References – K

Ka SM, Cheng CW, Shui HA, Wu WM, Chang DM, Lin YC and Chen A (2007) Mesangial cells of lupus-prone mice are sensitive to chemokine production. Arthritis Research & Therapy 9 R67

Ka SM, Huang XR, Lan HY, Tsai PY, Yang SM, Shui HA and Chen A (2007) Smad7 gene therapy ameliorates an autoimmune crescentic glomerulonephritis in mice. Journal of the American Society of Nephrology 18 1777-1188

Kaarniranta K, Elo MA, Sironen RK, Karjalainen HM, Helminen HJ and Lammi MJ (2002) Stress responses of mammalian cells to high hydrostatic pressure. Biorheology 40 87-92

Kaarniranta K, Ryhanen T, Karjalainen HM, Lammi MJ, Suuronen T, Huhtala A, Kontkanen M, Terasvirta M, Uusitalo H and Salminen A (2005) Geldanamycin increases 4-hydroxynonenal (HNE)-induced cell death in human retinal pigment epithelial cells. Neuroscience Letters 382 185-190

Kabanov A, Zhu J and Alakhov V (2005) Pluronic block copolymers for gene delivery. Advances in Genetics 53 231-261

Kabashima K, Honda T, Nunokawa Y and Miyachi Y (2004) A new NF-kB inhibitor attenuates a T(H)1 type immune response in a murine model. FEBS Letters 578 36-40

Kabay B, Teke Z, Aytekin FO, Yenisey C, Bir F, Sacar M, Erdem E and Ozden A (2007) Pyrrolidine dithiocarbamate reduces lung injury caused by mesenteric ischemia/reperfusion in a rat model. World Journal of Surgery in press

Kabe Y, Ando K, Hirao S, Yoshida M and Handa H (2005) Redox regulation of NF-kB activation: distinct redox regulation between the cytoplasm and the nucleus.Antioxidants and Redox Signaling 7 395-403

Kabouridis PS, Hasan M, Newson J, Gilroy DW and Lawrence T (2002) Inhibition of NF-kB activity by a membrane-transducing mutant of IkBa. Journal of Immunology 169 2587-2593

Kabrun N, Bumstead N, Hayman MJ and Enrietto PJ (1990) Characterization of a novel promoter insertion in the c-rel locus. Molecular and Cellular Biology 10 4788-4794

Kabrun N and Enrietto PJ (1994) The Rel family of proteins in oncogenesis and differentiation. Seminars in Cancer Biology 5 103-112

Kabrun N, Hodgson JW, Doemer M, Mak G, Franza BR and Enrietto PJ (1991) Interaction of the v-rel protein with an NF-kB DNA binding site. Proceedings of the National Academy of Sciences USA 88 1783-1787

Kabu K, Yamasaki S, Kamimura D, Ito Y, Hasegawa A, Sato E, Kitamura H, Nishida K and Hirano T (2006) Zinc is required for Fc{epsilon}RI-mediated mast cell activation.Journal of Immunology 177 1296-1305

Kaczorowski DJ, Nakao A, Mollen KP, Vallabhaneni R, Sugimoto R, Kohmoto J, Tobita K, Zuckerbraun BS, McCurrey KR, Murase N and Billiar TR (2007) Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion. Transplantation 84 1279-1287

Kadhim HS, Al-Jeboori TI and Tawfik MS (2006) Possible role of nuclear factor kappaB detected by in situ hybridization in the pathogenesis of transitional cell carcinoma of the bladder.
Journal Medical Libanais 54 196-199

Kadoya H, Nagano-Fujii M, Deng L, Nakazono N and Hotta H (2005) Nonstructural proteins 4A and 4B of hepatitis C virus transactivate the interleukin 8 promoter.Microbiolgoy and Immunology 49 265-273

Karoury RM, Hernandez JM, Lasky JA, Toscano Jr WA and Friedman M (2007) Activation of transcription factor IL-6 (NF-IL-6) and nuclear factor-kB (NF-kB) by lipid ozonation products is crucial to interleukin-8 gene expression in human airway epithelial cells. Environmental Toxicology 22 159-168

Kafoury RM and Kelley J (2005) Ozone enhances diesel exhaust particles (DEP)-induced interleukin-8 (IL-8) gene expression in human airway epithelial cells through activation of nuclear factors- kB (NF-kB) and IL-6 (NF-IL6). International Journal of Environmental Research and Public Health 2 403-410

Kafoury RM and Madden MC (2005) Diesel exhaust particles induce the over expression of tumor necrosis factor-a (TNF-a) gene in alveolar macrophages and failed to induce apoptosis through activation of nuclear factor-kB (NF-kB). International Journal of Environmental Research and Public Health 2 107-113

Kagami S, Saeki H, Komine M, Kakinuma T, Nakamura K, Tsunemi Y, Sasaki K, Asashina A and Tamaki K (2006) CCL28 production in HaCaT cells was mediated by different signal pathways from CCL27. Experimental Dermatology 15 95-100

Kagan-Ponomarev MIa (2004) Clinical value of some factors of gene transcription in heart diseases [Article in Russian]. Kardiologiia 44 66-70

Kagemann G, Henrich B, Kuhn M, Kleinert H and Schnorr O (2005) Impact of Mycoplasma hyorhinis infection on l-arginine metabolism: differential regulation of the human and murine iNOS gene. Biology and Chemistry  386 1055-1063

Kagemann G, Sies H and Schnorr O (2007) Limited availability of L: -arginine increases DNA-binding activity of NF-kB and contributes to regulation of iNOS expression. Journal of Molecular Medicine in press

Kagoshima M, Ito K, Cosio B and Adcock IM (2003) Glucocorticoid suppression of nuclear factor-kB: a role for histone modifications. Biochemical Society Transactions 31 60-65

Kagoshima M, Cosio B and Adcock IM (2003) How signaling pathways interact with gene transcription. Monaldi Archives of Chest Disease 59 30-37

Kahlenberg JM, Lundberg KC, Kertesy SB, Qu Y and Dubyak GR (2005) Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kB-driven protein synthesis. Journal of Immunology 175 7611-7622

Kahn AU and Wilson T (1995) Reactive oxygen species as cellular messengers. Current Biology 2 437-445

Kahn-Perlès B, Lipcey C, Lécine P, Olive D and Imbert J (1997) Temporal and subunit-specific modulations of the Rel/NF-kB transcription factors through CD28 costimulation. Journal of Biological Chemistry 272 21774-21783

Kaibori M, Okumura T, Ito S, Oda M, Inoue T and Kamiyama Y (1999) Inhibition of iNOS induction by FK506, but not by cyclosporine, in rat hepatocytes. Transplantation Proceedings 31 804-805

Kaibori M, Sakitani K, Oda M, Kamiyama Y, Masu Y, Nishizawa M, Ito S and Okumura T (1999) Immunosuppressant FK506 inhibits inducible nitric oxide synthase gene expression at a step of NF-kB activation in rat hepatocytes. Journal of Hepatology 30 1138-1145

Kaibori M, Yanagida H, Nakanishi H, Ozaki T, Yoshida H, Matsui K, Hijakawa T, Kamiyama Y and Okumura T (2006) Hepatocyte growth factor stimulates the induction of cytokine-induced neutrophil chemoattractant through the activation of NF-kB in rat hepatocytes. Journal of Surgical Research 130 88-93

Kaibori M, Yanagida H, Nakanishi H, Yokoigawa N, Kwon AH, Okumura T and Kamiyama Y (2004) Effect of hepatocyte growth factor on induction of cytokine-induced neutrophil chemoattractant in rat hepatocytes. Transplantation Proceedings 36 1977-1979

Kaileh M, Vanden Berghe W, Heyerick A, Horion J, Piette J, Libert C, De Keukeleire D, Essawi T and Haegeman G (2007) Withaferin A strongly elicits IKKbeta hyperphosphorylation, concomitant with potent inhibition of its kinase activity.Journal of Biological Chemistry 282 4253-4264

Kairisalo M, Kornonen L, Blomgren K and Lindholm D (2007) X-linked inhibitor of apoptosis protein increases mitochondrial antioxidants through NF-kB activation.Biochemical and Biophysical Research Communications 364 138-144

Kaiser GC, Yan F and Polk DB (1999) Mesalamine blocks tumor necrosis factor growth inhibition and nuclear factor kB activation in mouse colonocytes. Gastroenterology 116 602-609

Kaiser P, Rothwell L, Goodchild M and Bumstead N (2004) The chicken proinflammatory cytokines interleukin-1beta and interleukin-6: differences in gene structure and genetic location compared with their mammalian orthologues. Animal Genetics 35 169-175

Kaiser S and Toborek M (2003) High-efficiency transfection of human endothelial cells mediated by cationic lipids. Journal of Neurochemistry 85 22

Kaiser WJ and Offermann MK (2005) Apoptosis induced by the Toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif. Journal of Immunology 174 4942-4952

Kaisho T, Takeda K, Tsujimura T, Kawai T, Nomura F, Terada N and Akira S (2001) IkB kinase a is essential for mature B cell development and function. Journal of Experimental Medicine 193 417-426

Kaizu T, Nakao A, Tsung A, Toyokawa H, Sahai R, Geller DA and Murase N (2005) Carbon monoxide inhalation ameliorates cold ischemia/reperfusion injury after rat liver transplantation. Surgery 138 229-235

Kajiguchi T, Yamamoto K, Iida S, Ueda R, Emi N andNaoe T (2006) Sustained activation of c-jun-N-terminal kinase plays a critical role in arsenic trioxide-induced cell apoptosis in multiple myeloma cell lines. Cancer Science 97 540-545

Kajino S, Suganuma M, Teranishi F, Takahashi N, Tetsuka T, Ohara H, Itoh M and Okamoto T (2000) Evidence that de novo protein synthesis is dispensable for anti-apoptotic effects of NF-kB. Oncogene 19 2233-2239

Kajita K, Mune T, Kanoh Y, Natsume Y, Ishizawa M, Kawai Y, Yasuda K, Sugiyama C and Ishizuka T (2004) TNFa reduces the expression of peroxisome proliferator-activated receptor gamma (PPARg) via the production of ceramide and activation of atypical PKC. Diabetes Research and Clinical Practice 66 S79-S83

Kajiura F, Sun S, Nomura T, Izumi K, Ueno T, Bando Y, Kuroda N, Han H, Li Y, Matsushima A, Takahama Y, Sakaguchi S, Mitani T and Matsumoto M (2004) NF-kB-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner. Journal of Immunology 172 2067-2075

Kakegawa T, Hayakawa A, Itaya N, Saito H and Kobayashi H (2001) Effect of rapamycin on cytoplasmic accumulation of hetero nuclear ribonucleoprotein C-like unwinding protein 2 [Article in Japanese]. Japanese Journal of Antibiotics 54 Suppl A 93-95

Kako K, Nishikawa M, Yoshida H and Takakura Y (2007) Effects of inflammatory response on in vivo transgene expression by plasmid DNA in mice. Journal of Pharmacological Science in press

Kaku H, Horikawa K, Obata Y, Kato I, Okamoto H, Sakaguchi N, Gerondakis S and Takatsu K (2002) NF-kB is required for CD38-mediated induction of C(gamma)1 germline transcripts in murine B lymphocytes. International Immunology 14 1055-1064

Kakeya H, Onose R, Koshino H, Yoshida A, Kobayashi K, Kageyama S and Osada H (2002) Epoxyquinol A, a highly functionalized pentaketide dimer with antiangiogenic activity isolated from fungal metabolites. Journal of the American Chemical Society 124 3496-3497

Kakisis JD, Liapis CD and Sumpio BE (2004) Effects of cyclic strain on vascular cells. Endothelium 11 17-28

Kalaitzidis D, Davis RE, Rosenwald A, Staudt LM and Gilmore TD (2002) The human B-cell lymphoma cell line RC-K8 has multiple genetic alterations that dysregulate the Rel/NF-kB signal transduction pathway. Oncogene 21 8759-8768

Kalaitzidis D and Gilmore TD (2001) Genomic organization and expression of the rearranged REL proto-oncogene in the human B-cell lymphoma cell line RC-K8. Genes, Chromosomes & Cancer 34 129-135

Kalaitzidis D and Gilmore TD (2005) Transcription factor cross-talk:  estrogen receptor and NF-kB. Trends in Endocrinology and Metabolism 16 46-52

Kalaitzidis D, Ok J, Sulak L, Starczynowski DT and Gilmore TD (2004) Characterization of a human REL-estrogen receptor fusion protein with a reverse conditional transforming activity in chicken spleen cells. Oncogene 23 7580-7587

Kalariya NM, Ramana KV, Srivastava SK and van Kuijk FJ (2007) Carotenoid derived aldehydes-induced oxidative stress causes apoptotic cell death in human retinal pigment epithelial cells. Experimental Eye Research in press

Kalayarasan S, Sriram N and Sudharndiran G (2008) Diallyl sulfide attenuates bleomycin-induced pulmonary fibrosis: Critical role of iNOS, NF-kB, TNF-a and IL-1b. Life Sciences in press

Kalden DH, Scholzen T, Brzoska T and Luger TA (1999) Mechanisms of the antiinflammatory effects of alpha-MSH. Role of transcription factor NF-kB and adhesion molecule expression. Annals of the New York Academy of Sciences 885 254-261

Kaler P, Sasazuki T, Shirazawa S, Augenlicht L and Klampfer L (2008) HDAC2 deficiency sensitizes colon cancer cells to TNFa-induced apoptosis through inhibition of NF-kB activity. Experimental Cell Research in press

Kaliman P, Canicio J, Testar X, Palacin M and Zorzano A (1999) Insulin-like growth factor-II, phosphatidylinositol 3-kinase, nuclear factor-kB and inducible nitric-oxide synthase define a common myogenic signaling pathway. Journal of Biological Chemistry 274 17437-17444

Kalinowski M, Viehofer K, Hamann C, Barry JJ, Kleb B, Klose KJ, Wagner HJ and Alfke H (2005) Local administration of NF-kB decoy oligonucleotides to prevent restenosis after balloon angioplasty: an experimental study in New Zealand white rabbits.Cardiovascular and Interventional Radiology 28 331-337

Kalli K, Huntoon C, Bell M and McKean DJ (1998) Mechanism responsible for T-cell antigen receptor- and CD28- or Interleukin 1 (IL-1) receptor-initiated regulation of IL-2 gene expression by NF-kB. Molecular and Cellular Biology 18 3140-3148

Kalman J, Kudchodkar BJ, Krishnamoorthy R, Dory L, Lacko AG and Agarwal N (2001) High cholesterol diet down regulates the activity of activator protein- 1 but not nuclear factor-kappaB in rabbit brain. Life Sciences 68 1495-1503

Kalogeris T, Gray L, Laroux, FS, Cockrell A, Fuseler J, Conner EM, Brand S and Grisham MB (1999) Selective proteasome inhibitors as anti-inflammatory agents. Expert Opinion in Investigative Drugs 8 1397-1407

Kalogeris TJ, Kevil CG, Laroux FS, Coe LL, Phifer TJ and Alexander JS (1999) Differential monocyte adhesion and adhesion molecule expression in venous and arterial endothelial cells. American Journal of Physiology 276 L9-L19

Kalpana S, Dhananjaay S, Anju B, Lilly G and Sai Ram M (2008) Cobalt chloride attenuates hypobaric hypoxia induced vascular leakage in rat brain: molecular mechanisms of action of cobalt chloride. Toxicology and Applied Pharmacology in press

Kalra D, Baumgarten G, Dibbs Z, Seta Y, Sivasubramanian N and Mann DL (2000) Nitric oxide provokes tumor necrosis factor-alpha expression in adult feline myocardium through a cGMP-dependent pathway. Circulation 102 1302-1307

Kalra N, Bhui K, Roy P, Srivastava S, George J, Prasad S and Shukla Y (2007) Regulation of p53, nuclear factor kB and cyclooxygenase-2 expression by bromelain through targeting mitogen-activated protein kinase pathway in mouse skin. Toxicology and Applied Pharmacology in press

Kalra N, Seth K, Prasad S, Singh M, Pant AB and Shukla Y (2007) Theaflavins induced apoptosis of LNCaP cells is mediated through induction of p53, down-regulation of NF-kB and mitogen-activated protein kinases pathways. Life Sciences 80 2137-2140

Kaltschmidt B and Kaltschmidt C (2000) Constitutive NF-kB activity is modulated via neuron-astroglia interaction. Experimental Brain Research 130 100-104

Kaltschmidt B, Baeuerle PA and Kaltschmidt C (1993) Potential involvement of the transcription factor NF-kB in neurological disorders. Molecular Aspects of Medicine 14 171-190

Kaltschmidt B, Deller T, Frotscher M and Kaltschmidt C (2000) Ultrastructural localization of activated NF-kB in granule cells of the rat fascia dentata. Neuroreport 11 839-844

Kaltschmidt B, Heinrich M and Kaltschmidt C (2002) Stimulus-dependent activation of NF-kB specifies apoptosis or neuroprotection in cerebellar granule cells. Neuromolecular Medicine 2 299-309

Kaltschmidt B, Kaltschmidt C, Hehner SP, Dröge W and Schmitz ML (1999) Repression of NF-kB impairs HeLa cell proliferation by functional interference with cell cycle checkpoint regulators. Oncogene 18 3213-3225

Kaltschmidt B, Linker RA, Deng J, Kaltschmidt C (2002) Cyclooxygenase-2 is a neuronal target gene of NF-kB. BMC Molecular Biology 3 16

Kaltschmidt B, Ndiaye D, Korte M, Pothion S, Arbibe L, Prullage M, Pfeiffer J, Lindecke A, Staiger V, Israel A, Kaltschmidt  and Memet S (2006) NF-kB regulates spatial memory formation and synaptic plasticity through protein kinase A/CREB signaling. Molecular and Cellular Biology 26 2936-2946

Kaltschmidt B, Uherek M, Wellmann H, Volk B and Kaltschmidt C (1999) Inhibition of NF-kB potentiates amyloid b-mediated neuronal apoptosis. Proceedings of the National Academy of Sciences USA 96 9409-9414

Kaltschmidt B, Widera D and Kaltschmidt C (2005) Signaling via NF-kB in the nervous system. Biochimica et Biophysica Acta 1745 287-299

Kaltschmidt C, Kaltschmidt B and Baeuerle PA (1993) Brain synapses contain inducible forms of the transcription factor NF-kB. Mechanisms of Development 43 135-147

Kaltschmidt C, Kaltschmidt B and Baeuerle PA (1995) Stimulation of ionotropic glutamate receptors activates transcription factor NF-kB in primary neurons. Proceedings of the National Academy of Sciences USA 92 9618-9622

Kaltschmidt C, Kaltschmidt B, Henkel T, Stockinger H and Baeuerle PA (1995) Selective recognition of the activated form of transcription factor NF-kB by a monoclonal antibody. Biological Chemistry Hoppe-Seyler 376 9-16

Kaltschmidt C, Kaltschmidt B, Lannes-Vieira J, Kreuzberg G, Wekerle H, Baeuerle PA and Gehrmann J (1994) Activation of transcription factor NF-kB in microglia during experimental autoimmune encephalomyelitis. Journal of Neuroimmunology 55 99-106

Kaltschmidt C, Kaltschmidt B, Neumann H, Wekerle H and Baeuerle PA (1994) Constitutive NF-kB activity in neurons. Molecular and Cellular Biology 14 3981-3992

Kaltschmidt C, Kaltschmidt B, Volk B and Baeuerle PA (1997) Transcription factor NF-kB is activated in primary neurons by amyloid bA4 and in neurons surrounding early plaques from Alzheimer disease patients. Proceedings of the National Academy of Sciences USA 94 2642-2647

Kalvakolanu DVR and Sen GC (1993) Differentiation-dependent activation of interferon-stimulated gene factors and transcription factor NF-kB in mouse embryonal carcinoma cells. Proceedings of the National Academy of Sciences USA 90 3167-3171

Kalyanasundaram A, Elmore JR, Manazer JR, Golden A, Franklin DP, Galt SW, Zakhary EM and Carey DJ (2006) Simvastatin suppresses experimental aortic aneurysm expansion. Journal of Vascular Surgery 43 117-117

Kam AY, Liu AM and Wong YH (2007) Formyl peptide-receptor like-1 requires lipid raft and extracellular signal-regulated protein kinase to activate inhibitor-kappaB kinase in human U87 astrocytoma cells. Journal of Neurochemistry 103 1553-1566

Kamachi F, Yanai M, Ban HS, Ishihara K, Hong J, Ohuchi K and Hirasawa N (2007) Involvement of Na(+)/H(+) exchangers in induction of cyclooxygenase-2 by vacuolar-type (H(+))-ATPase inhibitors in RAW 264 cells. FEBS Letters 581 4633-4638

Kamada N, Maeda K, Inoue N, Hisamatsu T, Okamoto S, Hong KS, Yamada T, Watanabe N, Tsuchimoto K, Ogata H and Hibi T (2007) Non-pathogenic Escherichia coli strain Nissle 1917 inhibits signal transduction in intestinal epithelial cells. Infection and Immunity in press

Kamat AM, Sethi G and Aggarwal BB (2007) Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kB and nuclear factor-kB-regulated gene products in IFN-a-sensitive and IFN-a-resistant human bladder cancer cells. Molecular Cancer Therapeutics 6 1022-1030

Kamata H, Honda SI, Maeda S, Chang L, Hirata H and Karin M (2005) Reactive oxygen species promote TNFa-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 120 649-661

Kamata H, Manabe T, Kakuta J, Oka S and Hirata H (2002) Multiple redox regulation of the cellular signaling system linked to AP-1 and NFkB: effects of N-acetylcysteine and H2O2 on the receptor tyrosine kinases, the MAP kinase cascade, and IkB kinases. Annals of the New York Academy of Sciences 973 419-422

Kamata H, Manabe T, Oka S, Kamata K and Hirata H (2002) Hydrogen peroxide activates IkB kinases through phosphorylation of serine residues in the activation loops. FEBS Letters 519 231-237

Kamata K, Okamoto S, Oka S, Kamata H, Yagisawa H and Hirata H (2001) Cycloprodigiosin hydrocloride suppresses tumor necrosis factor (TNF) alpha-induced transcriptional activation by NF-kB. FEBS Letters 507 74-80

Kamens J and Brent R (1991) A yeast transcription assay defines distinct Rel and Dorsal DNA recognition sequences. New Biologist 3 1005-1013

Kamens J, Richardson P, Mosialos G, Brent R and Gilmore T (1990) Oncogenic transformation by vRel requires an amino-terminal activation domain. Molecular and Cellular Biology 10 2840-2847

Kamer S, Ren Q and Dicker AP (2008) Differential radiation sensitization of human cervical cancer cell lines by the proteasome inhibitor velcade (bortezomib, PS-341). Archives of Gynecology and Obstetrics in press

Kameyama N, Arisawa S, Ueyama J, Kagota S, Shinozuka K, Hattori A, Tatsumi Y, Hayashi H, Takagi K and Wakusawa S (2008) Increase in P-glycoprotein accompanied by activation of protein kinase Calpha and NF-kB p65 in the livers of rats with streptozotocin-induced diabetes. Biocimica et Biophysica Acta in press

Kamiyama H, Usui T, Sakurai H, Shoji M, Hayashi Y, Kakeya N and Osada H (2008) Epoxyquinol B, a naturally occurring pentaketide dimer, inhibits NF-kB signaling by crosslinking TAK1. Bioscience Biotechnology and Biochemistry in press

Kammanadiminti SJ and Chadee K (2006) Suppression of NF-kB activation by Entameba histolytica in intestinal epithelial cells is mediated by heat shock protein 27.Journal of Biological Chemistry 281 26069-26080

Kammanadiminti SJ, Dey I and Chadee K (2007) Induction of monocyte chemotactic protein-1 in colonic epithelial cells by Entamoeba histolytica is mediated via PI3 kinase/p65 pathway. Infection and Immunity 75 1765-1770

Kammanadiminti SJ, Mann BJ, Dutil L and Chadee K (2003) Regulation of Toll-like receptor-2 expression by the Gal-lectin of Entamoeba histolytica. FASEB Journal 18 155-157

Kamon J, Yamauchi T, Muto S, Takekawa S, Ito Y, Hada Y, Ogawa W, Itai A, Kasuga M, Tobe K and Kadowaki T (2004) A novel IKKbeta inhibitor stimulates adiponectin levels and ameliorates obesity-linked insulin resistance. Biochemical and Biophysical Research Communications 323 242-248

Kameoka M, Ota K, Tetsuka T, Tanaka Y, Itaya A, Okamoto T and Yoshihara K (2000) Evidence for regulation of NF-kB by poly(ADP-ribose) polymerase. Biochemical Journal 346 641-649

Kameoka M, Tanaka Y, Ota K, Itaya A and Yoshihara K (1999) Poly (ADP-ribose) polymerase is involved in PMA-induced activation of HIV-1 in U1 cells by modulating the LTR function. Biochemical and Biophysical Research Communications 262 285-289

Kamezaki K, Shimoda K, Numata A, Matsuda T, Nakayama KI and Harada M (2004) The role of Tyk2, Stat1 and Stat4 in LPS-induced endotoxin signals. International Immunology 16 1173-1179

Kamijo S, Nakajima A, Ikeda K, Aoki K, Ohya K, Akiba H, Yagita H and Okumura K (2006) Amelioration of bone loss in collagen-induced arthritis by neutralizing anti-RANKL monoclonal antibody. Biochemical and Biophysical Research Communications in press

Kamine J and Chinnadurai G (1992) Synergistic activation of the human immunodeficiency virus type 1 promoter by the viral tat protein and cellular transcription factor Sp1. Journal of Virology 66 3932-3936

Kamiya S, Nakamura C, Fukawa T, Ono K, Ohwaki T, Yoshimoto T and Wada S (2007) Effects of IL-23 and IL-27 on osteoblasts and osteoclasts: inhibitory effects on osteoclast differentiation.
Journal of Bone and Mineral Metabolism 25 277-285

Kammanadiminti SJ and Chadee K (2006) Suppression of NF-kB activation by Entamoeba hisotlytica in intestinal epithelial cells is mediated by heat shock protein 27. Journal of Biological Chemistry 281 26069-26080

Kammanadiminti SJ and Chadee K (2007) Induction of monocyte chemotactic protein-1 in colonic epithelial cells by Entamoeba histolytica is mediated via PI3 kinase/P65 pathway. Infection and Immunity in press

Kammanadiminti SJ, Mann BJ, Dutil L and Chadee K (2003) Regulation of Toll-like receptor-2 expression by the Gal-lectin of Entamoeba histolytica. FASEB Journal 18 155-157

Kamaohara H, Takahashi M, Ishiko T, Ogawa M and Baba H (2007) Induction of interleukin-8 (CXCL-8) by tumor necrosis factor-a and leukemia inhibitory factor in pancreatic carcinoma cells: impact of CXCL-8 as an autocrine growth factor.International Journal of Oncology 31 627-632

Kamolmatyakul S, Chen W, Yang S, Abe Y, Moroi R, Ashique AM and Li YP (2004) IL-1{alpha} Stimulates cathepsin K expression in osteoclasts via the tyrosine kinase-NF-kB pathway. Journal of Dental Research 83 791-796

Kampf C and Roomans GM (2001) Effects of hypochlorite on cultured respiratory epithelial cells. Free Radical Research 34 499-511

Kamthong PJ and Wu M (2001) Inhibitor of nuclear factor-kB induction by cAMP antagonizes interleukin-1-induced human macrophage-colony-stimulating-factor expression. Biochemical Journal 356 525-530

Kan H, Xie Z and Finkel MS (1999) TNF-a enhances cardiac myocyte NO production through MAP kinase-mediated NF-kB activation. American Journal of Physiology 277 H1641-H1646

Kanai K, Asano K, Hisamitsu T and Suzaki H (2004) Suppression of matrix metalloproteinase production from nasal fibroblasts by macrolide antibiotics in vitro. European Repiratory Journal 23 671-678

Kanai KI, Asano K, Hisamitsu T and Suzaki H (2004) Suppression of matrix metalloproteinase-9 production from neutrophils by a macrolide antibiotic, roxithromycin, in vitro. Mediators of Inflammation 13 313-319

Kanai KI, Asano K, Watanabe S, Kyo Y and Suzaki H (2006) Epinastine hydrochloride antagonism against interleukin-4-mediated T cell cytokine imbalance in vitro. International Archives of Allergy and Immunology 140 43-52

Kanai M, Konda Y, Nakajima T, Izumi Y, Takeuchi T and Chiba T (2001) TGF-a inhibits apoptosis of murine gastric pit cells through an NF-kB-dependent pathway. Gastroenterology 121 56-67

Kanakaraj P, Migone TS, Nardelli B, Ullrich S, Li Y, Olsen HS, Salcedo TW, Kaufman T, Cochrane E, Gan Y, Hilbert DM and Giri J (2001) BLyS bind to B cells with high affinity and induces activation of the transcription factors NF-kB and Elf1. Cytokine 13 25-31

Kanakaraj P, Ngo K, Wu Y, Angulo A, Ghazal P, Harris CA, Siekierka JJ, Peterson PA and Fung-Leung WP (1999) Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice. Journal of Experimental Medicine 189 1129-1138

Kanakiriya SK, Croatt AJ, Haggard JJ, Ingelfinger JR, Tang SS, Alam J and Nath KA (2003) Heme: a novel inducer of MCP-1 through HO-dependent and HO-independent mechanisms. American Journal of Physiology: Renal Physiology 284 F546-F554

Kanamaru C, Yasuda H, Takeda M, Ueda N, Suzuki J, Tsuchida T, Mashima H, Ohnishi H and Fujita T (2001) Smad7 is induced by norepinephrine and protects rat hepatocytes from activin A-induced growth inhibition. Journal of Biological Chemistry 276 45636-45641

Kanamaru F, Youngnak P, Hashiguchi M, Nishioka T, Takahashi T, Sakaguchi S, Ishikawa I and Azuma M (2004) Costimulation via glucocorticoid-induced TNF receptor in both conventional and CD25+ regulatory CD4+ T cells. Journal of Immunology 172 7306-7314

Kanamori M, Kai C, Hayashizaki Y and Suzuki H (2002) NF-kB activator Act1 associates with IL-1/Toll pathway adaptor molecule TRAF6. FEBS Letters 532 241-246

Kanatani M, Sugimoto T, Kano J, Kanzawa M and Chihara K (2003) Effect of high phosphate concentration on osteoclast differentiation as well as bone-resorbing activity. Journal of Cellular Physiology 196 180-189

Kanatani M, Sugimoto T, Sowa H, Kobayashi T, Kanzawa M and Chihara K (2004) Thyroid hormone stimulates osteoclast differentiation by a mechanism independent of RANKL-RANK interaction. Journal of Cellular Physiology 201 17-25

Kanauchi O, Andoh A, Iwanaga T, Fujiyama Y, Mitsuyama K, Toyonaga A and Bamba T (1999) Germinated barley foodstuffs attenuate colonic mucosal damage and mucosal nuclear factor kappa B activity in a spontaneous colitis model. Journal of Gastroenterology and Hepatology 14 1173-1179

Kanayama A, Inoue JI, Konishi YS, Shimizu M and Miyamoto Y (2002) Oxidation of Ikappa Balpha at Methionine 45 is one cause of taurine chloramine-induced inhibition of NF kB activation. Journal of Biological Chemistry 277 24049-24056

Kanayama A and Miyamoto Y (2007) Apoptosis triggered by phagocytosis-related oxidative stress through FLIPS down-regulation and JNK activation. Journal ofLeukocyte Biology 82 1344-1352

Kanayama A, Seth RB, Sun L, Ea CK, Hong M, Shaito A, Chiu YH, Deng L and Chen ZJ (2004) TAB2 and TAB3 activate the NF-kB pathway through binding to polyubiquitin chains. Molecular Cell 15 535-548

Kanayama S, Yamada Y, Onogi A, Shigetomi H, Ueda S, Tsuji Y, Haruta S, Kawaguchi R, Yoshida S, Sakata M, Sado T, Kitanaka T, Oi H, Yagyu T and Kobayahsi H (2007) Bikunin suppresses expression of pro-inflammatory cytokines induced by lipopolysaccharide in neutrophils. Journal of Endotoxin Research 13 369-376

Kanazawa K, Azuma Y, Nakano H and Kudo A (2003) TRAF5 functions in both RANKL- and TNFalpha-induced osteoclastogenesis. Journal of Bone and Mineral Research 18 443-450

Kanazawa K and Kudo A (2005) TRAF2 is essential for TNF-a-induced osteoclastogenesis. Journal of Bone and Mineral Research 20 840-847

Kanazawa N (2007) Clinical features of Blau syndrome and early-onset sarcoidosis and associating CARD15/NOD2 gene mutations. Nihon Rinsho Meneki Gakkai Kaishi 30 123-132

Kanazawa N, Okafuji I, Kambe N, Nishikomori R, Nakata-Hizume M, Nagai S, Fuji A, Yuasa T, Manki A, Sakurai Y, Nakajima M, Kobayashi H, Fujiwara I, Tsutsumi H, Utani A, Nishigori C, Heike T, Nakahata T and Miyachi Y (2005) Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kB activation: common genetic etiology with Blau syndrome. Blood 105 1195-1197
Kanazawa T, Takashima Y, Hirayama S, and Okada H (2008) Effects of menstrual cycle on gene transfection through mouse vagina for DNA vaccine. International Journal of Pharmacology in press

Kanda K, Hu HM, Zhang L, Grandchamps J and Boxer LM (2000) NF-kB activity is required for the deregulation of c-myc expression by the immunoglobulin heavy chain enhancer. Journal of Biological Chemistry 41 32388-32346

Kanda N, Koike S and Watanabe S (2005) IL-17 suppresses TNF-a-induced CCL27 production through induction of COX-2 in human keratinocytes. Journal of Allergy and Clinical Immunology 116 1144-1150

Kanda N, Mitsui H and Watanabe S (2004) Prostaglandin E2 suppresses CCL27 production through EP2 and EP3 receptors in human keratinocytes. Journal of Allergy and Clinical Immunology 114 1403-1409

Kanda N, Shimizu T, Tada Y and Watanabe S (2007) IL-18 enhances IFN-g-induced production of CXCL9, CXCL10, and CXCL11 in human keratinocytes. European Journal of Immunology 37 338-350

Kanda N and Watanabe S (2004) Histamine enhances the production of granulocyte-macrophage colony-stimulating factor via protein kinase Calpha and extracellular signal-regulated kinase in human keratinocytes. Journal of Investigative Dermatology 122 863-872

Kanda N and Watanabe S (2006) Suppressive effects of antimycotics on tumor necrosis factor-alpha-induced CCL27, CCL2, and CCL5 production in human keratinocytes.Biochemical Pharmacology 72 463-473

Kanda N and Watanabe S (2007) Prolactin enhances interferon-g-induced production of CXCL9, CXCL10, and CXCL11 in human keratinocytes. Endocrinology 148 2317-2325

Kanda N, and Watanabe S (2007) Leukotriene B(4) enhances tumour necrosis factor-alpha-induced CCL27 production in human keratinocytes. Clinical and Experimental Allergy 37 1074-1082

Kanda N and Watanabe S (2007) Histamine enhances the production of human beta-defensin-2 in human keratinocytes. American Journal of Physiology: Cell Physiology in press

Kanda N and Watanabe S (2008) IL-12, IL-23, and IL-27 enhance human beta-defensin-2 production in human keratinocytes. European Journal of Immunology in press

Kanda N and Watanabe S (2008) Leptin enhances human beta-defensin-2 production in human keratinocytes. Endocrinology in press

Kanda T, Yokosuka O, Kato N, Imazeki F, Fujiwara K, Kawai S, Saisho H and Omata M (2003) Hepatitis A virus VP3 may activate serum response element associated transcription. Scandanavian Journal of Gastroenterology 38 307-313

Kanda T, Yokosuka O, Nagao K and Saisho H (2006) State of hepatitis C viral replication enhances activation of NF-kB- and AP-1-singaling induced by hepatitis B virus X. Cancer Letters 234 143-148

Kandarian SC and Jackman RW (2006) Intracellular signaling during skeletal muscle atrophy. Muscle Nerve 33 155-165

Kandel ES, Lu T, Wan Y, Agarwal MK, Jackson MW and Stark GR (2005) Mutagenesis by reversible promoter insertion to study the activation of NF-kB. Proceedings of the National Academy of Sciences USA 102 6425-6430

Kandimalla ER, Bhagat L, Wang D, Yu D, Zhu FG, Tang J, Wang H, Huang P, Zhang R and Agrawal S (2003) Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles. Nucleic Acids Research 31 2393-2400

Kandimalla ER, Bhagat L, Yu D, Cong Y, Tang J and Agrawal S (2002) Conjugation of ligands at the 5′-end of CpG DNA affects immunostimulatory activity. Bioconjug Chem 13 966-974

Kandimalla ER, Bhagat L, Zhu FG, Yu D, Cong YP, Wang D, Tang JX, Tang JY, Knetter CF, Lien E and Agrawal S (2003) A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif. Proceedings of the National Academy of Sciences USA 100 14303-14308

Kandouz M, Nie D, Pidgeon GP, Krishnamoorthy S, Maddipati KR and Honn KV (2003) Platelet-type 12-lipoxygenase activates NF-kB in prostate cancer cells. Prostaglandins and Other Lipid Mediators 71 189-204

Kane CM, Cervi L, Sun J, McKee AS, Masek KS, Shapira S, Hunter CA and Pearce EJ (2004) Helminth antigens modulate TLR-initiated dendritic cell activation. Journal of Immunology 173 7454-7461

Kane LP, Lin J and Weiss A (2002) It’s all Rel-ative: NF-kB and CD28 costimulation of T-cell activation. Trends in Immunology 23 413-420

Kane LP, Mollenauer MN, Xu Z, Turck CW and Weiss A (2002) Akt-dependent phosphorylation specifically regulates Cot induction of NF-kB-dependent transcription. Molecular and Cellular Biology 22 5962-5974

Kane LP, Shapiro VS, Stokoe D and Weiss A (1999) Induction of NF-kB by the Akt/PKB kinase. Current Biology 9 601-604

Kanegae Y, Taveres AT, Belmonte JCI and Verma IM (1998) Role of Rel/NF-kB transcription factors during the outgrowth of the vertebrate limb. Nature 392 611-614

Kanekiyo M, Itoh N, Kawasaki A, Tanaka J, Nakanishi T and Tanaka K (2001) Zinc-induced activation of the human cytomegalovirus major immediate-early promoter is mediated by metallothionein and nuclear factor-kB. Toxicology and Applied Pharmacology 173 146-153

Kaneko K, Smetana-Just U, Matsui M, Young AR, John S, Norval M and Walker SL (2008) cis-Urocanic acid initiates gene transcription in primary human keratinocytes. Journal of Immunology 181 217-224

Kaneko M, Niinuma Y and Nomura Y (2003) Activation signal of nuclear factor-kB in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2. Biological & Pharmaceutical Bulletin 26 931-935

Kaneko M, Takahashi T, Niinuma Y and Nomura Y (2004) Manganese superoxide dismutase is induced by endoplasmic reticulum stress through IRE1-mediated nuclear factor (NF)-kB and AP-1 activation. Biological & Pharmaceutical Bulletin 27 1202-1206

Kaneko T, Fujii S, Matsumoto A, Goto D, Makita N, Hamada J, Moriuchi T and Kitabatake A (2003) Induction of tissue factor expression in endothelial cells by basic fibroblast growth factor and its modulation by fenofibric acid. Thrombosis Journal 1 6

Kaneko T and Silverman N (2005) Bacterial recognition and signalling by the Drosophila IMD pathway. Cellular Microbiology 7 461-469

Kaneko T, Yano T, Aggarwal K, Lim JH, Ueda K, Oshima Y, Peach C, Erturk-Hasdemir D, Godlman WE, Oh BH, Kurata S and Silverman N (2006) PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan.
Nature Immunology 7 715-723

Kaneko Y, Furukawa S, Tanaka H and Yamakawa M (2007) Expression of antimicrobial peptide genes encoding enbocin and gloverin isoforms in the silkworm, Bombyx mori.Bioscience, Biotechnology, and Biochemistry in press

Kanekura T, Goora S, Kirtikara K and Ballou LR (2002) The involvement of NF-kB in the constitutive overexpression of cyclooxygenase-2 in cyclooxygenase-1 null cells. Biochimica et Biophysica Acta 1542 14-22

Kanematsu M, Yoshimura K, Takaoki M and Sato A (2002) Vector-averaged gravity regulates gene expression of receptor activator of NF-kB (RANK) ligand and osteoprotegerin in bone marrow stromal cells via cyclic AMP/protein kinase A pathway. Bone 30 553-558

Kanetaka Y, Hayashida M, Hoshika A, Yanase N and Mizuguchi J (2007) Interferon-a induces transient upregulation of c-FLIP through NF-kB activation. Experimental Cell Research in press

Kang BN, Jude JA, Panethieri Jr RA, Walseth TF and Kannan MS (2008) Glucocorticoid regulation of CD38 expression in human airway smotth muscle cells: role of dual specificiaty phosphatase 1. American Journal of Physiology: Lung Cell and Molecular Physiology in press

Kang B, Liang Y, Shan Y, Guo M, Liu S, Fu X, Cao H, Wu M and Wang H (2005) SIRPalpha negatively regulates differentiation of PC12 cell. Brain Research Molecular Brain Research 138 205-214

Kang BN, Tirumurugaan KG, Deshpande DA, Amrani Y, Panettieri RA, Walseth TF and Kannan MS (2006) Transcriptional regulation of CD38 expression by tumor necrosis factor-a in human airway smooth muscle cells: role of NF-kB and sensitivity to glucocorticoids. FASEB Journal 20 1000-1002

Kang BP, Frencher S, Reddy V, Kessler A, Malhotra A and Meggs LG (2002) High glucose promotes mesangial cell apoptosis by an oxidant dependent mechanism. American Journal of Physiology: Renal Physiology 284 F455-F466

Kang BY, Chung SW and Kim TS (2001) Inhibition of interleukin-12 production in lipopolysaccharide-activated mouse macrophages by parthenolide, a predominant sesquiterpene lactone in Tanacetum parthenium: involvement of nuclear factor-kB. Immunology Letters 77 159-163

Kang BY, Chung SW, Chung W, Im S, Hwang SY and Kim TS (1999) Inhibition of interleukin-12 production in lipopolysaccharide-activated macrophages by curcumin. European Journal of Pharmacology 384 191-195

Kang BY, Chung SW, Im SY, Hwang SY and Kim TS (1999) Chloromethyl ketones inhibit interleukin-12 production in mouse macrophages stimulated with lipopolysaccharide. Immunology Letters 70 135-138

Kang BY, Chung SW, Kim SH, Cho D and Kim TS (2003) Involvement of nuclear factor-kB in the inhibition of interleukin-12 production from mouse macrophages by baicalein, a flavonoid in Scutellaria baicalensis. Planta Med 69 687-691

Kang BY, Kim E and Kim TS (2005) Regulatory mechanisms and their therapeutic implications of interleukin-12 production in immune cells. Cellular Signaling 17 665-673

Kang BY, Kim S, Lee KH, Lee YS, Hong I, Lee MO, Min D, Chang I, Hwang JS, Park JS, Kim DH and Kim BG (2008) Transcriptional profiling in human HaCaT keratinocytes in response to kaempferol and identification of potential transcription factors for regulating differential gene expression. Experimental and Molecular Medicine 40 208-219

Kang BY, Kim SH, Cho D and Kim TS (2005) Inhibition of interleukin-12 production in mouse macrophages via decreased nuclear factor-kappaB DNA binding activity by myricetin, a naturally occurring flavonoid. Archives in Pharmacal Research 28 274-279

Kang BY, Miaw SC and Ho IC (2005) ROG negatively regulates T-cell activation but is dispensable for Th-cell differentiation. Molecular and Cellular Biology 25 554-562

Kang CD, Han CS, Kim KW, Do IR, Kim CM, Kim SH, Lee EY and Chung BS (1998) Activation of NF-kB mediates the PMA-induced differentiation of K562 cells. Cancer Letters 132 99-106

Kang C-Y and Temin HM (1973) Lack of sequence homology among RNAs of avian leukosis-sarcoma viruses, reticuloendotheliosis viruses, and chicken endogenous RNA-directed DNA polymerase activity. Journal of Virology 12 1314-1324

Kang C-Y and Temin HM (1974) Reticuloendotheliosis virus nucleic acid sequences in cellular DNA. Journal of Virology 14 1179-1188

Kang DG, Moon MK, Choi DH, Lee JK, Kwon TO and Lee HS (2005) Vasodilatory and anti-inflammatory effects of the 1,2,3,4,6-penta-O-galloyl-beta-d-glucose (PGG) via a nitric oxide-cGMP pathway. European Journal of Pharmacology 524 111-119

Kang DG, Moon MK, Lee AS, Kwon TO, Kim JS and Lee HS (2007) Cornuside suppresses cytokine-induced proinflammatory and adhesion molecules in the human umbilical vein endothelial cells.
Biological & Pharmaceutical Bulletin 30 1796-1799

Kang DS, Kwon CH, Park JY, Kim JH, Woo JS, Jung JS and Kim YK (2006) 15-Deoxy-Delta(12,14)-prostaglandin J(2) induces renal epithelial cell death through NF-kB-dependent and MAPK-independent mechanism. Toxicology and Applied Pharmacology 216 426-435

Kang DW, Park MH, Lee YJ, Kim HS, Kwon TK, Park WS and Min DS (2008) Phorbol ester up-regulates phospholipase D1 but not phospholipase D2 expression through a PKC/ras/ERK/NFkB-dependent pathway and enhances matrix metalloproteinase-9 secretion in colon cancer cells. Journal of Biological Chemistry 283 4094-4104

Kang ES, Kim Gh, Kim HJ, Woo IS, Ham SA, Jin H, Kim MY, Kim HJ, Lee JH, Chang KC, Seo HG and Hwang JY (2008) Nrf2 regulates curcumin-induced aldose reductase expression indirectly via nuclear factor-kB. Pharmacology Research in press

Kang ES, Kim HJ, Paek KS, Jang HS, Chang KC, Lee JH, Nishinaka T, Yabe-Nishimura C and Seo HG (2005) Phorbol ester up-regulates aldose reductase expression in A549 cells: a potential role for aldose reductase in cell cycle modulation. Cell and Molecular Life Sciences 62 1146-1155

Kang G, Kong PJ, Yuh YJ, Lim SY, Yim SV, Chun W and Kim SS (2004) Curcumin suppresses lipopolysaccharide-induced cyclooxygenase-2 expression by inhibiting activator protein 1 and nuclear factor kB bindings in BV2 microglial cells. Journal of Pharmacological Sciences 94 325-328

Kang HB, Kim YE, Kwon HJ, Sok DE and Lee Y (2007) Enhancement of NF-kB expression and activity upon differentiation of human embryonic stem cell line SNUhES3. Stem Cells and Development 16 615-624

Kang J, Park EJ, Jou I, Kim JH and Joe EH (2001) Reactive oxygen species mediate A beta(25-35)-induced activation of BV- 2 microglia. Neuroreport 12 1449-1452

Kang JH, Kim CS, Han IS, Kawada T and Yu R (2007) Capsaicin, a spicy component of hot peppers, modulates adipokine gene expression and protein release from obese-mouse adipose tissues and isolated adipocytes, and suppresses the inflammatory responses of adipose tissue macrophages. FEBS Letters in press

Kang J-H, Sung M-K, Kawada T, Yoo H, Kim Y-K, Kim J-S and Yu R (2005) Soybean saponins suppress the release of proinflammatory mediators by LPS-stimulated peritoneal macrophages. Cancer Letters 230 219-227

Kang JL, Go YH, Hur KC and Castranova V (2000) Silica-induced nuclear factor-kB activation: involvement of reactive oxygen species and protein tyrosine kinase activation. Journal of Toxicology and Environmental Health 60 27-46

Kang JL, Jung HJ, Lee K and Kim HR (2006) Src tyrosine kinases mediate crystalline silica-induced NF-kB activation through tyrosine phosphorylation of IkB-a and p65 NF-kB in RAW 264.7 macrophages. Toxicological Sciences 90 470-477

Kang JL, Lee HS, Jung HJ and Kim HJ (2003) Iron tetrakis (N-methyl-4′-pyridyl) porphyrinato inhibits proliferative activity of thymocytes by blocking activation of p38 mitogen-activated protein kinase, nuclear factor-kB, and interleukin-2 secretion. Toxicology and Applied Pharmacology 191 147-155

Kang JL, Lee HS, Jung HJ, Kim HJ, Hah JS and Castranova V (2002) Inhibition of mitogenic stimulant-induced activation of thymocytes with zinc tetrakis-(N-methyl-4′-pyridyl) porphyrinato. Journal of Pharmacology and Experimental Therapeutics 303 1138-1144

Kang JL, Lee HW, Lee HS, Pack IS, Chong Y, Castranova V and Koh Y (2001)Genistein prevents nuclear factor-kB activation and acute lung injury induced by lipopolysaccharide. American Journal of Respiratory and Critical Care Medicine 164 2206-2212

Kang JL, Lee HS, Pack IS, Hur KC and Castranova V (2003) Phosphoinositide 3-kinase activity leads to silica-induced NF-kB activation through interacting with tyrosine-phosphorylated IkB-a and contributing to tyrosine phosphorylation of p65 NF-kB. Molecular and Cellular Biochemistry 248 17-24

Kang JL, Lee HS, Pack IS, Leonard S and Castranova V (2001) Iron tetrakis (n-methyl-4′-pyridyl) porphyrinato (FeTMPyP) is a potent scavenging antioxidant and an inhibitor of stimulant-induced NF-kB activation of raw 264.7 macrophages. Journal of Toxicology and Environmental Health 64 291-310

Kang JL, Lee HW, Kim HJ, Lee HS, Castrovnova V, Limm CM and Koh Y (2005) Inhibition of SRC tyrosine kinases suppresses activation of nuclear factor-kB, and serine and tyrosine phosphorylation of IkB-a in lipopolysaccharide-stimulated Raw 264.7 macrophages. Journal of Toxicology and Environmental Health 68 1643-1662

Kang JL, Pack IS, Hong SM, Lee HS, Castranova V (2000) Silica induces nuclear factor-kB activation through tyrosine phosphorylation of IkB-a in RAW264.7 macrophages. Toxicology and Applied Pharmacology 169 59- 65

Kang JL, Pack IS, Hong SM, Lee HS, Hah JS, Nam W, Leonard S and Castranova V (2001) Zinc tetrakis(N-methyl-4′-pyridyl) porphyrinato is an effective inhibitor of stimulant-induced activation of RAW 264.7 cells. Toxicology and Applied Pharmacology 172 140-149

Kang JL, Park W, Pack IS, Lee HS, Kim MJ, Lim CM and  Koh Y (2002) Inhaled nitric oxide attenuates acute lung injury via inhibition of nuclear factor-kB and inflammation. Journal of Applied Physiology 92 795-801

Kang JS, Jeon YJ, Park SK, Yang KH and Kim HM (2004) Protection against lipopolysaccharide-induced sepsis and inhibition of interleukin-1beta and prostaglandin E2 synthesis by silymarin. Biochemical Pharmacology 67 175-181

Kang JS, Jeon YJ, Suh J, Park SK, Yang KH and Kim HM (2004) 2-Acetylaminofluorene inhibits interleukin-1beta production in LPS-stimulated macrophages by blocking NF-kB/Rel activation. Cancer Letters 203 91-98

Kang JS, Park SK, Yang KH and Kim HM (2003) Silymarin inhibits TNF-alpha-induced expression of adhesion molecules in human umbilical vein endothelial cells. FEBS Letters 550 89-93

Kang JS, Yoon YD, Cho IJ, Han MH, Lee CW, Park SK and Kim HM (2004) Glabridin, an isoflavan from licorice root, inhibits inducible nitric oxide synthase expression and improves survival of mice in experimental model of septic shock. Journal of Pharmacology and Experimental Therapy 312 1187-1194

Kang JS, Yoon YD, Han MH, Han SB, Lee K, Kang MR, Moon EY, Jeon YJ, Park SK and Kim HM (2005) Estrogen receptor-independent inhibition of tumor necrosis factor-alpha gene expression by phytoestrogen equol is mediated by blocking nuclear factor-kB activation in mouse macrophages. Biochemical Pharmacology 71 136-143

Kang JS, Yoon YD, Han MH, Han SB, Lee K, Lee KH, Park SK and Kim HM (2006) Glabridin suppresses intercellular adhesion molecule-1 expression in TNF-a-stimulated human umbilical vein endothelial cells by blocking sphingosine kinase pathway: implications of Akt, ERK and NF-kB/Rel signaling pathways. Molecular Pharmacology 69 941-949

Kang JS, Yoon YD, Han MH, Han SB, Lee K, Park SK and Kim HM (2007) Equol inhibits nitric oxide production and inducible nitric oxide synthase gene expression through down-regulating the activation of Akt. International Immunopharmacology 7 491-499

Kang K, Kim H, Kim KI, Yang Y, Yoon DY, Kim JH, Ryu JH, Noh EJ, Jeon SD and Lim JS (2007) SK-126, a synthetic compound, regulates the production of inflammatory cytokines induced by LPS in antigen-presenting cells. Biochemical Pharmacology in press

Kang KA, Lee KH, Zhang R, Piao MJ, Kang MY, Kwak YS, Yoo BS, You HJ and Hung JW (2007) Protective effects of Castanopsis cuspidate through activation of ERK and NF-kB on oxidative cell death induced by hydrogen peroxide. Journal of Toxicology and Environmental Health A 70 1319-1328

