. 4 cr
Prereq: MET CH 171. Primarily for students in the allied health
professions. Organic chemistry, including structure, stereochemistry,
and reactions of carbon compounds. Emphasis on compounds of biochemical
interest. Laboratory course. Three hours lecture, one hour discussion,
three hours lab weekly with one hour prelab lecture. 4 cr
Prereq: MET CH 171 or CH 101, 102. Organic chemistry: structure, stereochemistry,
and reactions of carbon compounds; emphasis on compounds of biochemical
interest. Lecture component of MET CH 172. Three hours lecture, one hour
discussion. 3 cr Prereq: MET CH 102 or equivalent. Laboratory applications of
quantitative chemical analysis. One hour lecture, eight hours lab. 2 cr
Prereq: MET CH 102 or equivalent. Structure and reactivity of
organic compounds. Synthesis, reaction mechanisms, bonding, stereochemistry,
laboratory methods. Coverage of the families of organic compounds, including
molecules of biological interest. Laboratory course. Three hours lecture,
one hour discussion, one hour prelab lecture, and three-and-a-half hours
work period alternate weeks. Laboratory course. 4 cr each
Prereq: MET CH 102 or equivalent. Lecture component of MET CH
203, 204. Structure and reactivity of organic compounds, synthesis, reaction
mechanisms, bonding, and stereochemistry. Coverage of the families of
organic compounds, including molecules of biological importance. Three
hours lecture,
one hour discussion weekly. 3 cr each
Prereq: MET CH 102 and CH 205 or CH 215, or equivalent. Laboratory
component of MET CH 203, 204. An introduction to laboratory techniques,
including experiments in distillation, extraction, chromatography, purification,
derivitization, and synthesis. Laboratory course. One hour prelab lecture
and three-and-a-half hours work period alternate weeks.
1 cr each
Prereq: MET CH 102, CH 108, CH 110, or CH 112; coreq: MET CH
204 or CH 212. Relation of atomic and molecular structure to chemical
properties. Bronsted and Lewis acid/base behavior, redox reactions, bonding
and reactions of main group elements, d-metal complexes including bonding,
spectra, and reaction mechanisms, organometallic chemistry. Three hours
lecture, one hour discussion, four hours lab. 4 cr
Prereq: MET CH 172 or equivalent. Primarily for students in allied
health professions. Biochemistry. Structure and function of biological
macromolecules: polysaccharides, proteins, and nucleic acids; lipids;
enzymes and metabolism; bioenergetics, control mechanisms; hormones; body
fluids; nutrition; and biochemical pathology. Three hours lecture, one
hour discussion. 4 cr
Prereq: MET CH 102 or CAS CH 102, CH 108, CH 110 or CH 112, MET
PY 211, MET MA 124, MET PY 212, MET MA 225. Introduction to thermodynamics,
electro-chemistry, statistical mechanics, chemical kinetics, laws and
structure of gases, liquids, solids, and solutions. Introduction to quantum
mechanics as applied to atomic and molecular systems, including molecular
spectroscopy. Three hours lecture, one hour discussion. 4 cr each
Introductory biochemistry. Protein structure and folding, enzyme
mechanisms, kinetics, and allostery; nucleic acid structure; lipids and
membrane structure; bioenergetics; vitamins and coenzymes; introduction
to intermediary metabolism. Students must register for two sections: lecture
and laboratory. 4 cr CAS and GRS Chemistry Courses Students may take CAS CH 354 Physical Chemistry Laboratory (eight hours per week) with the instructor’s permission. Registration
for this and all other CAS and GRS courses may be made through Metropolitan College. Tuition and fees are charged at the College of Arts
and Sciences and Graduate School of Arts and Sciences rates for day courses.
Classical Studies Introduction to the myths of the ancient classical world, with emphasis
on the patterns of experience, both religious and psychological, from which
they evolved. 4 cr
Published by Trustees of Boston University
Anthropology
Art History
Astronomy
Biology
Biomedical Laboratory and Clinical Sciences
Chemistry
CAS and GRS Chemistry Courses
Classical Studies
Computer Science
Criminal Justice
Earth Sciences
Economics
Science and Engineering Program
English
Executive Bachelor's Degree Completion Program
Undergraduate Degree Completion Program
(Online only)
Geography
History
Interdisciplinary Studies
International Relations
Management Studies
Mathematics
Modern Foreign Languages and Literatures
Philosophy
Physics
Political Science
Psychology
Religion
Sociology
Urban Affairs 
Explanation of Course Number and Level System
Course
NumbersLevel
000–099
non-degree credit
100–199
general undergraduate
200–299
intermediate undergraduate
300–399
advanced undergraduate
400–499
advanced undergraduate
500–599
advanced undergraduate or general graduate
600–699
general graduate
700–799