Kang KN, Kim M, Pae KM and Lee ST (2002) Characterization of the 5′-flanking region of the human PTK6 gene. Biochimica et Biophysica Acta 1574 365-369

Kang KS, Kim HY, Yamabe N, Park JH and Yokozawa T (2007) Preventive effect of 20(S)-ginsenoside Rg(3) against lipopolysaccharide-induced hepatic and renal injury in rats. Free Radical Research 41 1181-1188

Kang KS, Yamabe N, Kim HY and Yokozawa T (2007) Effect of sun ginseng methanol extract on lipopolysaccharide-induced liver injury in rats. Phytomedicine in press

Kang KS, Yamabe N, Kim HY and Yokozawa T (2008) Role of maltol in advanced glycation end products and free radicals: in-vitro and in-vivo studies. J Pharm Pharmacol 60 445-452

Kang KW, Choi SY, Cho MK, Lee CH and Kim SG (2003) Thrombin induces nitric oxide synthase via Galpha 12/13-coupled PKC-dependent IkBa phosphorylation and JNK-mediated IkBa degradation. Journal of Biological Chemistry 278 17368-17378

Kang KW, Wagley Y, Kim HW, Pokharel YR, Chung YY, Chang IY, Kim JJ, Moon JS, Kim YK, HNah SY, Kang HS and Oh JW (2007) Novel role of IL-6/SIL-6R signaling in the expression of inducible nitric oxide synthase (iNOS) in murine B16, metastatic melanoma clone F10.9, cells. Free Radical Biology and Medicine 42 215-227

Kang L, McIntyre KW, Gillooly KM, Yang Y, Haycock J, Roberts S, Khanna A, Herpin TF, Yu G, Wu X, Morton GC, Tuerdi H, Koplowitz B, Walker SG, Wardwell-Swanson J, Macor JE, Lawrence RM and Carlson KE (2006) A selective small molecule agonist of the melanocortin-1 receptor inhibits lipopolysaccharide-induced cytokine accumulation and leukocyte infiltration in mice. Journal of Leukoctye Biology 80 897-904

Kang MH, So EY, Park H and Kim BS (2008) Replication of Theiler’s virus requires NF-kB-activation: higher viral replication and spreading in astrocytes from susceptible mice. Glia in press

Kang MK, Jhee EC, Koo BS, Yang JY, Park BH, Kim JS, Rho HW, Kim HR and Park JW (2002) Induction of nitric oxide synthase expression by Vibrio vulnificus cytolysin. Biochemical and Biophysica Research Communications 290 1090-1095

Kang MK, Yoon YE, Yang JY, Kwon KB, Park JW and Jhee EC (2004) Protective effect of retinoic acid on interleukin-1beta-induced cytotoxicity of pancreatic beta-cells. Mechanisms of Ageing & Development 125 483-490

Kang MW, Jang JY, Choi JY, Kim SH, Oh J, Cho BS and Lee CE (2008) Induction of IFN-g gene expression by thioredoxin: positive feed-back regulation of Th1 response by thioredoxin and IFN-g. Cellular Physiology and Biochemistry 21 215-224

Kang NY, Kang SK, Lee YC, Choi HJ, Lee YS, Cho SY, Kim YS, Ko JH and Kim CH (2006) Transcriptional regulation of the human GD3 synthase gene expression in Fas-induced Jurkat T cells: a critical role of transcription factor of NF-kB for regulated expression. Glycobiology 16 375-389

Kang NY, Kim CH, Kim KS, Ko JH, Lee JH, Jeong YK and Lee YC (2007) Expression of the human CMP-NeuAc:GM3 alpha2,8-sialyltransferase (GD3 synthase) gene through the NF-kB activation in human melanoma SK-MEL-2 cells. Biochimica et Biophysica Acta in press

Kang OH, Chae HS, Choi JH, Choi HJ, Park PS, Cho SH, Lee Gh, So HY, Choo YK, Kweon OH and Kwon DY (2006) Effects of the schisandra fructus water extract on cytokine release from a human mast cell line. Journal of Medicinal Food 9 480-486

Kang OH, Choi YA, Park HJ, Kang CS, Song BS, Choi SC, Nah YH, Yun KJ, Cai XF, Kim YH, Bae KH and Lee YM (2006) Inhibition of trypsin-induced mast cell activation by acanthoic acid. Journal of Ethnopharmacology 10-5 326-331

Kang OH, Kim JA, Choi YA, Park HJ, Kim DK, An YH, Choi SC, Yun KJ, Nah YH, Cai XF, Kim YH, Bae KH and Lee YM (2005) Inhibition of interleukin-8 production in the human colonic epithelial cell line HT-29 by 18beta-glycyrrhetinic acid. International Journal of Molecular Medicine 15 981-985

Kang OH, Lee GH, Choi HJ, Park PS, Chae HS, Jeong SI, Kim YC, Sohn DH, Park H, Lee JH and Kwon DY (2007) Ethyl acetate extract from Angelica Dahuricae Radix inhibits lipopolysaccharide-induced production of nitric oxide, prostaglandin E(2) and tumor necrosis factor-alphavia mitogen-activated protein kinases and nuclear factor-kB in macrophages. Pharmacological Research 55 263-270

Kang S, Kim YB, Kim MH, Yoon KS, Kim JW, Park NH, Song YS, Kang D, Yoo KY, Kang SB and Lee HP (2005) Polymorphism in the nuclear factor kappa-B binding promoter region of cyclooxygenase-2 is associated with an increased risk of bladder cancer. Cancer Letters 217 11-16

Kang S-M, Tran A-C, Grilli M and Lenardo MJ (1992) NF-kB subunit regulation in nontransformed CD4+ T lymphocytes. Science 256 1452-1456

Kang SN, Kim SH, Chung SW, Lee MH, Kim HJ and Kim TS (2002) Enhancement of 1 alpha,25-dihydroxyvitamin D(3)-induced differentiation of human leukaemia HL-60 cells into monocytes by parthenolide via inhibition of NF-kB activity. British Journal of Pharmacology 135 1235-1244

Kang SS, Cuendet M, Endringer DC, Croy VL, Pezzuto JM and Lipton MA (2008) Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-kB. Biorganic Medicinal Chemistry in press

Kang SS, Woo SS, Kim J, Yang JS, Yun CH, Ju HR, Son CG, Moon EY and Han SH (2007) Human placenta promotes IL-8 expression through activation of JNK/SAPK and transcription factors NF-kB and AP-1 in PMA-differentiated THP-1 cells.International Immunopharmacology 7 1488-1495

Kang W, Saito H, Fukatsu K, Nagawa H and Ikeda S (2003) Brief refeeding rapidly reverses dietary restriction-induced nuclear factor-kappaB downregulation in peritoneal resident cells. JPEN J Parenter Enteral Nutr 27 193-197

Kang YH, Lee KA, Ryu CJ, Lee HG, Lim JS, Park SN, Paik SG and Yoon DY (2006) Mitomycin C induces apoptosis via Fas/FasL dependent pathway and suppression of IL-18 in cervical carcinoma cells. Cancer Letters i237 33-44

Kang YH, Lee KA, Yang Y, Kim SH, Kim JH, Park SN, Paik SG and Yoon DY (2007) The apoptotic effect of intercalating agents on HPV-negative cervical cancer C-33A cells. Amino Acids in press

Kang YJ, Chen J, Otsuka M, Mols J, Ren S, Wang Y and Han J (2008) Macrophage deletion of p38alpha partially impairs lipopolysaccharide-induced cellular activation. Journal of Immunology 180 5075-5082

Kang YJ, Kim SO, Shimada S, Otsuka M, Seit-Nebi A, Kwon BS, Watts Th and Han J (2007) Cell surface 4-1BBL mediates sequential signaling pathways ‘downstream’ of TLR and is required for sustained TNF production in macrophages. Nature Immunology  in press

Kang YJ, Kusler B, Otsuka M, Hughes M, Suzuki N, Suzuki S, Yeh WC, AKira S, Han J and Jones PP (2007) Calcineurin negatively regulates TLR-mediated activation pathways. Journal of Immunology 179 4598-4607

Kang YJ, Lee YS, Lee GW, Lee DH, Ryu JC, Yun-Choi HS and Chang KC (1999) Inhibition of activation of nuclear factor kappaB is responsible for inhibition of inducible nitric oxide synthase expression by higenamine, an active component of aconite root. Journal of Pharmacology and Experimental Therapy 291 314-320

Kang YJ, Lee BK, Lee YS, Seo HG, Park MK, Kim HJ, Pyo HS, Chong WS, Jung HJ, Yun-Choi HS, Lee DH and Chang KC (2003) Suppression of tumor necrosis factor-a and inducible nitric oxide synthase gene expression by THI 52, a new synthetic naphthyl-benzylisoquinoline alkaloid. Biochemical Pharmacology 65 457-464

Kang YJ, Wingerd BA, Arakawa T and Smith WL (2006) Cyclooxygenase-2 gene transcription in a macrophage model of inflammation. Journal of Immunology 177 8111-8122

Kang YM, Kim SY, Kang JH, Han SW, Nam EJ, Kyung HS, Park JY and Kim IS (2007) Light up-regulated on B lymphocytes and monocytes in rheumatoid arthritis mediates cellular adhesion and metalloproteinase production by synoviocytes. Arthritis andRheumatism 56 1106-1111

Kang YM, Ma Y, Elks C, Zhang JP, Yang ZM and Francis J (2008) Cross talk between cytokines and renin-angiotensin in hypothalamic paraventricular nucleus in heart failure: role of nuclear factor-kB. Cardiovascular Research in press

Kania J, Baranska A and Guzdek A (2003) Cytokine action and oxidative stress response in differentiated neuroblastoma SH-SY5Y cells. Acta Biochim Pol 50 659-666

Kaniowskia D, Kaminski R, Amini S, Radhakrishnan S, Rappaport J, Johnson E, Khalili K, Del Valle L and Darbinyan A (2006) Cross-interaction between JC virus agnoprotein and human immunodeficiency virus type 1 (HIV-1) Tat modulates transcription of the HIV-1 long terminal repeat in glial cells. Journal of Virology 80 9288-9299

Kanke T, Takizawa T, Kabeya M and Kawabata A (2005) Physiology and pathophysiology of proteinase-activated receptors (PARs): PAR-2 as a potential therapeutic target. Journal of Pharmacological Science 97 38-42

Kankova K, Vojtesek B and Valik D (2001) The Rel/NF-kB transcription factors and their biological functions [Article in Czech]. Cas Lek Cesk 140 163-167

Kannan-Thulasiraman P and Shapiro DJ (2002) Modulators of inflammation use NF-kB and AP-1 sites to induce the caspase-1 and granzyme B inhibitor, proteinase inhibitor 9. Journal of Biological Chemistry 277 41230-41239

Kanneganti TD, Lamkanfi M and Nunez G (2007) Intracellular NOD-like receptors in host defense and disease. Immunity 27 549-559

Kanneganti TD, Ozoren N, Body-Malapel M, Amer A, Park JH, Franchi L, Whitfield J, Barchet W, Colonna M, Vandenabeele P, Bertin J, Coyle A, Grant EP, AKira S and Nunez G (2006) Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 233-236

Kanning KC, Hudson M, Amieux PS, Wiley JC, Bothwell M and Schecterson LC (2003) Proteolytic processing of the p75 neurotrophin receptor and two homologs generates C-terminal fragments with signaling capability. Journal of Neuroscience 23 5425-5436

Kanno S, Hiura T, Shouji A, Osani Y, Ujibe M and Ishikawa M (2007) Resistance to Ara-C up-regulates the activation of NF-kB, telomerase activity and Fas expression in NALM-6 cells. Biol Pharm Bulletin 30 2069-2974

Kanno SI, Shouji A, Tomizawa A, Hiura T, Osanai Y, Ujibe M, Obara Y, Nakahata N and Ishikawa M (2005) Inhibitory effect of naringin on lipopolysaccharide (LPS)-induced endotoxin shock in mice and nitric oxide production in RAW 264.7 macrophages. Life Sciences 78 673-681

Kanno SI, Tomizawa A, Ohtake T, Koiwai K, Ujibe M and Ishikawa M (2006) Naringenin-induced apoptosis via activation of NF-kB and necrosis involving the loss of ATP in human promyeloleukemia HL-60 cells. Toxicology Letters 166 131-139

Kanno T and Siebenlist U (1996) Activation of nuclear factor kB via T cell receptor requires a Raf kinase and Ca2+ influx. Journal of Immunology 157 5277-5283

Kanno T, Brown K and Siebenlist U (1995) Evidence in support of a role for HTLV-I Tax in activating NF-kB via stimulation of signaling pathways. Journal of Biological Chemistry 270 11745-11748

Kanno T, Brown K, Franzoso G and Siebenlist U (1994) Kinetic analysis of human T-cell leukemia virus type-I Tax-mediated activation of NF-kB. Molecular and Cellular Biology 14 6443-6451

Kanno T, Franzoso G and Siebenlist U (1994) Human T-cell leukemia virus type I Tax protein-mediated activation of NF-kB from p100 (NF-kB2)-inhibited cytoplasmic reserves. Proceedings of the National Academy of Sciences USA 91 12634-12638

Kantengwa S, Jornot L, Devenoges C and Nicod LP (2003) Superoxide anions induce the maturation of human dendritic cells. American Journal of Respiratory and Critical Care Medicine 167 431-437

Kanters E, Gijbels MJ, Van Der Made I, Vergouwe MN, Heeringa P, Kraal G, Hofker MH and De Winther MP (2003) Hematopoietic NF-kB1 deficiency results in smaller atherosclerotic lesions with a more inflammatory phenotype. Blood 103 934-940

Kanters E, Pasparakis M, Gijbels MJ, Vergouwe MN, Partouns-Hendriks I, Fijneman RJ, Clausen BE, Forster I, Kockx MM, Rajewsky K, Kraal G, Hofker MH and De Winther MP (2003) Inhibition of NF-kB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice. Journal of Clinical Investigation 112 1176-1185

Kanthasamy A, Kitazawa M, Kaul S, Anantharam V and Kanthasamy AG (2002) A novel oxidative stress dependent apoptotic pathway in pesticide-induced dopaminergic degeneration in PD models. Journal of Neurochemistry 81 76

Kanzaki H, Chiba M, Shimizu Y and Mitani H (2001) Dual regulation of osteoclast differentiation by periodontal ligament cells through RANKL stimulation and OPG inhibition. Journal of Dental Research 80 887-891

Kanzawa N, Nishigaki K, Hayashi T, Ishii Y, Furukawa S, Niiro A< yasui F, Kohara M, Morita K, Matsushima K, Le MQ, Masuda T and Kannagi M (2006) Augmentation of chemokine production by severe acute respiratory syndrome coronavirus 3a/X1 and 7a/X4 proteins through NF-kB activation. FEBS Letters 580 6807-6812

Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW and Wu R (2004) IL-17 markedly up-regulates b-defensin-2 expression in human airway epithelium via JAK and NF-kB signaling pathways. Journal of Immunology 173 3482-3491

Kao CY, Huang F, Chen Y, Thai P, Wachi S, Kim C, Tam L and Wu R (2005) Up-regulation of CC chemokine ligand 20 expression in human airway epithelium by IL-17 through a JAK-independent but MEK/NF-kB-dependent signaling pathway. Journal of Immunology 175 6676-6685

Kao CY, Kim C, Huang F and Wu R (2008) Requirements for two proximal NF-kB binding sites and IkB-z in IL-17A-induced human beta -defensin 2 expression by conducting airway epithelium. Journal of Biological Chemistry in press

Kao ES, Wang CJ, Lin WL, Chu CY and Tseng TH (2007) Effects of polyphenols derived from fruit of Crataegus pinnatifida on cell transformation, dermal edema and skin tumor formation by phorbol ester application. Food and Chemical Toxicology in press

Kao JJ (2006) The NF-kB inhibitor pyrrolidine dithiocarbamate blocks IL-1beta induced hyaluronan synthase 1 (HAS1) mRNA transcription, pointing at NF-kB dependence of the gene HAS1. Experimental Gerontology 41 641-647

Kao JY, Pierzchala A, Rathinavelu S, Zavros Y, Tessier A, and Merchant JL (2005) Somatostatin inhibits dendritic cell responsiveness to Helicobacter pylori.Regulatory Peptides 134 23-29

Kao KR and Hopwood ND (1991) Expression of a mRNA related to c-rel and dorsal in early Xenopus laevis embryos. Proceedings of the National Academy of Sciences USA 88 2697-2701

Kao KR and Lockwood A (1996) Negative regulation of dorsal patterning in early embryos by overexpression of XrelA, a Xenopus homologue of NF-kB. Mechanisms of Development 58 129-139

Kao SJ, Lei HC, Kuo CT, Chang MS, Chen BC, Chang YC, Chiu WT and Lin CH (2005) Lipoteichoic acid induces nuclear factor-kappaB activation and nitric oxide synthase expression via phosphatidylinositol 3-kinase, Akt, and p38 MAPK in RAW 264.7 macrophages. Immunology 115 366-374

Kao YH, Goto S, Jawan B, Nakano T, Hsu LW, Lin YC, Pan MC, Lai CY, Sun CK, Cheng YF, Tai MH, Huang HT and Chen CL (2007) Heat preconditioning ameliorates hepatocyte viability after cold preservation and rewarming, and modulates its immunoactivity. Transplantation Immunology 18 220-231

Kao YS and Fong JC (2008) Endothelin-1 induces glut1 transcription through enhanced interaction between Sp1 and NF-kB transcription factors. Cellular Signaling in press

Kapahi P, Takahashi T, Natoli G, Adams SR, Chen Y, Tsien RY and Karin M (2000) Inhibition of NF-kB activation by arsenite through reaction with a critical cysteine in the activation loop of IkB kinase. Journal of Biological Chemistry 275 36062-36066

Kapalla M, Yeghiazaryan K, Hricova M, Moenkemann H, Pirek A, Schild HH and Golubnitschaja O (2005) Combined analysis of biochemical parameters in serum and differential gene expression in circulating leukocytes may serve as an ex vivo monitoring system to estimate risk factors for complications in Diabetes mellitus. Amino Acids 28 221-227

Kapasi AA, Fan S and Singhal PC (2006) Scatter factor mitigates HIV-1 gp120-induced human mesangial cell injury. Nephron and Experimental Nephrology 103 e103-e108

Kapetanovic R, Nahori MA, Balloy V, Fitting C, Philpott DJ, Cavaillon JM and Adib-COnquy M (2006) Contribution of phagocytosis and intracellular sensing for cytokine production by Staphylococcus aureus-activated macrophages. Infection and Immunity in press

Kaplan BL, Ouyang Y, Herring A, Su Yea S, Razdan R and Kaminski NE (2005) Inhibition of leukocyte function and interleukin-2 gene expression by 2-methylarachidonyl-(2′-fluoroethyl)amide, a stable congener of the endogenous cannabinoid receptor ligand anandamide. Toxicology and Applied Pharmacology 205 107-115

Kaplan JM, Cook JA, Hake PW, O’Connor M, Burroughs TJ and Zingarelli B (2005) 15-deoxy-delta12,14-prostaglandin J2 (15D-PJG2), a peroxisome proliferator activated receptor gamma ligand, reduces tissue leukosequestration and mortality in endotoxic shock. Shock 24 59-65

Kapoor GS, Zhan Y, Johnson GR and O’Rourke DM (2004) Distinct domains in the SHP-2 phosphatase differentially regulate epidermal growth factor receptor/NF-kB activation through Gab1 in glioblastoma cells. Molecular and Cellular Biology 24 823-836

Kappler C, Meister M, Lagueux M, Gateff E, Hoffmann JA and Reichhart JM (1993) Insect Immunity. Two 17 bp repeats nesting a kB-related sequence confer inducibility to the diptericin gene and bind a polypeptide in bacteria-challenged Drosophila. EMBO Journal 12 1561-1568

Karacay B, Sanlioglu S, Griffith TS, Sandler A and Bonthius DJ (2004) Inhibition of the NF-kB pathway enhances TRAIL-mediated apoptosis in neuroblastoma cells. Cancer Gene Therapy 11 681-690

Karadag A, Zhou M and Croucher PI (2006) ADAM-9 (mdc-9/meltrin-{gamma}), a member of the a disintegrin and metalloproteinase family, regulates myeloma cell induced interleukin-6 production in osteoblasts by direct interaction with the {alpha}v{beta}5-integrin. Blood 107 3271-3278

Karagiannides I, Kokkotou E, Tansky M, Tchkonia T, Giorgadze N, O’Brien M, Leeman SE, Kirkland JL and Pothoulakis C (2006) Induction of colitis causes inflammatory responses in fat depots: evidence for substance P pathways in human mesenteric preadipocytes. Proceedings of the National Academy of Sciences USA 103 5207-5212

Karalis KP, Venihaki M, Zhao J, Van Vlerken LE and Chandras C (2004) Nuclear factor-kB participates in the corticotropin releasing hormone-induced regulation of the pituitary proopiomelanocortin gene. Journal of Biological Chemistry 279 10837-10840

Karamenderes C, Konyalioglu S, Khan S and Khan IA (2007) Total phenolic contents, free radical scavenging activities and inhibitory effects on the activation of NF-kB of eight Centaurea L. species. Phytotherapy Research in press

Karashima T, Sweeney P, Kamat A, Huang S, Kim SJ, Bar-Eli M, McConkey DJ and Dinney CP (2003) Nuclear Factor-kB mediates angiogenesis and metastasis of human bladder cancer through the regulation of interleukin-8. Clinical Cancer Research 9 2786-2797

Karatsaidis A, Hayashi K, Schreurs O, Helgeland K and Schenck K (2007) Survival signalling in keratinocytes of erythematous oral lichen planus. Journal of Oral Pathology and Medicine 36 215-222

Karayiannis P (2005) The hepatitis C virus NS3/4A protease complex interferes with pathways of the innate immune response. Journal of Hepatology 43 743-745

Karban A, Okazaki T, Panhuysen CI, Gallegos T, Potter JJ, Bailey-Wilson JE, Silverberg MS, Duerr RH, Cho J, Gregersen PK, Wu Y, Achkar JP, Dassopoulos T, Mezey E, Bayless TM, Nouvet FJ and Brant SR (2004) Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis. Human Molecular Genetics 13 35-45

Kariko K, Ni H, Capodici J, Lamphier M and Weissman D (2004) mRNA is an endogenous ligand for toll-like receptor 3. Journal of Biological Chemistry 279 12542-12550

Karimi K, Sarir H, Mortaz E, SMit JJ, Hosseini H, de Kimpe S, Nijkamp F and Folkerts G (2006) Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages Respiratory Research 7 66

Karimipour DJ, Kang S, Johnson TM, Orringer JS, Hamilton T, Hammerberg C, Voorhees JJ and Fisher G (2005) Microdermabrasion: A molecular analysis following a single treatment. Journal of the American Academy of Dermatology 52 215-223

Karin M (1991) Signal transduction and gene control. Current Opinion in Cell Biology 3 467-473

Karin M (1998) The NF-kB activation pathway: its regulation and role inflammation and cell survival. Cancer Journal of Scientific American 4 S92-S99

Karin M (1999) The beginning of the end: IkB kinase (IKK) and NF-kB activation. Journal of Biological Chemistry 274 27339-27342

Karin M (2004) Mitogen activated protein kinases as targets for development of novel anti-inflammatory drugs. Annals of Rheumatoid Disease Suppl 2 ii62-ii64

Karin M (2005) Inflammation-activated protein kinases as targets for drug development. Proceedings of the American Thoracic Society 2 386-390

Karin M (2006) NF-kB and cancer: Mechanisms and targets. Molecular Carcinogenesis 45 355-361

Karin M (2006) Nuclear factor-kB in cancer development and progression. Nature 441431-436

Karin M (2006) Role for IKK2 in muscle: waste not, want not. Journal of Clinical Investigation 116 2866-2868

Karin M (2008) The IkB kinase – a bridge between inflammation and cancer. Cell Research in press

Karin M and Delhase M (1998) JNK or IKK, AP-1 or NF-kB, which are the targets for MEK kinase 1 action. Proceedings of the National Academy of Sciences USA 95 9067-9069

Karin M and Delhase M (2000) The IkB kinase (IKK) and NF-kB: key elements of proinflammatory signalling. Seminars in Immunology 12 85-98

Karin M and Greten FR (2005) NF-kB: linking inflammation and immunity to cancer development and progression. Nature Reviews Immunology 5 749-759

Karin M and Hunter T (1995) Transcriptional control by protein phosphorylation: signal transmission from the cell surface. Current Biology 5 747-757

Karin M and Lin A (2002) NF-kB at the crossroads of life and death. Nature Immunology 3 221-227

Karin M, Cao Y, Greten FR and Li ZW (2002) NF-kB incancer: from innocent bystander to major culprit. Nature Reviews on Cancer 2 301-310

Karin M and Lin A (2002) NF-kB at the crossroads of life and death. Nature Immunology 3 221-227

Karin M, Takahashi T, Kapahi P, Delhase M, Chen Y, Makris C, Rothwarf D, Baud V, Natoli G, Guido F and Li N (2001) Oxidative stress and gene expression: The AP-1 and NF-kB connections. Biofactors 15 87-89

Karin M, Yamamoto Y and Wang QM (2004) The IKK NF-kB system: a treasure trove for drug development. Nature Reviews Drug Discovery 3 17-26

Karl E, Warner K, Zeitlin B, Kaneko T, Wurtzel L, Jin T, Chang J, Wang S, Wang CY, Strieter RM, Nunez G, Polverini PJ and Nor JE (2005) Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kB and CXC chemokines. Cancer Research 65 5063-5069

Karlsen A, Retterstol L, Laake P, Paur I, Kjolsrud-Bohn S, Sandvik L and Blomhoff R (2007) Anthocyanins inhibit nuclear factor-kB activation in monocytes and reduce plasma concentrations of pro-inflammatory mediators in healthy adults. Journal of Nutrition 137 1951-1954

Karlsen AE, Heding PE, Frobose H, Ronn SG, Kruhoffer M, Orntoft TF, Darville M, Eizirik DL, Pociot F, Nerup J, Mandrup-Poulsen T and Billestrup N (2004) Suppressor of cytokine signalling (SOCS)-3 protects beta cells against IL-1beta-mediated toxicity through inhibition of multiple nuclear factor-kB-regulated proapoptotic pathways. Diabetologia 47 1998-2011

Karmakar S, Banik NL and Ray SK (2007) Combination of all-trans retinoic acid and paclitaxel-induced differentiation and apoptosis in human glioblastoma U87MG xenografts in nude mice. Cancer in press

Karna E, Miltyk W, Surazynski A and Palka JA (2007) Protective effect of hyaluronic acid on interleukin-1-induced deregulation of beta(1)-integrin and insulin-like growth factor-I receptor signaling and collagen biosynthesis in cultured human chondrocytes.
Molecular and Cellular Biochemistry in press

Karnoub AE, Der CJ and Campbell SL (2001) The insert region of Rac1 is essential for membrane ruffling but not cellular transformation. Molecular and Cellular Biology 21 2847-2857
Karrasch T and Jobin C (2007) NF-kB and the intestine: friend or foe? InflammatoryBowel Disease in press

Karrasch T, Kim JS, Jang BI and Jobin C (2007) The flavonoid luteolin worsens chemical-induced colitis in NF-kB transgenic mice through blockade of NF-kB-dependent protective molecules. PLoS ONE 2 e596

Karrasch T, Kim JS, Muhlbauer M, Magness St and Jobin C (2007) Gnotobiotic IL-10-/-;NF-kBEGFP mice reveal the critical role of TLR/NF-kB signaling in commensal bacteria-induced colitis. Journal of Immunology 178 6522-6532

Karrasch T, Steinbrecher KA, Allard B, Baldwin AS and Jobin C (2006) Wound-induced p38MAPK-dependent histone H3 phosphorylation correlates with increased COX-2 expression in enterocytes. Journal of Cellular Physiology 207 809-815

Kasahara DI,Poynter ME, Othman Z< Hemenway D and van Der Vliet A (2008) Acrolein inhalation suppresses lipopolysaccharide-induced inflammatory cytokine production but does not affect acute airways neutrophilia. Journal of Immunology 181 736-745

Kasai T, Miyauchi K, Yokoyama T, Kojimoto K, Sumiyoshi K, Kubota N, Ikeda E and Daida H (2008) Pioglitazone attenuates neointimal thickening via suppression of the early inflammatory response in a porcine coronary after stenting. Atherosclerosis197 612-619

Kase H, Hattori Y, Jojima T, Okayasu T, Tomizawa A, Suzuki K, Banba N, Monden T, Satoh H, Akimoto K and Kasai K (2007) Globular adiponectin induces adhesion molecule expression through the sphingosine kinase pathway in vascular endothelial cells.Life Sciences 81 939-943

Kase S, Aoki K, Harada T, Harada C, Ohgami K, Shiratori K, Nishi S, Ohno S and Yoshida K (2004) Activation of nuclear factor-kB in the conjunctiva with the epithelial scraping of the mouse cornea and human epidemic keratoconjunctivitis. British Journal of Ophthalmology 88 947-949

Kashanchi F and Brady JN (2005) Transcriptional and post-transcriptional gene regulation of HTLV-1. Oncogene 24 5938-5951

Kashani-Sabet M, Liu Y, Fong S, Desprez PY, Liu S, Tu G, Nosrati M, Handumrongkul C, Liggitt D, Thor AD and Debs RJ (2002) Identification of gene function and functional pathways by systemic plasmid-based ribozyme targeting in adult mice. Proceedings of the National Academy of Sciences USA 99 3878-3883

Kashani-Sabet M, Shaikh L, Miller JR 3rd, Nosrati M, Ferreira CM, Debs RJ and Sagebiel RW (2004) NF-kB in the vascular progression of melanoma. Journal of Clinical Oncology 22 617-623

Kashfi K and Rigas B (2005) Molecular targets of nitric-oxide-donating aspirin in cancer. Biochemistry Society Transactions 33 701-714

Kashiwase K, Higuchi Y, Hirotani S, Yamaguchi O, Hikoso S, Takeda T, Watanabe T, Taniike M, Nakai A, Tsujimoto I, Matsumura Y, Ueno H, Nishida K, Hori M and Otsu K (2004) CaMKII activates ASK1 and NF-kB to induce cardiomyocyte hypertrophy. Biochemical and Biophysical Research Communications 327 136-142

Kasibhatla S, Brunner T, Genestier L, Echeverri F, Mahboubi A and Green DR (1998) DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kB and AP-1. Molecular Cell 1 543-551

Kasibhatla S, Genestier L and Green DR (1999) Regulation of Fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kB. Journal of Biological Chemistry 274 987-992

Kasinski AI, Du Y, Thomas SI, Zhao J, Sun S-Y, Khuri FR, Wang C-Y, Shoji M, Sun A, Snyder JP, Liotta D and Fu H (2008) Inhibition of IKK-NF-kB signaling pathway by EF24,a novel monoketone analogue of curcumin. Molecular Pharmacology in press

Kasof GM, Lu JJ, Liu D, Speer B, Mongan KN, Gomes BC and Lorenzi MV (2001) Tumor Necrosis Factor-a induces expression of DR6, a member of the TNF receptor family, through activation of NF-kB. Oncogene 20 7965-7975

Kasperczyk H, La Ferla-Bruhl K, Westhoff MA, Behrend L, Zwacka RM, Debatin KM and Fulda S (2005) Betulinic acid as new activator of NF-kB: molecular mechanisms and implications for cancer therapy. Oncogene 24 6945-6956

Kasravi F, Lee DH and Harris HW (2003) Chylomicron-bound LPS selectively inhibits the TNF-alpha signaling pathway in rat hepatocytes. Journal of Surgical Research 114 287

Kassardjian A and Kreydyyeh SI (2008) JNK modulates the effect of caspases and NF-kB in the TNF-a-induced down-regulation of Na(+)/K(+)ATPase in HepG2 cells. Journal of Cellular Physiology in press

Kassed C, Willing A, Garbuzova-Davis S, Sanberg P and Pennypacker K (2002) Lack of NF-kB p50 exacerbates degeneration of hippocampal neurons after chemical exposure and impairs learning. Experimental Neurology 176 277-288

Kassed CA, Butler TL, Navidomskis MT, Gordon MN, Morgan D and Pennypacker KR (2003) Mice expressing human mutant presenilin-1 exhibit decreased activation of NF-kB p50 in hippocampal neurons after injury. Brain Research Molecular Brain Research 110 152-157

Kassed CA, Butler TL, Patton GW, De Mesquita DD, Navidomskis MT, Memet S, Israel A and Pennypacker KR (2004) Injury-induced NF-kB activation in the hippocampus: implications for neuronal survival.
FASEB Journal 18 723-734

Kassed CA and Herkenham M (2004) NF-kappaB p50-deficient mice show reduced anxiety-like behaviors in tests of exploratory drive and anxiety. Behavior Brain Research 154 577-584

Kassel O, Schneider S, Heilbock C, Litfin M, Gottlicher M and Herrlich P (2004) A nuclear isoform of the focal adhesion LIM-domain protein Trip6 integrates activating and repressing signals at AP-1- and NF-kB-regulated promoters. Genes & Development 18 2518-2528

Kast RE (2005) Evidence of a mechanism by which etanercept increased TNF-alpha in multiple myeloma: New insights into the biology of TNF-alpha giving new treatment opportunities-the role of bupropion. Leukemia Research 29 1459-1463

Kast RE (2006) Aspirin, TNF-a, NFkB, and survival in multiple myeloma: the importance of measuring TNF-a. Inflammopharmacology in press

Kastenbauer S, Koedel U, Weih F, Ziegler-Heitbrock L and Pfister HW (2004) Protective role of NF-kB1 (p50) in experimental pneumococcal meningitis. Circulation European Journal of Pharmacology 498 315-318

Kastl SP, Speidl WS, Kaun C, Rega G, Assadian A, Weiss TW, Valent P, Hagmueller GW, Maurer G, Huber K and Wojita J (2006) The complement component C5a induces the expression of plasminogen activator inhibitor-1 in human macrophages via NF-kB activation. Journal of Thrombosis and Haemostosis 4 1790-1797

Kastner DL (2005) Hereditary periodic Fever syndromes. Hematology (American Society of Hematology Education Program) 74-81

Kasuga C, Ebata T, Kayagaki N, Yagita H, Hishii M, Arai H, Sato Ka nd Okumura K (2004) Sensitization of human glioblastomas to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by NF-kB inhibitors. Cancer Science 95 840-844

Kasza A, Kiss DL, Gopalan S, Xu W, Rydel RE, Koj A and Kordula T (2002) Mechanism of plasminogen activator inhibitor-1 regulation by oncostatin M and interleukin-1 in human astrocytes. Journal of Neurochemistry 83 696-703

Kaszkin M, Beck KF, Koch E, Erdelmeier C, Kusch S, Pfeilschifter J and Loew D (2004) Downregulation of iNOS expression in rat mesangial cells by special extracts of Harpagophytum procumbens derives from harpagoside-dependent and independent effects. Phytomedicine 11 585-595

Kaszubska W, Hooft van Huijsduijnen R, Ghersa P, DeRaemy-Schenk A-M, Chen BPC, Hai T, DeLamarter JF and Whelan J (1993) Cyclic AMP-independent ATF family members interact with NF-kB and function in the activation of the E-selectin promoter in response to cytokines. Molecular and Cellular Biology 13 7180-7190

Katafuchi T, Kondo T, Take S and Yoshimura M (2005) Enhanced expression of brain interferon-alpha and serotonin transporter in immunologically induced fatigue in rats. European Journal of Neuroscience 22 2817-2826

Katafuchi T, Takaki A, Take S, Kondo T and Yoshimura M (2003) Endotoxin inhibitor blocks heat exposure-induced expression of brain cytokine mRNA in aged rats. Brain Research Molecular Brain Research 118 24-32

Katagiri D, Hayashi H, Victoriano AF, Okamoto T  and Onozaki K (2006) Estrogen stimulates transcription of human immunodeficiency virus type 1 (HIV-1).International Immunopharmacology 6 170-181

Katagiri T and Takahashi N (2002) Regulatory mechanisms of osteoblast and osteoclast differentiation. Oral Disease 8 147-159

Katakai T, Hara T, Sugai M, Gonda H and Shimizu A (2004) Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytes. Journal of Experimental Medicine 200 783-795

Katano H, Pesnicak L and Cohen JI (2004) Simvastatin induces apoptosis of Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines and delays development of EBV lymphomas. Proceedings of the National Academy of Sciences USA 101 4960-4965

Kataoka T, Budd RC, Holler N, Thome M, Martinon F, Irmler M, Burns K, Hahne M, Kennedy N, Kovacsovics M, Tschopp J (2000) The caspase-8 inhibitor FLIP promotes activation of NF-kB and Erk signaling pathways. Current Biology 10 640-648

Kataoka Y, Murley JS, Khodarev NN, Weichselbaum RR and Grdina DJ (2002) Activation of the nuclear transcription factor kB (NFkB) and differential gene expressionin U87 glioma cells after exposure to the cytoprotector amifostine. Int J Radiat Oncol Biol Phys 53 180-189

Kataoka T and Tschopp J (2004) N-Terminal Fragment of c-FLIP(L) Processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kB signaling pathway. Molecular and Cellular Biology 24 2627-2636

Katarina K, Daniela P, Peter N, Marianna R, Pavlina C, Stepanka P, Jan L, Ludmila T, Michal A and Marie C (2007) HLA, NFKB1 and NFKBIA gene polymorphism profile in autoimmune diabetes mellitus patients. Experimental and Clinical Endocrinology & Diabetes 115 124-129

Katdare M, Efimova EV, Labay E, Khodarev NN, Darga TE, Garofalo M, Nakamura S, Kufe DW, Posner MC and Weichselbaum RR (2007) Diverse TNFa-induced death pathways are enhanced by inhibition of NF-kB. International Journal of Oncology 31 1519-1528

Katerinaki E, Haycock JW, Lalla R, Carlson KE, Yang Y, Hill RP, Lorigan PC and MacNeil S (2006) Sodium salicylate inhibits TNF-a-induced NF-kB activation, cell migration, invasion and ICAM-1 expression in human melanoma cells. Melanoma Research16 11-22

Katiyar SK (2008) Grape seed proanthocyanidines and skin cancer prevention: Inhibition of oxidative stress and protection of immune system. Molecular Nutrition and Food Research 52 S71-S76

Katiyar SK and Meeran SM (2007) Obesity increases the risk of UV radiation-induced oxidative stress and activation of MAPK and NF-kB signaling. Free Radical Biology and Medicine 42 299-310

Kato A, Edwards MJ and Lentsch AB (2002) Gene deletion of NF-kB p50 does not alter the hepatic inflammatory response to ischemia/reperfusion. Journal of Hepatology 37 48-55

Kato A, Favoreto Jr S, Avila PC and Schleimer RP (2007) TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells. Journal of Immunology 179 1080-1087

Kato A, Homma T, Batchelor J, Hashimoto N, Imai S, Wakiguchi H, Saito H and Matsumoto K (2003) Interferon-a/b receptor-mediated selective induction of a gene cluster by CpG oligodeoxynucleotide 2006. BMC Immunology 4 8

Kato A, Ogasawara T, Homma T, Batchelor J, Imai S, Wakiguchi H, Saito H and Matsumoto K (2004) CpG oligodeoxynucleotides directly induce CXCR3 chemokines in human B cells. Biochemical and Biophysical Research Communications 320 1139-1147

Kato A, Ogasawara T, Homma T, Saito H and Matsumoto K (2004) Lipopolysaccharide-binding protein critically regulates lipopolysaccharide-induced IFN-beta signaling pathway in human monocytes. Journal of Immunology 172 6185-6194

Kato I, Oya T, Suzuki H, Takasawa K, Ichsan AM, Nakada S, Ishiii Y, Shimada Y, Sasahara M, Tobe K, Takasawa S, Okamoto H and Hiraga K (2008) A novel model of insulin-dependent diabetes with renal and retinal lesions by transgenic expression of CaMKIIalpha (Thr286Asp) in pancreatic beta-cells. Diabetes and Metabolism Research Reviews in press

Kato N, Motohashi S, Okada T, Ozawa T and Mashima K (2008) PICOT, protein kinase C theta-interacting protein, is a novel regulator of FcepsilonRI-mediated mast cell activation. Cellular Immunology in press

Kato N, Yoshida H, Kioko Ono-Nita S, Kato J, Goto T, Otsuka M, Lan K, Matsushima K, Shiratori Y and Omata M (2000) Activation of intracellular signaling by hepatitis B and C viruses: C- viral core is the most potent signal inducer. Hepatology 32 405-412

Kato S, Yuzawa Y, Tsuboi N, Maruyama S, Morita Y, Matsuguchi T and Matsuo S (2004) Endotoxin-induced chemokine expression in murine peritoneal mesothelial cells: the role of toll-like receptor 4. Journal of American Society of Nephrology 15 1289-1299

Kato Jr T, Delhase M, Hoffmann A and Karin M (2003) CK2 is a C-terminal IkB kinase reponsible for NF-kB activation during the UV response. Molecular Cell 12 829-839

Kato T, Duffey DC, Ondrey FG, Dong G, Chen Z, Cook JA, Mitchell JB and Van Waes C (2000) Cisplatin and radiation sensitivity in human head and neck squamous carcinomas are independently modulated by glutathione and transcription factor NF-kB. Head and Neck 22 748-759

Kato T, Imatani T, Minaguchi K, Saitoh E and Okuda K (2002) Salivary cystatins induce interleukin-6 expression via cell surface molecules in human gingival fibroblasts. Molecular Immunology 39 423-430

Kato T and Kitagawa S (2006) Regulation of neutrophil functions by proinflammatory cytokines. International Journal of Hematology 84 205-209

Kato T, Okahashi N, Kawai S, Kato T, Inaba H, Morisaki I and Amano A (2005) Impaired degradation of matrix collagen in human gingival fibroblasts by the antiepileptic drug phenytoin. Journal of Periodontology 76 941-950

Kato Jr T, Gotoh Y, Hoffmann A, and Ono Y (2008) Negative regulation of constitutive NF-kB and JNK signaling by PKN1-mediated phosphorylation of TRAF1. Genes Cells 13 509-520

Kato Y, Adachi Y and Ohno N (2006) Contribution of N-linked oligosaccharides to the expression and functions of beta-glucan receptor, dectin-1. Biological &Pharmaceutical Bulletin 29 1580-1586

Kato Y, Ozawa S, Tsukuda M, Kubota E, Miyazaki K, St-Pierre Y and Hata R (2007) Acidic extracellular pH increases calcium influx-triggered phospholipase D activity along with acidic sphingomyelinase activation to induce matrix metalloproteinase-9 expression in mouse metastatic melanoma. FEBS Journal 274 3171-3183

Kato Y, Ying H, Zhao L, Furuya F, Araki O, Willingham MC and Cheng SY (2006) PPARgamma insufficiency promotes follicular thyroid carcinogenesis via activation of the nuclear factor-kB signaling pathway. Oncogene 25 2736-2747

Kato Y, Ying H, Willingham MC and Cheng SY (2004) A tumor suppressor role for thyroid hormone {beta} receptor in a mouse model of thyroid carcinogenesis. Endocrinology 145 4430-4438

Kataoh M and Katoh M (2007) Notch signaling in gastrointestinal tract. InternationalJournal of Oncology 30 247-251

Katoh M and Katoh M (2007) AP1- and NF-kB-binding sites conserved among mammalian WNT10B orthologs elucidate the TNFa-WNT10B signaling loop implicated in carcinogenesis and adipogenesis. International Journal of Molecular Medicine 19 699-703

Kataoka H, Yasuda M, Iyori M, Kura K, Narita M, Nakata T and Shibata K (2006) Roles of N-linked glycans in the recognition of microbial lipopeptides and lipoproteins by TLR2. Cellular Microbiology 8 1199-1209

Kato I, Oya T, Suzuki H, Takasawa K, Ichsan AM, Nadaka S, Ishii T, Shimada Y, Sasahara M, Tobe K, Takasawa S, Okamoto H and Hiraga K (2008) A novel model of insulin-dependent diabetes with renal and retinal lesions by transgenic expression of CaMKIIalpha (Thr286Asp) in pancreatic beta-cells. Diabetes and Metabolism Research Reviews in press

Kato S, Nishio H, Ogura M and Takeuchi K (2007) Tacrolimus (FK506), an immunosuppressive agent, prevents indomethacin-induced small intestinal ulceration in the rat: inhibition of inducible nitric oxide synthase expression. Journal ofPharmacological Sciences in press

Katoh M and Katoh M (2007) AP1- and NF-kB-binding sites conserved among mammalian WNT10B orthologs elucidate the TNFalpha-WNT10B signaling loop implicated in carcinogenesis and adipogenesis. International Journal of Molecular Medicine 19 699-703

Katsel PL and Greenstein RJ (2001) Identification of overlapping AP-2/NF-kB-responsive elements on the rat cholecystokinin gene promoter. Journal of Biological Chemistry 276 752-758

Katsman A, Umezawa K and Bonavida B (2007) Reversal of resistance to cytotoxic cancer therapies: DHMEQ as a chemo-sensitizing and immuno-sensitizing agent. Drug Resistance Updates in press

Katsuyama K, Shichiri M, Kato H, Imai T, Marumo F and Hirata Y (1999) Differential inhibitory actions by glucocorticoid and aspirin on cytokine-induced nitric oxide production in vascular smooth muscle cells. Endocrinology 140 2183-2190

Katsuyama K, Shichiri M, Marumo F and Hirata Y (1998) NO inhibits cytokine-induced iNOS expression and NF-kB activation by interfering with phosphorylation and degradation of IkB-a. Arteriosclerosis, Thrombosis and Vascular Biology 18 1796-1802

Katsuyama K, Shichiri M, Marumo F and Hirata Y (1998) Role of Nuclear Factor-kB activation in cytokine- and sphingomyelinase-stimulated inducible nitric oxide synthase gene expression in vascular smooth muscle cells. Endocrinology 139 4506-4512

Katula KS, McCain JA and Radewicz AT (2005) Relative ability of dietary compounds to modulate nuclear factor-kappaB activity as assessed in a cell-based reporter system.Journal of Medicinal Food 8 269-274

Katz J, Zhang P, Martin M, Vogel SN and Michalek SM (2006) Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS. Infection andImmunity 74 2809-2816

Katz JA, Itoh J and Fiocchi C (1999) Pathogenesis of inflammatory bowel disease.Current Opinion in Gastroenterology 15 291

Kaufmann JA, Bickford PC and Taglialatela G (2002) Free radical-dependent changes in constitutive Nuclear factor kB in the aged hippocampus. Neuroreport 13 1917-1920

Kaufman PA, Weinberg JB and Greene WC (1992) Nuclear expression of the 50- and 65-kD Rel-related subunits of Nuclear Factor-kB is differentially regulated in human monocytic cells. Journal of Clinical Investigation 90 121-129

Kaufman RJ (1999) Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: a new role for an old actor. Proceedings of the National Academy of Sciences USA 96 11693-11695

Kaufman RJ (1999) Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes & Development 13 1211-1233

Kaul DK, Liu XD, Choong S, Belcher JD, Vercellotti GM and Hebbel RP (2004) Anti-inflammatory therapy ameliorates leukocyte adhesion and microvascular flow abnormalities in transgenic sickle mice. American Journal of Physiology: Heart and Circulatory Physiology 287 H293-H301

Kaul R, Verma SC, Murakami M, Lan K, Choudhuri T and Robertson ES (2006) Epstein-Barr virus protein can upregulate cyclo-oxygenase-2 expression through association with the suppressor of metastasis Nm23-H1. Journal of Virology 80 1321-1331

Kaul S, Cercek B, Rengstrom J, Xu XP, Molloy MD, Dimayuga P, Parikh AK, Fishbein MC, Nilsson J, Rajavashisth TB and Shah PK (2000) Polymeric-based perivascular delivery of a nitric oxide donor inhibits intimal thickening after balloon denudation arterial injury: role of nuclear factor-kB. Journal of the American College of Cardiology 35 493-501

Kauppinen TM, Higashi Y, Suh SW, Escartin C, Nagasawa K and Swanson RA (2008) Zinc triggers microglial activation. Journal of Neuroscience 28 5827-5835

Kauppinen TM and Swanson RA (2005) Poly(ADP-Ribose) Polymerase-1 promotes microglial activation, proliferation, and matrix metalloproteinase-9-mediated neuron death.Journal of Immunology 174 2288-2296

Kauppinen TM and Swanson RA (2006) The role of poly(ADP-ribose) polymerase-1 in CNS disease. Neuroscience in press

Kaur H Chen S, Xin X, Chiu J, Khan ZA and Chakrabarti S (2006) Diabetes-induced extracellular matrix protein expression is mediated by transcription coactivator p300. Diabetes 55 3104-3111

Kaur J, Woodman RC, Ostrovsky L and Kubes P (2001) Selective recruitment of neutrophils and lymphocytes by thrombin: a role for NF-kB. American Journal of Physiology: Heart and Circulatory Physiology 281 H784-H795

Kaur M and Agarwal R (2007) Transcription factors: molecular targets for prostate cancer intervention by phytochemicals. Current Cancer Drug Targets 7 355-367

Kaur M Holden NS, Wilson SM, Sukkar MB, Chung KF, Barnes PJ, Newton R and Giembycz MA (2008) Effect of {beta}2-adrenoceptor agonists and other cAMP-elevating agents on inflammatory gene expression in human airways smooth muscle cells: A role for protein kinase A. American Journal of Physiology: Lung Cell and Molecular Physiology in press

Kaur P, Kaur G and Bansal MP (2006) Tertiary-butyl hydroperoxide induced oxidative stress and male reproductive activity in mice: Role of transcription factor NF-kB and testicular antioxidant enzymes. Reproductive Toxicology22 479-484

Kaur S, Wang F, Venkatraman M and Arusra M (2005) X-linked inhibitor of apoptosis (XIAP) inhibits c-Jun N-terminal kinase1 (JNK1) activation by transforming growth factor-beta 1 (TGF-beta 1) through ubiquitin-mediated proteosomal degradation of the TGF-beta 1-activated kinase1 (TAK1). Journal of Biological Chemistry 280 38599-38608

Kaushal V, Koeberle PD, Wang Y and Schlichter LC (2007) The Ca2+-activated K+ channel KCNN4/KCa3.1 contributes to microglia activation and nitric oxide-dependent neurodegeneration. Journal of Neuroscience 27 234-244

Kaushal V, adn Schlichter LC (2008) Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra. Journal of Neuroscience 28 2221-2230

Kavnkova K, Vojtevsek B and Valik D (2001) The Rel/NF-kB transcription factors and their biological functions [Article in Czech]. Cas Lek Cesk 140 163-167

Kavuma MM, Schoppet M, Robryshev YV, Khachigian LM and Bennett MR (2008) TRAIL stimulates proliferation of vascular smooth muscle cells via activation of NF-kB and induction of insulin-like growth factor-1 receptor. Journal of Biological Chemistry 283 7754-7762

Kawabata Y, Furuta S, Shinozaki Y, Kurimoto T and Nishigaki R (2002) Carrier-mediated active transport of a novel thromboxane A(2) receptor antagonist [2-(4-chlorophenylsulfonylaminomethyl)indan-5-yl]acetate (Z- 335) into rat liver. Drug Metab Dispos 30 498-504

Kawada N, Seki S, Kuroki T and Inoue M (1998) Regulation of stellate cell proliferation by lipopolysaccharide: role of endogenous nitric oxide. Journal of Gastroenterology and Hepatology 13 S6-S13

Kawagoe J, Ohmichi M, Takahashi T, Ohshima C, Mabuchi S, Takahashi K, Igarashi H, Mori-Abe A, Saitoh M, Du B, Ohta T, Kimura A, Kyo S, Inoue M and Kurachi H (2003) Raloxifene inhibits estrogen-induced up-regulation of telomerase activity in a human breast cancer cell line. Journal of Biological Chemistry 278 43363-43372

Kawagoe T, Sato S, Jung A, Yamamoto M, Matsui K, Kato H, Uematsu S, Takeuchi O and Akira S (2007) Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor- mediated immune responses but not in TCR signaling. Journal ofExperimental Medicine 204 1013-1024

Kawagoe T, Sato S, Matsushita K, Kato H, Matsui K, Kumagai Y, Sitoh T, Kawai T, Takeuchi O and Akira S (2008) Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2. Nature Immunology in press

Kawahara T, Kuwano Y, Teshima-Kondo S, Kawai T, Nikawa T, Kishi K and Rokutan K (2001) Toll-like receptor 4 regulates gastric pit cell responses to Helicobacter pylori infection. Journal of Molecular Investigation 48 190-197

Kawahara T, Kuwano Y, Teshima-Kondo S, Takeya R, Sumimoto H, Kishi K, Tsunawaki S, Hirayama T and Rokutan K (2004) Role of nicotinamide adenine dinucleotide phosphate oxidase 1 in oxidative burst response to Toll-like receptor 5 signaling in large intestinal epithelial cells. Journal of Immunology 172 3051-3058

Kawai H, Nie L and Yuan ZM (2002) Inactivation of NF-kB-dependent cell survival, a novel mechanism for the proapoptotic function of c-Abl. Molecular and Cellular Biology 22 6079-6088

Kawai H, Yamada Y, Tatsuka M, Niwa O, Yamamoto K and Suzuki F (1999) Down-regulation of nuclear factor kB is required for p53-dependent apoptosis in X-ray-irradiated mouse lymphoma cells and thymocytes. Cancer Research 59 6038-6041