graduate degree candidates
800–899
advanced graduate
900–999
graduate directed study and research
Anthropology
MET
AN 101 Introduction to Cultural Anthropology
MET
AN 102 Human Behavioral Biology and Evolution (N)
MET
AN 260 Women and Men: Cultural Expectations and Gender Experiences
Art History
MET
AH 111 Survey of Western Art I
MET
AH 112 Survey of Western Art II
MET
AH 233 Greece, Gods, and Art
MET
AH 234 Rome, Emperors, and Art
MET
AH 315 History of Photography
MET
AH 336 God, Man, and Cathedral Building
MET
AH 342 Masters of the Renaissance: Giotto to Botticelli
MET
AH 344 Artists, Princes, and Popes
MET
AH 364 Architecture and City Planning in Old Boston
MET
AH 370 Romanticism Through Post-Impressionism
MET
AH 380 Special Topics in Art History
MET
AH 395 Art, Computers, and Digital Imaging
MET
AH 418 Seminar: Creativity, Imagination, and the Masterpiece
MET
AH 419 Seminar: The Avant-Garde in the Arts
MET
AH 420, 421 Directed Study
MET
AH 517 Seminar: The Art World
MET
AH 546 Studies in Michelangelo
MET AH 588 Arts in Cuba
MET
AH 598 Art and Popular Culture
Astronomy
MET
AS 105 Survey of the Universe (N)
MET
AS 117 Bioastronomy: Cosmic Evolution and the Search for Extraterrestrial
Life (N)
Biology
MET
BI 105 Introductory Biology for Health Sciences (N)
Three hours lecture, two hours lab. 4 cr
MET
BI 107 Biology I: Evolution, Ecology, and Behavior
MET
BI 108 Biology II: Cells, Genetics, Development, and Physiology
MET
BI 207 Introduction to Field Ecology
MET
BI 211 Human Physiology (N)
MET
BI 305 Plant Biology (EBE)
MET
BI 315 Systems Physiology (PER)
MET
BI 407/607 Animal Behavior (EBE)
MET
BI 425/625 General Endocrinology (PER)
MET
BI 491, 492 Research in Biology
MET
BI 552 Molecular Biology (CM)
Biomedical Laboratory and Clinical Sciences
GMS
BT 104 Medical Terminology
GMS
BT 106 Medical Terminology II
GMS
BT 108 Introductory Math for the Laboratory
This course introduces the fundamental math used in biomedical laboratory science. Students will gain a solid understanding of the metric system and its use in the laboratory, scientific notation, and calculations commonly performed in the laboratory. Basic algebra, word problems, significant figures, and data presentation will also be covered. 2 cr
GMS
BT 110 Introduction to Biomedical Laboratory Sciences
stem cell research, genetically modified plants, emerging infectious diseases,
cancer therapies, vaccines, and organ transplantation. Classes will include
lecture, discussions on journal
articles, and student presentations. 2 cr
GMS
BT 201 Anatomy and Physiology
GMS BT 208 Math for the Laboratory
GMS
BT 210 Technical Writing for Clinical Research
GMS
BT 240 Current Good Manufacturing Practices and Quality Assurance
GMS
BT 280 Office Applications in the Laboratory
GMS
BT 305 Introductory Biochemistry
GMS
BT 330 Medical Devices
GMS
BT 336 Applications in Bioinformatics
and disease. 4 crGMS BT 342 Cell Biology
GMS
BT 406 Clinical Laboratory Genetics
GMS BT 407 Cytogenetics Laboratory
GMS
BT 409 Immunology Laboratory
GMS
BT 411 Techniques in Proteomics
GMS
BT 413 Techniques in Molecular Biology
GMS
BT 426 Medical Microbiology
GMS
BT 430 Laboratory Management
GMS
BT 440 Genetics, Ethics, and the Law
GMS
BT 442 Issues in Assisted Reproduction
GMS
BT 443 Advanced Molecular Biology Lecture
GMS BT 450 Forensic Toxicology
GMS
BT 454 Cell Culture Techniques
GMS BT 460 Drug Discovery and Biotechnology
GMS BT 465 Cell Signaling in Health and Disease
GMS
BT 484 Advanced Cell Culture Techniques
GMS BT 495 From Genes to Machines
GMS BT 520 Biology of Cancer
GMS
BT 530 Introductory Pharmacology
GMS BT 531 Clinical Trials Management
GMS
BT 540 Regulatory and Compliance Issues
GMS BT 550 Clinical Data Management
GMS
BT 560 Good Clinical Practices (GCP) in Clinical Research
GMS
BT 575 Design and Conduct of Clinical Trials
GMS BT 580 Legal and Ethical Issues in Clinical Research
GMS
BT 591/592 Directed Study: Biomedical Externship
GMS
BT 594/595 Clinical Research Practicum
Chemistry
MET
CH 101 General Chemistry I (N)
MET
CH 102 General Chemistry II (N)
MET
CH 103 General Chemistry I—Lecture (N)
MET
CH 104 General Chemistry II—Lecture (N)
MET
CH 105 General
Chemistry I—Laboratory (N)
MET
CH 106 General Chemistry II—Laboratory (N)
MET
CH 131 Principles of General Chemistry
MET
CH 171 Life Sciences Chemistry I (N)
MET
CH 172 Life Sciences Chemistry II
MET CH 174 Life Science Chemistry II (NS)
MET
CH 201 Quantitative Analytical Chemistry Laboratory
MET
CH 203, 204 Organic Chemistry
MET
CH 205, 206 Organic Chemistry—Lecture
MET
CH 207, 208 Organic Chemistry—Laboratory
MET
CH 232 Inorganic Chemistry
MET
CH 273 Life Sciences Chemistry III
MET
CH 351, 352 Physical Chemistry
MET CL 213 Greek and Roman Mythology
One Sherborn Street
Boston, MA 02215
26 October
2006
Boston University
Questions
Credits