Kawai N, Shimada M, Kawahara H, Satoh N and Yokosawa H (2003) Regulation of ascidian Rel by its alternative splice variant. European Journal of Biochemistry 270 4459-4468

Kawai N, Takahashi H, Nishida H and Yokosawa H (2004) Regulation of NF-kB/Rel by IkB is essential for ascidian notochord formation. Developmental Biology 277 80-91

Kawai S, Kataoka T, Sugimoto H, Nakamura A, Kobayashi T, Arao K, Higuchi Y, Ando M and Nagai K (2000) Santonin-related compound 2 inhibits the expression of ICAM-1 in response to IL-1 stimulation by blocking the signaling pathway upstream of IkB degradation. Immunopharmacology 48 129-135

Kawai T and Akira S (2005) Toll-like receptor downstream signaling. Arthritis Research and Therapy 7 12-19

Kawai T and Akira S (2006) TLR signaling. Cell Death and Differentiation 13 816-825

Kawai T and Akira S (2006) Role of IPS-1 in type I IFN induction [Article in Japanese]. Nippon Rinsho 64 1231-1235

Kawai T and AKira S (2007) Signaling to NF-kB by Toll-like receptors. Trends in Molecular Medicine in press

Kawai T, Takahashi K, Sato S, Coban C, Kumar H, Kato H, Ishitt KJ, Takeuchi O and Akira S (2005) IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nature Immunology 6 981-988

Kawakami A, Aikawa M, Nitta N, Yoshida M, Kibby P and Sacks FM (2006) Apolipoprotein CIII-induced THP-1 cell adhesion to endothelial cells involves Pertussis toxin-sensitive G protein- and protein kinase Ca-mediated nuclear factor-kB activation.Arteriosclerosis, Thrombosis and Vascular Biology 27 219-225

Kawakami A, Nakashima K, Tamai M, Nakamura H, Iwanaga N, Fujikawa K, Aramaki T, Arima K, Iwamoto N, Ichinose K, Kamachi M, Ida H, Origuchi T and Eguchi K (2007) Toll-like receptor in salivary glands from patients with Sjogren’s Syndrome: functional analysis by human salivary gland cell line. Journal of Rheumatology in press

Kawakami H, Tomita M, Matsuda T, Ohta T, Tanaka Y, Fujii M, Hatano M, Tokuhisa T and Mori N (2005) Transcriptional activation of survivin through the NF-kB pathway by human T-cell leukemia virus type I tax. International Journal of Cancer 115 967-974

Kawakami H, Tomita M, Okudaira T, Ishikawa C, Matsuda T, Tanaka Y, Nakazato T, Taira N, Ohshiro K and Mori N (2007) Inhibition of heat shock protein-90 modulates multiple functions required for survival of human T-cell leukemia virus type I-infected T-cell lines and adult T-cell leukemia cells. International Journal of Cancer 120 1811-1820

Kawakita Y, Ikekita M, Kurozumi R and Kojima S (2003) Increase of intracellular glutathione by low-dose gamma-ray irradiation is mediated by transcription factor AP-1 in RAW 264.7 cells. Biol Pharm Bull 26 19-23

Kawakami A, Aikawa M, Alcaide P, Luscinskas FW, Libby P and Sacks FM (2006) Apolipoprotein CIII induces expression of vascular cell adhesion molecule-1 in vascular endothelial cells and increases adhesion of monocytic cells. Circulation114 681-687

Kawakami A and Eguchi K (2002) Involvement of apoptotic cell death in autoimmune diseases. Medical Electron Microscopy 35 1-8

Kawakami A, Nakashima T, Sakai H, Urayama S, Yamasaki S, Hida A, Tsuboi M, Nakamura H, Ida H, Migita K, Kawabe Y and Eguchi K (1999) Inhibition of caspase cascade by HTLV-I tax through induction of NF-kB nuclear translocation. Blood 94 3847-3854

Kawakami K, Scheidereit C and Roeder RG (1988) Identification and purification of the human immunoglobulin-enhancer binding protein (NF-kB) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro. Proceedings of the National Academy of Sciences USA 85 4700-4704

Kawakami S, Ito Y, Charoensit P, Yamasnita F and Hashida M (2006) Evaluation of proinflammatory cytokine production induced by linear and branched polyethylenimine/plasmid DNA complexes in mice. Journal of Pharmacology andExperimental Therapeutics 317 1382-1390

Kawamoto T, Ii M, Kitazaki T, Iizawa Y and Kimura H (2008) TAK-242 selectively suppresses Toll-like receptor 4-signaling mediated by the intracellular domain. European Journal of Immunology in press

Kawamura A, Baitsch D, Telgmann R, Feuerborn R, Weissen-Plenz G, Hagedorn C, Saku K, Brand-Herrmann SM, von Eckardstein A, Assmann G and Nofer JR (2007) Apolipoprotein E interrupts interleukin-1beta signaling in vascular smooth muscle cells.Arteriosclerosis,  Thrombosis, and Vascular Biology 27 1610-1617

Kawamura N, Dyck PJ, Schmeichel AM, Engelstad JK, Low PA and Dyck PJ (2007) Inflammatory mediators in diabetic and non-diabetic lumbosacral radiculoplexus neuropathy. Acta Neuropatholica in press

Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, Sinoda Y, Kawasaki Y, Ogata N, Hoshi K, Akiyama T, Chen WS, Hay N, Tobe K, Kadowaki T, Azuma Y, Tanaka S, Nakamura K, Chung UI and Kawaguchi H (2007) Akt1 in osteoblasts and osteoclasts controls bone remodeling. PLoS ONE 2 e1058

Kawamura N, Schmeichel AM, Wang Y, Schmelzer JD and Low PA (2006) Multiple effects of hypothermia on inflammatory response following ischemia-reperfusion injury in experimental ischemic neuropathy. Experimental Neurology 202 487-496

Kawakita T, Shiraki K, Yamanaka Y, Yamaguchi Y, Saitou Y, Enokimura N, Yamamoto N, Okano H, Sugimoto K, Murata K and Nakano T (2004) Functional expression of TWEAK in human hepatocellular carcinoma: possible implication in cell proliferation and tumor angiogenesis. Biochemical and Biophysical Research Communications 318 726-733

Kawakita T, Shiraki K, Yamanaka Y, Yamaguchi Y, Saitou Y, Enokimura N, Yamamoto N, Okano H, Sugimoto K, Murata K and Nakano T (2005) Functional expression of TWEAK in human colonic adenocarcinoma cells. International Journal of Oncology 26 87-93

Kawakubo H, Carey JL, Brachtel E, Gupta V, Green JE, Walden PD and Maheswaran S (2004) Expression of the NF-kB-responsive gene BTG2 is aberrantly regulated in breast cancer. Oncogene 23 8310-8319

Kawamata S, Hori T, Imura A, Takaori-Kondo A and Uchiyama T (1998) Activation of OX40 signal transduction pathways leads to tumor necrosis factor receptor-associated factor (TRAF) 2 and TRAF5-mediated NF-kB activation. Journal of Biological Chemistry 273 5808-5814

Kawamoto EM, Lepsch LB, Boaventura MF, Munhoz CD, Lima LS, Yshii LM, Avellar MC, Curi R, Mattson MP and Scavone C (2007) Amyloid beta-peptide activates nuclear factor-kB through an N-methyl-D-aspartate signaling pathway in cultured cerebellar cells. Journal of Neuroscience Research in press

Kawana H, Karaki H, Higasti M, Miyazaki M, Hilberg F, Kitagawa M and Harigaya K (2008) CD44 suppresses TLR-mediated inflammation. Journal of Immunology 180 4235-4245

Kawaoka S, Katusuma S, Daimon T, Isono R, Omuro N, Mita K and Shimada T (2007)Functional analysis of four Gloverin-like genes in the silkworm, Bombyx mori. Archives of Insect Biochemistry and Physiology in press

Kawauchi K, Tobiume K, Kaneko S, Kaneshiro K, Okamoto S, Ueda E, Kamata H, Moriyama Y and Hirato H (2007) Suppression of AP-1 activity by cycloprodigiosin hydrochloride. Biol Pharm Bull 30 1792-1795

Kawamura H, Wakabayshi T, Yamaguchi S, Taniguchi T, Takayanagi N, Sato S, Sekiya S and Horiuchi T (1976) Incoulation experiment of Marek’s disease vaccine contaminated with reticuloendotheliosis virus. National Institute of Animal Health Quarterly 16 135-140

Kawamura I, Morishita R, Tomita N, Lacey E, Aketa M, Tsujimoto S, Manda T, Tomoi M, Kida I, Higaki J, Kaneda Y, Shimomura K and Ogihara T (1999) Intratumoral injection of oligonucleotides to the NF kB binding site inhibits cachexia in a mouse tumor model. Gene Therapy 6 91-97

Kawamura I, Morishita R, Tsujimoto S, Manda T, Tomoi M, Tomita N, Goto T, Ogihara T and Kaneda Y (2001) Intravenous injection of oligodeoxynucleotides to the NF-kB binding site inhibits hepatic metastasis of M5076 reticulosarcoma in mice. Gene Therapy 8 905-912

Kawamura M, Kasai H, He L, Deng X, Yamashita A, Terunuma H, Horiuchi I, Tanabe F and Ito M (2005) Antithetical effects of hemicellulase-treated Agaricus blazei on the maturation of murine bone-marrow-derived dendritic cells. Immunology 114 397-409

Kawamura N, Kubota T, Kawano S, Monden Y, Feldman AM, Tsutsui H, Takeshita A and Sunagawa K (2005) Blockade of NF-kB improves cardiac function and survival without affecting inflammation in TNF-a-induced cardiomyopathy. Cardiovascular Research 66 520-529

Kawamura T, Kadosaki M, Nara N, Wei J, Endo S and Inada K (2005) Nicorandil attenuates NF-kB activation, adhesion molecule expression, and cytokine artery bypass surgery. Shock 24 103-108

Kawamura YI, Kawashima R, Shirai Y, Kato R, Hamabata T, Yamamoto M, Furukawa K, Fujihashi K, McGhee JR, Hayashi H and Dohi T (2003) Cholera toxin activates dendritic cells through dependence on GM1-ganglioside which is mediated by NF-kB translocation. European Journal of Immunology 33 3205-3212

Kawanami D, Maemura K, Takeda N, Harada T, Jojiri T, Saito T, Manabe I, Imai Y and Nagai R (2005) C-reactive protein induces VCAM-1 gene expression through NF-kB activation in vascular endothelial cells. Atherosclerosis 185 39-46

Kawano S, Kubota T, Monden Y, Kawamura N, Tsutsui H, Takeshita A and Sunagawa K (2005) Blockade of NF-kB ameliorates myocardial hypertrophy in response to chronic infusion of angiotensin II. Cardiovascular Research 67 689-698

Kawano S, Kubota T, Monden Y, Tsutsumi T, Inoue T, Kawamura N, Tsutsui H and Sunagawa K (2006) Blockade of NF-kB improves cardiac function and survival after myocardial infarction. American Journal of Physiology: Heart and CirculatoryPhysiology in press

Kawano T, Ahmad R, Nogi H, Agata N, Anderson K and Kufe D (2008) MUC1 oncoprotein promotes growth and survival of human multiple myeloma cells. International Journal of Oncology 33 153-159

Kawano T, Matsuse H, Kondo Y, Machida I, Saeki S, Tomari S, Mitsuta K, Obase Y, Fukushima C, Shimoda T and Kohno S (2003) Cysteinyl leukotrienes induce nuclear factor kb activation and rantes production in a murine model of asthma. Journal of Allergy and Clinical Immunology 112 369-374

Kawasaki K, Akashi S, Shimazu R, Yoshida T, Miyake K and Nishijima M (2000) Mouse toll-like receptor 4.MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by Taxol. Journal of Biological Chemistry 275 2251-2254

Kawasaki K, Ernst RK and Miller SI (2004) 3-O-deacylation of lipid A by PagL, a PhoP/PhoQ-regulated deacylase of Salmonella typhimurium, modulates signaling through toll-like receptor 4. Journal of Biological Chemistry 279 20044-20448

Kawashima S, Hayashi M, Takii T, Kimura H, Zhang HL, Nagatsu A, Sakakibara J, Murata K, Oomoto Y and Onozaki K (1998) Serotonin derivative, N-(p-coumaroyl) serotonin, inhibits the production of TNF-a, IL-1a, IL-1b, and IL-6 by endotoxin-stimulated human blood monocytes. Journal of Interferon and Cytokine Research 18 423-428

Kawashima T, Murata K, Akira S, Tonozuka Y, Minoshima Y, Feng S, Kumagai H, Tsuruga H, Ikeda Y, Asano S, Nosaka T and Kitamura T (2001) STAT5 induces macrophage differentiation of M1 leukemia cells through activation of IL-6 production mediated by NF-kB p65. Journal of Immunology 167 3652-3660

Kawata S, Ariumi Y and Shimotohno K (2003) p21(Waf1/Cip1/Sdi1) prevents apoptosis as well as stimulates growth in cells transformed or immortalized by human T-cell leukemia virus type 1-encoded Tax. Journal of Virology 77 7291-7299

Kawauchi K, Araki K, Tobiume K and Tanaka N (2008) p53 regulates glucose metabolism through an IKK-NF-kB pathway and inhibits cell transformation. Nature Cell Biology in press

Kawauchi K, Araki K, Tobiume K and Tanaka N (2008) Activated p53 induces NF-kB DNA binding but suppresses its transcriptional activation. Biochemical and Biophsyical Research Communications in press

Kayal S, Lilienbaum A, Join-Lambert O, Li X, Israel A and Berche P (2002) Listeriolysin O secreted by Listeria monocytogenes induces NF-kB signalling by activating the IkB kinase complex. Molecular Microbiology 44 1407-1419

Kayal S, Lilienbaum A, Poyart C, Memet S, Israel A and Berche P (1999) Listeriolysin O-dependent activation of endothelial cells during infection with Listeria monocytogenes: activation of NF-kB and upregulation of adhesion molecules and chemokines. Molecular Microbiology 31 1709-1722

Kayama H, Ramirez-Carrozzi VR, Yamamoto M, Mintani T, Kuwata H, Iba H, Matsumoto M, Honda K, SMale ST and Takeda K (2008) Class-specific regulation of pro-inflammatory genes by MYD88 pathways and IkBzeta. Journal of Biological Chemistry 283 12468-12477

Kaye KM, Izumi KM, Li H, Johannsen E, Davidson D, Longnecker R and Kieff E (1999) An Epstein-Barr virus that expresses only the first 231 LMP1 amino acids efficiently initiates primary B-lymphocyte growth transformation. Journal of Virology 73 10525-10530

Kaykas A, Worringer K and Sugden B (2002) LMP-1′s transmembrane domains encode multiple functions required for LMP-1′s efficient signaling. Journal of Virology 76 11551-11560

Kazama S, Ajioka Y, Watanabe H, Watanabe T and Nagawa H (2002) Histogenesis and morphogenesis of depressed-type early colorectal carcinoma. Pathology International 52 119-125

Kazi A, Daniel KG, Smith DM, Kumar NB and Dou QP (2003) Inhibition of the proteasome activity, a novel mechanism associated with the tumor cell apoptosis-inducing ability of genistein. Biochemical Pharmacology 66 965-976

Kazi A, Wang Z, Kumar N, Falsetti SC, Chan TH and Dou QP (2004) Structure-activity relationships of synthetic analogs of (-)-epigallocatechin-3-gallate as proteasome inhibitors. Anticancer Research 24 943-954

Kazmi S, Plante R, Visconte V, Taylor GR, Zhou L and Lau CY (1995) Suppression of NFkB-dependent gene expression by tepoxalin, a dual inhibitor of cyclooxygenase and 5-lipoxygenase. Journal of Cellular Biochemistry 57 299-310

Kazzaz JA, Horowitz S, Li Y and Mantell LL (1999) Hyperoxia in cell culture. A non-apoptotic programmed cell death. Annals of the New York Academy of Sciences 887 164-170

Ke B, Shen XD, Tsuchihashi SI, Gao F, Araujo JA, Busuttil RW, Ritter T and Kupiec-Weglinski JW (2007) Viral interleukin-10 gene transfer prevents liver ischemia-reperfusion injury: Toll-like receptor-4 and heme oxygenase-1 signaling in innate and adaptive immunity. Human Gene Therapy in press

Ke J, Long X, Liu Y, ZXhang YF, Li J, Fang W and Meng QG (2007) Role of NF-kB in TNF-alpha-induced COX-2 expression in synovial fibroblasts from human TMJ. Journal of Dental Research 86 363-367

Ke JJ, Wang YL, Li JG, Wu J and Feng XB (2004) Pretreatment effect of adenosine on activation of NF-kB and level of TNF-alpha during myocardial ischemia and reperfusion in rats. Chinese Journal of Traumatology 7 25-27

Ke XY, Gribben J, Wang J and Wang DB (2002) The Identical Effects of B7-1 and B7-2 on regulation of human IL-2 gene transcription factors NF-kB and AP-1 [Article in Chinese]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 10 512-518

Kean WF (2004) Oxaprozin: kinetic and dynamic profile in the treatment of pain. Current Medical Research Opinion 20 1275-1277

Keane CJ, Hanlon AJ, Roche JF, Burton JL, Mee JF, O’Doherty JV and Sweeney T (2006) A potential antiapoptotic phenotype in neutrophils of cows milked once daily in early lactation. Journal of Dairy Science in press

Keane MM, Rubinstein Y, Cuello M, Ettenberg SA, Banerjee P, Nau MM and Lipkowitz S (2001) Inhibition of NF-kB activity enhances TRAIL mediated apoptosis in breast cancer cell lines. Breast Cancer Research and Treatment 64 211-219

Kearns JD, Basak S, Werner SL, Huang CS and Hoffmann A (2006) IkBepsilon provides negative feedback to control NF-kB oscillations, signaling dynamics, and inflammatory gene expression. Journal of Experimental Medicine 203 in press

Keates S, Keates AC, Warny M, Peek RM, Jr., Murray PG and Kelly CP (1999) Differential activation of mitogen-activated protein kinases in AGS gastric epithelial cells by cag+ and cag- Helicobacter pylori. Journal of Immunology 163 5552-5559

Keating SE, Maloney GM, Moran EM and Bowie AG (2007) IRAK-2 participates in multiple Toll-like receptor signaling pathways to NFkB via activation of TRAF6 ubiquitination. Journal of Biological Chemistry 282 33435-33443

Keats JJ, Fonseca R, Chesi M, Schop R, Baker A, Chng WJ, Van Wier S, Tiedemann R, Shi CX, Sebag M, Braggio E, Henry T, Zhu YX, Fogle H, Price-Troska T, Ahmann G, Mancini C, Brents LA, Kumar S, Greipp P, Dispenzieri A, Bryant B, Julligan G, Bruhn L, Barrett M, Valdez R, Trent J, Stewart AK, Carpten J and Bergsagel PL (2007) Promiscuous mutations activate the noncanonical NF-kB pathway in multiple myeloma.Cancer Cell 12 131-144

Kedar PS, Arden K, Foyle M, Pope JH and Zeichner SL (2002) Umbilical cord blood mononuclear cell HIV-1 LTR binding activities. Journal of Biomedical Sciences 4 217-222

Keel M, Mica L, Stover J, Stocker R, Trentz O and Harter L (2005) Thiopental-induced apoptosis in lymphocytes is independent of CD95 activation. Anesthesiology 103 576-584

Keestra AM, de Zoete MR, van Aubel RA and van Putten JP (2007) The central leucine-rich repeat region of chicken TLR16 dictates unique ligand specificity and species-specific interaction with TLR2. Journal of Immunology 178 7110-7719

Keestra AM, de Zoete MR, van Aubel RA and van Putten JP (2007) Functional characterization of chicken TLR5 reveals species-specific recognition of flagellin.Molecular Immunology in press

Kefaloyianni E, Gaitanaki C and Beis I (2006) ERK1/2 and p38-MAPK signalling pathways, through MSK1, are involved in NF-kB transactivation during oxidative stress in skeletal myoblasts. Cellular Signaling 18 2238-2251

Kefer J, Rahman A, Anwar KN and Malik AB (2001) Decreased oxidant buffering impairs NF-kB activation and ICAM-1 transcription in endothelial cells. Shock 15 11-15

Kehry MR (1996) CD-40-mediated signaling in B cells. Balancing cell survival, growth, and death. Journal of Immunology 156 2345-2348

Keicho N, Higashimoto Y, Bondy GP, Elliott WM, Hogg JC and Hayashi S (1999) Endotoxin-specific NF-kB activation in pulmonary epithelial cells harboring adenovirus E1A. American Journal of Physiology 277 L523-L532

Keifer JA, Guttridge DC, Ashburner BP and Baldwin AS Jr (2001) Inhibition of NF-kB activity by thalidomide through suppression of IkB kinase activity. Journal of Biological Chemistry 276 22382-22387

Keightley AM, Lam YM, Brady JN, Cameron CL and Lillicrap D (1999) Variation at the von Willebrand factor (vWF) gene locus is associated with plasma vWF:Ag levels: identification of three novel single nucleotide polymorphisms in the vWF gene promoter. Blood 93 4277-4283

Keiss HP, Dirsch VM, Hartung T, Haffner T, Trueman L, Auger J, Kahane R and Vollmar AM (2003) Garlic (Allium sativum L.) modulates cytokine expression in lipopolysaccharide-activated human blood thereby inhibiting NF-kB activity. Journal of Nutrition 133 2171-2175

Keith Jr JC, Albert LM, Leathurby Y, Follettie M, Wang L, Borges-Marcucci L, Chadwick CC, Steffan RJ and Harnish DC (2005) The utility of pathway selective estrogen receptor ligands that inhibit nuclear factor-kB transcriptional activity in models of rheumatoid arthritis. Arthritis Research and Therapy 7 R427-R438

Kekuda R, Leibach FH, Furesz TC, Smith CH and Ganapathy V (2000) Polarized distribution of interleukin-1 receptors and their role in regulation of serotonin transporter in placenta. J Pharmacol Exp Ther 292 1032-1041

Kékule AS, Lauer U, Weiss L, Luber B and Hofschneider PH (1993) Hepatitis B virus transactivator HBx uses a tumor promoter signalling pathway. Nature 361 742-745

Kelleher ZT, Matsumoto A, Stamler JS and Marshall HE (2007) NOS2 regulation of NF-kB by S-nitrosylation of p65. Journal of Biological Chemistry 282 40667-30672

Keller ET (2004) Metastasis suppressor genes: a role for raf kinase inhibitor protein (RKIP). Anticancer Drugs 15 663-669

Keller ET, Fu Z and Brennan M (2004) The biology of a prostate cancer metastasis suppressor protein: Raf kinase inhibitor protein. J Cell Biochem 94 273-278

Keller ET, Fu Z, Yeung K and Brennan M (2004) Raf kinase inhibitor protein: a prostate cancer metastasis suppressor gene. Cancer Letters 207 131-137

Keller LH, Rutner R and Sevoian M (1979) Isolation and development of a reticuloendotheliosis virus-transformed lymphoblastoid cell line from chicken spleen cells. Infection & Immunity 25 694-701

Keller SA, Hernandez-Hopkins D, Vider J, Pnomarev V, Hyjek E, Schattner EJ and Cesarman E (2005) NF-kB is essential for progression of KSHV- and EBV-infected lymphomas in vivo. Blood in press

Keller SH, Platoshyn O and Yuan JX (2005) Long QT syndrome-associated I593R mutation in HERG potassium channel activates ER stress pathways. Cell Biochem Biophys 43 365-378

Keller U, Nilsson JA, Maclean KH, Old JB and Cleveland JL (2005) Nfkb1 is dispensable for Myc-induced lymphomagenesis. Oncogene 24 6231-6240

Kellum JA, Song M and Almasri E (2006) Hyperchloremic acidosis increases circulating inflammatory molecules in experimental sepsis. Chest 130 962-967

Kellum JA, Song M and Li J (2003) Lactic, and hydrochloric acids induce different patterns of inflammatory response in LPS-stimulated RAW 264.7 cells. American Journal of Physiology: Regulotry, Integrative and Comparative Physiology 286 R686-R692

Kellum JA, Song M and Venkataraman R (2004) Hemoadsorption removes tumor necrosis factor, interleukin-6, and interleukin-10, reduces nuclear factor-kappaB DNA binding, and improves short-term survival in lethal endotoxemia. Critical Care Medicine 32 801-805

Kelly A, Vereker E, Nolan Y, Brady M, Barry C, Loscher CE, Mills KH and Lynch MA (2003) Activation of p38 plays a pivotal role in the inhibitory effect of lipopolysaccharide and interleukin-1beta on long-term potentiation in rat dentate gyrus. Journal of Biological Chemistry 278 19453-19462

Kelly D, Campbell JI, King TP, Grant G, Jansson EA, Coutts AG, Pettersson S and Conway S (2003) Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA. Nature Immunology 5 104-112

Kelly D, Conway SBacterial modulation of mucosal innate immunity. Molecular Immunology 42 895-901

Kelly GD, Morris CB and Offermann MK (1999) Lack of responsiveness of a nuclear factor-kB-regulated promoter to transactivation by human immunodeficiency virus 1 Tat in HeLa cells. Virology 263 128-138

Kelly JM, Moir AJ, Carlson K, Yang Y, Macneil S and Haycock JM (2005) Immobilized alpha-melanocyte stimulating hormone 10-13 (GKPV) inhibits tumor necrosis factor-a stimulated NF-kB activity. Peptides 27 431-437

Kelly KA, Hill MR, Youkhana K, Wanker F and Gimble JM (1994) Dimethyl sulfoxide modulates NF-kB and cytokine activation in lipopolysaccharide-treated murine macrophages. Infection & Immunity 62 3122-3128

Kelschenbach J, Ninkovic J, Wang J, Krishnan A, Charboneau R, Barke RA and Roy S (2008) Morphine withdrawal inhibits IL-12 induction in a macrophage cell line through a mechanism that involves cAMP. Journal of Immunology 180 3670-3679

Kemler I and Fontana A (1999) Role of IkappaBalpha and IkBb in the biphasic nuclear translocation of NF-kB in TNFa-stimulated astrocytes and in neuroblastoma cells. Glia 26 212-220

Kempe S, Kestler H, Lasar A and Wirth T (2005) NF-kB controls the global pro-inflammatory response in endothelial cells: evidence for the regulation of a pro-atherogenic program. Nucleic Acids Research 33 5308-5319

Kempf VA, Schairer A, Neumann D, Grassl GA, Lauber K, Lebiedziejewski M, Schaller M, Kyme P, Wesselborg S, Autenrieth IB (2005) Bartonella henselae inhibits apoptosis in Mono Mac 6 cells. Cellular Microbiology 7 91-104

Kempiak SJ, Hiura TS and Nel AE (1999) The Jun kinase cascade is responsible for activating the CD28 response element of the IL-2 promoter: proof of cross-talk with the IkB kinase cascade. Journal of Immunology 162 3176-3187

Kempuraj D, Huang M, Kandere-Grzybowska K, Basu S, Boucher W, Letourneau R, Athanassiou A and Theoharides TC (2003) Azelastine inhibits secretion of IL-6, TNF-a and IL-8 as well as NF-kB activation and intracellular calcium ion levels in normal human mast cells. International Archives of Allergy and Immunology 132 231-239

Kennedy JC, Memet S and Wells PG (2004) Antisense evidence for nuclear factor-kB-dependent embryopathies initiated by phenytoin-enhanced oxidative stress. Molecular Pharmacology 66 404-412

Kennedy MW, Green KA, Ford RL, Andrews PG, Paterno GD, Gillespie LL and Kao KR (2007) Regulation of the response to Nodal-mediated mesoderm induction by Xrel3.Develpmental Biology in press

Kennedy T, Shio AJ, Reed W, Samet J, Zagorski J, Quay J, Carter J, Dailey L, Hoidal JR and Devlin RB (1998) Copper-dependent inflammation and Nuclear Factor-kB activation by particulate air pollution. American Journal of Respiratory Cell and Molecular Biology 19 366-378

Kent L, Smyth L, Clayton C, Scott L, Cook T, Stephens R, Fox S, Hext P, Farrow S and Singh D (2008) Cigarette smoke extract induced cytokine and chemokine gene expression changes in COPD macrophages. Cytokine inpress

Kenter AL, Wuerffel R, Dominguez C, Shanmugam A and Zhang H (2004) Mapping of a functional recombination motif that defines isotype specificity for {micro}->{gamma}3 switch recombination implicates NF-kB p50 as the isotype-specific switching factor. Journal of Experimental Medicine 199 617-627

Kenter AL, Wuerffel R, Sen R, Jamieson CE and Merkulov GV (1993) Switch recombination breakpoints occur at nonrandom positions in the Sg tandem repeat. Journal of Immunology 151 4718-4731

Kenwrick S (2002) Incontinentia pigmenti: the first single gene disorder due to disrupted NF-kB function. Ernst Schering Research Foundation Workshop 36 95-107

Kenwrick S and The International IP Consortium (2001) Survival of male patients with incontinentia pigmenti carrying a lethal mutation can be explained by somatic mosaicism or Klinefelter syndrome. American Journal of Human Genetics 69 1210-1217

Kenzel S, Mancuso G, Malley R, Teti G, Golenbock DT andHenneke P (2006) c-Jun kinase is a critical signaling molecule in a neonatal model of group B Streptococcal sepsis. Journal of Immunology 176 3181-3188

Kerbauy DB and Deeg HJ (2007) Apoptosis and antiapoptotic mechanisms in the progression of myelodysplastic syndrome. Experimental Hematology 35 1739-1746

Kerbauy DM, Lesnikov V, Abbasi N, Seal S, Scott B and Deeg HJ (2005) NF-kB and FLIP in arsenic trioxide (ATO)-induced apoptosis in myelodysplastic syndromes (MDS). Blood 106 3917-3925

Kerecman J, Mustafa SB, Vasquez MM, Dixon PS and Castro R (2008) Immunosuppressive properties of surfactant in alveolar macrophage NR8383. Inflammation Research 57 118-125

Kern C, Cornuel JF, Billard C, Tang R, Rouillard D, Steunou V, Defrance T, Ajchenbaum-Cymbalista F, Simonin PY, Feldblum S and Kolb JP (2003) Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway. Blood 103 679-688

Kern JC and Kehrer JP (2005) Free radicals and apoptosis: relationships with glutathione, thioredoxin, and the BCL family of proteins. Frontiers in Bioscience 10 1727-1738

Kern TS (2007) Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy. Experimental Diabetes Research 2007 95013

Kerr BJ, Girolami EI, Ghasemlou N, Jeong SY and David S (2008) The protective effects of 15-deoxy-Delta-(12,14)-prostaglandin J(2) in spinal cord injury. Glia 56 436-448

Kerr C (2002) Curry ingredient protects skin against radiation. Lancet Oncology 3 713

Kerr L (1992) Hot papers – Molecular Biology – The Rel-associated pp40 protein prevents DNA binding of Rel and NF-kB: relationship with IkBb and regulation by phosphorylation by Kerr LD, Inoue JI, Davis N, Link E et al. Scientist 6 15

Kerr LD and Verma IM (1992) cRel and NFkB cooperate to regulate cellular proliferation in B lymphocytes. Journal of Cellular Biochemistry Supplement 16B 225

Kerr LD, Duckett CS, Wamsley P, Zhang Q, Chiao P, Nabel G, McKeithan TW, Baeuerle PA and Verma IM (1992) The proto-oncogene BCL-3 encodes an IkB protein. Genes & Development 6 2352-2363

Kerr LD, Inoue J-I, Davis N, Link E, Baeuerle PA, Bose Jr HR and Verma IM (1991) The Rel-associated pp40 protein prevents DNA binding of Rel and NF-kB: relationship with IkBb and regulation by phosphorylation. Genes & Development 5 1464-1476

Kerr LD, Ransone LJ, Wamsley P, Schmitt MJ, Boyer TG, Zhou Q, Berk AJ and Verma IM (1993) Association between proto-oncoprotein Rel and TATA-binding protein mediates activation by NF-kB. Nature 365 412-419

Kerry S, Tekippe M, Gaddis NC and Aballay A (2006) GATA transcription factor required for immunity to bacterial and fungal pathogens. PLoS ONE 1 e77

Kerschan-Schindl K, Wendlova J, Kudlacek S, Gleiss A, Woloszczuk W and Peitschmann P (2007) Serum levels of receptor activator of nuclear factor kB ligand (RANKL) in healthy women and men. Experimental and Clinical Endocrinology and Diabetes in press

Kersse K, Berghe TV, Lamkanfi M and Vandenabeele P (2007) A phylogenetic and functional overview of inflammatory caspases and caspase-1-related CARD-only proteins. Biochemical Society Transactions 35 1508-1511

Kerstan A and Hunig T (2004) Distinct TCR- and CD28-derived signals regulate CD95L, Bcl-x(L), and the survival of primary T cells. Journal of Immunology 172 1341-1345

Kerzic PJ, Pyatt DW, Zheng JH, Gross SA, Le A and Irons RD (2003) Inhibition of NF-kB by hydroquinone sensitizes human bone marrow progenitor cells to TNF-alpha-induced apoptosis. Toxicology 187 127-137

Keshamouni VG, Arenberg DA, Reddy RC, Newstead MJ, Anthwal S and Standiford TJ (2005) PPAR-gamma activation inhibits angiogenesis by blocking ELR+CXC chemokine production in non-small cell lung cancer. Neoplasia 7 294-301

Keslacy S, Tliba O, Baidouri H and Amrani Y (2006) Inhibition of TNFa-inducible inflammatory genes by IFNg is associated with altered NF-kB transactivation and enhanced HDAC activity. Molecular Pharmacology in press

Kessel A, Bishara R, Amital A, Bamberger E, Sabo E, Grushko G and Toubi E (2005) Increased plasma levels of matrix metalloproteinase-9 are associated with the severity of chronic urticaria. Clinical and Experimental Allergy 35 221-225

Kessel A, Rosner I, Rozenbaum M, Zisman D, Sagiv A, Shmuel Z, Sabo E and Toubi E (2004) Increased CD8+ T cell apoptosis in scleroderma is associated with low levels of NF-kB. Journal of Clinical Immunology 24 30-36

Kessler DJ, Duyao MP, Spicer DB and Sonenshein GE (1992) NF-kB-like factors mediate interleukin 1 induction of c-myc gene transcription in fibroblasts. Journal of Experimental Medicine 176 787-792

Kessler DJ, Spicer DB, La Rosa FA and Sonenshein GE (1992) A novel NF-kB element within exon 1 of the murine c-myc gene. Oncogene 7 2447-2453

Kesson AM and King NJ (2001) Transcriptional regulation of major histocompatibility complex class I by flavivirus West Nile is dependent on NF-kB activation. Journal of Infectious Diseases 184 947-954

Kettritz R, Choi M, Rolle S, Wellner M and Luft FC (2004) Integrins and cytokines activate NF-kB in human neutrophils. Journal of Biological Chemistry 279 2657-2665

Kettritz R, Choi M, Salanova B, Wellner M, Rolle S and Luft FC (2006) Fever-like temperatures affect neutrophil NF-kB signaling, apoptosis, and ANCA-antigen expression. Journal of the American Society of Nephrology in press

Keulen JK, Timmers L, van Kuijk LP, Retnam L, Hoefer IE, Pasterkamp G, Lim SK and de Kleijn DP (2008) The nuclear factor-kB p50 subunit is involved in flow-induced outward arterial remodeling. Atherosclerosis in press

Keum YS, Han SS, Chun KS, Park KK, Park JH, Lee SK, Surh YJ (2003) Inhibitory effects of the ginsenoside Rg(3) on phorbol ester-induced cyclooxygenase-2 expression, NF-kB activation and tumor promotion. Mutation Research 523-524 75-85

Keum YS, Jeong WS and Kong AN (2004) Chemoprevention by isothiocyanates and their underlying molecular signaling mechanisms. Mutation Research 555 191-202

Keum YS, Jeong WS and Kong AN (2005) Chemopreventive functions of isothiocyanates.Drug News Perspect 18 445-452

Keutgens A, Robert I, Viatour P and Chariot A (2006) Deregulated NF-kB activity in haematological malignancies. Biochemical Pharmacology 72 1069-1080

Kfoury Y, Nasr R, Favre-Bonvin A, El-Sabban M, Renault N, Gifron ML, Setterblad N, Hajj HE, Chiari E, Mikati AG, Hermine O, Saib A, de The H, PIque C and Bazarabachi A (2007) Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome.Oncogene in press

Kfoury Y, Nasr R, Hermine O, de The H and Bazarbachi A (2005) Proapoptotic regimes for HTLV-I-transformed cells: targeting Tax and the NF-kB pathway. Cell Death and Differentiation 12 871-877

Khadaroo RG, He R, Parodo J, Powers KA, Marshall JC, Kapus A and Rotstein OD (2004) The role of the Src family of tyrosine kinases after oxidant-induced lung injury in vivo. Surgery 136 483-488

Khadaroo RG, Kapus A, Powers KA, Cybulsky MI, Marshall JC and Rotstein OD (2003) Oxidative stress reprograms LPS signaling via Src kinase-dependent pathway in RAW 264.7 macrophage cell line. Journal of Biological Chemistry 278 47834-47841

Khadaroo RG, Parodo J, Powers KA, Papia G, Marshall JC, Kapus A and Rotstein OD (2003) Oxidant-induced priming of the macrophage involves activation of p38 mitogen-activated protein kinase through an Src-dependent pathway. Surgery 134 242-246

Khadeer MA, Sahu SN, Bai G, Abdulla S and Gupta A (2005) Expression of the zinc transporter ZIP1 in osteoclasts. Bone 37 296-304

Khaled AR, Butfiloski EJ, Sobel ES and Schiffenbauer J (1998) Functional consequences of the SHP-1 defect in motheaten viable mice: role of NF-kB. Cellular Immunology 185 49-58

Khaled AR, Butfiloski EJ, Villas B, Sobel ES and Schiffenbauer J (1999) Aberrant expression of the NF-kB and IkB proteins in B cells from viable motheaten mice. Autoimmunity 30 115-128

Khaled Z, Benimetskaya L, Zeltser R, Khan T, Sharma HW, Narayanan R and Stein CA (1996) Multiple mechanisms may contribute to the cellular anti-adhesive effects of phosphorothioate oligodeoxynucleotides. Nucleic Acids Research 24 737-745

Khan AA, Martin S adn Saha B (2008) SEB-induced signaling in macrophages leads to biphasic TNF-a. Journal of Leukocyte Biology in press

Khan E and Abu-Amer Y (2003) Activation of peroxisome proliferator-activated receptor-gamma inhibits differentiation of preosteoblasts. Lab Clin Med 142 29-34

Khan G (2006) Epstein-Barr virus, cytokines, and inflammation: A cocktail for the pathogenesis of Hodgkin’s lymphoma? Experimental Hematology 34 399-406

Khan M, Sekhon B, Giri S, Jatana M, Gilg AG, Ayasolla K, Elango C, Singh AK and Singh I (2005) S-Nitrosoglutathione reduces inflammation and protects brain against focal cerebral ischemia in a rat model of experimental stroke. Journal of Cerebral Blood Flow and Metabolism 25 177-192

Khan MA, Kang J and Steiner TS (2004) Enteroaggregative Escherichia coli flagellin-induced interleukin-8 secretion requires Toll-like receptor 5-dependent p38 MAP kinase activation. Immunology 112 651-660

Khan MA, Ma C, Knodler LA, Valdez Y, Rosenberger CM, Deng W, Finaly BB and Vallance BA (2006) Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice. Infection and Immunity 74 2522-2536

Khan MN and Khan AA (2008) Cancer treatment-related bone loss: a review and synthesis of the literature. Current Oncology 15 S30-S40

Khan MZ, Brandimarti R, Patel JP, Huynh N, Wang J, Huang Z, Fatatis A and Meucci O (2004) Apoptotic and antiapoptotic effects of CXCR4: is it a matter of intrinsic efficacy? Implications for HIV neuropathogenesis. AIDS Research and Human Retroviruses 20 1063-1071

Khan N, Alam K, Mande SC, Valluri VL, Hasnain SE and Mukhopadhyay S (2008) Mycobacterium tuberculosis heat shock protein 60 modulates immune response to PPD by manipulating the surface expression of TLR2 on macrophages. Cellular Microbiology in press

Khan N, Ghousunnissa S, Jegadeeswaran SM, Thiagarajan D, Hasnain SE and Mukhopadhyay S (2007) Anti-B7-1/B7-2 antibody elicits innate-effector responses in macrophages through NF-kB-dependent pathway. International Immunology 19 477-486

Khan N, Hadi N, Afaq F, Syed DN, Kweon MH and Mukhtar H (2006) Pomegranate fruit extract inhibits prosurvival pathways in human A549 lung carcinoma cells and tumor growth in athymic nude mice. Carcinogenesis in press

Khan N, Rahim SS, Boddupalli CS, Ghousunnissa S, Padma S, Pathak N, Thiagarajan D, Hasnain SE and Mukhopadhyay S (2006) Hydrogen peroxide inhibits IL-12 p40 induction in macrophages by inhibiting c-Rel translocation to the nucleus through activation of calmodulin protein. Blood 107 1513-1520

Khan SA, Lopez-Chua CA, Zhang J, Fisher LW, Sorensen ES and Denhardt DT (2002) Soluble osteopontin inhibits apoptosis of adherent endothelial cells deprived of growth factors. Journal of Cellular Biochemistry 85 728-736

Khan ZA and Chakrabarti S (2007) Cellular signaling and potential new treatment targets in diabetic retinopathy. Experimental Diabetes Research 2007 31867

Khanbolooki S, Nawrocki ST, Arumugam T, Andtbacka R, Pino MS, Kurzrock R, Logsdon CD, Abbruzzese JL and McConkey DJ (2006) Nuclear factor-kB maintains TRAIL resistance in human pancreatic cancer cells. Molecular Cancer Therapy 5 2251-2260

Khanna AK, Plummer M, Nilakantan V and Pieper GM (2005) Recombinant p21 protein inhibits lymphocyte proliferation and transcription factors. Journal of Immunology174 7610-7617

Khanna D, Sethi G, Ahn KS, Pandey MK, Kunnamakkara AB, Sung B, Aggarwal A and Aggarwal BB (2007) Natural products as a gold mine for arthritis treatment. CurrentOpinion in Pharmacology in press

Khanna N, Sen S, Sharma H and Singh N (2003) S29 ribosomal protein induces apoptosis in H520 cells and sensitizes them to chemotherapy. Biochemical and Biophysical Research Communications 304 26-35

Khapli SM, Mangashetti LS, Yogesha SD and Wani MR (2003) IL-3 acts directly on osteoclast precursors and irreversibly inhibits receptor activator of NF-kB ligand-induced osteoclast differentiation by diverting the cells to macrophage lineage. Journal of Immunology 171 142-151

Kharroubi AE, Piras G, Zensen R and Martin MA (1998) Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter. Molecular and Cellular Biology 18 2535-2544

Kharroubi I, Ladriere L, Cardozo AK, Dogusan Z, Cnop M and Eizirik DL (2004) Free fatty acids and cytokines induce pancreatic b-cell apoptosis by different mechanisms: role of NF-kB and endoplasmic reticulum stress. Endocrinology 145 5087-5096

Kharroubi I, Lee CH, Hekerman P, Darville MI, Evans RM, Eizirik DL and Cnop M (2006)BCL-6: a possible missing link for anti-inflammatory PPAR-delta signalling in pancreatic beta cells. Diabetologia 49 2350-2358

Khatri M and Sharma JM (2006) Infectious bursal disease virus infection induces macrophage activation via p38 MAPK and NF-kB pathways. Virus Research 118 70-77

Khayrullina T, Yen JH, Jing H and Ganea D (2008) In vitro differentiation of dendritic cells in the presence of prostaglandin E2 alters the IL-12/IL-23 balance and promotes differentiation of Th17 cells. Journal of Immunology 181 721-735

Khera T, Martin J, Riley S, Steadman R and Phillips AO (2007) Glucose enhances mesangial cell apoptosis. Laboratory Investigation 87 690-701

Kheradmand F, Werner E, Tremble P, Symons M and Werb Z (1998) Role of Rac-1 and oxygen radicals in collagenase-1 expression induced by cell shape change. Science 280 898-902

Khil LY, Kim W, Lyu S, Park WB, Yoon JW and Jun HS (2007) Mechanisms involved in Korean mistletoe lectin-induced apopotsos of cancer cells. World Journal of Gastroenterology 13 2811-2818

Khong T, Sharkey J and Spencer A (2008) The effect of azacitidine on interleukin-6 signaling and nuclear factor-kB activation and its in vitro and in vivo activity against multiple myeloma. Haematologica in press

Khoshnan A, Ko J, Watkin EE, Paige LA, Reinhart PH and Patterson PH (2004) Activation of the IkB kinase complex and nuclear factor-kB contributes to mutant Huntingtin neurotoxicity. Journal of  Neuroscience 24 7999-8008

Khoshnan A, Tindell C, Laux I, Bae D, Bennett B and Nel AE (2000) The NF-kB cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes. Journal of Immunology 165 1743-1754

Khoury J, Ibla JC, Neish AS and Colgan SP (2007) Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation. Journal of ClinicalInvestigation in press

Khoury M, Adiraansen J, Vervoordeldonk MJ, Gould D, Chernajovsky Y, Bigey P, Blaoquel C, Scherman D, Tak PP, Jorgensen C and Apparailly F (2007) Inflammation-inducible anti-TNF gene expression mediated by intra-articular injection of serotype 5 adeno-associated virus reduces arthritis. Journal of Gene Medicine in press

Khursigara G, Bertin J, Yano H, Moffett H, DiStefano PS and Chao MV (2001) A prosurvival function for the p75 receptor death domain mediated via the caspase recruitment domain receptor-interacting protein 2. Journal of Neuroscience 21 5854-5863

Khursigara G, Orlinick JR and Chao MV (1999) Association of the p75 neurotrophin receptor with TRAF6. Journal of Biological Chemistry 274 2597-2600

Khush RS, Cornwell WD, Uram JN and Lemaitre B (2002) A ubiquitin-proteasome pathway represses the Drosophila immune deficiency signaling cascade. Current Biology 12 1728-1737

Khush RS, Leulier F and Lemaitre B (2002) Pathogen surveillance–the flies have it. Science 296 273-275
Khush RS, Leulier F and Lemaitre B (2001) Drosophila immunity: two paths to NF-kB. Trends in Immunology 22 260-264

Khvalevsky E, Rivkin L, Rachmilewitz J, Galun E and Giladi H (2007) TLR3 signaling in a hepatoma cell line is skewed towards apoptosis. Journal of CellularBiochemistry in press

Khwaja A (1999) Akt is more than just a Bad kinase. Nature 401 33-34

Ki SH, Choi MJ, Lee CH and Kim SG (2007) Galpha 12 specifically regulates COX-2 induction by sphingosine 1-phosphate: role for JNK-dependent ubiquitination and degradation of IkBa. Journal of Biological Chemistry 282 1938-1947

Kibbe MR, Johnnides C, Gleixner S, Kovesdi I, Lizonova A, Zuckerbraun B, Billiar TR, Tzeng E and Muluk SC (2003) Regulation of tissue factor expression in smooth muscle cells with nitric oxide. Journal of Vascular Surgery 37 650-659

Kida Y, Higashimoto Y, Inoue H, Shimizu T and Kuwano K (2008) A novel secreted protease from Pseudomonas aeruginosa activates NF-kB through protease-activated receptors. Cellular Microbiology in press

Kida Y, Inoue H, Shimizu T and Kuwano K (2006) Serratia marcescens serralysin induces inflammatory responses through protease-activated receptor-2. Infection &Immunity in press

Kida Y, Kobayashi M, Suzuki T, Takeshita A, Okamatsu Y, Hanazawa S, Yasui T and Hasegawa K (2005) Interleukin-1 stimulates cytokines, prostaglandin E(2) and matrix metalloproteinase-1 production via activation of MAPK/AP-1 and NF-kB in human gingival fibroblasts. Cytokine 29 159-168

Kidd S (1992) Characterization of the Drosophila cactus locus and analysis of interactions between cactus and dorsal proteins. Cell 71 623-635

Kido J, Kido R, Suryono, Kataoka M, Fagerhol MK and Nagata T (2003) Calprotectin release from human neutrophils is induced by Porphyromonas gingivalis lipopolysaccharide via the CD-14-Toll-like receptor-nuclear factor kB pathway. Journal of Periodontal Research 38 557-563

Kido S, Inoue D, Hiura K, Javier W, Ito Y and Matsumoto T (2003) Expression of RANK is dependent upon differentiation into the macrophage/osteoclast lineage: induction by 1alpha,25-dihydroxyvitamin D(3) and TPA in a human myelomonocytic cell line, HL60. Bone 32 621-629

Kiechl S, Werner P, Knoflach M, Furtner M, Willeit J and Schett G (2006) The osteoprotegerin/RANK/RANKL system: a bone key to vascular disease. Expert Revew ofCardiovascular Therapy 4 801-811

Kiechl S, Wiedermann CJ and Willeit J (2003) Toll-like receptor 4 and atherogenesis. Annals of Medicine 35 164-171

Kiechle FL and Zhang X (2002) Apoptosis: biochemical aspects and clinical implications. Clinica Chim Acta 326 27-45

Kiefmann R, Heckel K, Doerger M, Schenkat S, Kupatt C, Stoeckelhuber M, Wesierska-Gadek J and Goetz AE (2004) Role of PARP on iNOS pathway during endotoxin-induced acute lung injury. Intensive Care Medicine 30 1421-1431

Kielar ML, Jeyarajah DR, Penfield JG, Lu CY (2000) Docosahexaenoic acid decreases IRF-1 mRNA and thus inhibits activation of both the IRF-E and NFkB response elements of the iNOS promoter. Transplantation 69 2131-2137

Kiemer AK, Hartung T, Huber C and Vollmar AM (2003) Phyllanthus amarus has anti-inflammatory potential by inhibition of iNOS, COX-2, and cytokines via the NF-kB pathway. Journal of Hepatology 38 289-297

Kiemer AK, Weber NC, Vollmar AM (2002) Induction of IkB: atrial natriuretic peptide as a regulator of the NF-B pathway. Biochemical and Biophysical Research Communications 295 1068-1076

Kieran M, Blank V, Logeat F, Vandekerckhove J, Lottspeich F, Le Bail O, Urban MB, Kourilsky P, Baeuerle PA and Israël A (1990) The DNA binding subunit of NF-kB is identical to factor KBF1 and homologous to the rel oncogene product. Cell 62 1007-1018

Kiernan RE, Bres V, Ng RW, Coudart MP, El Messaoudi S, Sardet C, Jin DY, Emiliani S and Benkirane M (2002) Post-activation turn-off of NF-kB-dependent transcription is regulated by acetylation of p65. Journal of Biological Chemistry 278 2758-2766

Kiesel J, Miller C, Abu-Amer Y and Aurora R (2007) Systems level analysis of osteoclastogenesis reveals intrinsic and extrinsic regulatory interactions.Developmental Dynamics in press

Kieser A, Kaiser C and Hammerschmidt W (1999) LMP1 signal transduction differs substantially from TNF receptor 1 signaling in the molecular functions of TRADD and TRAF2. EMBO Journal 18 2511-2521

Kijima I, Ye J Glackin C and Chen S (2008) CCAAT/enhancer binding protein delta up-regulates aromatase promoters I.3/II in breast cancer epithelial cells. Cancer Research 68 4455-4464

Kikuchi E, Horiguchi Y, Nakashima J, Kuroda K, Oya M, Ohigashi T, Takahashi N, Shima Y, Umezawa K and Murai M (2003) Suppression of hormone-refractory prostate cancer by a novel nuclear factor kB inhibitor in nude mice. Cancer Research 63 107-110

Kikuchi H, Katsuramaki T, Kukita K, Taketani S, Meguro M, Nagayama M, Isobe M, Mizuguchi T and Hirata K (2007) New strategy for the antifibrotic therapy with oral administration of FR260330 (a selective inducible nitric oxide synthase inhibitor) in rat experimental liver cirrhosis. Wound Repair and Regeneration 15 881-888

Kikuchi H, Ozaki T, Furuya K, Hanamoto T, Nakanishi M, Yamamoto H, Yoshida K, Todo S and Nakagawara A (2006) NF-kB regulates the stability and activity of p73 by inducing its proteolytic degradation through a ubiquitin-dependent proteasome pathway. Oncogene in press

Kikuchi T, Hagiwara K, Honda Y, Gomi K, Kobayashi T, Takahashi H, Tokue Y, Watanabe A and Nukiwa T (2002) Clarithromycin suppresses lipopolysaccharide-induced interleukin-8 production by human monocytes through AP-1 and NF-kB transcription factors. Journal of Antimicrobial Chemotherapy 49 745-755

Kikuchi T, Mitani A and Noguchi T (2006) The mechanism of bone resorption in chronic inflammation of periodontal disease [Article in Japanese]. Clinical Calcium 16 241-247

Kikuchi T, Yoshikai Y, Miyoshi J, Katsuki M, Musikacharoen T, Mitani A, Tanaka S, Noguchi T and Matsuguchi T (2003) Cot/Tpl2 is essential for RANKL induction by Lipid A in osteoblasts. Journal of Dental Research 82 546-550

Kikuchi Y, Imakiire T, Hyodo T, Kushiyama T, Higashi K, Hyodo N, SUzuki S and Miura S (2005) Advanced glycation end-product induces fractalkine gene upregulation in normal rat glomeruli. Nephrology, Dialysis and Transplantation 20 2690-2696

Kikumori T, Kambe F, Nagaya T, Funahashi H and Seo H (2001) Thyrotropin modifies activation of nuclear factor kB by tumour necrosis factor alpha in rat thyroid cell line. Biochemical Journal 354 573-579

Kikuno N, Shina H, Urakami S, Kawamoto K, Hirata H, Tanaka Y, Majid S, Igawa M and Dahiya R (2008) Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. International Journal of Cancer in press

Kikuno N, Shina H, Urakami S, Kawamoto K, Hirata H, Tanaka Y, Place RF, Pookot D, Majid S, Igawa M and Dahiya R (2007) Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity. Oncogene in press

Kikuta K, Masamune A, Satoh M, Suzuki N and Shimosegawa T (2004) 4-hydroxy-2, 3-nonenal activates activator protein-1 and mitogen-activated protein kinases in rat pancreatic stellate cells. World Journal of Gastroenterology 10 2344-2351

Kil IS, Kim SY and Park JW (2008) Glutathionylation regulates IkB. Biochemical and Biophysical Research Communications in press

Kil JS, Kim MG, Choi HM, Lim JP, Boo Y, Kim EH, Kim JB, Kim HK and Leem KH (2008) Inhibitory effects of Angelicae Gigantis Radix on osteoclast formation. Phytotherapy Research 22 472-476

Kilcline C, Shinkai K, Bree A, Modica R, Von Scheven E and Frieden IJ (2005) Neonatal-onset multisystem inflammatory disorder: the emerging role of pyrin genes in autoinflammatory diseases. Archives of Dermatology 141 248-253

Killedar SY, Eckenrode SE, McIndoe RA, She JX, Nguyen CQ, Peck AB and Cha SR (2006) Early pathogenic events associated with Sjogren’s syndrome (SjS)-like disease of the nod mouse using microarray analysis. Laboratory Investigation in press

Killeen ME, Englert JA, Beer Stoltz D, Song M, Han y, Delude RL, Kellum JA and Fink MP (2005) The phase 2 enzyme inducers, ethacrynic acid, DL-sulforaphane and oltipraz, inhibit LPS-induced HMGB1 secretion by RAW 264.7 cells. Journal ofPharmacology and Experimental Therapeutics 316 1070-1079

Kilpatrick LE, Lee JY, Haines KM, Campbell DE, Sullivan KE and Korchak HM (2002) A role for PKC-delta and PI 3-kinase in TNF-a-mediated antiapoptotic signaling in the human neutrophil. American Journal of Physiology: Cell Physiology 283 C48-C57

Kilpatrick LE, Sun S and Korchak HM (2004) Selective regulation by {delta}-PKC and PI 3-kinase in the assembly of the anti-apoptotic TNFR-1 signaling complex in neutrophils. American Journal of Physiology: Cell Physiology 287 C633-C642

Kilpinen S and Hurme M (1998) Low CD3+CD28-induced interleukin-2 production correlates with decreased reactive oxygen intermediate formation in neonatal T cells. Immunology 94 167-172

Kim A, Oh JH, Park JM and Chung AS (2007) Methylselenol generated from selenomethionine by methioninase downregulates integrin expression and induces caspase-mediated apoptosis of B16F10 melanoma cells. Journal of Cellular Physiology212 386-400

Kim AJ, Kim YO, Shim JS and Hwang JK (2007) Immunostimulating activity of crude polysaccharide extract isolated from Curcuma xanthorrhiza Roxb. Bioscience,Biotechnology and Biochemistry 71 1428-1438

Kim AR, Cho JY, Lee JY, Choi JS and Chung HY (2005) Hydroquinone modulates reactivity of peroxynitrite and nitric oxide production. Journal of Pharmacy and Pharmacology 57 475-482

Kim AR, Cho JY, Zou Y, Choi JS and Chung HY (2005) Flavonoids differentially modulate nitric oxide production pathways in lipopolysaccharide-activated RAW264.7 cells. Archives of Pharmacal Research 28 297-304

Kim BE, Roh SR, Kim JW, Jeong SW and Kim IK (2003) Cytochrome C-dependent Fas-independent apoptotic pathway in HeLa cells induced by (12)-prostaglandin J(2). Experimental Molecular Medicine 35 290-300

Kim BH, Cho SM, Reddy AM, Kim YS, Min KR and Kim Y (2005) Down-regulatory effect of quercitrin gallate on nuclear factor-kB-dependent inducible nitric oxide synthase expression in lipopolysaccharide-stimulated macrophages RAW 264.7. Biochemical Pharmacology 69 1577-1583

Kim BH, Lee IJ, Lee HY, Han SB, Hong JT, Ahn B, Lee Ck and Kim Y (2007) Quercetin 3-O-beta-(2”-galloyl)-glucopyranoside inhibits endotoxin LPS-induced IL-6 expression and NF-kB activation in macrophages. Cytokine in press

Kim BH, Lee JY, Seo JH, Lee HY, Ryu SY, Ahn BW, Lee CK, Hwang BY, Han SB and Kim Y (20070 Artemisolide is a typical inhibitor of IkB kinase beta targeting cysteine-179 residue and down-regulates NF-kB-dependent TNF-a expression in LPS-activated macrophages.
Biochemical and Biophysical Research Communications in press

Kim BH, Reddy AM, Lee KH, Chung EY, Cho SM, Lee H, Min KR and Kim Y (2004) Inhibitory mechanism of chroman compound on LPS-induced nitric oxide production and nuclear factor-kB activation. Biochemical and Biophysical Research Communications 325 223-228

Kim BH, Roh E, Lee HY, Lee IJ, Ahn B, Jung SH, Lee H, Han SB and Kim Y (2008) Benzoxathiole derivative blocks lipopolysaccharide-induced nuclear factor-kB activation and nuclear factor-kB-regulated gene transcription through inactivating inhibitory kB kinase b. Molecular Pharmacology in press

Kim BH, Shin HM, Jung SH, Yoon YG, Min KR and Kim Y (2005) Anti-inflammatory benzene diamine compound inhibited Toll-like receptor 4-mediated inducible nitric oxide synthase expression and nuclear factor-kB activation. Biol Pharm Bull 28 908-911

Kim BJ, Kim MS, Kim KB, Kim KW, Hong YM, Kim IK, Lee HW and Jung YK (2002) Sensitizing effects of cadmium on TNF-a- and TRAIL-mediated apoptosis of NIH3T3 cells with distinct expression patterns of p53. Carcinogenesis 23 1411-1417

Kim BY, Kang DO, Oh WK, Kim JH, Choi YK, Jang JS, Suh PG, Ryu SH, Mheen TI and Ahn JS (2000) Involvement of SH2-SH2-SH3 domain of phospholipase cgamma1 in NF-kB signaling. FEBS Letters 472 45-49

Kim BY, Kim KA, Kwon O, Kim SO, Kim MS, Kim BS, Oh WK, Kim KD, Jung M and Ahn JS (2005) NF-kB inhibition radiosensitizes Ki-Ras-transformed cells to ionizing radiation. Carcinogenesis 26 1395-1403

Kim B-Y, Gaynor RB, Song K, Dritschilo A and Jung M (2002) Constitutive activation of NF-kB in Ki-ras-transformed prostate epithelial cells. Oncogene 21 4490-4497

Kim CD, Kim YK, Lee SH and Hong KW (2000) Rebamipide inhibits neutrophil adhesion to hypoxia/reoxygenation-stimulated endothelial cells via nuclear factor-kB-dependent pathway. Journal of Pharmacology and Experimental Therapeutics 294 864-869

Kim CH, Kim JH, Hsu CY and Ahn YS (1999) Zinc is required in pyrrolidine dithiocarbamate inhibition of NF-kB activation. FEBS Letters 449 28-32

Kim CH, Kim JH, Lee J and Ahn YS (2003) Zinc-induced NF-kB inhibition can be modulated by changes in the intracellular metallothionein level. Toxicology and Applied Pharmacology 190 189-196

Kim CH, Kim JH, Lee J, Hsu CY and Ahn YS (2003) Thiol antioxidant reversal of pyrrolidine dithiocarbamate-induced reciprocal regulation of AP-1 and NF-kB. Biology and Chemistry 384 143-150

Kim CH, Kim JH, Moon SJ, Chung KC, Hsu CY, Seo JT and Ahn YS (1999) Pyrithione, a zinc ionophore, inhibits NF-kB activation. Biochemical and Biophysical Research Communications 259 505-509

Kim CH, Kim JH, Moon SJ, Hsu CY, Seo JT and Ahn YS (2000) Biphasic effects of dithiocarbamates on the activity of nuclear factor-kB. European Journal of Pharmacology 392 133-136

Kim CH, Lee KH, Lee CT, Kim YW, Han SK, Shim YS and Yoo CG (2003) Aggregation of {beta}2 integrins activates human neutrophils through the IkB/NF-kB pathway. Journal of Leukocyte Biology 75 286-292

Kim CH and Moon SK (2005) Epigallocatechin-3-gallate causes the p21/WAF1-mediated G(1)-phase arrest of cell cycle and inhibits matrix metalloproteinase-9 expression in TNF-alpha-induced vascular smooth muscle cells. Archives of Biochemistry and Biophysics 435 264-272

Kim CM, Koike K, Saito I, Miyamura T and Jay G (1991) HBx gene of hepatitis B virus induces liver cancer in transgenic mice. Nature 353 317-320

Kim CO, Huh AJ, Kim MS, Chin BS, Han SH, Choi SH, Jeong SJ, Choi HK, Choi JY, Song YG and Kim JM (2008) Hydrogen peroxide induces the production of tumor necrosis factor-a in RAW 264.7 macrophage cells via activation of p38 and stress-activated protein kinase. Schok 30 92-97

Kim CS, Kawada T, Kim BS, Han IS, Choe SY, Kurata T and Yu R (2003) Capsaicin exhibits anti-inflammatory property by inhibiting IkB-a degradation in LPS-stimulated peritoneal macrophages. Cell Signaling 15 299-306

Kim D, Kim S, Koh H, Yoon SO, Chung AS, Cho KS and Chung J (2001) Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production. FASEB Journal 15 1953-1962

Kim D, Xu M, Nie L, Peng XC, Jimi E, Voll RE, Nguyen T, Ghosh S and Sun XH (2002) Helix-loop-helix proteins regulate pre-TCR and TCR signaling through modulation of Rel/NF-kB activities. Immunity 16 9-21

Kim DC, Kim SH, Jeong MW, Baek NI and Kim KT (2005) Effect of rottlerin, a PKC-delta inhibitor, on TLR-4-dependent activation of murine microglia. Biochemical and Biophysical Research Communications 337 110-115

Kim DH, Kim JY, Yu BP and Chung HY (2007) The activation of NF-kB through Akt-induced FOXO1 phosphorylation during aging and its modulation by calorie restriction. Biogerontology in press

Kim DH, Kim CH, Kim MS, Kim JY, Jung KJ, Chung JH, An WG, Lee JW, Yu BP and Chung HY 2007) Suppression of age-related inflammatory NF-kB activation by cinnamaldehyde.Biogerontology in press

Kim DH, Kim HK, Park S, Kim JY, Zou Y, Cho KH, Kim YS, Kim DH, Yu BP, Choi JS and Chung HY (2006) Short-term feeding of baicalin inhibits age-associated NF-kB activation. Mechanisms of Ageing and Development in press

Kim DJ, Koh J, Lee O, Kim NJ, Lee YS, Kim YS, Park JY, Lee Ku and Kim GS (2006) Homocysteine enhances apoptosis in human bone marrow stromal cells. Bone in press

Kim DK, Cho ES, Lee BR and Um HD (2001) NF-kB mediates the adaptation of human U937 cells to hydrogen peroxide. Free Radiccal Biology and Medicine 30 563-571

Kim DM, Koo SY, Jeon K, Kim MH, Lee J, Hong CY and Jeong S (2003) Rapid induction of apoptosis by combination of flavopiridol and tumor necrosis factor (TNF)-alpha or TNF-related apoptosis-inducing ligand in human cancer cell lines. Cancer Research 63 621-626

Kim DS, Ho Han J and Kwon HJ (2003) NF-kB and c-Jun-dependent regulation of macrophage inflammatory protein-2 gene expression in response to lipopolysaccharide in RAW 264.7 cells. Molecular Immunology 40 633-643

Kim DS, Jang YJ, Jeon OH and Kim DS (2007) Saxatilin inhibits TNF-a-induced proliferation by suppressing AP-1-dependent IL-8 expression in the ovarian cancer cell line MDAH 2774. Molecular Immunology 44 1409-1416

Kim DS, Park SS, Nam BH, Kim IH and Kim SY (2006) Reversal of drug resistance in breast cancer cells by transglutaminase 2 inhibition and nuclear factor-kB inactivation. Cancer Research 66 10936-10943

Kim DS, Woo ER, Chae SW, Ha KC, Lee Gh, Hong ST, Kwon DY, Kim MS, Jung YK, Kim HM, Kim HK, Kim HR and Chae HJ (2006) Plantainoside D protects adriamycin-induced apoptosis in H9c2 cardiac muscle cells via the inhibition of ROS generation and NF-kB activation. Life Sciences in press

Kim DW, Gazourian L, Quadri SA, Romieu-Mourez R, Sherr DH and Sonenshein GE (2000) The RelA NF-kB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c-myc promoter in mammary cells. Oncogene 19 5498-5506

Kim DW, Lenzen G, Page AL, Legrain P, Sansonetti PJ and Parsot C (2005) The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymes. Proceedings of the National Academy of Sciences USA 102 14046-14051

Kim DW, Sovak MA, Zanieski G, Nonet G, Romieu-Mourez R, Lau AW, Hafer LJ, Yaswen P, Stampfer M, Rogers AE, Russo J and Sonenshein GE (2000) Activation of NF-kB/Rel occurs early during neoplastic transformation of mammary cells. Carcinogenesis 21 871-879

Kim DY, Ryu SY, Lim JE, Lee YS and ro JY (2006) Anti-inflammatory mechanism of simvastatin in mouse allergic asthma model. European Journal of Pharmacology in press

Kim DY, Takeuchi K, Ishinaga H, Kishioka C, Suzuki S, Basbaum C and Majima Y (2004) Roxithromycin suppresses mucin gene expression in epithelial cells. Pharmacology 72 6-11

Kim E, Kang BY and Kim TS (2005) Inhibition of interleukin-12 production in mouse macrophages by hydroquinone, a reactive metabolite of benzene, via suppression of nuclear factor-kB binding activity. Immunology Letters 99 24-29

Kim E, Kim SH, Kim S and Kim TS (2006) The novel cytokine p43 induces IL-12 production in macrophages via NF-kB activation, leading to enhanced IFN-g production in CD4+ T cells. Journal of Immunology 176 256-264

Kim EH and Surh YJ (2006) 15-Deoxy-delta12,14-prostaglandin J2 as a potential endogenous regulator of redox-sensitive transcription factors. BiochemicalPharmacology in press

Kim EJ, Jin HK, Kim YK, Lee HY, Lee SY, Lee KR, Zee OP, Han JW and Lee HW (2001) Suppression by a sesquiterpene lactone from Carpesium divaricatum of inducible nitric oxide synthase by inhibiting nuclear factor-kB activation. Biochemical Pharmacology 61 903-910

Kim EJ, Kwon KJ, Park JY, Lee SH, Moon CH and Baik EJ (2002) Effects of peroxisome proliferator-activated receptor agonists on LPS- induced neuronal death in mixed cortical neurons: associated with iNOS and COX-2. Brain Research 941 1-10

Kim EK, Kim EY, Moon PD, Um JY, Kim HM, Lee HS, Sohn Y, Park SK, Jung HS and Sohn NW (2007) Lithospermi radix extract inhibits histamine release and production of inflammatory cytokine in mast cells. Biosciennce, Biotechnology and Biochemistry in press

Kim EK, Kwon KB, Han MJ, Song MY, Lee JH, Lv N, Choi KB, Ryu DG, Kim KS, Park JW and Park BH (2007) Inhibitory effect of Artemisia capillaris extract on cytokine-induced nitric oxide formation and cytotoxicity of RINm5F cells. International Journal of Molecular Medicine 19 535-540

Kim EK, Kwon KB, Han MJ, Song MY, Lee JH, Lv N, Ka SO, Yeom SR, Kwon YD, Ryu DG, Kim KS, Park JW, Park R and Park BH (2007) Coptidis rhizoma extract protects against cytokine-induced death of pancreatic beta-cells through suppression of NF-kB activation.
Experimental & Molecular Medicine 39 149-159

Kim EK, Kwon KB, Lee JH, Park BH, Park JW, Lee HK, Jhee EC and Yang JY (2007) Inhibition of cytokine-mediated nitric oxide synthase expression in rat insulinoma cells by scoparone. Biological and Pharmaceutical Bulletin 30 242-246

Kim EK, Kwon KB, Shin BC, Seo EA, Lee YR, Kim JS, Park JW, Park BH and Ryu DG (2005) Scopoletin induces apoptosis in human promyeloleukemic cells, accompanied by activations of nuclear factor kB and caspase-3. Life Sciences 77 824-836

Kim EK, Kwon KB, Song MY, Han MJ, Lee JH, Lee YR, Lee JH, Ryu DG, Park BH and Park JW (2007) Flavonoids protect against cytokine-induced pancreatic beta-cell damage through suppression of nuclear factor kappaB activation. Pancrease 35 e1-e9

Kim EY and Teh HS (2004) Critical role of TNF receptor type-2 (p75) as a costimulator for IL-2 induction and T cell survival: a functional link to CD28. Journal of Immunology 173 4500-4509

Kim F, Pham M, Luttrell I, Bannerman DD, Tupper J, Thaler J, Hawn TR, Raines EW and Schwartz MW (2007) Toll like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity. Circulation Research in press

Kim F, Tysseling KA, Rice J, Pham M, Haji L, Gallis BM, Baas AS, Paramsothy P, Giachelli CM, Corson MA and Raines EW (2005) Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKbeta. Arteriosclerosis, Thrombosis and Vascular Biology 25 989-994

Kim GM, Xu J, Song SK, Yan P, Ku G, Xu XM and Hsu CY (2001) Tumor necrosis factor receptor deletion reduces nuclear factor-kB activation, cellular inhibitor of apoptosis protein 2 expression, and functional recovery after traumatic spinal cord injury. Journal of Neuroscience 21 6617-6625

Kim GY, Han MG, Song YS, Shin BC, Shin YI, Lee HJ, Moon DO, Lee CM, Kwak JY, Bae YS, Lee JD and Park YM (2004) Proteoglycan isolated from Phellinus linteus induces Toll-like receptors 2- and 4-mediated maturation of murine dendritic cells via activation of ERK, p38, and NF-kB. Biol Pharm Bull 27 1656-1662

Kim GY, Kim JH, Ahn SC, Lee HJ, Moon DO, Lee CM and Park YM (2004) Lycopene suppresses the lipopolysaccharide-induced phenotypic and functional maturation of murine dendritic cells through inhibition of mitogen-activated protein kinases and nuclear factor-kB. Immunology 113 203-211

Kim GY, Kim KH, Lee SH, Yoon MS, Lee HJ, Moon DO, Lee CM, Ahn SC, Park YC and Park YM (2005) Curcumin inhibits immunostimulatory function of dendritic cells: MAPKs and translocation of NF-kB as potential targets. Journal of Immunology 174 8116-8124

Kim H (2005) Oxidative stress in Helicobacter pylori-induced gastric cell injury. Inflammopharmacology 13 63-74

Kim H (2006) DNA repair Ku proteins in gastric cancer cells and pancreatic acinar cells. Amino Acids in press

Kim H, Chung H,Kim HJ, Lee JY, Oh MY,Kim Y and Kong G (2007) Id-1 regulates Bcl-2 and Bax expression through p53 and NF-kB in MCF-7 breast cancer cells. Breast Cancer Research and Treatment in press

Kim H, Hwang JS, Woo CH, Kim EY, Kim TH, Choo KJ, Kim JH, Seo JM and Lee SS (2008) TNF-a-induced up-regulation of intercellular adhesion molecule-1 is regulated by a Rac-ROS-dependent cascade in human airway epithelial cells. Experimental and Molecular Medicine 40 167-175

Kim H, Kim BY, Soh JW, Cho EJ, Liu JO and Youn HD (2006) A novel function of Nur77: Physical and functional association with protein kinase C. Biochemical andBiophysical Research Communications in press

Kim H, Kim YN, Kim H and Kim CW (2005) Oxidative stress attenuates Fas-mediated apoptosis in Jurkat T cell line through Bfl-1 induction. Oncogene 24 1252-1261

Kim H, Kim YS, Kim SY and Suk K (2001) The plant flavonoid wogonin suppresses death of activated C6 rat glial cells by inhibiting nitric oxide production. Neuroscience Letters 309 67-71

Kim H, Lee YH, Won J and Yun Y (2001) Through induction of juxtaposition and tyrosine kinase activity of Jak1, X-gene product of hepatitis B virus stimulates Ras and the transcriptional activation through AP-1, NF-kB, and SRE enhancers. Biochemical and Biophysical Research Communications 286 886-894

Kim H, Rhee SH, Pothoulakis C and Lamont JT (2007) Inflammation and apoptosis in Clostridium difficile enteritis is mediated by PGE(2) up-regulation of Fas ligand.Gastroenterology 133 875-886

Kim H, Seo JY and Kim KH (1999) Effects of mannitol and dimethylthiourea on helicobacter pylori-induced IL-8 production in gastric epithelial cells. Pharmacology 59 201-211

Kim H, Seo JY and Kim KH (2000) Inhibition of lipid peroxidation, NF-kB activation and IL-8 production by rebamipide in Helicobacter pylori-stimulated gastric epithelial cells. Dig Dis Sci 45 621-628

Kim H, Yang E, Lee J, Kim SH, Shin JS, Park JY, Choi SJ, Kim SJ and Choi IH (2008) Double-stranded RNA mediates interferon regulatory factor 3 activation and interleukin-6 production by engaging Toll-like receptor 3 in human brain astrocytes. Immunology in press

Kim H, Yi JW, Sung YH, Kim CJ, Kim CS and Kang JM (2008) Delayed preconditioning effect of isoflurane on spinal cord ischemia in rats. Neuroscience Letters in press

Kim HA, Kim SH, Ko HM, Choi JH, Kim KJ, Oh SH, Cho KO, CHoi IW and Im SY (2008) Nitric oxide plays a key role in the platelet-activating factor-induced enhancement of resistance against systemic candidiasis. Immunology in press

Kim HA, Lee KB and Bae SC (2005) The mechanism of low-concentration sodium nitroprusside-mediated protection of chondrocyte death. Arthritis Research and Therapy 7 R526-R535

Kim HA, Cho ML, Choi HY, Yoon CS, Jhun JY, Oh HJ and Kim HY (2006) The catabolic pathway mediated by Toll-like receptors in human osteoarthritic chondrocytes.Arthritis and Rheumatism 54 2152-2163

Kim HA and Song YW (2002) TNF-a-mediated apoptosis in chondrocytes sensitized by MG132 or actinomycin D. Biochemical and Biophysical Research Communications 295 937-944

Kim HB, Lee KH, Chung EY, Chang YS, Lee H, Lee CK, Min KR and Kim Y (2006)Inhibitory effect of chroman carboxamide on interleukin-6 expression in response to lipopolysaccharide by preventing nuclear factor-kB activation in macrophages.European Jounral of Pharmacology 543 158-165

Kim HE, Choi SE, Lee SJ, Lee JH, Lee YJ, Kang SS, Chun J and Kang Y (2008) TNFa-induced GSIS inhibition in INS-1 cells is ascribed to a reduction of the glucose-stimulated Ca2+ influx. Journal of Endocrinology in press

Kim HG, Kimm NR, Gim MG, Lee JM, Lee SY, Ko MY, Kim JY, Han SH and Chung DK (2008) Lipoteichoic acid isolated from Lactobacillus plantarum inhibits lipopolysaccharide-induced TNF-a production in THP-1 cells and endotoxin shock in mice. Journal of Immunology 180 2553-2561

Kim HG, Lee SY, Kim NR, Ko MY, Lee JM, Yi TH, Chung SK and Chung DK (2008) Inhibitory effects of Lactobacillus plantarum lipoteichoic acid (LTA) on Staphylococcus aureus LTA-induced tumor necrosis factor-a production. Journal of Miicrobiology and Technology 18 1191-1196

Kim HG, Shrestha B, Lim SY, Yoon DH, Chang WC, Shin DJ, Han SK, Park SM, Park JH, Park HI, Sung JM, Jang Y, Chung N, Hwang KC and Kim TW (2006) Cordycepin inhibits lipopolysaccharide-induced inflammation by the suppression of NF-kB through Akt and p38 inhibition in RAW 264.7 macrophage cells. European Journal of Pharmacology 545 192-199

Kim HG, Yoon DH, Kim CH, Shrestha B, Chang WC, Lim SY, Lee WH, Han SG, Lee JO, Lim MH, Kim GY, Choi S, Song WO, Sung JM, Hwang KC and Kim TW (2007) Ethanol extract of Inonotus obliquus inhibits lipopolysaccharide-induced inflammation in RAW 264.7 macrophage cells. Journal of Medicinal Food 10 80-89

Kim HG, Yoon DH, Lee WH, Han SK, Shretha B, Kim CH, Lim MH, Chang W, Lim S, CHoi S, Song WO, Sung JM, Hwang KC and Kim TW (2007) Phellinus linteus inhibits inflammatory mediators by suppressing redox-based NF-kB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophage. Journal of Ethnopharmacology in press

Kim HH (1999) Characterization of the NF-kB activation induced by TR8, an osteoclastogenic tumor necrosis factor receptor family member. Archives of Pharmacal Research 22 454-458

Kim HH, Kim JH, Kwak HB, Huang H, Han SH, Ha H, Lee SW, Woo ER and Lee ZH (2004) Inhibition of osteoclast differentiation and bone resorption by tanshinone IIA isolated from Salvia miltiorrhiza Bunge. Biochemical Pharmacology 67 1647-1656

Kim HH, Lee Y, Eun HC and Chung JH (2008) Eicosapentaenoic acid inhibits TNF-a-induced matrix metalloproteinase-9 expression in human keratinocytes, HaCaT cells. Biochemical and Biophysical Research Communications in press

Kim HJ, Byun SJ and Kim TY (2004) Differential regulation of IGF-II-induced IL-8 by extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinases in human keratinocytes. Biochemical and Biophysical Research Communications 317 276-284

Kim HJ, Chang EJ, Kim HM, Lee SB, Kim HD, Su Kim G and Kim HH (2006) Antioxidant a-lipoic acid inhibits osteoclast differentiation by reducing nuclear factor-kB DNA binding and prevents in vivo bone resorption induced by receptor activator of nuclear factor-kB ligand and tumor necrosis factor-a. Free Radical Biology and Medicine 40 1483-1493

Kim HJ, Hawke N and Baldwin AS (2006) NF-kB and IKK as therapeutic targets in cancer. Cell Death and Differentiation in press

Kim HJ, Jung KJ, Yu BP, Cho CG, Choi JS and Chung HY (2002) Modulation of redox-sensitive transcription factors by calorie restriction during aging. Mechanisms of Ageing and Development 123 1589-1595

Kim HJ, Kim HY, Kim BK, Kim S and Chung DH (2006) Engagement of glucocorticoid-induced TNF receptor costimuates NKT cell activation in vitro and in vivo. Journal of Immunology 176 3507-3515

Kim HJ, Kim KW, Yu BP and Chung HY (2000) The effect of age on cyclooxygenase-2 gene expression: NF-kB activation and IkBa degradation. Free Radical Biology and Medicine 28 683-692

Kim HJ, Lee HS, Chong YH and Kang JL (2006) p38 mitogen-activated protein kinase up-regulates LPS-induced NF-kB activation in the development of lung injury and RAW 264.7 macrophages. Toxicology 225 36-47

Kim HJ, Lee Y, Chang EJ, Kim HM, Hong SP, Lee ZH, Ryu J and Kim HH (2007) Suppression of osteoclastogenesis by N,N-dimethyl-D-erythro-sphingosine:  a sphingosine kinase inhibition-independent action. Molecular Pharmacology in press

Kim HJ, Litzenburger BC, Cui X, Delgado DA, Grabiner BC, Lin X, Lewis MT, Gottardis MM, Wong TW, Attar RM, Carboni J and Lee AV (2007) Constitutively active IGF-IR causes transformation and xenograft growth of immortalized mammary epithelial cells, and is accompanied by an epithelial to mesenchymal transition mediated by NF-kB and Snail. Molecular and Cellular Biology in press

Kim HJ, Park JK and Kim YG (1999) Suppression of NF-kB activation in normal T cells by supernatant fluid from human renal cell carcinomas. Journal of Korean Medical Sciences 14 299-303

Kim HJ, Park KG, Yoo EK, Kim YH, Kim YN, Kim HS, Kim HT, Park JY, Lee KU, Jang WG,Kim JG, Kim BW and Lee IK (2007) Effects of PGC-1alpha on TNF-alpha-induced MCP-1 and VCAM-1 expression and NF-kB activation in human aortic smooth muscle and endothelial cells. Antioxidant and Redox Signaling in press

Kim HJ, So HS, Lee JH, Park C, Lee JB, Youn MJ, Kim SJ, Yang SH, Lee KM, Kwon KB, Park BH and Park R (2008) Role of proinflammatory cytokines in cisplatin-induced vestibular hair cell damage. Head and Neck in press

Kim HK, Kim JE, Chung J, Kim YT, Kang Sh, Han SH and Cho HI (2007) Lipopolysaccharide down-regulates the thrombomodulin expression of peripheral blood monocytes: effect of serum on thrombomodulin expression in the THP-1 monocytic cell line. Blood Coagulation & Fibrinolysis 18 157-164

Kim HK, Park HR, Lee JS, Chung TS, Chung HY and CHung J (2007) Down-regulation of iNOS and TNF-a expression by kaempferol via NF-kB inactivation in aged rat gingival tissues. Biogerontology in press

Kim HS, Lee YK, Kim JW, Baik SK, Kwon SO and Jang HI (2006) Modulation of colon cancer cell invasiveness induced by deoxycholic aci [Article in Korean]. Korean Journal of Gastroenterology 48 9-18

Kim HS, Loughran PA, Kim PK, Billiar TR and Zuckerbraun BS (2006) Carbon monoxide protects hepatocytes from TNF-a/actinomycin D by inhibition of the caspase-8-mediated apoptotic pathway.
Biochemical and Biophysical Research Communications 344 1172-1178

Kim HS, Loughran P, Rao J, Billiar TR and Zuckerbraun BS (2008) Carbon monoxide activates NF-kB via ROS generation and Akt Pathways to protect against cell death Of hepatocytes. American Journal of Physiology: Gastrointestinal and Liver Physiology in press

Kim HY and Kim HS (2006) Upregulation of MIP-2 (CXCL2) expression by 15-deoxy-Delta(12,14)-prostaglandin J(2) in mouse peritoneal macrophages. Immunology and Cell Biology in press

Kim HY, Rho YH, Choi SJ, Lee YH, Cheon HJ, Um JW, Sohn J, Song GG and Ji JD (2005) 15-Deoxy-delta(12,14)-PGJ(2)inhibits IL-6-induced Stat3 phosphorylation in lymphocytes. Experimental and Molecular Medicine 37 179-185

Kim HJ, Yu BP and Chung HY (2002) Molecular exploration of age-related NF-kB/IKK downregulation by calorie restriction in rat kidney. Free Radical Biology and Medicine 32 991-1005

Kim HJ, Tsoy I, Heo JM, Kang YJ, Park MK, Lee YS, Lee JH, Seo HG, Yun-Choi HS and Chang KC (2006) Regulation of lipopolysaccharide-induced inducible nitric oxide synthase expression through nuclear factor-kB pathway and IFN-{beta}/Tyk2/JAK2-STAT-1 signaling cascades by 2-naphtylethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (THI 53), a new synthetic isoquinoline alkaloid. Journal of Pharmacology andExperimental Therapeutics in press

Kim HJ, Tsoy I, Park JM, Chung JI, Shin SC and Chang KC (2006) Anthocyanins from soybean seed coat inhibit the expression of TNF-a-induced genes associated with ischemia/reperfusion in endothelial cell by NF-kB-dependent pathway and reduce rat myocardial damages incurred by ischemia and reperfusion in vivo.
FEBS Letters 580 1391-1397

Kim HK, Park HR, Sul KH, Chung HY and Chnung J (2006) Induction of RANTES and CCR5 through NF-kB activation via MAPK pathway in aged rat gingival tissues.Biotechnology Letters 28 17-23

Kim HM, Bae SJ, Kim DW, Kim BK, Lee SB, Lee US, Kim CH and Moon SK (2007) Inhibitory role of magnolol on proliferative capacity and matrix metalloproteinase-9 expression in TNF-alpha-induced vascular smooth muscle cells. International Immunopharmacology 7 1083-1091

Kim HR, Cho ML, Kim KW, Juhn JY, Hwang SY, Yoon CH, Park Sh, Lee SH and Kim HY (2006) Up-regulation of IL-23p19 expression in rheumatoid arthritis synovial fibroblasts by IL-17 through PI3-kinase-, NF-kB- and p38 MAPK-dependent signalling pathways. Rheumatology (Oxford) 46 57-64

Kim HR, Kim S, Kim EJ, Park JH, Yang SH, Jeong ET, Park C, Youn MJ, So HS and Park R (2007) Suppression of Nrf2-driven heme oxygenase-1 enhances the chemosensitivity of lung cancer A549 cells toward cisplatin. Lung Cancer in press

Kim HS, Chang I, Kim JY, Choi KH and Lee MS (2005) Caspase-mediated p65 cleavage promotes TRAIL-induced apoptosis. Cancer Research 65 6111-6119

Kim HS, Kim HJ, Park KG, Kim YN, Kwon TK, Park JY, Lee KU, Kim JG and Lee IK (2007) alpha-Lipoic acid inhibits matrix metalloproteinase-9 expression by inhibiting NF-kB transcriptional activity. Experimental & Molecular Medicine 39 106-113

Kim HS, Kim S and Lee MS (2005) IFN-g sensitizes MIN6N8 insulinoma cells to TNF-a-induced apoptosis by inhibiting NF-kB-mediated XIAP upregulation. Biochemical and Biophysical Research Communications 336 847-853

Kim HS, Oh JM, KJIn DH, Yang KH and Moon EY (2008) Paclitaxel induces vascular endothelial growth factor expression through reactive oxygen species production. Pharmacology 81 317-324

Kim HY, Kim JR and Kim HS (2008) Upregulation of lipopolysaccharide-induced interleukin-10 by prostaglandin A1 in mouse peritoneal macrophages. Journal of Microbiology and Biotechnology 18 1170-1178

Kim HS, Wang SY, Woo MS, Park JS, Kim WK and Han IO (2004) Sodium butyrate suppresses interferon-gamma-, but not lipopolysaccharide-mediated induction of nitric oxide and tumor necrosis factor-alpha in microglia. Journal of Neuroimmunology 151 85-93

Kim HY, Kang YJ, Song IH, Choi HC and Kim HS (2008) Upregulation of interleukin-8/CXCL8 in vascular smooth muscle cells from spontaneously hypertensive rats. Hypertension Research 31 515-523

Kim HY, Kim HK, Kim JR and Kim HS (2005) Upregulation of LPS-induced chemokine KC expression by 15-deoxy-Delta-prostaglandin J in mouse peritoneal macrophages.Immunol Cell Biol 83 286-293

Kim HY and Rikihisa Y (2002) Roles of p38 Mitogen-Activated Protein Kinase, NF-kB, and Protein Kinase C in Proinflammatory Cytokine mRNA Expression by Human Peripheral Blood Leukocytes, Monocytes, and Neutrophils in Response to Anaplasma phagocytophila. Infection & Immunity 70 4132-4141

Kim I, Kim JH, Ryu YS, Liu M and Koh GY (2000) Tumor necrosis factor-alpha upregulates angiopoietin-2 in human umbilical vein endothelial cells. Biochemical and Biophysical Research Communications 269 361-365

Kim I, Moon SO, Kim SH, Kim HJ, Koh YS and Koh GY (2001) VEGF stimulates expression of ICAM-1, VCAM-1 and E-selectin through nuclear factor-kB activation in endothelial cells. Journal of Biological Chemistry 276 7614-7620

Kim I, Oh JL, Ryu YS, So JN, Sessa WC, Walsh K and Koh GY (2002) Angiopoietin-1 negatively regulates expression and activity of tissue factor in endothelial cells. FASEB Journal 16 126-128

Kim IS, Kim JH, Kim JS, Yun CY, Kim DH and Lee JS (2007) The inhibitory effect of Houttuynia cordata extract on stem cell factor-induced HMC-1 cell migration. Journal of Ethnopharmacology in press

Kim IK, Li CC, Young HA, Lee JH, Kim HS, Pardhasaradhi K, Garcia GE, Chiang PK (1997) Apoptosis of L1210 leukemia cells induced by 3-deazaadenosine analogs: differential expression of c-myc, NF-kB and molecular events. Journal of Biomedical Sciences 4 83-90

Kim IT, Park HJ, Nam JH, Park YM, Won JH, Choi J, Choe BK and Lee KT (2005) In-vitro and in-vivo anti-inflammatory and antinociceptive effects of the methanol extract of the roots of Morinda officinalis. Journal of Pharmacy and Pharmacology 57 607-616

Kim IT, Park YM, Won JH, Jung HJ, Park HJ, Choi JW and Lee KT (2005) Methanol extract of Xanthium strumarium L. possesses anti-inflammatory and anti-nociceptive activities. Biol Pharm Bull 28 94-100

Kim J (2005) Review of the innate immune response in Acne vulgaris: activation of Toll-like receptor 2 in acne triggers inflammatory cytokine responses. Dermatology211 193-198

Kim J, Bates DG, Postlethwaite I, Heslop-Harrison P and Cho KH (2007)  Least-squares methods for identifying biochemical regulatory networks from noisy measurements. BMC Bioinformatics 8 8

Kim J, Hwang JS, Cho YK, Han Y, Jeon YJ and Yang KH (2001) Protective effects of (-)-epigallocatechin-3-gallate on UVA- and UVB-induced skin damage. Skin Pharmacology and Applied Skin Physiology 14 11-19

Kim J, Kim C and Kim-Ha J (2006) Ovarian tumors in Rbp9 mutants of Drosophila induce an immune response. Molecules and Cells 22 228-232

Kim J, Kim H, Jeun S, Rha S, Kim Y, Ko Y, Won J, Lee K, Rha H and Wang Y (2002) Inhibition of NF-kB activation by merlin. Biochemical and Biophysical Research Communications 296 1295-1302
Kim J, Kim HR, Bae J, Kim DH, Kim HJ, Lee HK and Choi SH (2004) Cross-linking of MHC class II molecules with anti-MHC class II antibody or epitope peptide prevents resting B lymphocyte differentiation by inhibiting NF-kB-dependent gene expression. Molecules and Cells 12 67-76

Kim J and Kim-Ha J (2006) Ovarian tumors in rbp9 mutants of Drosophila induce and immune response. Molecules and Cells 22 228-232

Kim J, Lee H, Oh BG, Cho C, Kim Y, Shin M, Hong M, Jung SK and Bae H (2007) Inhibition effects of Moutan Cortex Radicis on secretion of eotaxin in A549 human epithelial cells and eosinophil migration.
Journal of Ethnopharmacology in press

Kim J, Nam KH, Kim SO, Choi JH, Kim HC, Yang SD, Kang JH, Ryu YH, Oh GT and Yoo SE (2004) KR-31378 ameliorates atherosclerosis by blocking monocyte recruitment in hypercholestrolemic mice. FASEB Journal 18 714-716

Kim J, Ochoa MT, Krutzik SR, Takeuchi O, Uematsu S, Legaspi AJ, Brightbill HD, Holland D, Cunliffe WJ, Akira S, Sieling PA, Godowski PJ and Modlin RL (2002)Activation of Toll-like receptor 2 in acne triggers inflammatory cytokine responses. Journal of Immunology 169 1535-1541

Kim J, Sanders SP, Siekierski ES, Casolaro V and Proud D (2000) Role of NF-kB in cytokine production induced from human airway epithelial cells by rhinovirus infection. Journal of Immunology 165 3384-3392

Kim J, Shao Y, Kim SY, Kim S, Song HK, Jeon JH, Woo Suh H, Chung JW, Yoon SR, Kim YS and Choi I (2007) Hypoxia-induced IL-18 increases hypoxia-inducible factor-1alpha expression through a Rac1-dependent NF-kB pathway. Molecular Biology of the Cell in press

Kim J, Son JW, Lee JA, Oh YS and Shinn SH (2004) Methylglyoxal induces apoptosis mediated by reactive oxygen species in bovine retinal pericytes. Korean Journal of Medical Science 19 95-100

Kim JA, Kim DK, Jin Tae, Kang OH, Choi YA, Choi SC, Kim TH, Nah YH, Choi SJ, Kim YH, Bae KH and Lee YM (2004) Acanthoic acid inhibits IL-8 production via MAPKs and NF-kB in a TNF-alpha-stimulated human intestinal epithelial cell line. Clinica Chimica Acta 342 193-202

Kim JA, Kim DK, Kang OH, Choi YA, Park HJ, Choi SC, Kim TH, Yun KJ, Nah YH and Lee YM (2005) Inhibitory effect of luteolin on TNF-alpha-induced IL-8 production in human colon epithelial cells. International Immunopharmacology 5 209-217

Kim JA, Tay D and Blanco EC (2008) NF-kB inhibitory activity of compounds isolated from Cantharellus cibarius. Phytotherapy Research in press

Kim JB, Han AR, Park EY, Kim JY, Cho W, Lee J, Seo EK and Lee KT (2007) Inhibition of LPS-induced iNOS, COX-2 and cytokines expression by Poncirin through the NF-kB inactivation in RAW 264.7 macrophage cells. Biological and Pharmacological Bulletin 30 2345-2351

Kim JB, Yu YM, Kim SW and Lee JK (2005) Anti-inflammatory mechanism is involved in ethyl pyruvate-mediated efficacious neuroprotection in the postischemic brain. Brain Research 1060 188-192

Kim JC, Lee SY, Kim SY, Kim JK, Kim HJ, Lee HM, Choi MS, Min JS, Kim MJ, Choi HS and Ahn JK (2008) Regulation of the maturation of osteoblasts and osteoclastogenesis by glutamate. FEBS Letters in press

Kim JD, Choi BK, Bae JS, Lee UH, Han IS, Lee HW, Youn BS, Vinay DS and Kwon BS (2003) Cloning and characterization of GITR ligand. Genes  & Immunity 4 564-569

Kim JG, Kim JH, Lee DO, Kim H, Kim JY, Suh CS, Kim SH and Choi YM (2007) Changes in the serum levels of osteoprotegerin and soluble receptor activator for nuclear factor kappaB ligand after estrogen-progestogen therapy and their relationships with changes in bone mass in postmenopausal women. Menopause in press

Kim JG, Lee SJ and Kagnoff MF (2004) Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors. Infection & Immunity 72 1487-1495

Kim JH, Jung JH, Jeon ST, Kim H, Ock J, Suk K, Kim SI, Song KS and Lee WH (2006) Decursin inhibits induction of inflammatory mediators by blocking NF-kB activation in macrophages. Molecular Pharmacology 69 1783-1790

Kim JH, Kim B, Cai L, Choi HJ, Ohgi KA, Tran C, Chen C, Chung CH, Huber O, Rose DW, Sawyers CL, Rosenfeld MG and Baek SH (2005) Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes. Nature 434 921-926

Kim JH, Kim DH, Baek SH, Lee HJ, Kim MR, Kwon HJ and Lee CH (2006) Rengyolone inhibits inducible nitric oxide synthase expression and nitric oxide production by down-regulation of NF-kB and p38 MAP kinase activity in LPS-stimulated RAW 264.7 cells. Biochemical Pharmacology 71 1198-1205

Kim JH, Kim HN, Lee KT, Lee JK, Choi SH, Paik SW, Rhee JC and Lowe AW (2008) Gene expression profiles in gallbaladder cancer: the close genetic cimilarity seen for earlya nd advanced gallbladder cancers may explain the poor prognosis. Tumour Biology 29 41-49

Kim JH, Kim KY, Jeon JH, Lee SH, Hwang JE, Lee JH, Kim KK, Lim JS, Kim KI, Moon EY, Lee HG, Ryu JH and Yang Y (2008) Adipocyte culture medium stimulates production of macrophage inhibitory cytokine 1 in MDA-MB-231 cells. Cancer Letters 261 253-262

Kim JH, Lee KW, Lee MW, Lee HJ, Kim SH and Surh YJ (2006) Hirsutenone inhibits phorbol ester-induced upregulation of COX-2 and MMP-9 in cultured human mammary epithelial cells: NF-kB as a potential molecular target. FEBS Letters 580 385-392

Kim JH, Na HJ, Kim CK, Kim JY, Ha KS, Lee H, Chung HT, Kwon HJ, Kwon YG and Kim YM (2008) The non-provitamin A carotenoid, lutein, inhibits NF-kB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-kappaB-inducing kinase pathways: Role of H(2)O(2) in NF-kB activation. Free Radical Biology and Medicine in press

Kim JH, Na HK, Pak YK, Lee YS, Lee SJ, Moon A and Surh YJ (2007) Roles of ERK and p38 mitogen-activated protein kinases in phorbol ester-induced NF-kB activation and COX-2 expression in human breast epithelial cells. Chemicao-Biological Interactions in press

Kim JH, Soo Ha I, Hwang CI, Lee YJ, Kim J, Yang SH, Kim YS, Cao YA, Choi S and Park WY (2004) Gene expression profiling of anti-GBM glomerulonephritis model: The role of NF-kB in immune complex kidney disease. Kidney International 66 1826-1837

Kim JH, Xu C, Keum YS, Reddy B, Conney A and Kong AN (2006) Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with beta-phenylethyl isothiocyanate and curcumin. Carcinogeneis 27 475-482

Kim JI, Kin JK, Choi EK, Spinner D, Rubenstein R, Carp RI and Kim YS (2007) Increased expression and localization of cyclooxygenase-2 in astrocytes of scrapie-infected mice. Journal of Neuroimmunology in press

Kim JI, Ju WK, Choi JH, Choi E, Carp RI, Wisniewski HM and Kim YS (1999) Expression of cytokine genes and increased nuclear factor-kB activity in the brains of scrapie-infected mice. Brain Research Molecular Brain Research 73 17-27

Kim JK, Kim KD, Lee E, Lim JS, Cho HJ, Yoon HK, Cho MY, Baek KE, Park YP, Paik SG, Choe YK and Lee HG (2004) Up-regulation of Bfl-1/A1 via NF-kB activation in cisplatin-resistant human bladder cancer cell line. Cancer Letters 212 61-70

Kim JK, Kim Y, Na KM, Surh YJ and Kim TY (2007) [6]-Gingerol prevents UVB-induced ROS production and COX-2 expression in vitro and in vivo. Free Radical Research 41 603-614

Kim JK, Oh SM, Kwon HS, Oh YS, Lim SS and Shin HK (2006) Anti-inflammatory effect of roasted licorice extracts on lipopolysaccharide-induced inflammatory responses in murine macrophages. Biochemical and Biophysical Research Communications 345 1215-1223

Kim JM, Cho SJ, Oh YK, Jung HY and Kim YJ (2002) Nuclear factor-kB activation pathway in intestinal epithelial cells is a major regulator of chemokine gene expression and neutrophil migration induced by Bacteroides fragilis enterotoxin. Clinical and Experimental Immunology 130 59-66

Kim JM, Jeong D, Kang HK, Jung SY, Kang SS and Min BM (2007) Osteoclast precursors display dynamic metabolic shifts toward accelerated glucose metabolism at an early stage of RANKL-stimulated osteoclast differentiation. Cell Physiology and Biochemistry 20 935-946

Kim JM, Kim JS, Jung HC, Oh YK, Chung HY, Lee CH and Song IS (2003) Helicobacter pylori infection activates the NF-kB signaling pathway to induce iNOS and protect human gastric epithelial cells from apoptosis. American Journal of Physiology: Gastrointestintal Liver Physiology 285 G1171-G1180

Kim JM, Kim JS, Jung HC, Oh YK, Kim N and Song IS (2003) Inhibition of Helicobacter pylori-induced Nuclear Factor-kB activation and interleukin-8 gene expression by ecabet sodium in gastric epithelial cells. Heliobacter 8 542-553

Kim JM, Kim JS, Kim YJ, Oh YK, Kim IY, Chee YJ, Han JS and Jung HC (20080 Conjugated linoleic acids produced by Lactobacillus dissociates IKK-gamma and Hsp90 complex in Helicobacter pylori-infected gastric epithelial cells. Laboratory Investigation in press

Kim JM, Lee SU, Kim YS, Min YK and Kim SH (2008) Baicalein stimulates osteoblast differentiation via coordinating activation of MAP kinases and transcription factors. Journal of Cellular Biochemistry in press

Kim JS, Kim JS, Lee JY, Kim YJ, Youn HJ, Kim IY, Chee YJ, Oh YK, Kim N, Jung HC and Song IS (2007) Vacuolating cytotoxin in Helicobacter pylori water-soluble proteins upregulates chemokine expression in human eosinophils via Ca2+ influx, mitochondrial reactive oxygen intermediates, and NF-kB activation. Infection and Immunity in press

Kim JM, Kim NI, Oh YK, Kim YJ, Youn J and Ahn MJ (2005) CpG oligodeoxynucleotides induce IL-8 expression in CD34+ cells via mitogen-activated protein kinase-dependent and NF-kB-independent pathways. International Immunology 17 1525-1531

Kim JM, Lee JY, Yoon YM, Oh YK, Kang JS, Kim YJ and Kim KH (2006) Bacteroides fragilis enterotoxin induces cyclooxygenase-2 and fluid secretion in intestinal epithelial cells through NF-kB activation. European Journal of Immunology 36 2446-2456

Kim JM, Lee JY, Yoon YM, Oh YK, Youn J and Kim YJ (2006) NF-kB activation pathway is essential for the chemokine expression in intestinal epithelial cells stimulated with Clostridium difficile toxin A. Scandinvain Journal of Immunology 63 453-460

Kim JM, Min SK, Kim H, Kang HK, Jung SY, Lee SH, Choi Y, Roh S, Jeong D and Min BM (2007) Vacuolar-type H+-ATPase-mediated acidosis promotes in vitro osteoclastogenesis via modulation of cell migration. International Journal of Molecular Medicine 19 393-400

Kim JM, Oh YK, Kim YJ, Oh HB and Cho YJ (2001) Polarized secretion of CXC chemokines by human intestinal epithelial cells in response to Bacteroides fragilis enterotoxin: NF-kB plays a major role in the regulation of IL-8 expression. Clinical and Experimental Immunology 123 421-427

Kim JM, Oh YK, Kim YJ, Youn J and Ahn MJ (2004) Escherichia coli up-regulates proinflammatory cytokine expression in granulocyte/macrophage lineages of CD34 stem cells via p50 homodimeric NF-kB. Clinical and Experimental Immunology 137 341-350

Kim JM, Oh YK, Lee JH, Im DY, Kim YJ, Youn J, Lee CH, Son H, Lee YS, Park JY and Choi IH (2005) Induction of proinflammatory mediators requires activation of the TRAF, NIK, IKK and NF-kB signal transduction pathway in astrocytes infected with Escherichia coli. Cinical and Experimental Immunology 140 450-460

Kim JO, Kim HW, Baek KM and Kang CY (2003) NF-kappaB and AP-1 regulate activation-dependent CD137 (4-1BB) expression in T cells. FEBS Letters 541 163-170

Kim JS, Lee JM, Chwae YJ, Kim YH, Lee JH, Kim K, Lee TH, Kim SJ and Park JH (2004) Cisplatin-induced apoptosis in Hep3B cells: mitochondria-dependent and -independent pathways. Biochemical Pharmacology 67 1459-1468

Kim JS and Jobin C (2004) Role of NF-kB in inflammatory disorders: just when you thought you knew everything! Journal of Pediatric Gastroenterology and Nutrition 38 109-110

Kim JS and Jobin C (2005) The flavonoid luteolin prevents lipopolysaccharide-induced NF-kB signalling and gene expression by blocking IkB kinase activity in intestinal epithelial cells and bone-marrow derived dendritic cells. Immunology 115 375-387

Kim JS, Kim JM, Jung HC and Song IS (2001) Expression of cyclooxygenase-2 in human neutrophils activated by Helicobacter pylori water-soluble proteins: possible involvement of NF-kB and MAP kinase signaling pathway. Dig Dis Sci 46 2277-2284

Kim JS, Lee HJ, Lee MH, Kim J, Jin C and Ryu JH (2006) Luteolin inhibits LPS-stimulated inducible nitric oxide synthase expression in BV-2 microglial cells.Planta Medica 72 65-68

Kim JS, Narula AS and Jobin C (2005) Salvia miltiorrhiza water-soluble extract, but not its constituent salvianolic acid B, abrogates LPS-induced NF-kB signalling in intestinal epithelial cells. Clinical and Experimental Immunology 141 288-297

Kim JW, Choi EJ and Joe CO (2000) Activation of death-inducing signaling complex (DISC) by pro-apoptotic C-terminal fragment of RIP. Oncogene 19 4491-4499

Kim JW, Joe CO and Choi EJ (2001) Role of receptor-interacting protein in tumor necrosis factor-alpha-dependent MEKK1 activation. Journal of Biological Chemistry 276 27064-27070

Kim JY, Ahn MH, Jun HS, Jung JW, Ryu JS and Min DY (2006) Toxoplasma gondii inhibits apoptosis in infected cells by caspase inactivation and NF-kB activation. Yonsei Medical Journal 47 862-869

Kim JY, Byeon SE, Lee YG, Lee JY, Park J, Hong EK and Cho JY (2008) Immunostimulatory activities of polysaccharides from liquid culture of pine-mushroom Tricholoma matsutake. Journal of Microbiology and Biotechnology 18 95-103

Kim JY, Choi CY, Lee KJ, Shin DW, Jung KS, Chung YC, Lee SS, Shin JG and Jeong HG (2004) Induction of inducible nitric oxide synthase and proinflammatory cytokines expression by o,p’-DDT in macrophages. Toxicology Letters 147 261-269

Kim JY, Jung KJ, Choi JS and Chung HY (2006) Modulation of the age-related nuclear factor-kB (NF-kB) pathway by hesperetin. Aging Cell in press

Kim JY, Kim DH, Kim HG, Song GY, CHung YC, Roh SH and Jeong HG (2005) Inhibition of tumor necrosis factor-a-induced expression of adhesion molecules in human endothelial cells by the saponins derived from roots of Platycodon grandiflorum. Toxicology and Applied Pharmacology 210 150-156

Kim JY, Kim TH and Kim SS (2008) Anti-inflammatory effect of a human prothrombin fragment-2-derived peptide, NSA9, in EOC2 microglia. Biochemical and Biophysical Research Communications in press

Kim JY, Jung KS and Jeong HG (2004) Suppressive effects of the kahweol and cafestol on cyclooxygenase-2 expression in macrophages. FEBS Letters 569 321-326

Kim JY and Kim C (2005) Inhibition of LPS-induced NO production by taurine chloramine in macrophages is mediated through Ras-ERK-NF-kB. Biochemical Pharmacology 70 1352-1360

Kim JY, Kim H, Lee SG, Choi BH, Kim YH, Huh PW, Lee KH, Han H and Rha HK (2003) Amyloid beta peptide (Abeta42) activates PLC-delta1 promoter through the NF-kB binding site. Biochemical and Biophysical Research Communications 310 904-909

Kim JY and Jeong HG (2003) Down-regulation of inducible nitric oxide synthase and tumor necrosis factor-a expression by bisphenol A via nuclear factor-kB inactivation in macrophages. Cancer Letters 196 69-76

Kim JY, Jung KS, Lee KJ, Na HK, Chun HK, Kho YH and Jeong HG (2004) The coffee diterpene kahweol suppress the inducible nitric oxide synthase expression in macrophages. Cancer Letters 213 147-154

Kim JY, Oh KN, Han EH, Kim DH, Jeong TC, Lee ES and Jeong HG (2005) Methoxychlor-induced inducible nitric oxide synthase and proinflammatory cytokines expression in macrophages via NF-kB, ERK, and p38 mitogen-activated protein kinases. Biochemical and Biophysical Research Communications 333 1234-1240

Kim JY, Omori E, Matsumoto K, Nunez G and Ninomiya-Tsuji J (2007) TAK1 is a central mediator of NOD2 signaling in epidermal cells. Journal of Biological Chemistry in press

Kim JY, Park JS, Strassheim D, Douglas I, Diaz Del Valle F, Asehnoune K, Mitra S, Kwak SH, Yamada S, Maruyama I, Ishizaka A and Abraham E (2005) HMGB1 contributes to the development of acute lung injury after hemorrhage. American Joournal of Physiology: Lung Cell and Molecular Physiology 288 L958-L965

Kim JY, Park SJ, Yun KJ, Cho YW, Park HJ and Lee KT (2008) Isoliquiritigenin isolated from the roots of Glycyrrhiza uralensis inhibits LPS-induced iNOS and COX-2 expression via the attenuation of NF-kB in RAW 264.7 macrophages. European Journal of Immunology in press

Kim JY and Ro JY (2005) Signal pathway of cytokines produced by reactive oxygen species generated from phorbol myristate acetate-stimulated HMC-1 cells. Scandinavian Journal of Immunology 62 25-35

Kim JY, Yoon YD, Ahn JM, Kang JS, Park SK, Lee K, Song KB, Kim HM and Han SB (2007) Angelan isolated from Angelica gigas Nakai induces dendritic cell maturation through toll-like receptor 4.
International Immunopharmacology 7 78-87

Kim K, Ryu K, Ko Y and Park C (2005) Effects of nuclear factor-kB inhibitors and its implication on natural killer T-cell lymphoma cells. British Journal of Haematology 131 59-66

Kim KA, Choi SK and Choi HS (2004) Corn silk induces nitric oxide synthase in murine macrophages. Exp Mol Med 36 545-550

Kim KA, Shin HH, Choi SK and Choi HS (2005) Corn silk induced cyclooxygenase-2 in murine macrophages. Biosci Biotechnol Biochem 69 1848-1853

Kim K-E, Gu C, Thakur S, Viera E, Lin JC and Rabson AB (2000) Transcriptional regulatory effects of lymphoma-associated NFKB2/lyt10 protooncogenes. Oncogene 19 1334-1345

Kim KIk Kang JH, Chung JK, Lee YJ, Jeong JM, Lee DS and Lee MC (2007) Doxorubicin enhances the expression of transgene under control of the CMV promoter in anaplastic thyroid carcinoma cells.
Journal of Nuclear Medicine in press

Kim KJ, Myung SJ, Hong SS, Lee YJ, Lee SM, Byeon JS, Yang SK, Hong WS, Kim JH and Min YI (2005) Clinical usefulness of glucocorticoid receptor Beta expression and NF-kB activity in patients with ulcerative colitis [Article in Korean]. Korean Journal of Gastroenterology 45 103-110

Kim KM, Choi JY, Yoo SE, Park MY, Lee BS, Ko YH, Sung SH, Shin HM and Park JE (2007) HMCO5, herbal extract, inhibits NF-kB expression in lipopolysaccharide treated macrophages and reduces atherosclerotic lesions in cholesterol fed mice. Journal ofEthnopharmacology in press

Kim KM, Kim PK, Kwon YG, Bai SK, Nam WD and Kim YM (2002) Regulation of apoptosis by nitrosative stress. Journal of Biochemistry and Molecular Biology 35 127-133

Kim KM, Kwon YG, Chung HT, Yun YG, Pae HO, Han JA, Ha KS, Kim TW and Kim YM (2003) Methanol extract of Cordyceps pruinosa inhibits in vitro and in vivo inflammatory mediators by suppressing NF-kB activation. Toxicology and Applied Pharmacology 190 1-8

Kim KM, Pae HO, Zhang M, Ha HY, Ha YA, Cha KY, Cheong YK, Kim JM and Chung HT (2008) Involvement of anti-inflammatory heme oxygenase-1 in the inhibitory effect of curcumin on the expression of pro-inflammatory inducible nitric oxide synthase in RAW264.7 macrophages. Biomedical Pharmacotherapy in press

Kim KM Song JJ, An JY, Kwon YT and Lee YJ (2005) Pretreatment of acetyl salicylic acid promotes trail-induced apoptosis by downregulating BCL-2 gene expression. Journal of Biological Chemistry 280 41047-41056

Kim KM, Zhang Y, Kim BY, Jeong SJ, Lee SA, Kim GD, Dritschilo A and Jung M (2004) The p65 subunit of nuclear factor-kB is a molecular target for radiation sensitization of human squamous carcinoma cells. Molecular Cancer Therapy 3 693-698

Kim KS, Cho HS, Lee SD, Kim KH, Cho JY, Chung KH, Lee YC, Moon SK and Kim CH (2005) Inhibitory effect of Buthus martensi Karsch extracts on interleukin-1beta-induced expression of nitric oxide (NO) synthase and production of NO in human chondrocytes and LPS-induced NO and prostaglandin E2 production in mouse peritoneal macrophages. Toxicology In Vitro 19 757-769

Kim KS, Park EK, Ju SM, Jung HS, Bang JS, Kim C, Lee YA, Hong SJ, Lee SH, Yang HI and Yoo MC (2007) Taurine chloramine differentially inhibits matrix metalloproteinase 1 and 13 synthesis in interleukin-1beta-stimulated fibroblast-like synoviocytes. Arthritis Research and Therapy 9 R80

Kim KS, Rajagopal V, Gonxalves C, Johnson C and Kalra VK (2006) A novel role of hypoxia-inducible factor in cobalt chloride- and hypoxia-mediated expression of IL-8 chemokine in human endothelial cells. Journal of Immunology 177 7211-7224

Kim KW, Cho ML, Kim HR, Ju JH, Park MK, Oh HJ, Kim JS, Park SH, Lee SH and Kim HY (2007) Up-regulation of stromal cell-derived factor 1 (CXCL12) production in rheumatoid synovial fibroblasts through interactions with T lymphocytes: Role of interleukin-17 and CD40L-CD40 interaction. Arthritis and Rheumatism 56 1076-1086

Kim KW, Cho ML, Park MK, Yoon CH, Park SH, Lee SH and Kim HY (2005) Increased interleukin-17 production via a phosphoinositide 3-kinase/Akt and nuclear factor kB-dependent pathway in patients with rheumatoid arthritis. Arthritis Research and Therapy 7 R139-R148

Kim KW, Kim BJ, Chung CW, Jo DG, Kim IK, Song YH, Kwon YK, Woo HN and Jung YK (2002) Caspase cleavage product lacking amino-terminus of IkBa sensitizes resistant cells to TNF-alpha and TRAIL-induced apoptosis. Journal of Cellular Biochemistry 85 334-345

Kim KY, Kim JK, Han SH, Lim JS, Kim KI, Cho DH, Lee MS, Lee JH, Yoon DY, Yoon SR, Chung JW, Choi I, Kim E and Yang Y (2006) Adiponectin is a negative regulator of NK cell cytotoxicity.
Journal of Immunology 176 5958-5964

Kim LK, Choi UY, Cho HS, Lee JS, Lee WB, Kim J, Jeong K, Shim J, Kim-Ha J and Kim YJ (2007) Down-regulation of NF-kB target genes by the AP-1 and STAT complex during the innate immune response in Drosophila. PLoS Biology 5 e238

Kim MH and Joo HG (2007) Immunostimulatory effects of fucoidan on bone marrow-derived dendritic cells. Immunology Letters in press

Kim M, Lee JH, Lee SY, Kim E and Chung J (2006) Caspar, a suppressor of antibacterial immunity in Drosophila. Proceedings of the National Academy ofSciences USA 103 16358-16363

Kim MH, Kim MO, Heo JS, Kim JS and Han HJ (2007) Acetylcholine inhibits long-term hypoxia-induced apoptosis by suppressing the oxidative stress-mediated MAPKs activation as well as regulation of Bcl-2, c-IAPs, and caspase-3 in mouse embryonic stem cells. Apoptosis in press

Kim MH, Kim BT, Min YK and Kim SH (2006) Profiling signalling pathways of the receptor activator of NF-kB ligand-induced osteoclast formation in mouse monocyte cells, RAW264.7. Amino Acids in press

Kim MH, Lee HY, Roh E, Kim BH, Chung EY, Lee YR, Lee IJ, Lee H, Lee CK, Han SB and Kim Y (2008) Novel iminobenzoxathiolone compound inhibits nuclear factor-kB activation targeting inhibitory kB kinase beta and down-regulating interleukin-1b expression in lipopolysaccharide-activated macrophages. Biochemical Pharmacology in press

Kim MH, Park JS, Chang HJ, Baek MK, Kim HR, Shin BA, Ahn BW and Jung YD (2008)Lysophosphatidic acid promotes cell invasion by up-regulating the urokinase-type plasminogen activator receptor in human gastric cancer cells. Journal of Cellular Biochemistry in press

Kim MH, Yoo HS, Kim MY, Jang JH, Baek MK, Kim HR, Kim KK, Shin BA, Ahn BW and Jung YD (2007) Helicobacter pylori stimulates urokinase plasminogen activator receptor expression and cell invasiveness through reactive oxygen species and NF-kB signaling in human gastric carcinoma cells. International Journal of Molecular Medicine 19 689-697

Kim MJ, Han JM, Jin YY, Baek NI, Bang MH, Chung HG, Choi MS, Lee KT, Sok DE and Jeong TS (2008) In vitro antioxidant and anti-inflammatory activities of Jaceosidin from Artemisia princeps Pampanini cv. Sajabal. Archives of Pharmacal Research 31 429-437

Kim MJ, Kim DH, Lee KW, Yoon DY and Surh YJ (2007) Jaceosidin induces apoptosis in ras-transformed human breast epithelial cells through generation of reactive oxygen species. Annals of the New York Academy of Sciences 1095 483-495

Kim MJ, Kim MK and Kang JS (2006) Orientia tsutsugamushi inhibits tumor necrosis factor alpha production by inducing interleukin 10 secretion in murine macrophages.Microbial Pathogenesis 40 1-7

Kim MJ, Ryu GR, Kang JH, Sim SS, Min do S, Rhie DJ, Yoon SH, Hahn SJ, Jeong IK, Hong KJ, Kim MS and Jo YH (2004) Inhibitory effects of epicatechin on interleukin-1beta-induced inducible nitric oxide synthase expression in RINm5F cells and rat pancreatic islets by down-regulation of NF-kB activation. Biochemical Pharmacology 68 1775-1785

Kim MO, Moon DO, Heo MS, Lee JD, Jung JH, Kim SK, Choi YH and Kim GY (2008) Pectenotoxin-2 abolishes constitutively activated NF-kB, leading to suppression of NF-kB related gene products and potentiation of apoptosis. Cancer Letters in press

Kim MO, Suh HS, Brosnan CF and Lee SC (2004) Regulation of RANTES/CCL5 expression in human astrocytes by interleukin-1 and interferon-beta. Journal of Neurochemistry 90 297-308

Kim MO, Suh HS, Si Q, Terman BI and Lee SC (2006) Anti-CD45RO suppresses human immunodeficiency virus type 1 replication in microglia: role of Hck tyrosine kinase and implications for AIDS dementia. Journal of Virology 80 62-72

Kim MS, Lim WK, Park RK, Sin T, Yoo YH, Hong SH, An NH and Kim HM (2005) Involvement of mitogen-activated protein kinase and NF-kappaB activation in Ca(2+)-induced IL-8 production in human mast cells. Cytokine 32 226-233

Kim MS, Park MJ, Kim SJ, Lee CH, Yoo H, Shin SH, Song ES and Lee SH (2005) Emodin suppresses hyaluronic acid-induced MMP-9 secretion and invasion of glioma cells.International Journal of Oncology 27 839-846

Kim MY, Anderson G, White A, Jenkinson E, Arlt W, Martensson IL, Erlandsson L and Lane PJ (2005) OX40 ligand and CD30 ligand are expressed on adult but not neonatal CD4+CD3- inducer cells: evidence that IL-7 signals regulate CD30 ligand but not OX40 ligand expression. Journal of Immunology 174 6686-6691

Kim MY, Song KS, Park GH, Chang SH, Kim HW, Park JH, Jin H, Eu KJ, Cho HS, Kang G, Kim YC and Cho MH (2004) B6C3F1 mice exposed to ozone with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and/or dibutyl phthalate showed toxicities through alterations of NF-kB, AP-1, Nrf2, and osteopontin. Journal of Veterinary Science 5 131-137

Kim ND, Kim EM, Kang KW, Cho MK, Choi SY and Kim SG (2003) Ginsenoside Rg3 inhibits phenylephrine-induced vascular contraction through induction of nitric oxide synthase. British Journal of Pharmacology 140 661-670

Kim ND, Pokharel YR andKang KW (20070 Ginsenoside Rd enhances glutathione levels in H4IIE cells via NF-kB-dependent gamma-glutamylcysteine ligase induction. Pharmazie 62 933-936

Kim NH, Jeon S, Lee HJ and Lee AY (2007) Impaired PI3K/Akt activation-mediated NF-kB inactivation under elevated TNF-a is more vulnerable to apoptosis in vitiliginous keratinocytes. Journal of Investative Dermatology in press

Kim NS, Kim HJ, Koo BK, Kwon MC, Kim YW, Cho Y, Yokota Y, Penninger JM and Kong YY (2006) Receptor activator of NF-kB ligand regulates the proliferation of mammary epithelial cells via Id2. Molecular and Cellular Biology 26 1002-1013

Kim R, Emi M, Tanabe K and Murakami S (2006) Role of the unfolded protein response in cell death. Apoptosis 11 5-13

Kim R, Emi M, Tanabe K, Uchida Y and Toge T (2004) The role of Fas ligand and transforming growth factor beta in tumor progression. Cancer 100 2281-2291

Kim RD, Darling CE, Cerwenka H and Chari RS (2000) Hypoosmotic stress activates p38, ERK 1 and 2, and SAPK/JNK in rat hepatocytes. Journal of Surgical Research 90 58-66

Kim RD, Roth TP, Darling CE, Ricciardi R, Schaffer BK and Chari RS (2001)  Hypoosmotic stress stimulates growth in HepG2 cells via protein kinase B-dependent activation of activator protein-1. Journal of Gastrointestinal Surgery 5 546-555

Kim RG, Shin KM, Kim YK, Jeong HJ, Ha J, Choi JW, Park HJ, Lee KT (2003) Inhibition of methanol extract from the aerial parts of Saururus chinensis on lipopolysaccharide-induced nitric oxide and prostagladin E(2) production from murine macrophage RAW 264.7 cells. Biol Pharm Bull 26 481-486

Kim S, Choi K, Kwon D, Benveniste EN and Choi C (2004) Ubiquitin-proteasome pathway as a primary defender against TRAIL-mediated cell death. Cell Mol Life Sci 61 1075-1081

Kim S, Domon-Dell C, Kang J, Chung DH, Freund JN, Evers BM (2004) Down-regulation of the tumor suppressor PTEN by the TNFa /NIK/NF-kB pathway is linked to a default IkB-a autoregulatory loop. Journal of Biological Chemistry 274 4285-4291

Kim S, Domon-Dell C, Wang Q, Chung DH, Di Cristofano A, Pandolfi PP, Freund JN and Evers BM (2002) PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kB-dependent pathway. Gastroenterology 123 1163-1178

Kim S, Fotiadu A and Kotoula V (2005) Increased expression of soluble decoy receptor 3 in acutely inflamed intestinal epithelia. Clinical Immunology 115 286-294

Kim S, Johnson V and Sharma R (2002) Mercury inhibits nitric oxide production but activates proinflammatory cytokine expression in murine macrophage: differential modulation of NF-kB and p38 MAPK signaling pathways. Nitric Oxide 7 67-74

Kim S, Kang S, Kim H and Kim T (2002) Potentiation of 1,25-dihydroxyvitamin D(3)-induced differentiation of human promyelocytic leukemia cells into monocytes by costunolide, a germacranolide sesquiterpene lactone. Biochemical Pharmacology 64 1233-1242

Kim S, La Motte-Mohs RN, Rudolph D, Zuniga-Pflucker JC and Mak TW (2003) The role of nuclear factor-kB essential modulator (NEMO) in B cell development and survival. Proceedings of the National Academy of Sciences USA 100 1203-1208

Kim S, Millet I, Kim HS, Kim JY, Han MS, Lee MK, Kim KW, Sherwin RS, Karin M, and Lee MS (2007) NF-kB prevents beta cell death and autoimmune diabetes in NOD mice.Proceedings of the National Academy of Sciences USA in press

Kim S, Salim AA, Swanson SM and Kinghorn AD (2006) Potential of cyclopenta[b]benzofurans from Aglaia species in cancer chemotherapy. Anticancer Agents in Medicinal Chemistry 6 319-345

Kim S, Yamazaki M, Zella LA, Meyer MB, Fretz JA, Shevde NK and Pike JW (2006) Multiple enhancer regions located at significant distances upstream of the transcriptional start site mediate RANKL gene expression in response to 1,25-dihydroxyvitamin D(3). Journal of Steroid Biochemistry and Molecular Biology in press

Kim SB, Kim JS, Lee JH, Yoon WJ, Lee DS, Ko MS, Kwon BS, Choi DH, Cho HR, Lee BJ, Chung DK, Lee HW and Park JW (2006) NF-kB activation is required for cisplatin-induced apoptosis in head and neck squamous carcinoma cells. FEBS Letters 580 311-318

Kim SB, Natori Y, Ozawa T, Umezawa Y and Tao H (2007) A method for determining the activities of cytokines based on the nuclear transport of nuclear factor-kB.Analytical Biochemistry 103 430-434

Kim SC, Tonkonogy SL, Karrasch T, Jobin C and Sartor RB (2007) Dual-association of gnotobiotic Il-10-/- mice with 2 nonpathogenic commensal bacteria induces aggressive pancolitis. Inflammatory Bowel Disease in press

Kim SD, Yang SI, Kim HC, Shin CY and Ko KH (2007) Inhibition of GSK-3beta mediates expression of MMP-9 through ERK1/2 activation and translocation of NF-kB in rat primary astrocyte. Brain Research in press

Kim SG, Cho MK, Choi SH, Kim HJ, Kwak MK and Kim ND (1999) Molecular basis for hepatic detoxifying enzyme induction by 2-(allylthio)pyrazine in rats in comparison with oltipraz: effects on prooxidant production and DNA degradation. Drug Metab Dispos 27 667-673

Kim SG, Kim JS, Kim JM, Jung HC and Song IS (2005) Inhibition of proinflammatory cytokine expression by NF-kB (p65) antisense oligonucleotide in Helicobacter pylori-infected mice. Heliobacter 10 559-566

Kim SH, Choi CH, Kim SY, Eun JS and Shin TY (2005) Anti-allergic effects of Artemisia iwayomogi on mast cell-mediated allergy model. Exp Biol Med (Maywood) 230 82-88

Kim SH, Chu HJ, Kang DH, Song GA, Cho M, Yang US, Kim HJ and Chung HY (2002) NF-kB binding activity and cyclooxygenase-2 expression in persistent CCl(4)-treated rat liver injury. Journal of Korean Medical Science 17 193-200

Kim SH, Gunnery S, Choe JK and Mathews MB (2002) Neoplastic progression in melanoma and colon cancer is associated with increased expression and activity of the interferon-inducible protein kinase, PKR. Oncogene 21 8741-8748

Kim SH, Han SY, Azam T, Yoon DY and Dinarello CA (2005) Interleukin-32: a cytokine and inducer of TNFa. Immunity 22 131-142

Kim SH, Hong KO, Hwang JK and Park KK (2005) Xanthorrhizol has a potential to attenuate the high dose cisplatin-induced nephrotoxicity in mice. Food and Chemical Toxicology 43 117-122

Kim SH, Johnson VJ, Shin TY and Sharma RP (2004) Selenium attenuates lipopolysaccharide-induced oxidative stress responses through modulation of p38 MAPK and NF-kB signaling pathways. Exp Biol Med (Maywood) 229 203-213

Kim SH, Jun CD, Suk K, Choi BJ, Lim H, Park S, Lee SH, Shin HY, Kim DK and Shin TY (2006) Gallic acid inhibits histamine release and pro-inflammatory cytokine production in mast cells. Toxicological Sciences 91 123-131

Kim SH, Kang YJ, Kim WJ, Woo DK, Lee Y, Kim DI, Park YB, Kwon BS, Park JE and Lee WH (2004) TWEAK can induce pro-inflammatory cytokines and matrix metalloproteinase-9 in macrophages. Circulation Journal 68 396-399

Kim SH, Kim TS, Kim SJ, Seong CN, Lee OH, Lee HJ and Yoo JC (2007) Inhibition of interleukin-12 production in mouse macrophages via suppression of nuclear factor-kB binding activity by Phyllostachys nigra var. henonis. Immunopharmacology andImmunotoxicology 29 131-139

Kim SH, Kim TS, Lee JW, Ha JW, Park NS, Lee HJ and Yoo JC (2007) Inhibition of mouse macrophages interleukin-12 production: suppression of nuclear factor-kB binding activity by a specific factor isolated from Scapharca broughtonii. Archives ofPharmacal Research 30 350-354

Kim SH, Kwon TK and Shin TY (2008) Antiallergic effects of vitis amurensis on mast cell-mediated allergy model. Experimental Biology and Medicine (Maywood) 233 192-199

Kim SH, Oh SM and Kim TS (2005) Induction of human leukemia HL-60 cell differentiation via a PKC/ERK pathway by helenalin, a pseudoguainolide sesquiterpene lactone. European Journal of  Pharmacology 511 89-97

Kim SH, Reznikov LL, Stuyt RJ, Selzman CH, Fantuzzi G, Hoshino T, Young HA and Dinarello CA (2001) Functional reconstitution and regulation of IL-18 activity by the IL-18R beta chain. Journal of Immunology 166 148-154

Kim SH, Shin KJ, Kim D, Kim YH, Han MS, Lee TG, Kim E, Ryu SH and Suh PG (2003) Luteolin inhibits the nuclear factor-kB transcriptional activity in Rat-1 fibroblasts. Biochemical Pharmacology 66 955-963

Kim SH and Shin TY (2005) Amomum xanthiodes inhibit mast cell-mediated allergic reactions through the inhibition of histamine release and inflammatory cytokine production. Experimental Biology and Medicine (Maywood) 230 681-687

Kim SH and Shin TY (2005) Effect of Dracocephalum argunense on mast-cell-mediated hypersensitivity. International Archives of Allergy and Immunology 139 87-95

Kim SH, Song JH, Choi BG, Kim HJ and Kim TS (2006) Chemical modification of santonin into a diacetoxy acetal form confers the ability to induce differentiation of human promyelocytic leukemia cells via the downregulation of NF-kB DNA binding activity.Journal of Biological Chemistry 281 13117-13125

Kim SH, Song SH, Kim SG, Chun KS, Lim SY, Na HK, Kim JW, Surh YJ, Bang YJ and Song YS (2004) Celecoxib induces apoptosis in cervical cancer cells independent of cyclooxygenase using NF-kB as a possible target. Journal of Cancer Research and Clinical Oncology 130 551-560

Kim SH, Hwang CI, Juhnn YS, Lee JH, Park WY and SAong YS (2007) GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells. Carcinogenesis 28 223-231

Kim SH, Hwang CI, Park WY, Lee JH and Song YS (2006) GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells. Carcinogenesis 27 1961-1969

Kim SH, Lee S, Suk K, Bark H,Jun CD, Kim DK, Choi CH and Yoshimura T (2007) Discoidin domain receptor 1 mediates collagen-induced nitric oxide production in J774A.1 murine macrophages. Free Radical Biology and Medcine 42 343-352

Kim SJ, Choi EY, Cho YJ, Lee JY, Choi JI and Choi IS (2005) Surface-associated material from Porphyromonas gingivalis stimulates the release of nitric oxide by inducing expression of inducible nitric oxide synthase. Microbes and Infection 8 470-477

Kim SJ and Chun JS (2003) Protein kinase Calpha and zeta regulate nitric oxide-induced NF-kB activation that mediates cyclooxygenase-2 expression and apoptosis but not dedifferentiation in articular chondrocytes. Biochemical and Biophysical Research Communications 303 206-211

Kim SJ, Ha MS, Choi EY, Choi JI and Choi IS (2004) Prevotella intermedia lipopolysaccharide stimulates release of nitric oxide by inducing expression of inducible nitric oxide synthase. Journal of Periodontal Research 39 424-431

Kim SJ, Ha MS, Choi EY, Choi JI and Choi IS (2005) Nitric oxide production and inducible nitric oxide synthase expression induced by Prevotella nigrescens lipopolysaccharide. FEMS Immunol Med Microbiol 43 51-58

Kim SJ, Hwang SG, Kim IC and Chun JS (2003) Actin cytoskeletal architecture regulates nitric oxide-induced apoptosis, dedifferentiation and cyclooxygenase-2 expression in articular chondrocytes via mitogen-activated protein kinase and protein kinase C pathways. Journal of Biological Chemistry 278 42448-42456

Kim SJ, Jeong HJ, Choi IY, Lee KM, Park RK, Hong SH and Kim HM (2005) Cyclooxygenase-2 inhibitor (SC-236) suppresses NF-kB activation and phosphorylation of p38 MAPK, ERK, and JNK in HMC-1 cells. Journal of Pharmacology & Experimental Therapeutics 314 27-34

Kim SJ, Jeong HJ, Lee KM, Moon PC, Yun JM, Cho KM, Moon BS, Lee HJ, Hong SH, Kim HM and Um JY (2006) The effect of SHJKS on cytokines production and NF-kB activation in the peripheral blood mononuclear cells of patients with cerebral infarction.Immunopharmacology and Immunotoxicology 28 557-570

Kim SJ, Jeong HJ, Lee KM, Myung NY, An NH, Yang WM, Park SK, Lee HJ, Hong SH, Kim HM and Um JY (2007) Epigallocatechin-3-gallate suppresses NF-kB activation and phosphorylation of p38 MAPK and JNK in human astrocytoma U373MG cells. Journal ofNutritional Biochemistry in press

Kim SJ, Jeong HJ, Moon PD, Lee KM, Lee HB, Jung HJ, Jung SK, Rhee HK, Yang DC, Hong SH and Kim HM (2005) Anti-inflammatory activity of gumiganghwaltang through the inhibition of nuclear factor-kB activation in peritoneal macrophages. Biological &Pharmaceutical Bulletin 28 233-237

Kim SJ, Jeong HJ, Moon PD, Lee KM, Lee MG, Moon BS, An NH, Hong SH, Na HJ, Jeon H, Kim HM and Um JY (2006) The anti-inflammatory effect of gigukjiwhangwhangami through the inhibition of nuclear factor-kB activation in the peripheral blood mononuclear cells of patients with cerebral infarction. Biological & Pharmaceutical Bulletin 292251-2255

Kim SJ, Jeong HJ, Park SU, Moon BS, Moon PD, An NH, Lee KM, Hong SH, Kim HM and Um JY (2007) Anti-inflammatory effect of Dohongsamultang through inhibition of nuclear factor-kB activation in peripheral blood mononuclear cells of patients with Cerebral infarction. American Journal of Chinese Medcine 35 415-426

Kim SJ, Kang SY, Shin HH and Choi HS (2005) Sulforaphane inhibits osteoclastogenesis by inhibiting nuclear factor-kB. Molecules and  Cells 20 364-370

Kim SJ, Lee EJ, Song YS, Jeong HJ, Lee KM, Kim HR, Chae HJ, Shin TY, Kim YK, Hong SH and Kim HM (2005) Cheongyeolsaseuptang inhibits production of TNF-alpha, IL-6 and IL-8 as well as NF-kB activation in human mast cells. Journal of Ethnopharmacology 97 83-88

Kim SJ, Varghese TK, Zhang Z, Zhao LC, Thomas G, Hummel M and Abecassis M (2005) Renal ischemia/reperfusion injury activates the enhancer domain of the human cytomegalovirus major immediate early promoter. American Journal of Transplantation5 1606-1613

Kim SN, Kim MH, Min YK and Kim SH (2008) Licochalcone A inhibits the formation and bone resorptive activity of osteoclasts. Cell Biology International in press

Kim SN, Son SC, Lee SM, Kim CS, Yoo DG, Lee SK, Hur GM, Park JB and Jeon BH (2006) Midazolam inhibits proinflammatory mediators in the lipopolysaccharide-activated macrophage. Anesthesiology 105 105-110

Kim SO, Chun KS, Kundu JK and Surh YJ (2004) Inhibitory effects of [6]-gingerol on PMA-induced COX-2 expression and activation of NF-kB and p38 MAPK in mouse skin. Biofactors 21 27-31

Kim SO, Kundu JK, Shin YK, Park JH, Cho MH, Kim TY and Surh YJ (2005) [6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-kB in phorbol ester-stimulated mouse skin. Oncogene 24 2558-2567

Kim SP, Park JW, Lee SH, Lim JH, Jang BC, Lee SH, Jang IH, Freund JN, Suh SI, Mun KC, Song DK, Ha EM, Lee WJ and Kwon TK (2004) Homeodomain protein CDX2 regulates COX-2 expression in colorectal cancer. Biochemical and Biophysical Research Communications 315 93-99

Kim SR, Bae YH, Bae SK, Choi SK, Yoon KH, Koo TH, Jang HO, Yun I, Kim KW, Kwon YG, Yoo MA and Bae MK (2008) Visfatin enhances ICAM-1 and VCAM-1 expression through ROS-dependent NF-kB activation in endothelial cells. Biochimica et Biophysica Acta in press

Kim SR, Lee KS, Park SJ, Min KH, Lee KY, Choe YH, Hong SH, Koh GY and Lee YC (2008) Angiopoietin-1 variant, COMP-Ang1 attenuates hydrogen peroxide-induced acute lung injury. Experimental and Molecular Medicine 40 320-331

Kim SR, Lee KS, Park SJ, Min KH, Lee KY, Choe YH, Lee YR, Kim JS, Hong SJ and Lee YC (2007) PTEN down-regulates IL-17 expression in a murine model of toluene diisocyanate-induced airway disease. Journal of Immunology 179 6820-6829

Kim SS, Rhee S, Lee KH, Kim JH, Kim HS, Kang MS and Chung CH (1998) Inhibitors of the proteasome block the myogenic differentiation of rat L6 myoblasts. FEBS Letters 433 47-50

Kim SW, Choi SC, Choi EY, Kim KS, Oh JM, Lee HJ, Oh HM, Kim S, Oh BS, Kimm KC, Lee MH, Seo GS, Kim TH, Oh HC, Woo WH, Kim YS, Pae HO, Park DS, Chung HT and Jun CD (2004) Catalposide, a compound isolated from Catalpa ovata, attenuates induction of intestinal epithelial proinflammatory gene expression and reduces the severity of trinitrobenzene sulfonic acid-induced colitis in mice. Inflammatory Bowel Disease 10 564-572

Kim SW, Oleksyn DW, Rossi RM, Jordan CT, Sanz I, Chen L and Zhao J (2007) Protein kinase C-associated kinase PKK is required for NF-kB signaling and survival in diffuse large B-cell lymphoma cells. Blood in press

Kim SY (2006) Transglutaminase 2 in inflammation. Frontiers in Bioscience 11 3026-3035

Kim SY, Kim DH, Han SJ, Hyun JW and Kim HS (2007) Repression of matrix metalloproteinase gene expression by ginsenoside Rh2 in human astroglioma cells.Biochemical Pharmacology in press

Kim SY, Kim SH, Shin HY, Lim JP, Chae BS, Park JS, Hong SG, Kim MS, Jo DG, Park WH and Shin TY (2007) Effects of Prunella vulgaris on mast cell-mediated allergic reaction and inflammatory cytokine production. Experimental Biology and Medicine (Maywood) 232 921-926

Kim SY, Lee YC, Kim HK and Blaser MJ (2006) Helicobacter pylori CagA transfection of gastric epithelial cells induces interleukin-8. Cellular Microbiology 8 97-106

Kim SY, Lee EJ, Woo MS, Jung JS, Hyun JW, Min SW, Kim DH and Kim HS (2007) Inhibition of matrix metalloproteinase-9 gene expression by an isoflavone metabolite, irisolidone in U87MG human astroglioma cells. Biochemical Biophysical Research Communications in press

Kim T, Handa A, Iida J and Yoshida S (2007) RANKL expression in rat periodontal ligament subjected to a continuous orthodontic force. Archives of Oral Biology 52 244-250

Kim T, Yoon J, Cho H, Lee WB, Kim J, Song YH, Kim SN, Yoon JH, Kim-Ha J and Kim YJ (2005) Downregulation of lipopolysaccharide response in Drosophila by negative crosstalk between the AP1 and NF-kB signaling modules. Nature Immunolology 6 211-218

Kim TB, Kim SY, Moon KA, Park CS, Jang MK, Yun ES, Cho YS, Moon HB and Lee KY (2007) Five-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside attenuates poly (I:C)-induced airway inflammation in a murine model of asthma. Clinical and ExperimentalAllergy in press

Kim TH, Stone MA, Rahman P, Yoo DH, Park YW, Payne U, Hallett D and Inman RD (2005) Interleukin 1 and nuclear factor-kB polymorphisms in ankylosing spondylitis in Canada and Korea. Journal of Rheumatology 32 1907-1910

Kim TI, Jin SH, Kang EH, Shin SK, Choi KY and Kim WH (2002) The role of mitogen-activated protein kinases and their relationship with NF-kB and PPARgamma in indomethacin-induced apoptosis of colon cancer cells. Annals of the New York Academy of Sciences USA 973 241-245

Kim TK and Maniatis T (1997) The mechanism of transcriptional synergy of an in vitro assembled interferon-b enhanceosome. Molecular Cell 1 119-128

Kim WH, CHoi CH, Kang SK, Kwon CH and Kim YK (2005) Ceramide induces non-apoptotic cell death in human glioma cells. Neurochemistry Research 30 969-979

Kim WH, Hong F, Jaruga B, Hu Z, Fan S, Liang TJ and Gao B (2001) Additive activation of hepatic NF-kB by ethanol and HBX or HCV core protein: involvement of TNF-a receptor I-independent and -dependent mechanisms. FASEB Journal 15 2551-2553

Kim WJ, Back SH, Kim V, Ryu I and Jang SK (2005) Sequestration of TRAF2 into stress granules interrupts tumor necrosis factor signaling under stress conditions. Molecular and Cellular Biology 25 2450-2562

Kim WJ, Bae EM, Kang YJ, Bae HU, Hong SH, Lee JY, Park JE, Kwon BS, Suk K and Lee WH (2006) Glucocorticoid-induced tumour necrosis factor receptor family related protein (GITR) mediates inflammatory activation of macrophages that can destabilize atherosclerotic plaques. Immunology 119 421-429

Kim W-K and Baluda MA (1988) Proto-oncogene expression in chicken leukemic cells induced by avian myeloblastosis virus. Oncogene Research 3 147-154

Kim WK, Hwang SY, Oh ES, Piao HZ, Kim KW and Han IO (2004) TGF-beta1 represses activation and resultant death of microglia via inhibition of phosphatidylinositol 3-kinase activity. Journal of Immunology 172 7015-7023

Kim WK, Jang PG, Woo MS, Han IO, Piao HZ, Lee K, Lee H, Joh TH and Kim HS (2004) A new anti-inflammatory agent KL-1037 represses proinflammatory cytokine and inducible nitric oxide synthase (iNOS) gene expression in activated microglia. Neuropharmacology 47 243-252

Kim Y, Moon JS, Lee KS, Park SY, Cheong J, Kang HS, Lee HY and Kim HD (2004) Ca(2+)/calmodulin-dependent protein phosphatase calcineurin mediates the expression of iNOS through IKK and NF-kB activity in LPS-stimulated mouse peritoneal macrophages and RAW 264.7 cells. Biochemical and Biophysical Research Communications 314 695-703

Kim Y, Suh N, Sporn M and Reed JC (2002) An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis. Journal of Biological Chemistry 277 22320-22329

Kim YA, Lee WH, Choi TH, Rhee SH, Park KY and Choi YH (2003) Involvement of p21WAF1/CIP1, pRB, Bax and NF-kB in induction of growth arrest and apoptosis by resveratrol in human lung carcinoma A549 cells. International Journal of Oncology 23 1143-1149

Kim YA, LIm SY, Rhee SH, Park KY, Kim CH, Choi BT, Lee SJ, Park YM and Choi YH (2006) Resveratrol inhibits inducible nitric oxide synthase and cyclooxygenase-2 expression in beta-amyloid-treated C6 glioma cells. International Journal of Molecular Medicine 17 1069-1075

Kim YD, An SC, Oyama T, Kawamoto T and Kim H (2003) Oxidative stress, hogg1 expression and NF-kB activity in cells exposed to low level chromium. Journal of Occupational Health 45 271-277

Kim YG, Ohta T, Takahashi T, Kushiro A, Nomoto K, Yokokura T, Okada N and Danbara H (2006) Probiotic Lactobacillus casei activates innate immunity via NF-kB and p38 MAP kinase signaling pathways.
Microbes and Infection 8 994-1005

Kim YH, Choi KH, Park JW and Kwon TK (2005) LY294002 inhibits LPS-induced NO production through a inhibition of NF-kB activation: independent mechanism of phosphatidylinositol 3-kinase. Immunology Letters 99 45-50

Kim YH, Kim JM, Kim SN, Kim GS and Baek JH (2003) p44/42 MAPK activation is necessary for receptor activator of nuclear factor-kB ligand induction by high extracellular calcium. Biochemical and Biophysical Research Communications 304 729-735

Kim YH, Lee SH, Lee JY, Choi SW, Park JW and Kwon TK (2004) Triptolide inhibits murine-inducible nitric oxide synthase expression by down-regulating lipopolysaccharide-induced activity of nuclear factor-kB and c-Jun NH(2)-terminal kinase. European Journal of Pharmacology 494 1-9

Kim YH, Woo KJ, Lim JH, Kim S, Lee TJ, Jung EM, Lee JM, Park JW and Kwon TK (2005) 8-Hydroxyquinoline inhibits iNOS expression and nitric oxide production by down-regulating LPS-induced activity of NF-kB and C/EBPb in Raw 264.7 cells. Biochemical and Biophysical Research Communications 329 591-597

Kim YI, Park JE, Martinez-Hernandez A and Yi AK (2008) CpG DNA prevents liver injury and shock-mediated death by modulating expression of IL-1R-associated kinases. Journal of Biological Chemistry in press

Kim YJ, Hwang SY and Han IO (2006) Insoluble matrix components of glioma cells suppress LPS-mediated iNOS/NO induction in microglia.
Biochemical and Biophysical Research Communications 347 731-738

Kim YJ, Hwang SY, Hwang JS, Lee JW, Oh ES and Han IO (2007) C6 gioma cell insoluble matrix components enhance IFN-g-stimulated INOS/no production in BV2 microglial cells. Journal of Biological Chemistry in press

Kim YJ, Hwang SY, Oh ES, Oh S and Han IO (2006) IL-1beta, an immediate early protein secreted by activated microglia, induces iNOS/NO in C6 astrocytoma cells through p38 MAPK and NF-kB pathways. Journal of Neuroscience Research 84 1037-1046

Kim YJ, Rossa C and Kirckwood KL (2005) Prostaglandin production by human gingival fibroblasts inhibited by triclosan in the presence of cetylpyridinium chloride. Journal of Peridontology 76 1735-1742

Kim YJ, Yu JM, Joo HJ, Kim HK, Cho HH, Bae YC and Jung JS (2007) Role of CD9 in proliferation and proangiogenic action of human adipose-derived mesenchymal stem cells. Pflugers Archiv in press

Kim YK, Bourgeois CF, Pearson R, Tyagi M, West MJ, Wong J, Wu SY, Chiang CM and Karn J (2006) Recruitment of TFIIH to the HIV LTR is a rate-limiting step in the emergence of HIV from latency. EMBO Journal 25 3596-3604

Kim YK, Lee EK, Kang JK, Kim JA, You JS, Park JH, Seo DW, Hwang JW, Kim SN, Lee HY, Lee HW and Han JW (2006) Activation of NF-kB by HDAC inhibitor apicidin through Sp1-dependent de novo protein synthesis: its implication for resistance to apoptosis.Cell Death and Differentiation 13 2033-2041

Kim YK, Seo DW, Kang DW, Lee HY, Han JW and Kim SN (2006) Involvement of HDAC1 and the PI3K/PKC signaling pathways in NF-kB activation by the HDAC inhibitor apicidin.Biochemical and Biophysical Research Communications 347 1088-1093

Kim YM, Cao D, Reed W, Wu W, Jaspers I, Tal T, Bromberg PA and Samet JM (2007) Zn(2+)-induced NF-kB-dependent transcriptional activity involves site-specific p65/RelA phosphorylation. Cellular Signaling 19 538-546

Kim YM and Paik SG (2005) Induction of expression of inducible nitric oxide synthase by Taxol in murine macrophage cells. Biochemical and Biophysical Research Communications 326 410-416

Kim YM, Reed W, Lenz AG, Jaspers I, Silbajoris R, Nick HS and Samet JM (2005) Ultrafine carbon particles induce interleukin-8 gene transcription and p38 MAPK activation in normal human bronchial epithelial cells. American Journal of Physiology: Lung Cell and Molecular Physiology 288 L432-L441

Kim YS, Ahn Y, Hong MH, Joo SY, Kim KH, SOhn IS, Park HW, Hong YJ, Kim JH, Kim W, Jeong MH, Cho JG, Park JC and Kang JC (2007) Curcumin attenuates inflammatory responses of TNF-a-stimulated human endothelial cells. Journal of Cardiovascular Pharmacology 50 41-49

Kim YS, Ahn Y, Hong MH, Kim KH, Park HW, Hong YJ, Kim JH, Kim W, Jeong MH, Cho JG, Park JC and Kang JC (2007) Rosuvastatin suppresses the inflammatory responses through inhibition of c-Jun N-terminal kinase and nuclear factor-kB in endothelial cells.
Journal of Cardiovascular Pharmacology 49 376-383

Kim YS, Cho K-O, Lee HJ, Kim SY, Sato Y and Cho Y-J (2006) Down Syndrome ccandidate region 1 increases the stability of the IkBa protein: implications for its anti-inflammatory effects. Journal of Biological Chemistry 281 39051-39061

Kim YS, Han CY, Kim SW, Kim JH, Lee SK, Jung DJ, Park SY, Kang H, Choi HS, Lee JW and Pak YK (2001) The orphan nuclear receptor small heterodimer partner as a novel coregulator of nuclear factor-kappa b in oxidized low density lipoprotein-treated macrophage cell line RAW 264.7. Journal of Biological Chemistry 276 33736-33740

Kim YS, Han SJ, Ryu JH, Choi KH, Hong YS, Chung YH, Perrot S, Raibaud A, Brey PT and Lee WJ (2000) Lipopolysaccharide-activated kinase, an essential component for the induction of the antimicrobial peptide genes in Drosophila melanogaster cells. Journal of Biological Chemistry 275 2071-2079

Kim YS, Kim JS, Jung HC and Song IS (2004) The effects of thalidomide on the stimulation of NF-kB activity and TNF-a production by lipopolysaccharide in a human colonic epithelial cell line. Molecules and Cells 17 210-216

Kim YS, Kim SS, Cho JJ, Choi DH, Hwang O, Shin DH, Chun HS, Beal MF and Joh TH (2005) Matrix metalloproteinase-3: a novel signaling proteinase from apoptotic neuronal cells that activates microglia. Journal of Neuroscience 25 3701-3711

Kim YS and Milner JA (2005) Targets for indole-3-carbinol in cancer prevention. Journal of Nutritional Biochemistry 16 65-73

Kim YS, Nedospasov SA and Liu ZG (2005) TRAF2 plays a key, nonredundant role in LIGHT-lymphotoxin beta receptor signaling. Molecular and Cellular Biology 25 2130-2137

Kim YS, Schwabe RF, Qian T, Lemasters JJ and Brenner DA (2002) TRAIL-mediated apoptosis requires NF-kB inhibition and the mitochondrial permeability transition in human hepatoma cells. Hepatology 36 1498-1508

Kim YW, Zhao RJ, Park SJ, Lee JR, Cho IJ, Yang CH, Kim SG and Kim SC (2008) Anti-inflammatory effects of liquiritigenin as a consequence of the inhibition of NF-kB-dependent iNOS and proinflammatory cytokines production. British Journal of Pharmacology in press

Kim do Y, Jun JH, Lee HL, Woo KM, Ryoo HM, Kim GS, Baek JH and Han SB (2007) N-acetylcysteine prevents LPS-induced pro-inflammatory cytokines and MMP2 production in gingival fibroblasts. Archives of Pharmacal Research 30 1283-1292

Kimbrell MR, Warshakoon H, Cromer JR, Malladi S, Hood JD, Balakrishna R, Scholdberg TA and David SA (2008) Comparison of the immunostimulatory and proinflammatory activities of candidate Gram-positive endotoxins, lipoteichoic acid, peptidoglycan, and lipopeptides, in murine and human cells. Immunology Letters in press

Kimura A, Ohmichi M, Kawagoe J, Kyo S, Mabuchi S, Takahashi T, Ohshima C, Arimoto-Ishida E, Nishio Y, Inoue M, Kurachi H, Tasaka K and Murata Y (2004) Induction of hTERT expression and phosphorylation by estrogen via Akt cascade in human ovarian cancer cell lines. Oncogene 23 4505-4515

Kimura H, Inukai Y, Takii T, Furutani Y, Shibata Y, Hayashi H, Sakurada S, Okamoto T, Inoue J, Oomoto Y and Onozaki K (1998) Molecular analysis of constitutive IL-1alpha gene expression in human melanoma cells: autocrine stimulation through NF-kB activation by endogenous IL-1alpha. Cytokine 10 872-879

Kimura K and Gelmann EP (2002) Propapoptotic effects of NF-kB in LNCaP prostate cancer cells lead to serine protease activation. Cell Death & Differentiation 9 972-980

Kimura K, Bowen C, Spiegel S and Gelmann EP (1999) Tumor necrosis factor-alpha sensitizes prostate cancer cells to gamma-irradiation-induced apoptosis. Cancer Research 59 1606-1614

Kimura M, Haisa M, Uetsuka H, Takaoka M, Ohkawa T, Kawashima R, Yamatsuji T, Gunduz M, Kaneda Y, Tanaka N and Naomoto Y (2003) TNF combined with IFN-alpha accelerates NF-kB-mediated apoptosis through enhancement of Fas expression in colon cancer cells. Cell Death & Differentiation 10 718-728

Kimura K, Markowski M, Bowen C and Gelmann EP (2001) Androgen blocks apoptosis of hormone-dependent prostate cancer cells. Cancer Research 61 5611-5618

Kimura K, Nagaki M, Kaimi K, Saio M, Saeki T, Okuda Y, Kuwata K and Moriwaki H (2008) Critical role of CD44 in hepatotoxin-mediated liver injury. Journal of Hepatology in press

Kimura K, Nagaki M, Takai S, Satake S and Moriwaki H (2004) Pivotal role of nuclear factor kB signaling in anti-CD40-induced liver injury in mice. Hepatology 40 1180-1189

Kimura K, Teranishi S, Fukuda K, Kawamoto K and Nishida T (2008) Delayed disruption of barrier function in cultured human corneal epithelial cells induced by tumor necrosis factor-a in a manner dependent on NF-kB. INvestigative Ophthalmology and Visual Science 49 565-571

Kimura MY, Hosokawa H, Yamashita M, Hasegawa A, Iwamura C, Watarai H, Taniguchi M, Takagi T, Ishii S and Nakayama T (2005) Regulation of T helper type 2 cell differentiation by murine Schnurri-2. Journal of Experimental Medicine 201 397-408

Kimura MY, Iwamura C, Suzuki A, Miki T, Hasegawa A, Sugaya K, Yamashita M, Ishii S and Nakayama T (2007) Schnurri-2 controls memory Th1 and th2 cell numbers in vivo.Journal of Immunology 178 4926-4936

Kimura N, Miyakawa Y, Kohmura K, Umezawa K, Ikeda Y and Kizaki M (2007) Targeting NF-kB and induction of apoptosis by novel NF-kappaB inhibitor dehydroxymethylepoxyquinomicin (DHMEQ) in Burkitt lymphoma cells. Leukemia Research in press

Kimura T, Nakamura H,Koyama S, Ogita K, Tabata C, Tsutsui T, Shimoya K, Koyama M, Kaenda Y and Murata Y (2005) In vivo gene transfer into the mouse uterus: A powerful tool for investigating implantation physiology. Journal of Reporductive Immunology 67 13-20

Kimura T, Nakamura H, Ogita K, Koyama S, Tomiie M, Yoshida S, Tsutsui T, Shimoya K, Koyama M and Murata Y (2004) Effect of proteasome pathway on initiation of mouse labor induced by antiprogesterone. American Journal of Reproductive Immunology 52 317-322

Kimura T, Sakaida I, Terai S, Matsumura Y, Uchida K and Okita K (1997) Inhibition of tumor necrosis factor-a production retards liver regeneration after partial hepatectomy in rats. Biochemical and Biophysical Research Communications 231 557-560

Kimura YN, Watari K, Fotovati A, Hosoi F, Yasumoto K, Izumi H, Kohno K, Umezawa K, Iguchi H, Shirouzu K, Takamori S, Kuwano M and Ono M (2007) Inflammatory stimuli from macrophages and cancer cells synergistically promote tumor growth and angiogenesis. Cancer Science 98 2009-2018

Kin H, Wang NP, Mykytenko J, Reeves J, Deneve J, Jiang R, Zatta AJ, Guyton RA, Vinten-Johansen J and Zhao ZQ (2008) Inhibition of myocardial apoptosis by postconditioning is associated with attenuation of oxidative stress-mediated nuclear factor-kB translocation and TNFa release. Shock 29 761-768

Kin NW and Sanders VM (2006) CD86 stimulation on a B cell activates the phosphatidylinositol 3-kinase/Akt and phospholipase Cgamma2/protein kinase Calphabeta signaling pathways. Journal of Immunology 176 6727-6735

King AE, Critchley HO and Kelly RW (2001) The NF-kB pathway in human endometrium and first trimester decidua. Molecular Human Reproduction 7 175-183

King DJ, Bassett SE, Li X, Fennewald SA, Herzog NK, Luxon BA Shope R and Gorenstein DG (2002) Combinatorial selection and binding of phosphorothioate aptamers targeting human NF-kB RelA(p65) and p50. Biochemistry 41 9696-9706

King KE, Ponnamperuma RM, Allen C, Lu H, Duggal P, Chen Z, Van Waes C and Weinberg WC (2008) The p53 homologue DeltaNp63alpha interacts with the nuclear factor-kB pathway to modulate epithelial cell growth. Cancer Resarch 68 5122-5131

King NJ and Kesson AM (2003) Interaction of flaviviruses with cells of the vertebrate host and decoy of the immune response. Immunol Cell Biol 81 207-216

King NJ, Shrestha B and Kesson AM (2003) Immune modulation by flaviviruses. Advances in Virus Research 60 121-155

King TA, Ghazaleh RA, Juhn SK, Adams GL and Ondrey FG (2005) Induction of heat shock protein 70 inhibits NF-kB in squamous cell carcinoma. Otolaryngol Head Neck Surgery133 70-79

Kingman S (1995) Do variants of cytokine genes help explain autoimmunity? Journal of NIH Research 7 35-36

Kiningham KK, Cardozo ZA, Cook C, Cole MP, Stewart JC, Tassone M, Coleman MC and Spitz DR (2008) All-trans-retinoic acid induces manganese superoxide dismutase in human neuroblastoma through NF-kB. Free Radical Biology and Medicine in press

Kiningham KK, Daosukho C and St Clair DK (2004) IkB-a identified as labile repressor of manganese superoxide dismutase (MnSOD) expression. Biochemical Journal 384 543-549

Kiningham KK, Xu Y, Daosukho C, Popova B and St Clair DK (2001) Nuclear factor kB-dependent mechanisms coordinate the synergistic effect of PMA and cytokines on the induction of superoxide dismutase 2. Biochemical Journal 353 147-156

Kinoshita T, Kondoh C, Hasegawa M, Imamura R and Suda T (2006) Fas-associated factor 1 is a negative regulator of PYRIN-containing Apaf-1-like protein 1. InternationalImmunology in press

Kinjyo I, Hanada T, Inagaki-Ohara K, Mori H, Aki D, Ohishi M, Yoshida H, Kubo M and Yoshimura A (2002)
SOCS1/JAB is a negative regulator of LPS-induced macrophage activation. Immunity 17 583-591

Kino T and Chrousos GP (2003) Tumor necrosis factor alpha receptor-and Fas-associated FLASH inhibits transcriptional activity of the glucocorticoid receptor by binding to and interfering with its interaction with p160 type nuclear receptor coactivators. Journal of Biological Chemistry 278 3023-3029

Kino T, Slobodskaya O, Pavlakis GN and Chrousos GP (2002) Nuclear receptor coactivator p160 proteins enhance the HIV-1 long terminal repeat promoter by bridging promoter-bound factors and the Tat-P-TEFb complex. Journal of Biological Chemistry 277 2396-2405

Kinoshita K, Sato K, Hori M, Ozaki H and Karaki H (2003) Decrease in the activity of the L-type Ca2+ -channels and its reversal by NF-kB inhibitors in colonic smooth muscle isolated from a TNBS-induced colitis model rat. American Journal of Physiology: Gastrointestinal and Liver Physiology 285 G483-G493

Kinoshita D, Hirota F, Kaisho T, Kasai M, Izumi K, Bando Y, Mouri Y, Matsushima A, Niki S, Han H, Oshikawa K, Kuroda N, Maegawa M, Irahara M, Takeda K, Akira S and Matsumoto M (2006) Essential role of IkB Kinase alpha in thymic organogenesis required for the establishment of self-tolerance. Journal of Immunology 176 3995-4002

Kinoshita T, Wang Y, Hasegawa M, Imamura R and Suda T (2005) PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion. Journal of Biological Chemistry 280 21720-21725

Kirch HC, Flaswinkel S, Rumpf H, Brockmann D and Esche H (1999) Expression of human p53 requires synergistic activation of transcription from the p53 promoter by AP-1, NF-kB and Myc/Max. Oncogene 18 2728-2738

Kirchhoff S, Wilhelm D, Angel P and Hauser H (1999) NFkB activation is required for interferon regulatory factor-1-mediated interferon beta induction. European Journal of Biochemistry 261 546-554

Kirchner D, Duyster J, Ottmann O, Schmid RM, Bergmann L and Munzert G (2003) Mechanisms of Bcr-Abl-mediated NF-kB/Rel activation. Experimental Hematology 31 504-511

Kirchner EA, Mols G, Hermle G, Muehlschlegel JD, Geiger KK, Guttmann J and Pahl HL (2005) Reduced activation of immunomodulatory transcription factors during positive end-expiratory pressure adjustment based on volume-dependent compliance in isolated perfused rabbit lungs. British Journal of Anaesthesiology 94 530-535

Kiriakidis S, Andreakos E, Monaco C, Foxwell B, Feldmann M and Paleolog E (2003) VEGF expression in human macrophages is NF-kB-dependent: studies using adenoviruses expressing the endogenous NF-kB inhibitor IkBa and a kinase-defective form of the IkB kinase 2. Journal of Cell Science 116 665-674

Kirillova I, Chaisson M and Fausto N (1999) Tumor necrosis factor induces DNA replication in hepatic cells through nuclear factor kB activation. Cell Growth & Differentiation 10 819-828

Kirito K, Watanabe T, Sawada K, Endo H, Ozawa K and Komatsu N (2001) Thrombopoietin regulates Bcl-xL gene expression through Stat5 and phosphatidylinositol 3-kinase activation pathways. Journal of Biological Chemistry 277 8329-8337

Kiritoshi S, Nishikawa T, Sonoda K, Kukidome D, Senokuchi T, Matsuo T, Matsumura T, Tokunaga H, Brownlee M and Araki E (2003) Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: potential role in diabetic nephropathy. Diabetes 52 2570-2577

Kirov N, Childs S, O’Connor M and Rushlow C (1994) The Drosophila dorsal morphogen represses the tolloid gene by interacting with a silencer element. Molecular and Cellular Biology 14 713-722

Kirov N, Zhelnin, Shah J and Rushlow C (1993) Conversion of a silencer into an enhancer: evidence for a co-repressor in dorsal-mediated repression in Drosophila. EMBO Journal 12 3193-3199

Kirsch BM, Zeyda M, Stuhlmeier K, Grisar J, Smolen JS, Watschinger B, Stulnig TM, Horl WH, Zlabinger GJ and Saemann MD (2005) The active metabolite of leflunomide, A77 1726, interferes with dendritic cell function. Arthritis Research Therapy 7 R694-R703

Kirstein L, Cvekl A, Chauhan BK and Tamm ER (2000) Regulation of human myocilin/TIGR gene transcription in trabecular meshwork cells and astrocytes: role of upstream stimulatory factor. Genes Cells 5 661-676

Kis A, Yellon DM and Baxter GF (2003) Role of nuclear factor-kB activation in acute ischaemia-reperfusion injury in myocardium. British Journal of Pharmacology 138 894-900

Kis K, Bodai L, Polyanka H, Eder K, Pivarcsi A, Duda E, Soos G, Bata-Csorgo Z and Kemeny L (2006) Budesonide, but not tacrolimus, affects the immune functions of normal human keratinocytes.
International Immunopharmacology 6 358-368

Kishida A, Matsuyama T, Kitajima I, Maruyama I and Akashi M (2001) Study of cell-material interaction by estimating NF-kB activation in HeLa S3 cells adhered onto hydrophilic substrates. Biomaterials 22 541-546

Kishida O, Miyazaki Y, Murayama Y, Ogasa M, Miyazaki T, Yamamoto T, Watabe K, Tsutsui S, Kiyohara T, Shimomura I and Shinomura Y (2004) Gefitinib (“Iressa”, ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells. Cancer Chemotherapy and Pharmacology 55 393-403

Kishida S, Sanjo H, Akira S, Matsumoto K and Ninomiya-Tsuji J (2005) TAK1-binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL-1 signaling pathway. Genes Cells 10 447-454

Kishida Y, Yoshikawa H and Myoui A (2007) Parthenolide, a natural inhibitor of nuclear factor-kB, inhibits lung colonization of murine osteosarcoma cells. ClinicalCancer Research 13 59-67

Kishikawa H, Miura S, Yoshida H, Hirokawa M, Nakamizo H, Higuchi H, Adachi M, Nakatsumi RC, Suzuki H, Saito H and Ishii H (2002) Transmural pressure induces IL-6 secretion by intestinal epithelial cells. Clinical and Experimental Immunology 129 86-91

Kishimoto A, Fujita T, Shiba H, Komatsuzawa H, Takeda K, Kaiya M, Hayashida K, Kawaguchi H and Kurihara H (2008) Irsogladine maleate abolishes the increase in interleukin-8 levels caused by outer membrane protein 29 from Aggregatibacter (Actinobacillus) actinomycetemcomitans through the ERK pathway in human gingival epithelial cells. Journal of Periodontal Research in press

Kishimoto K, Matsumoto K and Ninomiya-Tsuji J (2000) TAK1 mitogen-activated protein kinase is activated by autophosphorylation within its activation loop. Journal of Biological Chemistry 275 7359-7364

Kishimoto M, Yoshimura A, Naito M, Okamoto K, Yamamoto K, Golenbock DT, Hara Y and Nakayam K (2006) Gingipains inactivate a cell surface ligand on Porphyromonas gingivalis that induces TLR2-and TLR4-independent signaling. Microbiology andImmunology 50 315-325

Kishore N, Sommers C, Mathialagan S, Guzova J, Yao M, Hauser S, Huynh K, Bonar S, Mielke C, Albee L, Weier R, Graneto M, Hanau C, Perry T and Tripp CS (2003) A selective IKK-2 inhibitor blocks NF-kB-dependent gene expression in IL-1beta stimulated synovial fibroblasts. Journal of Biological Chemistry 278 32861-32871

Kishore R, Hill JR, McMullen MR, Frenkel J and Nagy LE (2002) ERK1/2 and Egr-1 contribute to increased TNF-alpha production in rat Kupffer cells after chronic ethanol feeding. American Journal of Physiology: Gastrointestinal Liver Physiology 282 G6-G15

Kislinger T, Fu C, Huber B, Qu W, Taguchi A, Du Yan S, Hofmann M, Yan SF, Pischetsrieder M, Stern D and Schmidt AM (1999) N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression. Journal of Biological Chemistry 274 31740-31749

Kislinger T, Tanji N, Wendt T, Qu W, Lu Y, Ferran LJ, Jr., Taguchi A, Olson K, Bucciarelli L, Goova M, Hofmann MA, Cataldegirmen G, D’Agati V, Pischetsrieder M, Stern DM and Schmidt AM (2001) Receptor for advanced glycation end products mediates inflammation and enhanced expression of tissue factor in vasculature of diabetic apolipoprotein E-null mice. Arterioscler Thromb Vasc Biol 21 905-910

Kispert A and Herrmann BG (1993) The Brachyury gene encodes a novel DNA binding protein. EMBO Journal 12 3211-3220

Kiss DL, Xu W, Gopalan S, Buzanowska K, Wilczynska KM, Rydel RE and Kordula T (2005) Duration of alpha-antichymotrypsin gene activation by interleukin-1 is determined by efficiency of inhibitor of nuclear factor kBa resynthesis in primary human astrocytes. Journal of Neurochemistry 92 730-738

Kiss K, Kiss J, Rudolf E, Cervinka M nad Szeberenyi J (2004) Sodium salicylate inhibits NF-kB and induces apoptosis in PC12 cells. Journal of Biochemical and Biophysical Methods 61 229-240

Kisseleva T, Song L, Vorontchikhina M, Feirt N, Kitajewski J and Schindler C (2006) NF-kB regulation of endothelial cell function during LPS-induced toxemia and cancer.Journal of Clinical Investigation in press

Kistler B, Rolink A, Marienfeld R, Neumann M and Wirth T (1998) Induction of nuclear factor-kB during primary B cell differentiation. Journal of Immunology 160 2308-2317

Kitada S, Pedersen IM, Schimmer AD and Reed JC (2002) Dysregulation of apoptosis genes in hematopoietic malignancies. Oncogene 21 3459-3474

Kitagawa K, Hamada Y, Kato Y, Nakai K, Nishizawa M, Ito S and Okumura T (2004) Epidermal growth factor and interleukin-1{beta} stimulate synergistically the production of nitric oxide in rat intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol in press

Kitajima I (2007) Development of molecular pathology analysis testing which can be practiced in the hospital laboratory. The clinical application of a transcription factor activation test [Article in Japanese]. Rinsho Byori 55 262-271

Kitajima I, Shinohara T, Bilakovics J, Brown DA, Xu X and Nereneberg M (1992) Ablation of transplanted HTLV-I Tax-transformed tumors in mice by antisense inhibition of NF-kB. Science 258 1792-1795

Kitajima I, Unoki K and Maruyama I (1999) Phosphorothioate oligodeoxynucleotides inhibit basic fibroblast growth factor-induced angiogenesis in vitro and in vivo. Antisense Nucleic Acid Drug Development 9 233-239

Kitamoto S, Egashira K, Kataoka C, Koyanagi M, Katoh M, Shimokawa H, Morishita R, Kaneda Y, Sueishi K and Takeshita A (2000) Increased activity of nuclear factor-kB participates in cardiovascular remodeling induced by chronic inhibition of nitric oxide synthesis in rats. Circulation 102 806-812

Kitamura C, Nishihara T, Ueno Y, Chen KK, Morotomi T, Yano J, Nagayoshi M and Terashita M (2006) Effects of sequential exposure to lipopolysaccharide and heat stress on dental pulp cells.
Journal of Cellular Biochemistry in press

Kitamura H, Kanehira K, Shiina T, Morimatsu M, Jung BD, Akashi S and Saito M (2002) Bacterial lipopolysaccharide induces mRNA expression of an IkB MAIL through toll-like receptor 4. Journal of Veterinary Medical Science 64 419-422

Kitamura H, Matsushita Y, Iwanaga T, Mori K, Kanehira K, Fujikura D, Morimatsu M and Saito M (2003) Bacterial lipopolysaccharide-induced expression of the IkappaB protein MAIL in B-lymphocytes and macrophages. Archives of Histology and Cytology 66 53-62

Kitamura M (1999) NF-kB-mediated self defense of macrophages faced with bacteria. European Journal of  Immunology 29 1647-1655

Kitamura M (2000) Adoptive transfer of nuclear factor-kB-inactive macrophages to the glomerulus. Kidney International 57 709-716

Kitamura T, Sekimata M, Kikuchi S and Homma Y (2005) Involvement of poly(ADP-ribose) polymerase 1 in erbB2 expression in rheumatoid synovial cells. American Journal Physiology: Cell Physiology 289 C82-C88

Kitano A, Saika S, Yamanaka O, Ikeda K, Okada Y, Shirai K and Reinach PS (2007) Emodin suppression of ocular surface inflammatory reaction. InvestigativeOphthalmology & Visual Science 48 5013-5022

Kitaoka Y, Kitaoka Y, Kwong JM, Ross-Cisneros FN, Wang J, Tsai RK, Sadum AA and Lam TT (2006) TNF-alpha-induced optic nerve degeneration and nuclear factor-kB p65.Investigative Ophthalmology and Vision Science 47 1448-1457

Kitaoka Y, Kumai T, Kitaoka Y, Lam TT, Munemasa Y, Isenoumi K, Motoki M, Kuribayashi K, Kogo J, Kobayashi S and Ueno S (2004) Nuclear factor-kB p65 in NMDA-induced retinal neurotoxicity. Brain Research Molecular Brain Research 131 8-16

Kitaoka Y, Munemasa Y, Nakazawa T and Ueno S (2007) NMDA-induced interleukin-1beta expression is mediated by nuclear factor-kB p65 in the retina. Brain Research in press

Kitatani K, Akiba S and Sato T (2004) Ceramide-induced enhancement of secretory phospholipase A(2) expression via generation of reactive oxygen species in tumor necrosis factor-alpha-stimulated mesangial cells. Cell Signaling 16 967-974

Kitaura H, Sands MS, Aya K, Zhou P, Hirayama T, Uthgenannt B, Wei S, Takeshita S, Novack DV, Silva MJ, Abu-Amer Y, Ross FP and Teitelbaum SL (2004) Marrow stromal cells and osteoclast precursors differentially contribute to TNF-a-induced osteoclastogenesis in vivo. Journal of Immunology 173 4838-4846

Kitaura H, Zhou P, Kim HJ, Novack DV, Ross FP and Teitelbaum SL (2005) M-CSF mediates TNF-induced inflammatory osteolysis. Journal of Clinical Investigation 115 3418-3427

Kitamei H, Iwabuchi K, Namba K, Yoshida K, Yanagawa Y, Kitaichi N, Kitamura M, Ohno S and Onoe K (2006) Amelioration of experimental autoimmune uveoretinitis (EAU) with an inhibitor of nuclear factor-kB (NF-kB), pyrrolidine dithiocarbamate. Journal ofLeukoctye Biology 79 1193-1201

Kitazawa M, Nakano T, Chuujou H, Shiojiri E, Iwasaki K and Sakamoto K (2002) Intracellular redox regulation by a cystine derivative suppresses UV-induced NF-kB activation. FEBS Letters 526 106

Kitazawa M, Shibata Y, Hashimoto S, Ohizumi Y and Yamakuni T (2006) Proinsulin C-peptide stimulates a PKC/IkB/NF-kB signaling pathway to activate COX-2 gene transcription in Swiss 3T3 fibroblasts.
Journal of Biochemistry (Tokyo) 139 1083-1088

Kitawawa R and Kitazawa S (2006) Methylation status of a single CpG locus 3 bases upstream of TATA-box of RANKL gene promoter modulates cell- and tissue-specific RANKL expression and osteoclastogenesis. Molecular Endocrinology in press

Kitazawa S and Kitazawa R (2002) Epigenetic control of mouse receptor activator of NF-kB ligand gene expression. Biochemical and Biophysical Research Communications 293 126-131

Kitson J, Raven T, Jiang Y-P, Goeddel DV, Giles KM, Pun K-T, Grinham CJ, Brown R and Farrow SN (1996) A death-domain-containing receptor that mediates apoptosis. Nature 384 372-375

Kittaka A, Kuze T, Asakura T, Ito K, Miyasaka T and Inoue J (1998) Oligonucleotides bearing 5-formyl-2′-O-methyluridine: preference in binding affinity to the NF-kB (p50)2 homo- and p50/p65 heterodimers. Bioorganic Medicinal Chemistry Letters 8 3207-3210

Kittaka N, Takemasa I, Takeda Y, Marubashi S, Nagano H, Umeshita K, Dono K, Matsubara K, Matsuura N and Monden M (2008) Molecular mapping of human hepatocellular carcinoma provides deeper biological insight from genomic data. European Journal of Cancer in press

Kittan G, Kumar KB, Guruvayoorappan C and Kuttan R (2007) Antitumor, anti-invasion, and antimetastaic effects of curcumin. Advances in Experimental Medicine and Biology 595 173-184

Kizaki T, Izawa T, Sakurai T, Haga S, Taniguchi N, Tajiri H, Watanabe K, Day NK, Toba K and Ohno H (2008) beta(2)-Adrenergic receptor regulates Toll-like receptor-4-induced nuclear factor-kB activation through beta-arrestin 2. Immunology in press

Klaas CA, Wagner G, Laufer S, Sosa S, Della Loggia R, Bomme U, Pahl HL and Merfort I (2002) Studies on the anti-inflammatory activity of phytopharmaceuticals prepared from Arnica flowers. Planta Med 68 385-391

Klaffenbach D, Rascher W, Rollinghoff M, Dotsch J, Meissner U and Schnare M (2005) Regulation and signal transduction of Toll-like receptors in human chorioncarcinoma cell lines. Am J Reprod Immunol 53 77-84

Klahr S (1999) Mechanisms of progression of chronic renal damage. Journal of Nephrology 12 Suppl 2 S53-62

Klahr S and Morrissey JJ (1998) The role of growth factors, cytokines, and vasoactive compounds in obstructive nephropathy. Seminars in Nephrology 18 622-632

Klahr S and Morrissey J (2003) Progression of chronic renal disease. American Journal of Kidney Disease 41 S3-S7

Klaitman V and Almog Y (2003) Corticosteroids in sepsis: a new concept for an old drug. Israel Medical Association Journal 5 51-55

Klamon LD and Thorley-Lawson DA (1995) Characterization of the CD48 gene demonstrates a positive element that is specific to Epstein-Barr virus-immortalized B-cell lines and contains an essential NF-kB element. Journal of Virology 69 871-881

Klatt A, Zhang Z, Kalantari P, Hankey PA, Gilmour DS and Henerson AJ (2008) The receptor tyrosine kinase RON represses HIV-1 transcription by targeting RNA polymerase II processivity. Journal of Immunology 180 1670-1677

Klaunig JE and Kamendulis LM (2004) The role of oxidative stress in carcinogenesis. Annual Revew of Pharmacology and Toxicology 44 239-267

Klebanoff SJ, Watts DH, Mehlin C and Headley CM (1999) Lactobacilli and vaginal host defense: activation of the human immunodeficiency virus type 1 long terminal repeat, cytokine production, and NF-kB. Journal of Infectious Disease 179 653-660

Klebl FH, Bregenzer N, Rogler G, Straub RH, Scholmerich J and Andus T (2003) Treatment of pouchitis with dehydroepiandrosterone (DHEA) – a case report. Z Gastroenterol 41 1087-1090

Kleemann R, Gervois PP, Verschuren L, Staels B, Princen HM and Kooistra T (2003) Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFkB ~C/EBP-beta complex formation. Blood 101 545-551

Kleemann R, Verschuren L, De Rooij BJ, Lindeman J, De Maat MM, Szalai AJ, Princen HM and Kooistra T (2004) Evidence for anti-inflammatory activity of statins and PPAR{alpha}-activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes in vitro. Blood 103 4188-4194

Kleemann R, Vershuren L, van Erk MJ, Nikolsky Y, Cnubben NH, Verheij ER, Smilde AK, Hendriks HF, Zadelaar S, SMith GJ, Kaznacheev V, Nikolskaya T, Melnikov A, Hurt-Camejo E, van der Greef J, van Ommen B and Kooistra T (2007) Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis. Genome Biology 8 R200

Klefstrom J, Arighi E, Littlewood T, Jaattela M, Saksela E, Evan GI and Alitalo K (1997) Induction of TNF-sensitive cellular phenotype by c-Myc involves p53 and impaired NF-kB activation. EMBO Journal 16 7382-7392

Klei LR and Barchowsky A (2008) Positive signaling interactions between arsenic and ethanol for angiogenic gene induction in human microvascular endothelial cells. Toxicological Sciences in press

Klein BS, Liptay S, Schmid RM and Hameister H (1999) Assignment of Nfkbib to murine chromosome bands 7A3-B3 by in situ hybridization. Cytogenet Cell Genet 85 308-309

Klein C, Wustefeld T, Heinrich PC, Streetz KL, Manns MP and Trautwein C (2003) ME3738 protects from concanavalin A-induced liver failure via an IL-6-dependent mechanism. European Journal of Immunology 33 2251-2261

Klein D, Barbe-Tuana F, Pugliese A, Ichii H, Garza D, Gonzalez M, Molano RD, Ricordi C and Pastori RL (2005) A functional CD40 receptor is expressed in pancreatic beta cells. Diabetologia 48 268-276

Klein D, Timoneri F, Ichii H, Ricordi C and Pastori RL (2008) CD40 activation in human pancreatic islets and ductal cells. Diabetologia in press

Klein EA, Yang C, Kazanietz MG and Assoian RK (2007) NFkB-independent signaling to the cyclin D1 gene by Rac. Cell Cycle in press

Klein S, De Fougerolles AR, Blaikie P, Khan L, Pepe A, Green CD, Koteliansky V and Giancotti FG  (2002) alpha5beta1 Integrin activates an NF-kB-dependent program of gene expression important for angiogenesis and inflammation. Molecular and Cellular Biology 22 5912-5922

Klein SL, Cernetich A, Hilmer S, Hoffman EP, Scott AL and Glass GE (2004) Differential expression of immunoregulatory genes in male and female Norway rats following infection with Seoul virus. Journal of Medical Virology 74 180-190

Kleinert H, Pautz A, Linker K and Schwarz PM (2004) Regulation of the expression of inducible nitric oxide synthase. European Journal of Pharmacology 500 255-266

Kleinert H, Schwarz PM and Forstermann U (2003) Regulation of the expression of inducible nitric oxide synthase. Biol Chem 384 1343-1364

Kleinert H, Wallerath T, Fritz G, Ihrig-Biedert I, Rodriguez-Pascual F, Geller DA and Forstermann U (1998) Cytokine induction of NO synthase II in human DLD-1 cells: roles of the JAK-STAT, AP-1 and NF-kB-signaling pathways. British Journal of Pharmacology 125 193-201

Kleinman MT, Araujo JA, Nel A, Sioutas C, Campbell A< Cong PQ, Li H and Bondy SC (2008) Inhaled ultrafine particulate matter affects CNS inflammatory processes and may act via MAP kinase signaling pathways. Toxicology Letters in press

Kleino A, Myllymaki H, Kallio J, Vanha-Aho LM, Oksanen K, Ulvila J, Hultmark D, Valanne S and Ramet M (2008) Pirk is a negative regulator of the Drosophila imd pathway. Journal of Immunology 180 5413-5422

Klement JF, Rice NR, Car BD, Abbondanzo SJ, Powers GD, Bhatt H, Chen C-H, Rosen CA and Stewart CL (1996) IkBa deficiency results in a sustained NF-kB response and severe widespread dermatitis in mice. Molecular and Cellular Biology 16 2341-2349

Klemm S, Gutermuth J, Hultner L, Sparwasser T, Behrendt H, Peschel C, Mak TW, Jakob T and Ruland J (2006) The Bcl10-Malt1 complex segregates Fc{varepsilon}RI-mediated nuclear factor kB activation and cytokine production from mast cell degranulation.
Journal of Experimental Medicine 203 337-347

Klemm S and Ruland J (2006) Inflammatory signal transduction from the FcepsilonRI to NF-kB. Immunobiology 211 815-820

Klemm S, Zimmermann S, Peschel C, Mak TW and Ruland J (2006) Bcl10 and Malt1 control lysophosphatidic acid-induced NF-kB activation and cytokine production. Proceedings of the National Academy of Sciences USA in press

Kletsas D, Pratsinis H, Mariatos G, Zacharatos P and Gorgoulis VG (2004) The proinflammatory phenotype of senescent cells: the p53-mediated ICAM-1 expression. Annals of the New York Academy of Sciences 1019 330-332

Kline M, Donovan K, Wellik L, Lust C, Jin W, Moon-Tasson L, Xiong Y, WItzig TE, Kumar S, Rajkumar SV and Lust JA (2006) Cytokine and chemokine profiles in multiple myeloma; significance of stromal interaction and correlation of IL-8 production with disease progression. Leukemia Research in press

Klingenberg R, Autschbach F, Gleissner C, Giese T, Wambsganss N, Sommer N, Richter G, Katus HA and Dengler TJ (2005) Endothelial inducible costimulator ligand expression is increased during human cardiac allograft rejection and regulates endothelial cell-dependent allo-activation of CD8(+) T cells in vitro. European Journal of Immunology 35 1712-1721

Klingmuller Y, Bauer A, Bohl S, Nickel PJ, Breitkopf K, Dooley S, Zellmer S, Kern C, Merfort I, Sparna T, Donauer J, Walz G, Geyer M, Kreutz C, Hermes M, Gotschel F, Hecht A, Walter D, Egger L, Neubert K, Borner C, Brulport M, Schormann W, Sauer C, Baumann F, Preiss R, McaNelly S, Godoy P, Wiercinska E, Ciuclan L, Edelmann J, Zeilinger K, Heinrich M, Zanger UM, Gebhardt R, Maiwald T, Heinrich R, Timmer J, von Weizsacker F and Hengstler JG (2006) Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways. Systems Biology (Stevenage) 153 433-447

Klinke 2nd DJ, Ustyugova IV, Brundage KM and Barnett JB (2008) Modulating temporal control of NF-kB activation: implications for therapeutic and assay selection.  Biophysical Journal in press

Klinkenberg M, Van Huffel S, Heyninck K and Beyaert R (2001) Functional redundancy of the zinc fingers of A20 for inhibition of NF- kappaB activation and protein-protein interactions. FEBS Letters 498 93-97

Klooster AR and Bernier SM (2005) Tumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene expression by chondrocyte. Arthritis Research and Therapy 7 R127-138

Klotz L, Schmidt M, Giese T, Sastre M, Knolle P, Klockgether T and Heneka MT (2005) Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients. Journal of Immunology 175 4948-4955

Klug CA, Gerety SJ, Shah PC, Chen Y-Y, Rice NR, Rosenberg N and Singh H (1994) The v-abl tyrosine kinase negatively regulates NF-kB/Rel factors and blocks k gene transcription in pre-B lymphocytes. Genes & Development 8 678-687

Kluiver J, Kok K, Pfeil I, de Jong D, Blokzijl T, Harms G, van der Vlies P, Diepstra A, Atayar C, Poppema S, Kuppers R and van den Berg A (2007) Global correlation of genome and transcriptome changes in classical Hodgkin lymphoma. Hematology andOncology 25 21-29

Kluiver J, van den Berg A, de Jong D, Blokzijl T, Harms G, Bouwman E, Jacobs S, Poppema S and Kroesen BJ (2007) Regulation of pri-microRNA BIC transcription and processing in Burkitt lymphoma. Oncogene 26 3769-3776

Klysik J, Theroux SJ, Sedivy JM, Joffit JS and Bokelheide K (2007) Signaling crossroads: The function of Raf kinase inhibitory protein in cancer, the central nervous system and reproduction. Cellular Signaling in press

Knonickova E, Melkusova P, Harmatha J, Vokac K, Farghali H and Zidek Z (2008) Inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPase thapsigargin stimulates production of nitric oxide and secretion of interferon-gamma. European Journal of Pharmacology in press

Knecht H, Berger C, Rothenberger S, Odermatt BF and Brousset P (2001) The role of Epstein-Barr virus in neoplastic transformation. Oncology 60 289-302

Knecht H, McQuain C, Berger C, Rothenberger S, Martin J, Esslinger C, Drexler HG, Cai YC and Quesenberry PJ (1999) Latent membrane protein 1 associated signaling pathways are important in tumor cells of Epstein-Barr virus negative Hodgkin’s disease. Oncogene 18 7161-7167

Knecht H, McQuain C, Martin J, Rothenberger S, Drexler HG, Berger C, Bachmann E, Kittler ELW, Odermatt BF and Quesenberry PJ (1996) Expression of the LMP1 oncoprotein in the EBV negative Hodgkin’s disease cell line L-428 is associated with Reed-Sternberg cell morphology. Oncogene 13 947-953

Knipp BS, Ailawadi G, Ford JW, Peterson DA, Eagleton MJ, Roelofs KJ, Hannawa KK, Deogracias MP, Ji B, Logsdon C, Graziano KD, Simeone DM, Thompson RW, Henke PK, Stanley JC and Upchurch GR (2004) Increased MMP-9 expression and activity by aortic smooth muscle cells after nitric oxide synthase inhibition is associated with increased nuclear factor-kB and activator protein-1 activity(1). Journal of Surgical Research 116 70-80

Kniss DA, Rovin B, Fertel RH and Zimmerman PD (2001) Blockade NF-kB activation prohibits TNF-alpha-induced cyclooxygenase-2 gene expression in ED27 trophoblast-like cells. Placenta 22 80-89

Knittweis J (1998) An ataxia telangiectasia model: inefficient cell differentiation and possible reversal by serine protease inhibitors, tumor necrosis factor inhibitors, dexamethasone, and glutathione enhancers. Medical Hypotheses 51 53-57

Knobloch TJ, Madhavan S, Nam J, Agarwal Jr S and Agarwal S (2008) Regulation of chondrocytic gene expression by biomechanical signals. Critical Reviews of Eukaryotic Gene Expression 18 139-150

Knop J and Martin MU (1999) Effects of IL-1 receptor-associated kinase (IRAK) expression on IL-1 signaling are independent of its kinase activity. FEBS Letters 448 81-85

Knop J, Wesche H, Lang D and Martin MU (1998) Effects of overexpression of IL-1 receptor-associated kinase on NFkB activation, IL-2 production and stress-activated protein kinases in the murine T cell ine EL4. European Journal of Immunology 28 3100-3109

Knorre A, Wagner M, Schaefer HE, Colledge WH and Pahl HL (2002) DeltaF508-CFTR causes constitutive NF-B activation through an ER-overload response in cystic fibrosis lungs. Biology and Chemistry 383 271-282

Knosel T, Emde A, Schluns K, Chen Y, Jurchott K, Krause M, Dietel M and Petersen I (2005) Immunoprofiles of 11 biomarkers using tissue microarrays identify prognostic subgroups in colorectal cancer. Neoplasia 7 741-747

Knowles H and Thanasou N (2008) Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte-osteoclast differentiation via induction of VEGF. Journal of Pathology in press

Knuefermann P, Chen P, Misra A, Shi SP, Abdellatif M and Sivasubramanian N (2002) Myotrophin/V-1, a protein upregulated in the failing human heart and in postnatal cerebellum converts NF-kB p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. Journal of Biological Chemistry 277 23888-23897

Knuefermann P, Chen P, Misra A, Shi SP, Abdellatif M and Sivasubramanian N (2002) Myotrophin/V-1, a protein up-regulated in the failing human heart and in postnatal cerebellum, converts NFkB p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. Journal of Biological Chemistry 277 23888-23897

Knuefermann P, Sakata Y, Baker JS, Huang CH, Sekiguchi K, Hardarson HS, Takeuchi O, Akira S and Vallejo JG (2004) Toll-like receptor 2 mediates Staphylococcus aureus-induced myocardial dysfunction and cytokine production in the heart. Circulation 110 3693-3698

Knuefermann P, Schwederski M, Velten M, Krings P, Ehrentraut H, Rudiger M, Boehm O, Fink K, Dreiner U Grohe C, Hoeft A, Baumgarten G, Koch A, Zacharowski K and Meyer R (2008) Bacterial DNA induces myocardial inflammation and reduces cardiomyocyte contractility: role of Toll-like receptor 9. Cardiovascular Research in press

Ko GJ, Kang YS, Han SY, Lee MH, SOng HK, Han KH, Kim HK, Han JY and Cha DR (2008) Pioglitazone attenuates diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. Nephrology, Dialysis and Transplantation in press

Ko HC, Kuo YH, Wei BL and Chiou WF (2005) Title?> Planta Med 71 514-519
Ko HM, Jung HH, Seo KH, Kang YR, Kim HA, Park SJ, Lee HK and Im SY (2006) Platelet-activating factor-induced NF-kB activation enhances VEGF expression through a decrease in p53 activity. FEBS Letters 580 3006-3012

Ko HM, Kang JH, Choi JH, Park SJ, Bai S and Im SY (2005) Platelet-activating factor induces matrix metalloproteinase-9 expression through Ca(2+)- or PI3K-dependent signaling pathway in a human vascular endothelial cell line. FEBS Letters 579 6451-6458

Ko HM, Kang JH, Jung B, Kim HA, Park SJ, Kim KJ, Kang YR, Lee HK and Im SY (2007) Critical role for matrix metalloproteinase-9 in platelet-activating factor-induced experimental tumor metastasis. International Journal of Cancer 120 1277-1283

Ko HM, Park YM, Jung B, Kim HA, Choi JH, Park SJ, Lee HK and Im SY (2005) Involvement of matrix metalloproteinase-9 in platelet-activating factor-induced angiogenesis. FEBS Letters 579 2369-2375

Ko HM, Seo KH, Han SJ, Ahn KY, Choi IH, Koh GY, Lee HK, Ra MS and Im SY (2002) Nuclear factor kB dependency of platelet-activating factor-induced angiogenesis. Cancer Research 62 1809-1814

Ko HW, Park KY, Kim H, Han PL, Kim YU, Gwag BJ and Choi EJ (1998) Ca2+-mediated activation of c-Jun N-terminal kinase and nuclear factor kB by NMDA in cortical cell cultures. Journal of Neurochemistry 71 1390-1395

Ko J, Kim IS, Jang SW, Lee YH, Shin SY, Min do S and Na DS (2002) Leukotactin-1/CCL15-induced chemotaxis signaling through CCR1 in HOS cells. FEBS Letters 515 159-164

Ko JH, Lee SJ and Lim KT (2005) 36kDa Glycoprotein isolated from Rhus verniciflua Stokes fruit has a protective activity to glucose/glucose oxidase-induced apoptosis in NIH/3T3 cells. Toxicology In Vitro 19 353-363
Ko JH, Lee SJ and Lim KT (2005) 116 kDa glycoprotein isolated from Ulmus davidiana Nakai (UDN) inhibits glucose/glucose oxidase (G/GO)-induced apoptosis in BNL CL.2 cells. Journal of Ethnopharmacology 100 339-346

Ko JS, Yang HR, Chang JY and Seo JK (2007) Lactobacillus plantarum inhibits epithelial barrier dysfunction and interleukin-8 secretion induced by tumor necrosis factor-alpha. World Journal of Gastroenterology 13 1962-1965

Ko S, Shi L, Kim S, Song CS and Chatterjee B (2008) Interplay of NF-kB and B-myb in the negative regulation of androgen receptor expression by TNFa. Molecular Endocrinology 22 273-286

Ko YG, Park H, Kim T, Lee JW, Park SG, Seol W, Kim JE, Lee WH, Kim SH, Park JE and Kim S (2001) A cofactor of tRNA synthetase, p43, is secreted to up-regulate proinflammatory genes. Journal of Biological Chemistry 276 23028-23033

Koay MA, Christman JW, Segal BH, Venkatakrishnan A, Blackwell TR, Holland SM and Blackwell TS (2001) Impaired pulmonary NF-kappaB activation in response to lipopolysaccharide in NADPH oxidase-deficient mice. Infection and Immunity 69 5991-5996

Koay MA, Christman JW, Wudel LJ, Allos T, Cheng DS, Chapman WC and Blackwell TS (2002) Modulation of endotoxin-induced NF-kB activation in lung and liver through TNF type 1 and IL-1 receptors. American Journal of Physiology: Lung Cell and Molecular Physiology 283 L1247-L1254

Kobashi C, Urakaze M, Kishida M, Kibayashi E, Kobayashi H, Kihara S, Funahashi T, Takata M, Temaru R, Sato A, Yamazaki K, Nakamura N and Kobayashi M ((2005) Adiponectin inhibits endothelial synthesis of interleukin-8. Circulation Research 97 1245-1252

Kobayashi A, Matsui M, Kubo T and Natori S (1993) Purification and characterization of a 59-kilodalton protein that specifically binds to NF-kB-binding motifs of the defense protein genes of Sarcophaga peregrina (the flesh fly). Molecular and Cellular Biology 13 4049-4056

Kobayashi H (2006) Endogenous anti-inflammatory substances, inter-alpha-inhibitor and bikunin. Biological Chemistry 387 1545-1549

Kobayashi H, Espinosa III R, Thirman MJ, Davis EM, Diaz MO, Le Beau MM, Rowley JD (1993) Variability of 11q23 rearrangements in hematopoietic cell lines identified with fluorescence in situ hybridization. Blood 81 3027-3033

Kobayashi H, Yagyu T, Kondo T, Kurita N, Inagaki K, Haruta S, Kawaguchi R, Kitanaka T, Sakamoto Y, Yamada Y, Kanayama N and Terao T (2005) Suppression of urokinase receptor expression by thalidomide is associated with inhibition of nuclear factor kB activation and subsequently suppressed ovarian cancer dissemination. Cancer Research 65 10464-10471

Kobayashi I, Yamamoto S, Nishi N, Tsuji K, Imayoshi M, Inada S, Ichiamaru T and Hamasaki Y (2004) Regulatory mechanisms of Th2 cytokine-induced eotaxin-3 production in bronchial epithelial cells: possible role of interleukin 4 receptor and nuclear factor-kB. Annals of Allergy, Asthma and Immunology 93 390-397

Kobayashi K, Hernandez LD, Galan JE, Janeway Jr CA, Medzhitov R and Flavell RA (2002) IRAK-M is a negative regulator of Toll-like receptor signaling. Cell 110 191-202

Kobayashi K, Kambe F, Kurokouchi K, Sakai T, Ishiguro N, Iwata H, Koga K and Seo H (1999) Effects of vector-averaged gravity on NF-kB activation in human osteoblast-like cells. Environmental Medicine 43 25-27

Kobayashi K, Matsumoto S, Morishima T, Kawabe T and Okamoto T (2000) Cimetidine inhibits cancer cell adhesion to endothelial cells and prevents metastasis by blocking E-selectin expression. Cancer Research 60 3978-3984

Kobayashi N, Kadono Y, Naito A, Matsumoto K, Yamamoto T, Tanaka S and Inoue J (2001) Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis. EMBO Journal 20 1271-1280

Kobayashi N, Mita SI, Yoshida K, Honda T, Kobayashi T, Hara K, Nakano S, Tsubokou Y and Matsuoka H (2003) Celiprolol activates eNOS through the PI3K-Akt pathway and inhibits VCAM-1 via NF-kB induced by oxidative stress. Hypertension 42 1004-1013

Kobayashi N, Yoshida K, Mita SI, Honda T, Hara K, Nakano S, Tsubokou Y and Matsuoka H (2004) Betaxolol stimulates eNOS production associated with LOX-1 and VEGF in Dahl salt-sensitive rats. Journal of Hypertension 22 1397-1402

Kobayashi O, Miwa H, Watanabe S, Tsujii M, Dubois RN and Sato N (2001) Cyclooxygenase-2 downregulates inducible nitric oxide synthase in rat intestinal epithelial cells. American Journal of Physiology: Gastrointestinal Liver Physiology 281 G688-G696

Kobayashi S, Nagino M, Komatsu S, Naruse K, Nimura Y, Nakanishi M and Sokabe M (2003) Stretch-induced IL-6 secretion from endothelial cells requires NF-kB activation. Biochemical and Biophysical Research Communications 308 306-312

Kobayashi S, Okamoto H, Iwamoto T, Toyama Y, Tomatsu T, Yamanaka H and Momohara S (2008) A role for the aryl hydrocarbon receptor and the dioxin TCDD in rheumatoid arthritis. Rheumatology (Oxford) in press

Kobayashi T, Okamoto N, Sawasaki T and Endo Y (2004) Detection of protein-DNA interactions in crude cellular extracts by fluorescence correlation spectroscopy. Analytical Biochemistry 332 58-66

Kobayashi Y and Takahashi N (2008) Genomic approaches to bone and joint diseases. Mutations of RANK, OPG and RANKL genes found in humans [Article in Japanese].  Clinical Calcium 18 202-209

Kobayashi Y and Udagawas N (2007) Mechanisms of alveolar bone remodeling {Japanese].Clinical Calcium 17 209-216

Kobayashi Y, Ueki S, Maheumuti B, Chiba T, Oyamda H, Saito N, Kanda A, Kayaba H and Chihara J (2005) Physiological levels of 15-deoxy-delta12,14-prostaglandin J2 prime eotaxin-induced chemotaxis on human eosinophils through peroxisome proliferator-activated receptor-gamma ligation. Journal of Immunology 175 5744-5750

Kobayashi Y, Ueyama S, Arai Y, Yoshida Y, Kaneda T, Sato T, Shin K, Kumegawa M and Hakeda Y (2004) The active metabolite of leflunomide, A771726, inhibits both the generation of and the bone-resorbing activity of osteoclasts by acting directly on cells of the osteoclast lineage. Journal of Bone and Mineral Metabolism 22 318-328

Kobielak A and Fuchs E (2006) Links between alpha-catenin, NF-kB, and squamous cell carcinoma in skin. Proceedings of the National Academy of Sciences USA 103 2322-2327

Kobayashi-Sakamoto M, Hirose K, Isogai E and Chiba I (2004) NF-kB-dependent induction of osteoprotegerin by Porphyromonas gingivalis in endothelial cells. Biochemical and Biophysical Research Communications 315 107-112

Kobayashi-Sakamoto M, Isogai E, Hirose K and Chiba I (2008) Role of alpha(v) integrin in osteoprotegerin-induced endothelial cell migration and proliferation. Microvascular Research in press

Kobori M, Nakayama N, Fukushima K, Ohnishi-Kameyama M, Ono H, Fukushima T, AKimoto Y, Masumoto S, Yukizaki C, Hoshi Y, Deguchi T and Yoshida M (2008) Bitter gourd suppresses lipopolysaccharide-induced inflammatory responses. Journal of Agricultural Food Chemsitry in press

Kobori M, Yang Z, Gong D, Heissmeyer V, Zhu H, Jung YK, Gakidis MA, Rao A, Sekine T, Ikegami F, Yuan C and Yuan J (2003) Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK complex. Cell Death & Differentiation 11 123-130

Kobori M, Yoshida M, Ohnishi-Kameyama M and Shinmoto H (2007) Ergosterol peroxide from an edible mushroom suppresses inflammatory responses in RAW264.7 macrophages and growth of HT29 colon adenocarcinoma cells. British Journal of Pharmacology 150 209-219

Kobuchi H, Roy S, Sen CK, Nguyen HG and Packer L (1999) Quercetin inhibits inducible ICAM-1 expression in human endothelial cells through the JNK pathway. American Journal of Physiology 277 C403-C411

Kocabas C, Katsenelson N, Kanswal S, Kennedy MN, Cui X, Blake MS, Segal DM and Akkoyunlu M (2007) Neisseria meningitidis type C capsular polysaccharide inhibits lipooligosaccharide-induced cell activation by binding to CD14. CellularMicrobiology in press

Kocer SS, Djuric PM, Bugallo MF, Simon SR and Matic M (2008) Transcriptional profiling of putative human epithelial stem cells. BMC Genomics 9 359

Koch A, Giembycz M, Ito K, Lim S, Jazrawi E, Barnes PJ, Adcock I, Erdmann E and Chung KF (2003) MAP-kinase modulation of NF-kB-induced GM-CSF release from human alveolar macrophages. American Journal of Respiratroy Cell and Molecular Biology 30 342-349

Koch A, Giembycz M, Stirling RG, Lim S, Adcock I, Wassermann K, Erdmann E and Chung KF (2004) Effect of smoking on MAP kinase-induced modulation of IL-8 in human alveolar macrophages. European Respiratory Journal 23 805-812

Koch E, Klaas CA, Rungeler P, Castro V, Mora G, Vichnewski W and Merfort I (2001) Inhibition of inflammatory cytokine production and lymphocyte proliferation by structurally different sesquiterpene lactones correlates with their effect on activation of NF-kB. Biochemical Pharmacology 62 795-801

Kochel T and Rice NR (1992) v-rel- and c-rel-protein complexes bind to the NF-kB site in vitro. Oncogene 7 567-572

Kochel T, Mushinski JF and Rice NR (1991) The v-rel and c-rel proteins exist in high molecular weight complexes in avian and murine cells. Oncogene 6 615-626

Kochi Y, Yamada R, Suzuki A, Harley JB, Shirasawa S, Sawada T, Bae SC, Tokuhiro S, Chang X, Sekine A, Takahashi A, Tsunoda T, Ohnishi Y, Kaufman KM, Kang CP, Kang C, Otsubo S, Yumura W, Mimori A, Koike T, Nakamura Y, Sasazuki T and Yamamoto K (2005) A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities. Nature Genetics 37 478-485

Kochlatyi S, Gibbons N and Mattana J (2002) Extracellular matrix oxidation modulates survival, NF-kB translocation, and MAPK activity in mesangial cells. Experimental and Molecular Pathology 73 191-197

Kocks C, Cho JH, Nehme N, Ulvila J, Pearson AM, Meister M, Strom C, Conto SL, Hetru C, Stuart LM, Stehle T, Hoffmann JA, Reichhart JM, Ferrandon D, Ramet M and Ezekowitz RA (2005) Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila. Cell 123 335-346

Koczan D, Drynda S, Hecker M, Drynda A, Guthke R, Kekow J and Thiesen HJ (2008) Molecular discrimination of responders and non-responders to anti-TNF-a therapy in rheumatoid arthritis by etanercept. Arthritis Research and Therapy 10 R50

Kodach LL, Bos CL, Duran N, Peppelenbosch MP, Ferreira CV and Hardwick JC (2006) Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells.
Carcinogenesis 27 508-516

Kodaki T, Izui K and Katsuki H (1983) Cell volume change of Escherichia coli under stringent control. Apparent increase of K+ in rel- cells. Biochimica et Biophysica Acta 761 223-230

Kode A, Yang SR and Rahman I (2006) Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells.Respiratory Research 7 132

Koduru PRK, Lichtman SM, Smilari TF, Sun T, Goh JC, Karp L, Hall W, Hashimoto S, Chiorazzi N and Broome JD (1993) Serial pheotypic, cytogenetic and molecular genetic studies in Richter’s syndrome: demonstration of lymphoma development from the chronic lymphocytic leukaemia cells. British Journal of Haematology 85 613-616

Koedel U, Angele B, Rupprecht T, Wagner H, Roggenkamp A, Pfister HW and Kirschning CJ (2003) Toll-like receptor 2 participates in mediation of immune response in experimental pneumococcal meningitis. Journal of Immunology 170 438-444

Koedood Zhao M, Wang Y, Murphy K, Yi J, Beckerle MCand Gilmore TD (1999) LIM domain-containing protein Trip6 can act as a co-activator for the v-Rel transcription factor. Gene Expression 8 207-217

Koenigsknecht-Talboo J and Landreth GE (2005) Microglial phagocytosis induced by fibrillar beta-amyloid and IgGs are differentially regulated by proinflammatory cytokines. Journal of Neuroscience 25 8240-8249

Koerber K, Sass G, Kiemer AK, Vollmar AM and Tiegs G (2002) In vivo regulation of inducible no synthase in immune-mediated liver injury in mice. Hepatology 36 1061-1069

Kofod-Olsen E, Ross-Hansen K, Mikkelsen JG and Hollsberg P (2008) Human herpesvirus 6B U19 protein is a PML-regulated transcriptional activator that localizes to nuclear foci in a PML-independent manner. Journal of General Virology 89 106-116

Koga T, Torigoshi T, Motokawa S, Miyashita T, Maeda Y, Nakamura M, Komori A, Aiba Y, Uemura T, Yatsuhashi H, Ishibashi H, Eguchi K, Migita K (2008) Serum amyloid A-induced IL-6 production by rheumatoid synoviocytes. FEBS Letters in press

Kogel D, Peters M, Konig HG, Hashemi SM, Bui NT, Arolt V, Rothermundt M and Prehn JH (2004) S100B potently activates p65/c-Rel transcriptional complexes in hippocampal neurons: Clinical implications for the role of S100B in excitotoxic brain injury. Neuroscience 127 913-920

Kogoshi H, Tohda S, Fu L, Koyama T and Nara N (2005) Effect of Notch ligands on in vitro sensitivity to chemo-therapeutic drugs in leukemia and lymphoma cells.Oncology Reports 14 723-726

Koh DC, Armugam A and Jeyaseelan K (2004) Sputa nerve growth factor forms a preferable substitute to mouse 7S-beta nerve growth factor. Biochemical Journal 383 149-158

Koh HS, Lee C, Lee KS, Ham CS, Seong RH, Kim SS and Jeon SH (2008) CD7 expression and galectin-1-induced apoptosis of immature thymocytes are directly regulated by NF-kB upon T-cell activation. Biochemical and Biophysical Research Communications in press

Koh JM, Lee YS, Kim YS, Kim DJ, Kim HH, Park JY, Lee KU and Kim GS (2006) Homocysteine enhances bone resorption by stimulation of osteoclast formation and activity through increased intracellular ROS generation. Journal of Bone and Mineral Research 21 1003-1011

Koh SH, Chang DI, Kim HT, Kim J, Kim MH, Kim KS, Bae I, Kim H, Kim DW and Kim SH (2005) Effect of 3-aminobenzamide, PARP inhibitor, on matrix metalloproteinase-9 level in plasma and brain of ischemic stroke model. Toxicology 214 131-139

Koh Y, Kang JL, Park W, Pack IS, Lee HS, Kim MJ and Lim CM (2001) Inhaled nitric oxide down-regulates intrapulmonary nitric oxide production in lipopolysaccharide-induced acute lung injury. Critical Care Medicine 29 1169-1174

Kohashi M, Ishimaru N, Arakaki R and Hayashi Y (2008) Effective treatment with oral administration of rebamipide in a mouse model of Sjögren’s syndrome. Arthritis and Rhematism 58 389-400

Kohlberg R (1991) Basic and clinical HIV-1 researchers target NF-kB protein. Journal of NIH Research 3 28-29

Kohlberg R (1997) Tangled pathways: new roles for NF-kB, TNF-a in apoptosis. Journal of NIH Research 9 29-32

Kohler HB, Knop J, Martin M, de Bruin A, Huchzermeyer B, Lehmann H, Kietzmann M, Meier B and Nolte I (1999) Involvement of reactive oxygen species in TNF-alpha mediated activation of the transcription factor NF-kB in canine dermal fibroblasts. Veterinary Immunology and Immunopathology 71 125-142

Kohlhaas SL, Craxton A, Sun X-M, Pinkoski MJ and Cohen GM 92007) Receptor-mediated apoptosis-inducing ligand (TRAIL)-induced apoptosis. Journal of Biological Chemistry 282 12831-12841

Koide M, Maeda H, Roccisana JL, Kawanabe N and Reddy SV (2003) CytokineRegulation and the signaling mechanism of osteoclast inhibitory peptide-1 (OIP-1/hSca) to inhibit osteoclast formation. Journal of Bone and Mineral Research 18 458-465

Koide N, Sugiyama T, Mori I, Mu MM, Yoshida T and Yokochi T (2003) C(2)-ceramide inhibits LPS-induced nitric oxide production in RAW 264.7 macrophage cells through down-regulating the activation of Akt. Journal of Endotoxin Research 9 85-90

Koike T, Shimada T, Fujii Y, Chen G, Tabei K, Namatame T, Yamagata M, Tajima A, Yoneda M, Terano A and Hiraishi H (2007) Up-regulation of TFF1 (pS2) expression by TNF-a in gastric epithelial cells.
Journal of Gastroenterology and Hepatology 22 936-942

Koike T, Yamagishi H, Hatanaka Y, Fukushima A, Chan JW, Xia Y, Fields M, Chandler P and Iwashima M (2003) A novel ERK dependent signaling process that regulates IL-2 expression in a late phase of T cell activation. Journal of Biological Chemistry 278 15685-15692

Koishi R, Yoshimura C, Kohama T and Serizawa N (2002) Leustroducsin B Activates Nuclear Factor-kappaB via the Acidic Sphingomyelinase Pathway in Human Bone Marrow-Derived Stromal Cell Line KM-102. Journal of Interferon and Cytokine Research 22 343-350

Koizumi N, Hatano E, Nitta T, Tada M, Harada N, Taura K, Ikai I and Shimahara Y (2005) Blocking of PI3K/Akt pathway enhances apoptosis induced by SN-38, an active form of CPT-11, in human hepatoma cells. International Journal of Oncology 26 1301-1306

Kojima H, Aizawa Y, Yanai Y, Nagaoka K, Takeuchi M, Ohta T, Ikegami H, Ikeda M and Kurimoto M (1999) An essential role for NF-kB in IL-18-induced IFN-gamma expression in KG-1 cells. Journal of Immunology 162 5063-5069

Kojima M, Morisaki T, Izuhara K, Uchiyama A, Matsunari Y, Katano M and Tanaka M (2000) Lipopolysaccharide increase cyclo-oxygenase-2 expression in a colon carcinoma cell line through nuclear factor-kB activation. Oncogene 19 1225-1231

Kojima T, Morikawa Y, Copeland NG, Gilbert DJ, Jenkins NA, Senba E and Kitamura T (2000) TROY, a newly identified member of the tumor necrosis factor receptor superfamily exhibits a homology with Edar and is expressed in embryonic skin and hair follicles. Journal of Biological Chemistry 275 20742-20747

Kokkinakis DM (2006) Methionine-stress: A pleiotropic approach in enhancing the efficacy of chemotherapy. Cancer Letters 233 195-207

Kokkinakis DM, Liu X, Chada S, Ahmed MM, Shareef MM, Singha UK, Yang S and Luo J (2004) Modulation of gene expression in human central nervous system tumors under methionine deprivation-induced stress. Cancer Research 64 7513-7525

Kokkinakis DM, Rushing EJ, Shareef MM, Ahmed MM, Yang S, Singha UK and Luo J (2004) Physiology and gene expression characteristics of carcinogen-initiated and tumor-transformed glial progenitor cells derived from the CNS of methylnitrosourea (MNU)-treated Sprague-Dawley rats. Journal of  Neuropathology and Experimental Neurology 63 1182-1199

Kokkola R, Andersson A, Mullins G, Ostberg T, Treutiger CJ, Arnold B, Nawroth P, Andersson U, Harris RA and Harris HE (2005) RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages. Scandinavian Journal of Immunology 61 1-9

Kokura S, Rhoads CA, Wolf RE, Yoshikawa T, Granger DN and Aw T (2001) NF-kB signaling in posthypoxic endothelial cells: relevance to E-selectin expression and neutrophil adhesion. Journal of Vascular Research 38 47-58

Kokura S, Wolf RE, Yoshikawa T, Granger DN and Aw TY (1999) Molecular mechanisms of neutrophil-endothelial cell adhesion induced by redox imbalance. Circulation Research 84 516-524

Kokura S, Wolf RE, Yoshikawa T, Ichikawa H, Granger DN and Aw TY (2000) Endothelial cells exposed to anoxia/reoxygenation are hyperadhesive to T-lymphocytes: kinetics and molecular mechanisms. Microcirculation 7 13-23

Kokura S, Yoshida N, Imamoto E, Ueda M, Ishikawa T, Uchiyama K, Kuchide M, Naito Y, Okanoue T and Yoshikawa T (2004) Anoxia/reoxygenation down-regulates the expression of E-cadherin in human colon cancer cell lines. Cancer Letters 211 79-87

Kokura S, Yoshida N, Ishikawa T, Higashihara H, Sakamoto N, Takagi T, Uchiyama K, Naito Y, Mazda O, Okanoue T and Yoshikawa T (2005) Interleukin-10 plasmid DNA inhibits subcutaneous tumor growth of Colon26 adenocarcinoma in mice. Cancer Letters 218 171-179

Kokura S, Yoshida N, Sakamoto N, Ishikawa T, Takagi T, Higashihara H, Nakabe N, Handa O, Naito Y and Yoshikawa T (2005) The radical scavenger edaravone enhances the anti-tumor effects of CPT-11 in murine colon cancer by increasing apoptosis via inhibition of NF-kB. Cancer Letters 228 223-233

Kokura S, Yoshida N, Ueda M, Imamoto E, Ishikawa T, Takagi T, Naito Y, Okanoue T and Yoshikawa T (2003) Hyperthermia enhances tumor necrosis factor alpha-induced apoptosis of a human gastric cancer cell line. Cancer Letters 20 89-96

Kol A, Bourcier T, Lichtman AH and Libby P (1999) Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages. Journal of Clinical Investigation 103 571-577

Kol A, Lichtman AH, Finberg RW, Libby P and Kurt-Jones EA (2000) Cutting edge: heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells. Journal of Immunology 164 13-17

Kolenko V, Bloom T, Rayman P, Bukowski R, Hsi E and Finke J (1999) Inhibition of NF-kB activity in human T lymphocytes induces caspase-dependent apoptosis without detectable activation of caspase-1 and -3. Journal of Immunology 163 590-598

Kolesnick R and Golde DW (1994) The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling. Cell 77 325-328

Kolev K, Skopal J, Simon L, Csonka E, Machovich R and Nagy Z (2003) Matrix metalloproteinase-9 expression in post-hypoxic human brain capillary endothelial cells: H(2)O(2) as a trigger and NF-kB as a signal transducer. Thrombosis and Haemostosis 90 528-537

Kollet JI and Petro TM (2006) IRF-1 and NF-kB p50/cRel bind to distinct regions of the proximal murine IL-12 p35 promoter during costimulation with IFN-gamma and LPS. Molecular Immunology 43 623-633

Kollisch G, Kalali BN, Voelcker V, Wallich R, Behrendt H, Ring J, Bauer S, Jakob T, Mempel M and Ollert M (2005) Various members of the Toll-like receptor family contribute to the innate immune response of human epidermal keratinocytes. Immunology 113 531-541

Kolonics A, Apati A, Janossy J, Brozik A, Gati R, Schaefer A and Magocsi M (2001) Activation of Raf/ERK1/2 MAP kinase pathway is involved in GM-CSF-induced proliferation and survival but not in erythropoietin-induced differentiation of TF-1 cells. Cell Signaling 13 743-754

Kolyada AY, Fedtsov A and Madias NE (2001) 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors upregulate inducible NO synthase expression and activity in vascular smooth muscle cells. Hypertension 38 1024-1029

Komander D and Barford D (2007) Structure of the A20 OTU domain and mechanistic insights into deubiquitination. Biochemical Journal 409 77-85

Komander D, Lord CJ, Scheel H, Swift S, Hofmann K, Ashworth A and Barford D (2008) The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module. Molecular Cell 29 451-464

Komarova EA, Krivokrysenko V, Wang K, Neznanov N, Chernov MV, Komarov PG, Brennan ML, Golovkina TV, Rokhlin O, Kuprash DV, Nedospasov SA, Hazen SR, Feinstein E and Gudkov AV (2005) p53 is a suppressor of inflammatory response in mice. FASEB Journal 19 130-132

Komarova EA, Neznanov N, Komarov PG, Chernov MV, Wang K and Gudkov AV (2003) p53 inhibitor PFTalpha can suppress heat shock and glucocorticoid signaling pathways. Journal of Biological Chemistry 278 15465-15468

Komatsu H, Hoshino A, Funayama M, Kawahara K and Obata F (2003) Oxidative modulation of the glutathione-redox couple enhances lipopolysaccharide-induced interleukin 12 P40 production by a mouse macrophage cell line, J774A.1. Free Radical Research 37 293-299

Komatsu T, Takeuchi K, Yokoo J and Gotoh B (2004) C and V proteins of Sendai virus target signaling pathways leading to IRF-3 activation for the negative regulation of interferon-beta production. Virology 325 137-148

Komatsu W, Ishihara K, Murata M, Saito H and Shinohara K (2003) Docosahexaenoic acid suppresses nitric oxide production and inducible nitric oxide synthase expression in interferon-gamma plus lipopolysaccharide-stimulated murine macrophages by inhibiting the oxidative stress. Free Radical Biology and Medicine 34 1006-1016

Komine K, Kuroishi T, Ozawa A, Komine Y, Minami T, Shimauchi H and Sugawara S (2007) Cleaved inflammatory lactoferrin peptides in parotid saliva of periodontitis patients. Molecular Immunology 44 1498-1508

Komine M, Rao LS, Kaneko T, Tomic-Canic M, Tamaki K, Freedberg IM and Blumenberg M (2000) Inflammatory versus proliferative processes in epidermis. Tumor necrosis factor alpha induces K6b keratin synthesis through a transcriptional complex containing NFkB and C/EBPb. Journal of Biological Chemistry 275 32077-32088

Komine M, Watabe Y, Shimaoka S, Sato F, Kake K, Nishina H, Ohtsuki M, Nakagawa H and Tamaki K (1999) The action of a novel vitamin D3 analogue, OCT, on immunomodulatory function of keratinocytes and lymphocytes. Archives of Dermatological Research 291 500-506

Komninou D, Ayonote A, Richie JP Jr and Rigas B (2003) Insulin resistance and its contribution to colon carcinogenesis. Experimental Biology and Medicine 228 396-405

Komiya T, Miura K, Tsukamoto J, Okamura M, Tamada S, Asai T, Tashiro K, Kuwabara N, Iwao H and Yoshikawa J (2004) Possible involvement of nuclear factor-kB inhibition in the renal protective effect of oral adsorbent AST-120 in a rat model of chronic renal failure. International Journal of Molecular Medicine 13 133-138

Komjati K, Besson VC and Szabo C (2005) Poly (ADP-ribose) polymerase inhibitors as potential therapeutic agents in stroke and neurotrauma. Curr Drug Targets CNS Neurol Disord 4 179-194

Komura E, Tonetti C, Penard-Lacronique V, Chagraoui H, Lacout C, Lecouedic JP, Rameau P, Debili N, Vainchenker W and Giraudier S (2005) Role for the nuclear factor kB pathway in transforming growth factor-beta1 production in idiopathic myelofibrosis: possible relationship with FK506 binding protein 51 overexpression.Cancer Research 65 3281-3289

Komori J, Marusawa H, Machimoto T, Endo Y, Kinoshita K, Kou T, Haga H, Ikai I, Uemoto S and Chiba T (2008) Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma. Hepatology 47 888-896

Komuro H, Olee T, Kuhn K, Quach J, Brinson DC, Shikhman A, Valbracht J, Creighton-Achermann L and Lotz M (2001) The osteoprotegerin/receptor activator of nuclear factor kB/receptor activator of nuclear factor kB ligand system in cartilage. Arthritis & Rheumatism 44 2768-2776

Komura H, Uchiba M, Mizuochi Y, Arai M, Harada N, Katsuya H and Okajima K (2007) Antithrombin inhibits lipopolysaccharide-induced tumour necrosis factor-alpha production by monocytes in vitro through inhibition of Egr-1 expression. Journal of Thrombois and Haemostosis in press

Kon A, Vindevoghel L, Kouba DJ, Fujimura Y, Uitto J and Mauviel A (1999) Cooperation between SMAD and NF-kB in growth factor regulated type VII collagen gene expression. Oncogene 18 1837-1844

Konda R, Sugimura J, Sohma F, Katagiri T, Nakamura Y and Fujioka T (2008) Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1a and nuclear factor kB is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure. Journal of Urology in press

Kondo A, Mogi M, Koshihara Y and Togari A (2001) Signal transduction system for interleukin-6 and interleukin-11 synthesis stimulated by epinephrine in human osteoblasts and human osteogenic sarcoma cells. Biochemical Pharmacology 61 319-326

Kondo T, Higashiyama Y, Goto S, Iida T, Cho S, Iwanaga M, Mori K, Tani M and Urata Y (1999) Regulation of gamma-glutamylcysteine synthetase expression in response to oxidative stress. Free Radical Research 31 325-334

Kondo T, Kitazawa R, Yamaguchi and Kitazaz S (2007) Dexamethasone promotes osteoclastogenesis by inhibiting osteoprotegerin through multiple levels. Journal ofCellular Biochemistry in press

Kondo Y, Fukuda K, Adachi T, Nishida T (2008) Inhibiton by a selective IkB kinase-2 inhibtor of interleukin-1-induced collagen degradation by corneal fibroblast in three-dimensional culture. Invest Ophthalmol Vis Sci 49 4850-4857

Kondoh M, Nagashima F, Suzuki I, Harada M, Fujii M, Asakawa Y and Watanabe Y (2005) Induction of apoptosis by new ent-kaurene-type diterpenoids isolated from the New Zealand liverwort Jungermannia species. Planta Medica 71 1005-1009

Konduri SD, Yanamandra N, Dinh DH, Olivero WC, Gujrati M, Foster DC, Kisiel W and Rao JS (2003) Physiological and chemical inducers of tissue factor pathway inhibitor-2 in human glioma cells. International Journal of Oncology 22 1277-1283

Kong AN, Yu R, Lei W, Mandlekar S, Tan TH and Ucker DS (1998) Differential activation of MAPK and ICE/Ced-3 protease in chemical-induced apoptosis: the role of oxidative stress in the regulation of mitogen-activated protein kinases (MAPKs) leading to gene expression and survival or activation of caspases leading to apoptosis. Restor Neurol Neurosci 12 63-70

Kong D, Li Y, Wang Z, Banerjee S and Sarkar FH (2007) Inhibition of angiogenesis and invasion by 3,3′-diindolylmethane is mediated by the nuclear factor-kB downstream target genes MMP-9 and uPA that regulated bioavailability of vascular endothelial growth factor in prostate cancer. Cancer Research 67 3310-3319

Kong D, Park EJ, Stephen AG, Calvani M, Cardellina JH, Monks A, Fisher RJ, Shoemaker RH and Melillo G (2005) Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity. Cancer Research 65 9047-9055

Kong D, Wang Z, Sarkar SH, Li Y, Banerjee S, Salignan A, Kim HR, Cher ML and Sarkar FH (2008) PDGF-D over-expression contributes to epithelial-mesenchymal transition of PC3 prostate cancer cells. Stem Cells in press

Kong LN, Zuo PP, Mu L, Liu YY and Yang N (2005) Gene expression profile of amyloid beta protein-injected mouse model for Alzheimer disease. Acta Pharmacologica Sinica26 666-672

Kong X, Wang X, Xu W, Beherea S, Hellermann G, Kumar A, Lockey RF, Mohapatra S adn Hohapatra SS (2008) Natriuretic peptide receptor a as a novel anticancer target. Cancer Research 68 249-256

Kong XN, Yan HX, Chen L, Dong LW, Tang W, Liu Q, Yu LX, Huang DD, Liu SQ, Liu H, Wu MC and Wang HY (2007) LPS-induced down-regulation of signal regulatory protein alpha contributes to innate immune activation in macrophages. Journal of ExperimentalMedicine 204 2719-2731

Konig HG, Kogel D, Rami A and Prehn JH (2005) TGF-beta1 activates two distinct type I receptors in neurons: implications for neuronal NF-kB signaling. Journal of Cell Biology 168 1077-1086

Konishi H, Nakatsuka M, Chekir C, Noguchi S, Kamada Y, Sasaki A and Hiramatsu Y (2004) Advanced glycation end products induce secretion of chemokines and apoptosis in human first trimester trophoblasts. Human Reproduction 19 2156-2162

Konish M, Nishitani C, Mitsuzawa H, Shimizu T, Sano H, Harimaya A, Fujii N, Himi T and Kuroki T (2006) Alloiococcus otitidis is a ligand for collectins and Toll-like receptor 2, and its phagocytosis is enhanced by collectins. European Journal ofImmunology 36 1527-1536

Konishi T, Sasaki S, Watanabe T, Kitayama J and Nagawa H (2006) Overexpression of hRFI inhibits 5-fluorouracil-induced apoptosis in colorectal cancer cells via activation of NF-kB and upregulation of BCL-2 and BCL-XL. Oncogene 25 3160-3169

Kono H, Rusyn I, Bradford BU, Connor HD, Mason RP and Thurman RG (2000) Allopurinol prevents early alcohol-induced liver injury in rats. Journal of Pharmacology and Experimental Therapeutics 293 296-303

Kono H, Rusyn I, Uesugi T, Yamashina S, Connor HD, Dikalova A, Mason RP and Thurman RG (2001) Diphenyleneiodonium sulfate, an NADPH oxidase inhibitor, prevents early alcohol-induced liver injury in the rat. American Journal of Physiology: Gastrointestinal and Liver Physiology 280 G1005-G1012

Kono H, Wheeler MD, Rusyn I, Lin M, Seabra V, Rivera CA, Bradford BU, Forman DT and Thurman RG (2000) Gender differences in early alcohol-induced liver injury: role of CD14, NF-kB, and TNF-a. American Journal of Physiology: Gastrointestinal and Liver Physiology 278 G652-G661

Konsman JP, Vigues S, Mackerlova L, Bristow A and Blomqvist A (2004) Rat brain vascular distribution of interleukin-1 type-1 receptor immunoreactivity: Relationship to patterns of inducible cyclooxygenase expression by peripheral inflammatory stimuli. Journal of Comparative Neurology 472 113-129

Konson A, Mahajna JA, Danon A, Rimon G and Agbaria R (2006) The involvement of nuclear factor-kappa B in cyclooxygenase-2 overexpression in murine colon cancer cells transduced with herpes simplex virus thymidine kinase gene. Cancer Gene Therapy 13 1093-1104

Konstantinopoulos PA, Vandoros GP, Karamouzis MV, Gkermpesi M, Sotiropoulou-Bonikou G and Papvassiliou AG (2007) EGF-R is expressed and AP-1 and NF-kB are activated in stromal myofibroblasts surrounding colon adenocarcinomas paralleling expression of COX-2 and VEGF. Cellualr Oncology 29 477-482

Konstantinopoulos PA, Vandoros GP, Sotiropoulou-Bonikou G, Kominea A and Papvassiliou AG (2007) NF-kB/PPARg and/or AP-1/PPARgamma ‘on/off’ switches and induction of CBP in colon adenocarcinomas: correlation with COX-2 expression.International Journal of Colorectal Disease 22 57-68

Köntgen F, Grumont RJ, Strasser A, Metcalf D, Li R, Tarlinton D and Gerondakis S (1995) Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity and interleukin-2 expression. Genes & Development 9 1965-1977

Kontny E, Kurowska M, Szczepanska K and Maslinski W (2000) Rottlerin, a PKC isozyme-selective inhibitor, affects signaling events and cytokine production in human monocytes. Journal of Leukocyte Biology 67 249-258

Kontou M, Adelfalk C, Hirsch-Kauffmann M and Schweiger M (2003) Suboptimal action of NF-kB in Fanconi anemia cells results from low levels of thioredoxin. Biol Chem 384 1501-1507

Kontou M, Will RD, Adelfalk C, Wittig T, Poustka A, Hirsch-Kauffmann M and Schweiger M (2004) Thioredoxin, a regulator of gene expression. Oncogene 23 2146-2152

Konturek PC, Brzozowski T, Walter B, Burnat G, Hess T, Hahn EG and Konturek SJ (2006) Ghrelin-induced gastroprotection against ischemia-reperfusion injury involves an activation of sensory afferent nerves and hyperemia mediated by nitric oxide.European Journal of Pharmacology 536 171-181

Konturek PC, Kania J, Konturek JW, Nikiforuk A, Hahn EG and Konturek SJ (2003) H. pylori infection, atrophic gastritis, cytokines, gastrin, COX-2, PPARgamma and impaired apoptosis in gastric carcinogenesis. Med Sci Monit 9 SR53-SR66

Konturek PC, Nikiforuk A, Kania J, Raithel M, Hahn EG and Muhldorfer S (2004) Activation of NFkB represents the central event in the neoplastic progression associated with Barrett’s esophagus: a possible link to the inflammation and overexpression of COX-2, PPARg and growth factors. Dig Dis Sci 49 1075-1083

Koo HJ, Song YS, Kim HJ, Lee YH, Hong SM, Kim SJ, Kim BC, Jin C, Lim CJ and Park EH (2004) Antiinflammatory effects of genipin, an active principle of gardenia. European Journal of Pharmacology 495 201-208

Koo HN, Hong SH, Seo HG, Yoo TS, Lee KN, Kim NS, Kim CH and Kim HM (2003) Inulin stimulates NO synthesis via activation of PKC-a and protein tyrosine kinase, resulting in the activation of NF-kB by IFN-g-primed RAW 264.7 cells. Journal of Nutritional Biochemistry 14 598-605

Koo HN, Jeong HJ, Park JH, Moon G, Chae HJ, Kim HR, Kim CH, Seo SB, An NH and Kim HM (2001) Kunbi-Boshin-Hangam-Tang stimulates nitic oxide production through activation of nuclear factor-kB. Immunopharmacology and Immunotoxicology 23 175-186

Koo JW and Duman RS (2008) IL-1 is an essential mediator of the antineurogenic and anhedonic effects of stress. Proceedings of the National Academy of Sciences USA in press

Koo SW, Casper KA, Otto KB, Gira AK and Swerlick RA (2003) Iron chelators inhibit vcam-1 expression in human dermal microvascular endothelial cells. Journal of Investigative Dermatology 120 871-879

Koo TH, Lee JH, Park YJ, Hong YS, Kim HS, Kim KW and Lee JJ (2001) A sesquiterpene lactone, costunolide, from Magnolia grandiflora inhibits NF-kB by targeting IkB phosphorylation. Planta Medica 67 103-107

Kooistra T, Verschuren L, van der Weij J, Koenig W, Toet K, Princen HM and Kleemann R (2006) Fenofibrate reduces atherogenesis in ApoE*3Leiden mice: evidence for multiple antiatherogenic effects besides llowering plasma cholesterol.Arteriosclerosis, Thrombosis & Vascular Biology 26 2322-2330

Koon HW, Zhao D, Zhan Y, Simeonidis S, Moyer MP and Pothoulakis C (2005) Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves PKCdelta activation. Journal of Pharmacology and Experimental Therapeutics 314 1393-1400

Koong A, Chen E, Mivechi N, Denko N, Stambrook P and Giaccia A (1994) Hypoxic activation of NF-kB is mediated by a Ras and Ras signaling pathway and does not involve MAP kinase (ERK1 or ERK2). Cancer Research 54 5273-5279

Koong AC, Chen EY and Giacca AJ (1994) Hypoxia causes the activation of nuclear factor kB through the phosphorylation of IkBa on tyrosine residues. Cancer Research 54 1425-1430

Kopecky-Bromberg SA, Martinex-Sobrido L, Frieman M, Baric RA and Palese P (2006) SARA coronavirus proteins ORF 3B, ORF 6, and nucleocapsid function as interferon antagonists Journal of Virology in press

Kopp E and Ghosh S (1994) Inhibition of NF-kB by sodium salicylate and aspirin. Science 265 956-959

Kopp E and Ghosh S (1995) NF-kB and Rel proteins in innate immunity. Advances in Immunology 58 1-27

Kopp E, Medzhitov R, Carothers J, Xiao C, Douglas I, Janeway CA and Ghosh S (1999) ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway. Genes & Development 13 2059-2071

Kopp EB and Medzhitov R (1999) The Toll-receptor family and control of innate immunity. Current Opinions in Immunology 11 13-18

Koppel H, Yard BA, Christ M, Wehling M and Van Der Woude FJ (2003) Modulation of angiotensin II-mediated signalling by heparan sulphate glycosaminoglycans. Nephrol Dial Transplant 18 2240-2247

Korashy HM and El-Kadi AO (2007) The role of redox-sensitive transcription factors NF-kappaB and AP-1 in the modulation of the Cyp1a1 gene by mercury, lead, and copper. Free Radical Biology and Medicine in press

Korashy HM and El-Kadi AO (2008) Reply to Dvorak and Pavek, Letter to the Editor, regarding “The role of redox-sensitive transcription factors NF-kB and AP-1 in the modulation of Cyp1a1 gene by mercury, lead, and copper” Free Radical Biology and Medicine in press

Korbelik M, Sun J and Cecic I (2005) Photodynamic therapy-induced cell surface expression and release of heat shock proteins: relevance for tumor response. Cancer Research 65 1018-1026

Korber B, Okayama A, Donnelly R, Tachibana N and Essex M (1991) Polymerase chain reaction analysis of defective human T-cell leukemia virus type I proviral genomes in leukemic cells of patients with adult T-cell leukemia. Journal of Virology 65 5471-5476

Korchynskyi O, Dechering KJ, Sijbers AM, Olijve W and ten Dijke P (2003) Gene array analysis of bone morphogenetic protein type I receptor-induced osteoblast differentiation. Journal of Bone & Mineral Research 18 1177-1185

Korcok J, Raimundo LN, Du X, Sims SM and Dixon SJ (2005) P2Y6 nucleotide receptors activate NF-kB and increase survival of osteoclasts. Journal of Biological Chemistry 280 16909-16915

Korcok J, Raimundo LN, Ke HZ, Sims SM and Dixon SJ (2004) Extracellular nucleotides act through P2X7 receptors to activate NF-kB in osteoclasts. Journal of Bone and Mineral Research 19 642-651

Kordes U, Krappmann D, Heissmeyer V, Ludwig WD and Scheidereit C (2000) Transcription factor NF-kB is constitutively activated in acute lymphoblastic leukemia cells. Leukemia 14 399-402

Kordula T, Bugno M, Rydel RE and Travis J (2000) Mechanism of interleukin-1- and tumor necrosis factor alpha -dependent regulation of the alpha 1-antichymotrypsin gene in human astrocytes. Journal of Neuroscience 20 7510-7516

Korhonen R, Korpela R and Moilanen E (2002) Signalling mechanisms involved in the induction of inducible nitric oxide synthase by Lactobacillus rhamnosus GG, endotoxin, and lipoteichoic acid. Inflammation 26 207-214

Korhonen R, Kosonen O, Korpela R and Moilanen E (2004) The expression of COX2 protein induced by Lactobacillus rhamnosus GG, endotoxin and lipoteichoic acid in T84 epithelial cells. Lett Appl Microbiol 39 19-24

Korkmaz A, Topal T and Oter S (2007) Pathophysiological aspects of cyclophosphamide and ifosfamide induced hemorrhagic cystitis; implication of reactive oxygen and nitrogen species as well as PARP activation. Cell Biology and Toxicology in press

Korkolopoulou P,Levidou G, Saetta AA, El-Habr E, Eftichiadis C, Demenagas P, Thymara I, Xiromeritis K, Boviatsis E, Thomas-Tsagli E, Panayotidis I and Patsouris E (2008) Expression of nuclear factor-kB in human astrocytomas: relation to pIkBa, vascular endothelial growth factor, Cox-2, microvascular characteristics, and survival. Human Pathology in press

Korn SH, WOuters EFM, Vos N and Janssen-Heininger YMW (2001) Cytokine-induced activation of nuclear factor-kB is inhibited by hydrogen peroxide through oxidative inactivation of IkB kinase. Journal of Biological Chemistry 276 35693-35700

Korner M, Rattner A, Mauxion F, Sen R and Citri Y (1993) A brain-specific transcription activator. Neuron 3 563-572

Körner M, Tarantino N and Debré P (1991) Constitutive activation of NF-kB in human thymocytes. Biochemical and Biophysical Research Communications 181 80-86

Korobko EV, Saschenko LP, Prockhorchouk EB, Korobko IV, Gnuchev NV and Kiselev SL (1999) Resistance to tumor necrosis factor induced apoptosis in vitro correlates with high metastatic capacity of cells in vivo. Immunology Letters 67 71-76

Korobowicz A (2006) Biology of tumor necrosis factor type alpha (TNF-a) [Article in Polish]. Polski Merkuriusz Lekarski 21 358-361

Korus M, Mahon GM, Cheng L and Whitehead IP (2002) p38 MAPK-mediated activation of NF-kB by the RhoGEF domain of Bcr. Oncogene 21 4601-4612

Kos O, Castro V, Murillo R, Poveda L and Merfort I (2005) Ent-kaurane glycosides and sesquiterpene lactones of the hirsutinolide type from Vernonia triflosculosa.Phytochemistry 67 62-69

Kos O, Lindenmeyer MT, Tubaro A, Sosa S and Merfort I (2005) Sequiterpene lactones from Arnica montana inhibit NF-kB (tentative title). Planta Medica 71 1044-1052

Kosalec I and Pepeljnjak S (2004) Chemistry and biological effects of gliotoxin [Article in Croatian]. Arh Hig Rada Toksikol 55 313-320

Kosco KA< Cerignoli F, WIlliams S< Abraham RT andMustelin T (2007) SKAP55 modulates T cell antigen receptor-induced activation of the Ras-Erk-AP1 pathway by binding RasGRP1. Molecular Immunology in press

Koseki M, Hirano KI, Masuda D, Ikegami C, Tanaka M, Ota A, Sandoval JC, Nakagawa-Toyama Y, Sato SB, Kobayashi T, Shimada Y, Ohno-Iwashita Y, Matsuura F, Shimomura I and Yamashita S (2006) Increased lipid rafts and accelerated lipopolysaccharide-induced tumor necrosis factor alpha secretion in ABCa1-deficient macrophages.Journal of Lipid Research in press

Koseki T, Inohara N, Chen S, Carrio R, Merino J, Hottiger MO, Nabel GJ and Nunez G (1999) CIPER, a novel NF- kB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10. Journal of Biological Chemistry 274 9955-9961

Koski GK, Lyakh LA, Cohen PA and Rice NR (2001) CD14+ monocytes as dendritic cell precursors: diverse maturation-inducing pathways lead to common activation of NF-kB/RelB. Critical Reviews in Immunology 21 179-189

Koskinen PK, Kallio EA, Tikkanen JM, Sihvola RK, Hayry PJ and Lemstrom KB (1999) Cytomegalovirus infection and cardiac allograft vasculopathy. Transpl Infect Dis 1 115-126

Kostadinova RM, Nawrocki AR, Frey FJ and Frey BM (2005) Tumor necrosis factor alpha and phorbol 12-myristate-13-acetate down-regulate human 11beta-hydroxysteroid dehydrogenase type 2 through p50/p50 NF-kB homodimers and Egr-1. FASEB Journal 19 650-652

Kota S, Sabbah A, Chang TH, Harnack R, Xiang Y, Meng X and Bose S (2008) Role of human beta defensin-2 during tumor necrosis factor-a/NF-kB mediated innate anti-viral response against human respiratory syncytial virus. Journal of Biological Chemistry in press

Kotake Y, Sang H, Miyajima T and Wallis GL (1998) Inhibition of NF-kB, iNOS mRNA COX2 mRNA, and COX catalytic activity by phenyl-N-tert-butylnitrone (PBN). Biochimica et Biophysica Acta 1448 77-84

Kotani J, Avallone NJ, Lin E, Goshima M, Gandhi K, Lowry SF and Calvano SE (2003) Fas-mediated neutrophil apoptosis and associated A1 protein expression during systemic inflammation are regulated independently of both tumor necrosis factor receptors. Shock 19 201-207

Kotarsky K, Antonsson L, Owman C and Olde B (2003) Optimized reporter gene assays based on a synthetic multifunctional promoter and a secreted luciferase. Analytical Biochemistry 316 208-215

Koteish A, Yang S, Lin H, Huang X and Diehl AM (2002) Chronic ethanol exposure potentiates lipopolysaccharide liver injury despite inhibiting Jun N-terminal kinase and caspase 3 activation. Journal of Biological Chemistry 277 13037-13044

Kothe H, Dalhoff K, Rupp J, Muller A, Kreuzer J, Maass M and Katus HA (2000) Hydroxymethylglutaryl coenzyme A reductase inhibitors modify the inflammatory response of human macrophages and endothelial cells infected with Chlamydia pneumoniae. Circulation 101 1760-1763

Kothny-Wilkes G, Kulms D, Luger TA, Kubin M and Schwarz T (1999) Interleukin-1 protects transformed keratinocytes from tumor necrosis factor-related apoptosis-inducing ligand- and CD95-induced apoptosis but not from ultraviolet radiation-induced apoptosis. Journal of Biological Chemistry 274 28916-28921

Kothny-Wilkes G, Kulms D, Poppelmann B, Luger TA, Kubin M and Schwarz T (1998) Interleukin-1 protects transformed keratinocytes from tumor necrosis factor-related apoptosis-inducing ligand. Journal of Biological Chemistry 273 29247-29253

Kotla S, Peng T, Bumgarner RE and Gustin KE (2008) Attenuation of the type I interferon response in cells infected with human rhinovirus. Virology in press

Kotokorpi P, Gardmo C, Nystrom CS and Mode A (2004) Activation of the glucocorticoid receptor or liver X receptors interferes with growth hormone induced akr1b7 gene expression in rat hepatocytes. Endocrinology 145  5704-5713

Kouba DJ, Chung KY, Nishiyama T, Vindevoghel L, Kon A, Klement JF, Uitto J and Mauviel A (1999) Nuclear factor-kB mediates TNF-a inhibitory effect on alpha 2(I) collagen (COL1A2) gene transcription in human dermal fibroblasts. Journal of Immunology 162 4226-4234

Kouba DJ, Nakano H, Nishiyama T, Kang J, Uitto J and Mauviel A (2001) Tumor necrosis factor-alpha induces distinctive NF-kB signaling within human dermal fibroblasts. Journal of Biological Chemistry 276 6214-6224

Koubovec D, Berghe WV, Vermeulen L, Haegeman G and Hapgood JP (2004) Medroxyprogesterone acetate downregulates cytokine gene expression in mouse fibroblast cells. Molecular and Cellular Endocrinology 221 75-85

Kougias P, Wei D, Rice PJ, Ensley HE, Kalbfleisch J, Williams DL and Browder IW (2001) Normal human fibroblasts express pattern recognition receptors for fungal (1–>3)-beta-D-glucans. Infection and Immunity 69 3933-3938

Koul D, Takada Y, Shen R, Aggarwal BB and Yung WK (2006) PTEN enhances TNF-induced apoptosis through modulation of nuclear factor-kB signaling pathway in human glioma cells. Biochemical and Biophysical Research Communications 350 463-471

Koul D, Yao Y, Abbruzzese JL, Yung WK and Reddy SA (2001) Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkB activation without interfering with the IkB degradation pathway. Journal of Biological Chemistry 276 11402-11408

Koulich E, Nguyen T, Johnson K, Giardina C and D’Mello S (2001) NF-kB is involved in the survival of cerebellar granule neurons: association of IkBbeta phosphorylation with cell survival. Journal of Neurochemistry 76 1188-1198

Kourelis K, Papads T, Vandoros G, Goumas P and Sotiropoulou-Bonikou G (2007) Glottic versus supraglottic tumors: differential molecular profile. European Archives ofOtorhinolaryngology in press

Kourelis K, Sotiropoulou-Bonikou G, Vandoros G, Repanti M, Varakis I and Goumas P (2007) Coordinated upregulation of COX-2 and NF-kB is a steady feature of laryngeal carcinogenesis.
ORL Journal of Otorhinolaryngology and Related Specialties 69 181-189

Kouroedov A, Eto M, Joch H, Volpe M, Luscher TF and Cosentino F (2004) Selective inhibition of protein kinase C{beta}2 prevents acute effects of high glucose on vascular cell adhesion molecule-1 expression in human endothelial cells. Circulation 110 91-96

Kourylko O, Fradette C, Arcand M and du Souich P (2006) Modulation of CYP1A2 and CYP3A6 catalytic activities by serum from rabbits with a turpentine-induced inflammatory reaction and IL-6. Drug Metabolism and Disposition 34 27-35

Koutroubas G, Merika M and Thanos D (2007) Bypassing the requirements for epigenetic modifications in gene transcription by increasing enhancer strength. Molecular and Cellular Biology in press

Kovacich JC, Boyle EM, Jr., Morgan EN, Canty TG, Jr., Farr AL, Caps MT, Frank N, Pohlman TH and Verrier ED (1999) Inhibition of the transcriptional activator protein nuclear factor kB prevents hemodynamic instability associated with the whole-body inflammatory response syndrome. Journal of Thoracic and Cardiovascular Surgery 118 154-162

Kovacs B, Parry RV, Ma Z, Fan E, Shivers DK, Freiberg BA, Thomas AK, Rutherford R, Rumbley CA, Riley JL and Finkel TH (2005) Ligation of CD28 by its natural ligand CD86 in the absence of TCR stimulation induces lipid raft polarization in human CD4 T cells.
Journal of Immunology 175 7848-7854

Kovacs DA, Chakraborty-Sett S, Ramirez SH, Sniderhan LF, Williamson AL and Maggirwar SB (2004) Mechanism of NF-kB inactivation induced by survival signal withdrawal in cerebellar granule neurons. European Journal of Neuroscience 20 345-352

Kovalenko A, Chable-Bessia C, Cantarella G, Israel A, Wallach D and Courtois G (2003) The tumour suppressor CYLD negatively regulates NF-kB signalling by deqbiquitination. Nature 424 801-805

Kovalenko A and Wallach D (2006) If the prophet coes not come to the mountain: dynamics of signaling complexes in NF-kB activation. Molecular Cell 22 433-436

Kovalovich K, DeAngelis RA, Li W, Furth EE, Ciliberto G and Taub R (2000) Increased toxin-induced liver injury and fibrosis in interleukin-6-deficient mice. Hepatology 31 149-159

Kovall RA and Hendrickson WA (2004) Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA. EMBO Journal 23 3441-3451

Kovjazin R, Eldar T, Patya M, Vanichkin A, Lander HM and Novogrodsky A (2003) Ferrocene-induced lymphocyte activation and antitumor activity is mediated by redox-sensitive signaling. FASEB Journal 17 467-469

Kowalik TF, Wing B, Haskill JS, Azizkhan JC, Baldwin Jr AS and Huang E-S (1993) Multiple mechanisms are implicated in the regulation of NF-kB activity during human cytomegalovirus infection. Proceedings of the National Academy of Sciences USA 90 1107-1111

Kowalski MP and Pier GB (2004) Localization of cystic fibrosis transmembrane conductance regulator to lipid rafts of epithelial cells is required for Pseudomonas aeruginosa-induced cellular activation. Journal of Immunology 172 418-425

Kowluru RA (2005) Effect of advanced glycation end products on accelerated apoptosis of retinal capillary cells under in vitro conditions. Life Sciences 76 1051-1060

Kowluru RA, Chakrabarti S and Chen S (2005) Re-institution of good metabolic control in diabetic rats and activation of caspase-3 and nuclear transcriptional factor (NF-kB) in the retina. Acta Diabetol 41 194-199

Kowluru RA and Kanwar M (2007) Effects of curcumin on retinal oxidative stress and inflammation in diabetes. Nutrition & Metabolism (London) 4 8

Kowluru RA, Koppolu P, Chakrabarti S and Chen S (2003) Diabetes-induced activation of nuclear transcriptional factor in the retina, and its inhibition by antioxidants. Free Radical Research 37 1169-1180

Kowluru RA, Kolluru A and Kanwar M (2006) Small molecular weight G-protein, H-Ras, and retinal endothelial cell apoptosis in diabetes. Molecular and CellularBiochemistry in press

Kowluru RA and Odenbach S (2004) Role of interleukin-1{beta} in the pathogenesis of diabetic retinopathy. British Journal of Opthalmology 88 1343-1347

Kowluru RA and Odenbach S (2004) Role of interleukin-1beta in the development of retinopathy in rats: effect of antioxidants. Investigative Ophthalmology and Visual Science 45 4161-4166

Koyama H, Suzuki Y, Ohwada Y and Saito Y (1976) Reticulendotheliosis group virus pathogenic to chicken isolated from material infected with turkey herpesvirus (HVT). Avian Diseases 20 429-434

Koyama S (2003) Differential expression of intracellular apoptotic signaling molecules in tumor and tumor-infiltrating lymphocytes during development of invasion and/or metastasis of gastric carcinoma. Dig Dis Sci 48 2290-2300

Koyama T, Sakamoto N, Tanabe Y, Nakagawa M, Itsui Y, Takeda T, Kakinuma S, Sekine Y, Maekawa S, Yanai Y, Kurimoto M and Watanabe M (2006) Divergent activities of interferon-alpha subtypes against intracellular hepatitis C virus replication.Hepatology Research 34 41-49

Koyanagi M, Hijikata M, Watashi K, Masui O and Shimotohno K (2005) Centrosomal P4.1-associated protein is a new member of transcriptional coactivators for nuclear factor kB. Journal of Biological Chemistry 280 12430-12437

Koyano S, Saito Y, Nagano M, Maekawa K, Kikuchi Y, Murayama N, Fujino T, Ozawa S, Nakajima T, Matsumoto K, Saito H and Sawada JI (2003) Functional analysis of three genetic polymorphisms in the glucocorticoid receptor gene. Journal of Pharmacology and Experimental Therapeutics 307 110-116

Kozak W, Wrotek S and Kozak A (2005) Pyrogenicity of CpG-DNA in mice: Role of interleukin-6, cyclooxygenases, and nuclear-factor-kB. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 290 R871-R880

Koziak-Holbro M, Joyce C, Gluck A, Kinzel B, Muller M, Tshopp C, Mathison JC, Davis CN and Gram H (2007) IRAK-4 kinase activity is required for interleukin-1 (IL-1) receptor- and Toll-like receptor 7-mdiated signaling and gene expression. Journal of Biological Chemistry 282 13552-13560

Koziczak-Holbro M, Gluck A, Tschopp C, Mathison JC and Graim H (2008) IRAK-4 kinase activity-dependent and -independent regulation of lipopolysaccharide-inducible genes. European Journal of Immunology 38 788-796

Koziczak-Holbro M, Joyce C, Gluck A, Kinzel B, Muller M and Graam H (2007) Solving the IRAK-4 enigma: application of kinase-dead knock-in mice. Ernst Schering Foundation Symposium Proceedings 3 63-82

Kozlov IA, Kubareva EA and Shabarova ZA (1998) Use of synthetic oligonucleotides for inhibition of factor NF-kB. Molecular Biology (Moscow) 32 389-400

Kozlov S, Mounkes L, Cutler D, Sullivan T, Hernandez L, Levy N, Rottman J and Stewart CL (2005) Mutations in the mouse Lmna gene causing progeria, muscular dystrophy and cardiomyopathy. Novartis Foundation Symposium 264 246-258

Kozlov SV, Dobrovolskaia MA, Rice NR, Stewart CL and Vogel SN (2003) A novel cell-based system for the rapid quantitative evaluation of (anti)-inflammatory potential of test substances. Journal of Immunological Methods 281 51-63

Kraatz J, Clair L, Bellingham J, Wahlstrom K, Rodriguez JL and West MA (1998) Lipopolysaccharide pretreatment produces macrophage endotoxin tolerance via a serum-independent pathway. Journal of Trauma 45 684-691

Kracklauer MP and Schmidt C (2003) At the crossroads of SUMO and NF-κB. Molecular Cancer 2 39

Kraft C, Jenett-Siems K, Kohler I, Tofern-Reblin B, Siems K, Bienzle U and Eich E (2002) Antiplasmodial activity of sesquilignans and sesquineolignans from Bonamia spectabilis. Phytochemistry 60 167-173

Kraft M, Adler KB, Ingram JL, Crews AL, Atkinson TP, Cairns CB, Krause DC and Chu HW (2008) Mycoplasma pneumoniae induces airway epithelial cell expression of MUC5AC in asthma. European Respiratory Journal 31 43-46

Kraft S and Bieber T (2001) Fc epsilon ri-mediated activation of transcription factors in antigen- presenting cells. International Archives of Allergy and Immunology 125 9-15

Kraft S, Katoh N, Novak N, Koch S and Bieber T (2001) Unexpected functions of FcepsilonRI on antigen-presenting cells. International Archives of Allergy and Immunology 124 35-37

Kraft S, Novak N, Katoh N, Bieber T and Rupec RA (2002) Aggregation of the high-affinity IgE receptor Fc(epsilon)RI on human monocytes and dendritic cells induces NF-kB activation. Journal of Investigative Dermatology 118 830-837

Krakauer T (2004) Molecular therapeutic targets in inflammation: cyclooxygenase and NF-kB. Current Pharmaceutical Design 3 317-324

Krakauer T and Buckley M (2008) The potency of anti-oxidants in attenuating superantigen-induced proinflammatory cytokines correlates with inactivation of NF-kB. Immunopharmacology and Immunotoxicology 30 163-179

Kralisch S, Klein J, Lossner U, Bluher M, Paschke R, Stumvoll M and Fasshauer M (2005) Proinflammatory adipocytokines induce TIMP-1 expression in 3T3-L1 adipocytes. FEBS Letters 579 6417-6422

Kralisch S, Sommer G, Stangl V, Kohler U, Kratzsch J, Stepan H, Faber R, Schubert A, Lossner U, Vietzke A, Bluher M, Stumvoll M and Fasshauer M (2007) Secretory products from human adipocytes impair endothelial function via nuclear factor kB.Atherosclerosis in press

Kralova J, Liss AS, Bargmann W and Bose Jr HR (1998) AP-1 factors play an important role in transformation induced by the v-rel oncogene. Molecular and Cellular Biology 18 2997-3009

Kralova J, Liss AS, Bargmann W, Pendleton C, Varadarajan J, Ulug E and Bose Jr HR Jr (2002) Differential regulation of the inhibitor of apoptosis ch-IAP1 by v-rel and the proto-oncogene c-rel. Journal of Virology 76 11960-11970

Kralova J, Schatzle JD, Bargmann W and Bose Jr HR (1994) Transformation of avian fibroblasts overexpressing the c-rel proto-oncogene and a variant of c-rel lacking 40 C-terminal amino acids. Journal of Virology 68 2073-2083

Kralova J, Schatzle JD, Liss AS, Bargmann W and Bose Jr HR (1996) Synergistic stimulation of avian IkBa by rel and fos/jun factors. Oncogene 12 2595-2604

Kramer AA, Salhab KF, Shafii AE, Norman J, Carey LC and Mendez C (1999) Induction of tolerance to hemorrhagic or endotoxic shock involves activation of NF-kB. Journal of Surgical Research 83 89-94

Kramer BW, Kaemmerer U, Kapp M, Herbst D, Marx A, Berg D, Groneck PA and Speer CP (2005) Decreased expression of angiogenic factors in placentas with chorioamnionitis after preterm birth. Pediatric Research 58 607-612

Kramer G, Steiner GE, Sokol P, Mallone R, Amann G and Marberger M (2003) Loss of CD38 correlates with simultaneous up-regulation of human leukocyte antigen-DR in benign prostatic glands, but not in fetal or androgen-ablated glands, and is strongly related to gland atrophy. BJU International 91 409-416

Kramer HF and Goodyear LJ (2007) Exercise, MAPK, and NF-kB signaling in skeletal muscle. Journal of Applied Physiology in press

Kramer OH, Baus D, Knauer SK, Stein S, Jager E, Stauber RH, Grez M, Pfitzner E and Heinzel T (2006) Acetylation of Stat1 modulates NF-kB activity. Genes andDevelopment 20 473-485

Krammer PH, Arnold R and Lavrik IN (2007) Life and death in peripheral T cells.Nature Reviews Immunology 7 532-542

Kranzhofer R, Browatzki M, Schmidt J and Kubler W (1999) Angiotensin II activates the proinflammatory transcription factor nuclear factor-kappaB in human monocytes. Biochemical and Biophysical Research Communications 257 826-828

Kranzhofer R, Schmidt J, Pfeiffer CA, Hagl S, Libby P and Kubler W (1999) Angiotensin induces inflammatory activation of human vascular smooth muscle cells. Arteriosclerosis, Thrombosis and Vascular Biology 19 1623-1629

Krappmann D, Emmerich F, Kordes U, Scharschmidt E, Dorken B and Scheidereit C (1999) Molecular mechanisms of constitutive NF-kB/Rel activation in Hodgkin/Reed Sternberg cells. Oncogene 18 943-953

Krappmann D, Patke A, Heissmeyer V and Scheidereit C (2001) B-cell receptor- and phorbol ester-induced NF-kB and c-Jun N-terminal kinase activation in B cells requires novel protein kinase C’s. Molecular and Cellular Biology 21 6640-6650

Krappmann D nad Scheidereit C (2005) A pervasive role of ubiquitin conjugation in activation and termination of IkB kinase pathways. EMBO Reports 6 321-326

Krappmann D, Wegener E, Sunami Y, Esen M, Thiel A, Mordmuller B and Scheidereit C (2004) The IkB kinase complex and NF-kB act as master regulators of lipopolysaccharide-induced gene expression and control subordinate activation of AP-1. Molecular and Cellular Biology 24 6488-6500

Krappmann D, Wulczyn FG and Scheidereit C (1996) Different mechanisms control signal-induced degradation and basal turnover of the NF-kB inhibitor IkBa in vivo. EMBO Journal 15 6716-6726

Krasnow SW, Zhang LQ, Leung KY, Osborn L, Kunkel S and Nabel GJ (1991) Tumor necrosis factor-alpha, interleukin 1, and phorbol myristate acetate are independent activators of NF-kB which differnetially activates T cells. Cytokine 3 372-379

Kratsovnik E, Bromberg Y, Sperling O and Zoref-Shani E (2005) Oxidative stress activates transcription factor NF-kB-mediated protective signaling in primary rat neuronal cultures. Journal of Molecular Neuroscience 26 27-32

Krauer KG, Belzer DK, Liaskou D, Buck M, Cross S, Honjo T and Sculley T (1998) Regulation of interleukin-1b transcription by Epstein-Barr virus involves a number of latent proteins via their interaction with RBP. Virology 252 418-430

Kraus AC, Ferber I, Bachmann SO, Specht H, Wimmel A, Gross MW, Schlegel J, Suske G and Schuermann M (2002) In vitro chemo- and radio-resistance in small cell lung cancer correlates with cell adhesion and constitutive activation of AKT and MAP kinase pathways. Oncogene 21 8683-8695

Kraus DM and Bulla GA (1999) Defective NF-kB signaling in dedifferentiated hepatoma cells. Somatic Cell Molecular Genetics 25 275-286

Kraus J, Borner C, Giannini E and Hollt V (2003) The role of nuclear factor kB in tumor necrosis factor-regulated transcription of the human mu-opioid receptor gene. Molecular Pharmacology 64 876-884

Kraus M, Aimzhanov MB, Rajewsky N and Rajewsky K (2004) Survival of resting mature B lymphocytes depends on BCR signaling via the Iga/b heterodimer. Cell 117 787-800

Kravchenko VV, Kaufmann GF, Mathison JC, Scott DA, Katz AZ, Grauer DC, Lehmann M, Jeijler MM, Janda KD and Eulevitch RJ (2008) Modulation of gene expression via disruption of NF-kB signaling by a bacterial small molecule. Science in press

Kravchenko VV, Mathison JC, Schwamborn K, Mercurio F, Ulevitch RJ (2003) IKKi/IKKe plays a key role in integrating signals induced by pro-inflammatory stimuli. Journal of Biological Chemistry 278 26612-26619

Kray AE, Carter RS, Pennington KN, Gomez RJ, Sanders LE, LLanes JM, Khan WN, Ballard DW and Wadzinski BE (2005) Positive regulation of IkB kinase signaling by protein serine/threonine phosphatase 2A. Journal of Biological Cehmistry 280 35974-35982

Krebs M and Roden M (2004) Nutrient-induced insulin resistance in human skeletal muscle. Current Medicinal Chemistry 11 901-908

Krehan A, Ausuini H, Bocher O, Grein S, Wirkner U and Walter P (2000) Transcription factors Ets1, NFkB and Sp1 are major determinants of the promoter activity of the human protein dinase CK2a gene. Journal of Biological Chemistry 275 18327-18336

Kreja L, Liedert A, Schmidt C, Claes L and Ignatius A (2007) Influence of receptor activator of nuclear factor (NF)-kB ligand (RANKL), macrophage-colony stimulating factor (M-CSF) and fetal calf serum on human osteoclast formation and activity.Journal of Molecular Histology in press

Krejsek J, Kunes P, ANdrys C, Holicka M, Novosad J, Kudlova M and Kolackova M (2005) Innate immunity, receptors for exogenous and endogenous danger patterns in immunopathogenesis of atlherosclerosis–part 1: identification of danger signals by innate immunity [Article in Czech]. Cas Lek Cesk 144 785-789

Kretz-Remy C and Arrigo AP (2003) Modulation of the chymotrypsin-like activity of the 20S proteasome by intracellular redox status: effects of glutathione peroxidase-1 overexpression and antioxidant drugs. Biology and Chemistry 384 589-595

Kretz-Remy C and Tanguay RM (1999) SUMO/sentrin: protein modifiers regulating important cellular functions. Biochemistry and Cell Biology 77 299-309

Kretz-Remy C, Bates E and Arrigo AP (1998) Amino acid analogs activate NF-kB through redox-dependent IkB-a degradation by the proteasome without apparent IkB-a phosphorylation: Consequence on HIV-1 long terminal repeat activation. Journal of Biological Chemistry 273 3180-3191

Kretzmann NA, Fillmann H, Mauriz JL, Marroni CA, Marroni N, Gonzalez-Gallego J and Tunon MJ (2008) Effects of glutamine on proinflammatory gene expression and activation of nuclear factor kappa B and signal transducers and activators of transcription in TNBS-induced colitis. Inflammatory Bowel Disease in press

Kretzschmar M, Meisternernst M, Scheidereit C, Li G and Roeder RG (1992) Transcriptional regulation of the HIV-1 promoter by NF-kB in vitro. Genes & Development 6 761-774

Kreuz S, Siegmund D, Rumpf JJ, Samel D, Leverkus M, Janssen O, Hacker G, Dittrich-Breiholz O, Kracht M, Scheurich P and Wajant H (2004) NFkB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP. Journal of  Cell Biology 166 369-380

Kreuz S, Siegmund D, Scheurich P and Wajant H (2001) NF-kB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling. Molecular and Cellular Biology 21 3964-3973

Kreydiyyeh SI and Al-Sadi R (2004) The signal transduction pathway that mediates the effect of interleukin-1 beta on the Na(+)-K(+)-ATPase in LLC-PK(1) cells. Pflugers Archives 448 231-238

Krieg AM (2002) CpG motifs in bacterial DNA and their immune effects. Annual Reviews of Immunology 20 709-760

Krieg AM (2000) The role of CpG motifs in innate immunity. Current Opinions in Immunology 12 35-43

Krieg AM, Guga P and Stec W (2003) P-chirality-dependent immune activation by phosphorothioate CpG oligodeoxynucleotides. Oligonucleotides 13 491-499

Kriehuber E, Bauer W, Charbonnier AS, Winter D, Amatschek S, Tamandl D, Schweifer N, Stingl G and Maurer D (2005) The balance between NF-kB and JNK/AP-1 activity controls dendritic cell life and death. Blood 106 175-183

Kriete A, Mayo KL, Yalamachili N, Beggs W, Bender P, Kari C and Rodeck U (2008) Cell autonomous expression of inflammatory genes in biologically aged fibroblasts associated with elevated NF-kB activity. Immune Ageing 5 in press

Krikos A, Laherty CD and Dixit VM (1992) Transcriptional activation of the tumor necrosis factor a-inducible zinc finger protein, A20, is mediated by kB elements. Journal of Biological Chemistry 267 17971-17976

Krillov A, Kistler B, Mostoslavsky R, Cedar H, Wirth T and Bergman Y (1996) A role for nuclear NF-kB in B-cell-specific demethylation of the Igk locus. Nature Genetics 13 435-441

Krippner-Heidenreich A, Tubing F, Bryde S, Willi S, Zimmermann G and Scheurich P (2002) Control of receptor-induced signaling complex (RISC) formation by the kinetics of ligand/receptor interaction. Journal of Biological Chemistry 277 44155-44163

Krisanaprakornkit S, Kimball JR and Dale BA (2002) Regulation of human beta-defensin-2 in gingival epithelial cells: the involvement of mitogen-activated protein kinase pathways, but not the NF-kB transcription factor family. Journal of Immunology 168 316-324

Krishna S, Jensen MH and Sneppen K (2006) Minimal model of spiky oscillations in NF-kB signaling. Proceedings of the National Academy of Sciences USA 103 10840-10845

Krishnamoorthy RR, Crawford MJ, Chaturvedi MM, Jain SK, Aggarwal BB, Al-Ubaidi MR and Agarwal N (1999) Photo-oxidative stress down-modulates the activity of nuclear factor-kB via involvement of caspase-1, leading to apoptosis of photoreceptor cells. Journal of Biological Chemistry 274 3734-3743

Krishnan VA, Schatzle JD, Hinojos CM and Bose Jr HR (1995) Structure and regulation of the gene encoding avian IkB-a. Gene 166 261-266

Krishnegowda G, Hajjar AM, Zhu J, Douglass EJ, Uematsu S, Akira S, Woods AS and Gowda DC (2005) Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols (GPIs) of Plasmodium falciparum: cell signaling receptors, GPI structural requirement, and regulation of GPI activity. Journal of Biological Chemistry 280 8606-8616

Kristof AS, Fielhaber J, Triantafillopoulos A, Menoto S and Joss J (2006) Phosphatidylinositol 3-kinase-dependent suppression of the human inducible nitric oxide synthase promoter is mediated by FKHRL1. Journal of Biological Chemistry 281 23958-23968

Kristof AS, Marks-Konczalik J and Moss J (2001) Mitogen-activated protein kinases mediate AP-1-dependent human inducible nitric oxide synthase promoter activation. Journal of Biological Chemistry 276 8445-8452

Kroczynska B and Carbone M (2006) Cross reactivity between many anti-human antibodies for their hamster homologs provide the tools to study the signal transduction pathway activated by asbestos and SV40 in the malignant mesothelioma model. Molecular Carcinogenesis 45 537-542

Kroemer JA and Webb BA (2006) Divergences in protein activity and cellular localization within the Campoletis sonorensis Ichnovirus vankyrin family. Journal ofVirology 80 12219-12228

Krohn K, Rozovsky I, Wals P, Teter B, Anderson CP and Finch CE (1999) Glial fibrillary acidic protein transcription responses to transforming growth factor-beta1 and interleukin-1beta are mediated by a nuclear factor-1-like site in the near-upstream promoter. Journal of Neurochemistry 72 1353-1361

Kroismayr R, Baranyi U, Stehlik C, Dorfleutner A, Binder BR and Lipp J (2004) HERC5, a HECT E3 ubiquitin ligase tightly regulated in LPS activated endothelial cells. Journal of Cell Science 117 4749-4756

Kroll M, Arenzana-Seisdedos F, Bachelerie F, Thomas D, Friguet B and Conconi M (1999) The secondary fungal metabolite gliotoxin targets proteolytic activities of the proteasome. Chemistry and Biology 6 689-698

Kroll M, Conconi M, Desterro MJP, Marin A, Thomas D, Friguet B, hay RT, Virelizier J-L, Arenzana-Seisdedos F and Rodriguez MS (1997) The carboxy-terminus of IkBa determines susceptibility to degradation by the catalytic core of the proteasome. Oncogene 15 1841-1850

Kroll M, Margottin F, Kohl A, Renard P, Durand H, Condcordet JP, Bachelerie F, Arenzana-Seisdedos F and Benarous R (1999) Inducible degradation of IkBa by the proteasome requires interaction with the F-box protein h-bTrCP. Journal of Biological Chemistry 274 7941-7945

Kroncke KD (2003) Nitrosative stress and transcription. Biol Chem 384 1365-1377

Krontiris TG (1995) Minisatellites and human disease. Science 269 1682-1683

Kroon ME, Koolwijk P, van der Vecht B and van Hinsbergh VW (2001) Hypoxia in combination with FGF-2 induces tube formation by human microvascular endothelial cells in a fibrin matrix: involvement of at least two signal transduction pathways. Journal of Cell Science 114 825-833

Krueger A. Bauma S, Krammer PH and Kirchhoff S (2001) FLICE-inhibitory ptoteins: regulators of death receptor-mediated apoptosis. Molecular and Cellular Biology 21 8247-8254

Kruez S, Siegmund D, Scheurich P, Wajant H (2001) NF-kB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling. Molecular and Cellular Biology 21 3964-3973

Krug LT, MOser JM, Dickerson SM and Speck SH (2007) Inhibition of NF-kB activation in vivo impairs establishment of gammaherpesvirus latency. PLoS Pathogenesis 3 e11

Krull M, Bockstaller P, Wuppermann FN, Klucken AC, Muhling J, Schmeck B, Seybold J, Walter C, Maass M, Rosseau S, Hegemann JH, Suttorp N and Hippenstiel S (2006) Mechanisms of Chlamydophila pneumoniae mediated GM-CSF release in human bronchial epithelial cells. American Journal of Respiratory Cell and Molecular Biology 34 375-382

Krull M, Klucken AC, Wuppermann FN, Fuhrmann O, Magerl C, Seybold J, Hippenstiel S, Hegemann JH, Jantos CA and Suttorp N (1999) Signal transduction pathways activated in endothelial cells following infection with Chlamydia pneumoniae. Journal of Immunology 162 4834-4841

Krunkosky TM, Fischer BM, Martin LD, Jones N, Akley NJ and Adler KB (2000) Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro. Signaling pathways controlling surface and gene expression. American Journal of Respiratory Cell and Molecular Biology 22 685-692

Kruppa G, Thoma B, Machleidt T, Wiegmann K and Krönke M (1992) Inhibition of tumor necrosis factor (TNF) mediated NF-kB activation by selective blockade of the human 55-kd TNF receptor. Journal of Immunology 148 3152-3157

Krushel LA, Cunningham BA, Edelman GM and Crossin KL (1999) NF-kB activity is induced by neural cell adhesion molecule binding to neurons and astrocytes. Journal of Biological Chemistry 274 2432-2439

Kruyt FA (2008) TRAIL and cancer therapy. Cancer Letters in press

Krzesz R, Wagner AH, Cattaruzza M and Hecker M (1999) Cytokine-inducible CD40 gene expression in vascular smooth muscle cells is mediated by nuclear factor kB and signal transducer and activation of transcription-1. FEBS Letters 453 191-196

Ku CL, Dupuis-Girod S, Dittrich AM, Bustamante J, Santos OF, Schulze I, Bertrand Y, Couly G, Bodemer C, Bossuyt X, Picard C and Casanova JL (2005) NEMO mutations in 2 unrelated boys with severe infections and conical teeth. Pediatrics 115 e615-e619

Ku CL, Yang K, Bustamante J, Puel A, von Bernuth H, Santos OF, Lawrence T, Chang HH, Al-Mousa H, Picard C and Casanova JL (2005) Inherited disorders of human Toll-like receptor signaling: immunological implications. Immunology Reviews 203 10-20

Ku PT, You M, Bose HR (2000) Role and regulation of Rel/NF-kB activity in anti-immunoglobulin-induced apoptosis in WEHI-231 B lymphoma cells. Cellular Signaling 12 245-253

Kuai J, Nickbarg E, Wooters J, Qiu Y, Wang J and Lin LL (2003) Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin beta receptor reveals a novel mechanism of apoptosis. Journal of Biological Chemistry 278 14363-14369

Kuang AA, Novak D, Kang S-M, Bruhn K and Lenardo MJ (1993) Interaction between NF-kB- and serum response factor-binding elements activates an interleukin-2 receptor a-chain enhancer specifically in T lymphocytes. Molecular and Cellular Biology 13 1536-1545

Kuang PP, Berk JL, Rishikof DC, Foster JA, Humphries DE, Ricupero DA and Goldstein RH (2002) NF-kB induced by IL-1beta inhibits elastin transcription and myofibroblast phenotype. Am J Physiol Cell Physiol 283 C58-C65

Kuang PP and Goldstein RH (2003) Regulation of elastin gene transcritpion by interleukin-1b-induced C/EBPb isoforms. American Journal of Physiology: Cell Physiology 285 L1147-L1152

Kuang PP and Goldstein RH (2005) Regulation of elastin gene transcription by proteasome dysfunction. American Journal of Physiology: Cell Physiology 289 C766-C773

Kuang X, Yan M, Liu N, Scofield VL, Qiang W, Cahill J, Lynn WS and Wong PK (2005) Control of Atm-/- thymic lymphoma cell proliferation in vitro and in vivo by dexamethasone. Cancer Chemotherapy and Pharmacology 55 203-212

Kubo-Murai M, Hazeki K, Nigorikawa K, Omoto T, Inoue N and Hazeki O (2007) IRAK-4-dependent degradation of IRAK-1 is a negative feedback signal for TLR-mediated NF-kB activation. Journal of Biochemistry (Tokyo) in press

Kuboki S, Okaya T, Shuster R, Blanchard J, Denenberg A, Wong H and Lentsch AB (2007) Hepatocyte NF-kB activation is hepatoprotective during ischemia/reperfusion injury and is augmented by ischemic hypothermia. American Journal of Physiology:Gastrointestinal and Liver Physiology 292 G201-G207

Kuboki S, Schuster R, Blanchard J, Pritts TA, Wong H and Lentsch AB (2007) Role of heat shock protein 70 in hepatic ischemia/reperfusion injury in mice. AmericanJournal of Physiology: Gastrointestinal and Liver Physiology 292 G1141-G1149

Kubonishi I, Niiya K, Yamashita M, Yano S, Abe T, Ohtsuki Y, Miyoshi I (1986) Characterization of a new human lymphoma cell line (RC-K8) with t(11;14) chromosome abnormality. Cancer 58 1453-1460

Kubota K, Wakabayashi K and Matsuoka T (2003) Proteome analysis of secreted proteins during osteoclast differentiation using two different methods: Two-dimensional electrophoresis and isotope-coded affinity tags analysis with two-dimensional chromatography. Proteomics 3 616-626

Kubo E, Singh DP and Akagi Y (2005) Gene expression profiling of diabetic and galactosaemic cataractous rat lens by microarray analysis. Diabetologica 48 790-798

Kubo M, Morisaki T, Matsumoto K, Tasaki A, Yamanaka N, Nakashima H, Kuroki H, Nakamura K, Nakamura M and Katano M (2004) Paclitaxel probably enhances cytotoxicity of natural killer cells against breast carcinoma cells by increasing perforin production. Cancer Immunology and Immunotherapy 54 468-476

Kubo-Murai M, Hazeki K, Nigorikawa K, Omoto T, Inoue N and Hazeki O (2007) IRAK-4-dependent degradation of IRAK-1 is a negative feedback signal for TLR-mediated NF-kB activation. Journal of Biochemistry in press

Kubo-Murai M, Hazeki K, Sukenobu N, Yoshikawa K, Nigorikawa K, Inoue K, Yamamoto T, Matsumoto M, Seya T, Inoue N and Hazeki O (2006) Protein kinase Cdelta binds TIRAP/Mal to participate in TLR signaling. Molecular Immunology 44 2257-2264

Kubota A, Hasegawa K, Suguro T and Koshihara Y (2004) Tumor necrosis factor-alpha promotes the expression of osteoprotegerin in rheumatoid synovial fibroblasts. Journal of Rheumatology 31 426-435

Kubota K and Gay NJ (1995) The dorsal protein enhances the biosynthesis and stability of the Drosophila IkB homologue cactus. Nucleic Acids Research 23 3111-3118

Kubota T, Kushikata T, Fang J and Krueger JM (2000) Nuclear factor-kB inhibitor peptide inhibits spontaneous and interleukin-1beta-induced sleep. American Journal of Physiology: Regulatory, Integrative and Compartative Physiology 279 R404-R413

Kubota T, Miyagishima M, Frye CS, Alber SM, Bounoutas GS, Kadokami T, Watkins SC, McTiernan CF and Feldman AM (2001) Overexpression of tumor necrosis factor-alpha activates both anti- and pro-apoptotic pathways in the myocardium. Journal of Molecular and Cellular Cardiology 33 1331-1344

Kubota Y, Sasaki S, Kubota H, Tatsura H and Kohri K (2001) A study on the mechanism of the spermatogenic damage after vasectomy in rats [Article in Japanese]. Nippon Hinyokika Gakkai Zasshi 92 13-22

Kucharczak J, Simmons MJ, Fan Y and Gelinas C (2003) To be, or not to be: NF-kB is the answer – role of Rel/NF-kB in the regulation of apoptosis. Apoptosis 22 8961-8982

Kudo S and Fukuda M (1995) Tissue-specific expression of human leukosialin (CD43) gene is regulated by DNA methylation. Abstract of the American Society for Cell Biology, Molecular Biology of the Cell 78a 456

Kudo T, Lu H, Wu JY, Graham DY, Casola A and Yamaoka Y (2005) Regulation of RANTES promoter activation in gastric epithelial cells infected with Helicobacter pylori. Infection and Immunity 73 7602-7612

Kudo T, Lu H, Wu JY, Ohno T, Wu MJ, Genta RM, Graham DY and Yamaoka T (2007) Pattern of transcription factor activation in Helicobacter pylori-infected Mongolian gerbils. Gastroenterology 132 1024-1038

Kudo Y, Guardavaccaro D, Santamaria PG, Koyama-Nasu R, Latres E, Bronson R, Yamasaki L and Pagano M (2004) Role of F-box protein {beta}Trcp1 in mammary gland development and tumorigenesis. Molecular and Cellular Biology 24 8184-8194

Kuefer R, Genze F, Zugmaier W, Hautmann RE, Rinnab L, Gschwend JE, Angelmeier M, Estrada A and Buechele B (2007) Antagonistic effects of sodium butyrate and N-(4-hydroxyphenyl)-retinamide on prostate cancer. Neoplasia 9 246-253

Kuenze P, Kiefer S, Koryakina A and Hamburger M (2008) Promotion of cell death or neurite outgrowth in PC-12 and N2a cells by the fungal alkaloid militarinone A depends on basal expression of p53. Apoptosis 13 364-376

Kufer TA, Banks DJ and Philpott DJ (2006) Innate immune sensing of microbes by Nod proteins. Annals of the New York Academy of Sciences 1072 19-27

Kufer TA, Kremmer E, Adam AC, Philpott DJ and Sansonetti PJ (2007) The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction. Cellular Microbiology in press

Kufer TA, Kremmer E, Banks DJ and Philpott DJ (2006) Role for erbin in bacterial activation of nod2. Infection and Immunity 74 3115-3124

Kuhn DJ, Burns AC, Kazi A and Ping Dou Q (2004) Direct inhibition of the ubiquitin-proteasome pathway by ester bond-containing green tea polyphenols is associated with increased expression of sterol regulatory element-binding protein 2 and LDL receptor. Biochimica et Biophysica Acta 1682 1-10

Kuhn K and Lotz M (2001) Regulation of CD95 (Fas/APO-1)-induced apoptosis in human chondrocytes. Arthritis & Rheumatism 44 1644-1653

Kuhn K, Hashimoto S and Lotz M (2000) IL-1 beta protects human chondrocytes from CD95-induced apoptosis. Journal of Immunology 164 2233-2239

Kuhnel F, Zender L, Paul Y, Tietze MK, Trautwein C, Manns M and Kubicka S (2000) NFkB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis. Journal of Biological Chemistry 275 6421-6427

Kuhns DB, Priel DA and Gallin JI (2007) Induction of human monocyte interleukin (IL)-8 by fibrinogen through the Toll-like receptor pathway. Inflammation 30 178-188

Kuhtreiber WM, Hayashi T, Dale EA and Faustman DL (2003) Central role of defective apoptosis in autoimmunity. Journal of Molecular Endocrinology 31 373-399

Kuipers HF, Biesta PJ, Montagne LJ, van Haastert ES, van der Valk and van den Elsen PJ (2008)  CC chemokine receptor 5 (CCR5) gene promoter activation by the cyclic AMP response element binding (CREB) transcription factor. Blood in press

Kukan M (2004) Emerging roles of proteasomes in ischemia-reperfusion injury of organs. Journal of Physiology and Pharmacology 55 3-15

Kukreja P, Abdel-Mageed AB, Mondal D, Liu K and Agrawal KC (2005) Up-regulation of CXCR4 expression in PC-3 cells by stromal-derived factor-1alpha (CXCL12) increases endothelial adhesion and transendothelial migration: role of MEK/ERK signaling pathway-dependent NF-kB activation. Cancer Research 65 9891-9898

Kuldo JM, Ogawara KI, Werner N, Asgeirsdottir SA, Kamps JA, Kok RJ and Molema G (2005) Molecular pathways of endothelial cell activation for (targeted) pharmacological intervention of chronic inflammatory diseases. Current Vascular Pharmacology 3 11-39

Kuldo JM, Westra J, Asgeirsdottir SA, Kok RJ, Oosterhuis K, Rots MG, Schouten JP, Limburg PC and Molema G (2005) Differential effects of NF-kB and p38 MAPK inhibitors and combinations thereof on TNF{alpha} and IL-1b induced pro-inflammatory status of endothelial cells in vitro. American Journal of Physiology: Cell Physiology 289 C1229-C1239

Kulka M, Alexopoulou L, Flavell RA and Metcalfe DD (2004) Activation of mast cells by double-stranded RNA: Evidence for activation through Toll-like receptor 3. Journal of Allergy and Clinical Immunology 114 174-182

Kulms D and Schwarz T (2006) NF-kB and cytokines. Vitamins and Hormones 74C 283-300

Kumagai N, Ohno K, Tameshige R, Hoshijima M, Yogo K, Ishida N and Takeya T (2004) Induction of mouse c-src in RAW264 cells is dependent on AP-1 and NF-kB and important for progression to multinucleated cell formation. Biochemical and Biophysical Research Communications 325 758-768

Kumagai T, Matsukawa N, Kaneko Y, Kusumi Y, Mitsumata M and Uchida K (2004) A lipid peroxidation-derived inflammatory mediator: Identification of 4-hydroxy-2-nonenal as a potential inducer of cyclooxygenase-2 in macrophages. Journal of Biological Chemistry 279 48389-48396

Kumar A and Boriek AM (2003) Mechanical stress activates the nuclear factor-kB pathway in skeletal muscle fibers: a possible role in Duchenne muscular dystrophy. FASEB Journal 17 386-396

Kumar A, Dhawan S and Aggarwal BB (1998) Emodin (3-methyl-1,6,8-trihydroxyanthaquinone) inhibits TNF-induced NF-kB activation, IkB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells. Oncogene 17 913-918

Kumar A, Dhawan S, Hardegen NJ and Aggarawal BB (1998) Curcumin (Diferuloylmethane) inhibition of tumor necrosis factor (TNF)-mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion molecules and of Nuclear Factor-kB activation. Biochemical Pharmacology 55 775-783

Kumar A, Dhawan S, Mukhopadhyay A and Aggarwal BB (1999) Human immunodeficiency virus-1-tat induces matrix metalloproteinase-9 in monocytes through protein tyrosine phosphatase-mediated activation of nuclear transcription factor NF-kB. FEBS Letters 462 140-144

Kumar A, Haque J, Lacoste J, Hiscott J and Williams BRG (1994) Double-stranded RNA-dependent protein kinase activates transcription factor NF-kB by phosphorylating IkB. Proceedings of the National Academy of Sciences USA 91 6288-6292

Kumar A, Hawkins KS, Hannan MA and Ganz MB (2001) Activation of PKC-beta(I) in glomerular mesangial cells is associated with specific NF-kB subunit translocation. American Journal of Physiology: Renal Physiology 281 F613-F619

Kumar A, Jasmin A, Eby MT and Chaudhary PM (2001) Cytotoxicity of Tumor necrosis factor related apoptosis-inducing ligand towards Ewing’s sarcoma cell lines. Oncogene 20 1010-1014

Kumar A, Knox AJ and Boriek AB (2003) CCAAT/enhancer-binding protein and activator protein-1 transcription factors regulate the expression of interleukin-8 through the mitogen-activated protein kinase pathways in response to mechanical stretch. Journal of Biological Chemistry 278 18868-18876

Kumar A, Kumar A, Michael P, Brabant D, Parissenti AM, Ramana CV, Xu X and Parrillo JE (2005) Human serum from patients with septic shock activates transcription factor STAT1, IRF1 and NF-kB and induces apoptosis in human cardiac myocytes. Journal of Biological Chemistry 280 42619-42626

Kumar A, Lin Z, Senbanerjee S and Jain MK (2005) Tumor necrosis factor alpha-mediated reduction of KLF2 is due to inhibition of MEF2 by NF-kB and histone deacetylases. Molecular and Cellular Biology 25 5893-5903

Kumar A, Lnu S, Malya R, Barron D, Moore J, Corry DB and Boriek AM (2003) Mechanical stretch activates nuclear factor-kB, activator protein-1, and mitogen-activated protein kinases in lung parenchyma: implications in asthma. FASEB Journal 17 1800-1811

Kumar A, Malik F, Bhushan S, Sethi VK, Shahi AK, Kaur J, Taneja SC, Qazi GN and Singh J (2007) An essential oil and its major constituent isointermedeol induce apoptosis by increased expression of mitochondrial cytochrome c and apical death receptors in human leukaemia HL-60 cells. Chem Biol Interactions in press

Kumar A, Murphy R, Robinson P, Wei L and Boriek AM (2004) Cyclic mechanical strain inhibits skeletal myogenesis through activation of focal adhesion kinase, Rac-1 GTPase, and NF-kB transcription factor. FASEB Journal 18 1524-1535

Kumar A, Sinha RA, Tiwari M, Singh R, Koji T, Manhas N, Rastogi L, Pal L, Shrivastava A, Sahu RP and Godbole MM (2007) Hyperthyroidism induces apoptosis in rat liver through activation of death receptor-mediated pathways. Journal ofHepatology 46 888-898

Kumar A, Takada Y, Boriek AM and Aggarwal BB (2004) Nuclear factor-kB: its role in health and disease. Journal of Molecular Medicine 82 434-448

Kumar A, Tassopoulos AM, Li Q and Yu FS (2007) Staphylococcus aureus protein A induced inflammatory response in human corneal epithelial cells. Biochemical and Biophysical Research Communications 354 955-961

Kumar A, Upadhyay G, Modi DR and Singh MP (2007) The involvement of secondary signaling molecules in cytochrome P-450 1A1-mediated inducible nitric oxide synthase expression in benzo(a)pyrene-treated rat polymorphonuclear leukocytes. Life Sciences in press

Kumar A, Wu H, Collier-Hyams LS, Hansen JM, Li T, Yamaoah K, Pan ZQ, Jones DP and Neish AS (2007) Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species. EMBO Journal 26 4457-4466

Kumar A, Yang Y-L, Flati V, Der S, Kadereit S, Deb A, Haque J, Reis L, Weissmann C and Williams BRG (1997) Deficient cytokine signaling mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kB. EMBO Journal 16 406-416

Kumar A, Yin J, Zhang J and Yu FS (2007) Modulation of corneal epithelial innate immune response to pseudomonas infection by flagellin pretreatment. InvestigativeOphthalmology & Visual Science 48 4664-4670

Kumar A, Zhang J and Yu FS (2004) Innate immune response of corneal epithelial cells to Staphylococcus aureus infection: role of peptidoglycan in stimulating proinflammatory cytokine secretion. Investigative Ophthalmology and Visual Science 45 3513-3522

Kumar A, Zhang J and Yu FS (2006) Toll-like receptor 2-mediated expression of beta-defensin-2 in human corneal epithelial cells. Microbes and Infection 8 380-389

Kumar A, Zhang J and Yu FS (2006) Toll-like receptor 3 agonist poly(I:C)-induced antiviral response in human corneal epithelial cells. Immunology 117 11-21

Kumar B, Husain SA and Chandra B (2005) Constitutive activation of nuclear factor-kB: preferential homodimerization of p50 subunits in cervical carcinoma. Frontiers in Bioscience 10 1510-1519

Kumar B, Kumar A, Pandey BN, Hazra B and Mishra KP (2008) Increased cytotoxicity by the combination of radiation and diospyrin diethylether in fibrosarcoma in culture and in tumor. International Journal of Radiation Biology 84 429-440

Kumar D, Gokhale P, Broustas C, Chakravarty D, Ahmad I and Kasid U (2004) Expression of SCC-S2, an antiapoptotic molecule, correlates with enhanced proliferation and tumorigenicity of MDA-MB 435 cells. Oncogene 23 612-616

Kumar H, Kawai T, Kato H, Sato S, Takahashi K, Coban C, Yamamoto M, Uematsu S, Ishiii KJ, Takeuchi O and AKira S (2006) Essential role of IPS-1 in innate immune responses against RNA viruses. Journal of Experimental Medicine 203 1795-1803

Kumar KA, Rajgopal Y, Pillai U and Babu PP (2003) Activation of nuclear transcription factor-kB is associated with the induction of inhibitory kB kinase-beta and involves differential activation of protein kinase C and protein tyrosine kinases during fatal murine cerebral malaria. Neuroscience Letters 340 139-142

Kumar R, Singh PK, Sharma A, Prasad J, Sagar R, Singh S, Arora R and Sharma RK (2005) Podophyllum hexandrum extract provides radioprotection by modulating the expression of proteins associated with apoptosis. Biotechnology and Applied Biochemistry 42 81-92

Kumar S, Blake SM and Emery JG (2001) Intracellular signaling pathways as a target for the treatment of rheumatoid arthritis. Current Opinion in Pharmacology 1 307-313

Kumar S and Gélinas C (1993) IkBa-mediated inhibition of v-Rel DNA-binding requires direct interaction with the RxxRxRxxC Rel/kB DNA-binding motif. Proceedings of the National Academy of Sciences USA 90 8962-8966

Kumar S, Rabson AB and Gelinas C (1992) The RxxRxRxxC motif conserved in all Rel/kB proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoprotein. Molecular and Cellular Biology 12 3094-3106

Kumar S, Sharma A, Madan B, Singhal V and Ghosh B (2007) Isoliquiritigenin inhibits IkB kinase activity and ROS generation to block TNF-a induced expression of cell adhesion molecules on human endothelial cells. Biochemical Pharmacology 73 1602-1612

Kumar S, Singh BK, Pandey AK, Kumar A, Sharma SK, Raj HG, Prasad AK, Eycken EV, Parmar VS and Ghosh B (2007) A chromone analog inhibits TNF-alpha induced expression of cell adhesion molecules on human endothelial cells via blocking NF-kB activation.Bioorganic Medicinal Chemistry 15 2952-2962

Kumar S, Singhal V, Roshan R, Sharma A, Rembhotkar GW and Ghosh B (2007) Piperine inhibits TNF-a induced adhesion of neutrophils to endothelial monolayer through suppression of NF-kB and IkB kinase activation. European Journal of Pharmacology inpress

Kumar U, Chen J, Sapoznikhov V, Canteros G, White BH and Sidhu A (2005) Overexpression of inducible nitric oxide synthase in the kidney of the spontaneously hypertensive rat. Clinical and Experimental Hypertension 27 17-31

Kumar Mangalam A, Aggarwal A and Naik S (2002) Gold sodium thiomalate (GSTM) inhibits lipopolysaccharide stimulated tumor necrosis factor-alpha through ceramide pathway. Cellular Immunology 219 1-10

Kumar Mitra A and Krishna M (2004) In vivo modulation of signaling factors involved in cell survival. Journal of Radiation Research (Tokyo) 45 491-495

Kumar-Sinha C, Varambally S, Sreekumar A and Chinnaiyan AM (2002) Molecular cross-talk between the TRAIL and interferon signaling pathways. Journal of Biological Chemistry 277 575-585

Kumamoto H and Ooya K (2005) Expression of tumor necrosis factor alpha, TNF-related apoptosis-inducing ligand, and their associated molecules in ameloblastomas. Journal of Oral Pathology and Medicine 34 287-294

Kumwenda ZL, Wong CB, Johnson JA, Gosnell JE, Welch WJ and Harris HW (2002) Chylomicron-bound endotoxin selectively inhibits NF-kB activation in rat hepatocytes. Shock 18 182-188

Kun JF (2003) Regulation of nitrogen monoxide production in human malaria. Redox Reports 8 289-291

Kunath K, von Harpe A, Petersen H, Fischer D, Voigt K, Kissel T and Bickel U (2002)The structure of PEG-modified poly(ethylene imines) influences biodistribution and pharmacokinetics of their complexes with NF-kB decoy in mice. Pharmaceutical Research 19 810-817

Kundu JK, Mossanda KS, Na HK and Surh YJ (2005) Inhibitory effects of the extracts of Sutherlandia frutescens (L.) R. Br. and Harpagophytum procumbens DC. on phorbol ester-induced COX-2 expression in mouse skin: AP-1 and CREB as potential upstream targets. Cancer Letters 218 21-31

Kundu JK, Shin YK and Surh YJ (2006) Resveratrol inhibits phorbol ester-induced expression of COX-2 and activation of NF-kB in mouse skin by blocking IkB kinase activity. Carcinogenesis 27 1465-1474

Kundu JK, Shin YK and Surh YJ (2006) Resveratrol modulates phorbol ester-induced pro-inflammatory signal transduction pathways in mouse skin in vivo: NF-kB and AP-1 as prime targets. Biochemical Pharmacology in press

Kundu JK and Surh YJ (2004) Molecular basis of chemoprevention by resveratrol: NF-kB and AP-1 as potential targets. Mutation Research 555 65-80

Kundu JK and Surh YJ (2005) Breaking the relay in deregulated cellular signal transduction as a rationale for chemoprevention with anti-inflammatory phytochemicals. Mutation Research 591 123-146

Kundu JK and Surh YJ (2007) Epigallocatechin gallate inhibits phorbol ester-induced activation of NF-kB and CREB in mouse skin: role of p38 MAPK. Annals of the New York Academy of Sciences 1095 504-512

Kundu M, Ansari SA, Chepenik LG, Pomerantz RJ, Khalili K, Rappaport J and Amini S (1999) HIV-1 regulatory protein tat induces RNA binding proteins in central nervous system cells that associate with the viral trans-acting-response regulatory motif. Journal of Human Virology 2 72-80

Kundu M, Guermah M, Roeder RG, Amini S and Khalili K (1997) Interaction between cell cycle regulator, E2F-1, and NF-kB mediates repression of HIV-1 gene transcription. Journal of Biological Chemistry 272 29468-29526

Kung CP and Raab-Traub N (2008) Epstein-Barr virus latent membrane protein 1 induces expression of the epidermal growth factor receptor through effects on Bcl-3 and STAT3. Journal of Virology 82 5486-5493

Kunigal S, Lakka SS, Joseph P, Estes N and Rao JS (2008) Matrix metalloproteinase-9 inhibition down-regulates radiation-induced nuclear factor-kB activity leading to apoptosis in breast tumors. Clinical Cancer Research 14 3617-3626

Kunisawa J, Gohda M, Kurashima Y, Ishikawa I, Higuchi M and Kyono H (2008) Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NFkB-inducing kinase in stromal cells. Blood 111 4646-4652

Kunnumakkara AB, Diagaradjane P, Guha S, Deonukhkar A, Shentu S, Aggarwal BB and Krishnan S (2008) Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kB-regulated gene products. Clinical Cancer Research 14 2128-2136

Kunnumakkara AB, Guha S, Krishnan S, Diagaradjane P, Gelovani J and Aggarwal BB (2007) Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kB-regulated gene products. Cancer Research 673853-3861

Kunnumakkara AB, Nair AS, Ahn KS, Pandey MK, Yi Z, Liu M and Aggarwal BB (2007)Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1 mediated NF-kB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis. Bloodin press

Kuno K, Ishikawa Y, Ernst MK, Ogata M, Rice NR, Mukaida N and Matsushima K (1995) Identification of an IkBa-associated kinase in a human monocytic cell line and determination of its phosphorylation sites on IkBa. Journal of Biological Chemistry 270 27914-27919

Kuno K, Sukegawa K, Ishikawa Y, Orii T and Matsushima K (1994) Acid sphingomyelinase is not essential for IL-1 and TNF receptor signaling pathway leading to NFkB activation. International Immunology 6 1269-1272

Kunsch C and Rosen CA (1993) NF-kB subunit-specific regulation of the interleukin-8 promoter. Molecular and Cellular Biology 13 6137-6146

Kunsch C, Lang RK, Rosen CA and Shannon MF (1994) Synergistic transcriptional activation of the IL-8 gene by NF-kB p65 (RelA) and NF-IL-6. Journal of Immunology 153 153-164

Kunsch C, Luchoomun J, Chen X, Dodd G, Karu K, Meng C, Marino E, Olliff L, Piper JD, Qiu FH, Sikorski J, Somers P, Suen KL, Thomas S, Whalen A, Wasserman M and Sundell C (2005) AGIX-4207, a novel antioxidant and anti-inflammatory compound: I. Cellular and biochemical characterization of antioxidant activity and inhibition of redox-sensitive inflammatory gene expression. Journal of Pharmacology and Experimental Therapeutics 313 492-501

Kunsch C, Luchoomun J, Grey JY, Olliff LK, Saint LB, Arrendale RF, Wasserman MA, Saxena U and Medford RM (2004) Selective inhibition of endothelial and monocyte redox-sensitive genes by AGI-1067: a novel, antioxidant and anti-inflammatory agent. Journal of Pharmacology and Experimental Therapeutics 308 820-829

Kunsch C, Ruben SM and Rosen CA (1992) Selection of optimal kB/Rel DNA-binding motifs: interaction of both subunits of NF-kB with DNA is required for transcriptional activation. Molecular and Cellular Biology 12 4412-4421

Kunter Y, Daniel S, Arvelo MB, Choi J, Shukri T, Patel VI, Longo CR, Scali ST, Shrikhande G, Rocha E, Czismadia E, Mottley C, Grey ST, Floege J and Ferran C (2005) Combined expression of A1 and A20 achieves optimal protection of renal proximal tubular epithelial cells. Kidney International 68 1520-1532

Kuntzen C, Zazzeroni F, Pham CG, Papa S, Bubici C, Knabb JR and Franzoso G (2007) A method for isolating prosurvival targets of NF-kB/Rel transcription factors. Methods in Molecular Biology 399 99-124

Kunugiza Y, Tomita T, Tomita N, Morishita R and Yoshikawa H (2006) Inhibitory effect of ribbon-type NF-kB decoy oligodeoxynucleotides on osteoclast induction and activity in vitro and in vivo. Arthritis Research & Therapy 8 R103

Kunz A, Abe T, Hochrainer K, Shimamura M, Anrather J, Racchumi G, Zhou P and Iadecola C (2008) Nuclear factor-kB activation and postischemic inflammation are suppressed in CD36-null mice after middle cerebral artery occlusion. Journal of Neuroscience 28 1649-1658

Kunz D, Walker G, Eberhardt W, Nitsch D and Pfeilschifter J (1995) Interleukin 1b-induced expression of nitric oxide synthease in rat renal mesangial cells is suppressed by cyclosporin A. Biochemical and Biophysical Research Communications 216 438-446

Kunz M, Blo G, Gillitzer R, Gross G, Goebeler M, Rapp UR and Ludwig S (2002) Hypoxia/reoxygenation-induction of monocyte chemoattractant protein -1 in melanoma cells. Involvement of NF-kB and SP-1 transcription factors and mitogen activated protein kinase pathways. Biochemical Journal 366 299-306

Kunz M, Bloss G, Gillitzer R, Gross G, Goebeler M, Rapp UR and Ludwig S (2002) Hypoxia/reoxygenation-induction of monocyte chemoattractant protein -1 in melanoma cells. Involvement of NF-kB and SP-1 transcription factors and mitogen activated protein kinase pathways. Biochemical Journal 366 299-306

Kunz M, Hartmann A, Flory E, Toksoy A, Koczan D, Thiesen HJ, Mukaida N, Neumann M, Rapp UR, Brocker EB and Gillitzer R (1999) Anoxia-induced up-regulation of interleukin-8 in human malignant melanoma. A potential mechanism for high tumor aggressiveness. American Journal of Pathology 155 753-763

Kuo AH, Stoica GE, Riegel AT and Wellstein A (2007) Recruitment of insulin receptor substrate-1 and activation of NF-kB essential for midkine growth signaling through anaplastic lymphoma kinase. Oncogene 26 859-869

Kuo CC, Lin WT, Liang CM and Liang SM (2006) Class I and III phosphatidylinositol 3′-kinase play distinct roles in TLR signaling pathway. Journal of Immunology 176 5943-5949

Kuo CL, Ho FM, Chang MY, Prakash E and Lin WW (2007) Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 5-aminoimidazole-4-carboxamide riboside is independent of AMP-activated protein kinase. Journal of Cellular Biochemistry in press

Kuo CT and Leiden JM (1999) Transcriptional regulation of T lymphocyte development and function. Annual Review of Immunology 17 149-187

Kuo HP, Wang CH, Huang KS, Lin HC, Yu CT, Liu CY and Lu LC (2000) Nitric oxide modulates interleukin-1beta and tumor necrosis factor-alpha synthesis by alveolar macrophages in pulmonary tuberculosis. American Journal of Respiratory Critical Care Medicine 161 192-199

Kuo MC, Weng CY, Ha CL and Wu MJ (2005) Ganoderma lucidum mycelia enhance innate immunity by activating NF-kB. Journal of Ethnopharmacology 103 217-222

Kuo MT, Liu Z, Wei Y, Lin-Lee YC, Tatebe S, Mills GB and Unate H (2002) Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kB signaling. Oncogene 21 1945-1954

Kuo PL, Hsu YL, Lin TC, Tzeng WS, Chen YY and Lin CC (2006) Rugosin E, an ellagitannin, inhibits MDA-MB-231 human breast cancer cell proliferation and induces apoptosis by inhibiting nuclear factor-kB signaling pathway. Cancer Letters 2248 280-291

Kuo SH, Chen LT, Yeh KH, Wu MS, Hsu HC, Yeh PY, Mao TL, Chen CL, Doong SL, Lin JT and Cheng AL (2004) Nuclear expression of BCL10 or nuclear factor kB predicts Helicobacter pylori-independent status of early-stage, high-grade gastric mucosa-associated lymphoid tissue lymphomas. Journal of Clinical Oncology 22 3491-3497

Kuo SH, Yeh PY, Chen LT, Wu MS, Lin CW, Yeh KH, Tzeng YS, Chen JY, Hsu PN, Lin JT and Cheng AL (2008) Overexpression of B-cell activating factor of TNF family (BAFF) is associated with Helicobacter pylori-independent growth of gastric diffuse large B-cell lymphoma with histologic evidence of MALT lymphoma. Blood in press

Kuo YR, Wang FS, Jeng SF, Lutz BS, Huang HC and Yang KD (2004) Nitrosoglutathione promotes flap survival via suppression of reperfusion injury-induced superoxide and inducible nitric oxide synthase induction. Journal of Trauma 57 1025-1031

Kupatt C, Habazettl H, Goedecke A, Wolf DA, Zahler S, Boekstegers P, Kelly RA and Becker BF (1999) Tumor necrosis factor-alpha contributes to ischemia- and reperfusion-induced endothelial activation in isolated hearts. Circulation Research 84 392-400

Kupatt C, Hinkel R, Vachenauer R, Horstkotte J, Raake P, Sandner T, Kreuzpointner R, Muller F, Dimmeler S, Feron O and Boekstegers P (2003) VEGF165 transfection decreases postischemic NF-kB-dependent myocardial reperfusion injury in vivo: role of eNOS phosphorylation. FASEB Journal 17 705-707

Kupatt C, Wichels R, Deiss M, Molnar A, Lebherz C, Raake P, von Degenfeld G, Hahnel D and Boekstegers P (2002) Retroinfusion of NFkB decoy oligonucleotide extends cardioprotection achieved by CD18 inhibition in a preclinical study of myocardial ischemia and retroinfusion in pigs. Gene Therapy 9 518-526

Kupfer R, Lang J, Williams-Skipp C, Nelson M, Bellgrau D and Schienman RI (2006) Loss of a gimap/ian gene leads to activation of NF-kB through a MAPK-dependent pathway. Molecular Immunology 44 479-487

Kupfer R and Scheinman RI (2002) Measurement of IKK activity in primary rat T cells: rapid activation and inactivation. Journal of Immunological Methods 266 155-164

Kuphal S, Poser I, Jobin C, Hellerbrand C and Bosserhoff AK (2004) Loss of E-cadherin leads to upregulation of NFkB activity in malignant melanoma. Oncogene 23 8509-8519

Kuprash DV, Rice NR and Nedospasov SA (1995) Homodimer of p50 (NFkB1) does not introduce a substantial directed bend into DNA according to three different experimental assays. Nucleic Acids Research 23 427-433

Kuprash DV, Udalova IA, Turetskaya RL, Kwiatkowski D, Rice NR and Nedospasov SA (1999) Similarities and differences between human and murine TNF promoters in their response to lipopolysaccharide. Journal of Immunology 162 4045-4052

Kuprash DV, Udalova TA, Turetskaya RL, Rice NR and Nedospasov SA (1995) Conserved kB element located downstream of the tumor necrosis factor a gene: distinct NF-kB binding pattern and enhancer activity in LPS activated murine macrophages. Oncogene 11 97-106

Kuramoto T, Nishikawa M, Thanaketpaisarn O, Okabe T, Yamashita F and Hashida M (2005) Use of lipoplex-induced nuclear factor-kB activation to enhance transgene expression by lipoplex in mouse lung. Journal of Gene Medicine 8 53-62

Kurata S and Yamamoto N (1999) Glucocorticoid can reduce the transcriptional activation of HIV-1 promoter through the reduction of active NF-kB. Journal of Cellular Biochemistry 76 13-19

Kurata S, Wakabayashi T, Ito Y, Miwa N, Ueno R, Marunouchi T and Kurata N (1993) Human neuroblastoma cells produce the NF-kB-like HIV-1 transcription activator during differentiation. FEBS Letters 321 201-204

Kurban S, Akpinar Z and Mehmetoglu I (2008) Receptor activator of nuclear factor kB ligand (RANKL) and osteoprotegerin levels in multiple sclerosis. Multiple Sclerosis in press

Kurbanov BM, Fecker LF, Geilen CC, Sterry W and Eberle J (2007) Resistance of melanoma cells to TRAIL does not result from upregulation of antiapoptotic proteins by NF-kB but is related to downregulation of initiator caspases and DR4. Oncogene in press

Kurebayashi S, Xu X, Ishii S, Shiraishi M, Kouhara H and Kasayama S (2005) A novel thiazolidinedione MCC-555 down-regulates tumor necrosis factor-alpha-induced expression of vascular cell adhesion molecule-1 in vascular endothelial cells.Atherosclerosis 182 71-77

Kurexi Y, Huang GH, Long M, He J, Nasier M, Xia YP and Hamulati W (2007) Construction of NF-kB siRNA expression vector [Article in Chinese]. Zhong Nan Da Xue Xue Bao Yi Xue Ban 32 765-770

Kurihara N, Hiruma Y, Zhou H, Subler MA, Dempster DW, Singer FR, Reddy SV, Gruber HE, Windle JJ and Roodman GD (2007) Mutation of the sequestosome 1 (p62) gene increases osteoclastogenesis but does not induce Paget disease. Journal of ClinicalInvestigation 117 133-142

Kurihara N, Reddy SV, Menaa C, Anderson D and Roodman GD (2000) Osteoclasts expressing the measles virus nucleocapsid gene display a pagetic phenotype. Journal of Clinical Investigation 105 607-614

Kurland JF and  Meyn RE (2001) Protease inhibitors restore radiation-induced apoptosis to Bcl-2-expressing lymphoma cells. International Journal of Cancer 20 327-333

Kurland JF, Kodym R, Story MD, Spurgers KB, McDonnell TJ and Meyn RE (2001) NF-kB1 (p50) homodimers contribute to transcription of the bcl-2 oncogene. Journal of Biological Chemistry 276 45380-4538

Kurland JF, Voehringer DW and Meyn RE (2003) The MEK/ERK pathway acts upstream of NF-kB1 (p50) homodimer activity and Bcl-2 expression in a murine B-Cell lymphoma cell line: MEK inhibition restores radiation-induced apoptosis. Journal of Biological Chemistry 278 32465-32470

Kuroda K, Horiguchi Y, Nakashima J, Kikuchi E, Kanao K, Miyajima A, Ohigashi T, Umezawa K and Murai M (2005) Prevention of cancer cachexia by a novel nuclear factor kB inhibitor in prostate cancer. Clincal Cancer Research 11 5590-5594

Kuroda Y, Hisatsune C, Nakamura T, Matsuo K and Mikoshiba K (2008) Osteoblasts induce Ca2+ oscillation-independent NFATc1 activation during osteoclastogenesis. Proceedings of the National Academy of Sciences USA in press

Kuroishi T, Endo Y, Muramoto K and Sugarawa S (2008) Biotin deficiency up-regulates TNF-a production in murine macrophages. Journal of Leukocyte Biology in press

Kurokawa M, Brown J, Kagawa Y and Shiraki K (2003) Cytokine-regulatory activity and therapeutic efficacy of cinnamyl derivatives in endotoxin shock. European Journal of Pharmacology 474 283-293

Kurokawa M, Ghosh SK, Ramos JC, Mian AM, Toomey NL, Cabral L, Whitby D, Barber GN, Dittmer DP and Harrington Jr WJ (2005) Azidothymidine inhibits NF-kB and induces Epstein-Barr virus gene expression in Burkitt lymphoma. Blood 106 235-240

Kuroki H, Morisaki T, Matsumoto K, Onishi H, Baba E, Tanaka M and Katano M (2003) Streptococcal preparation OK-432: a new maturation factor of monocyte-derived dendritic cells for clinical use. Cancer Immunology and Immunotherapy 52 561-568

Kurokouchi K, Jacobs CR and Donahue HJ (2001) Oscillating fluid flow inhibits TNF-a-induced NF-kB activation via an IkB kinase pathway in osteoblast-like UMR106 cells. Journal of Biological Chemistry 276 13499-134504

Kurozumi R and Kojima S (2005) Increase of intracellular glutathione by low-level NO mediated by transcription factor NF-kB in RAW 264.7 cells. Biochimica et Biophysica Acta 1744 58-67

Kurpius D, Wilson N, Fuller L, Hoffman A and Dailey ME (2006) Early activation, motility, and homing of neonatal microglia to injured neurons does not require protein synthesis. Glia 54 58-70

Kurt RA, Urba WJ, Smith JW and Schoof DD (1998) Peripheral T lymphocytes from women with breast cancer exhibit abnormal protein expression of several signaling molecules. International Journal of Cancer 78 16-20

Kurtovic J and Segal I (2004) Recent advances in biological therapy for inflammatory bowel disease. Tropical Gastroenterology 25 9-14

Kury P, Schroeter M and Jander S (2004) Transcriptional response to circumscribed cortical brain ischemia: spatiotemporal patterns in ischemic vs. remote non-ischemic cortex. European Journal of Neuroscience 19 1708-1720

Kurzrock R, Talpaz M, Li L and Estrov Z (2006) Distinct biological impact of dephosphorylation vs. downregulation of p210Bcr-Abl: Implications for imatinib mesylate response and resistance. Leukemia and Lymphoma 47 1651-1664

Kusaka M, Yamada K, Kuroyanagi Y, Terauchi A, Kowa H, Kurahashi H and Hoshinaga K (2005) Gene expression profile in rat renal isografts from brain dead donors.Transplantation Proceedings 37 364-366

Kusagawa S, Imamura Y, Yasuoka A, Hoshino H, Oka S and Takebe Y (2003) Identification of HIN type 2 subtype B transmission in East Africa. AIDS Research & Human Retroviruses 19 1045-1049

Kushner DB and Ricciardi RP (1999) Reduced phosphorylation of p50 is responsible for diminished NF-kB binding to the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells. Molecular and Cellular Biology 19 2169-2179

Kushner DB, Pereira DS, Liu X, Graham FL and Riciardi RP (1996) The first exon of Ad12 E1A excluding the transactivation domain mediates differential binding of COUP-TF and NF-kB to the MHC class I enhancer in transformed cells. Oncogene 12 143-151

Kusmic C, Basta G, Lazzerini G, Vesentini N and Barsacchi R (2004) The effect of ginkgo biloba in isolated ischemic/reperfused rat heart: a link between vitamin E preservation and prostaglandin biosynthesis. Journal of Cardiovascular Pharmacology44 356-362

Kusminski CM, da Silva NF, Creely SJ, Fisher FM, Harte AL, Baker AR, Kumar S and McTernan PG (2007) The in vitro effects of resistin on the innate immune signaling pathway in isolated human subcutaneous adipocytes. Journal of Clinical Endocrinology and Metabolism 92 270-276

Kustermans G, El Benna J, Piette J and Legrand-Poels S (2004) Perturbation of actin dynamics induces NF-kB activation in myelomonocytic cells via a NADPH oxidase-dependent pathway. Biochemical Journal 387 531-540

Kustermans G, Piette J and Legrand-Poels S (2008) Actin-targeting natural compounds as tools to study the role of actin cytoskeleton in signal transduction. Biochemical Pharmacology in press

Kusomoto H, Haraguchi M, Nozuka Y, Oda Y, Tsuneyoshi M and Iguchi H (2006) Characteristic features of disseminated carcinomatosis of the bone marrow due to gastric cancer: The pathogenesis of bone destruction. Oncology Reports 16 735-740

Kusumoto Y, Hirano H, Saitoh K, Yamada S, Takedachi M, Nozaki T, Ozawa Y, Nakahira Y, Saho T, Ogo H, Shimabukuro Y, Okada H and Murakami S (2004) Human gingival epithelial cells produce chemotactic factors interleukin-8 and monocyte chemoattractant protein-1 after stimulation with Porphyromonas gingivalis via toll-like receptor 2. Journal of Periodontology 75 370-379

Kutlu B, Darville MI, Cardozo AK and Eizirik DL (2003) Molecular regulation of monocyte chemoattractant protein-1 expression in pancreatic beta-cells. Diabetes 52 348-355

Kutlu B, Naamane N, Berthou L and Eizirik DL (2004) New approaches for in silico identification of cytokine-modified beta cell gene networks. Annals of the New York Academy of Sciences 1037 41-58

Kutuk O and Basaga H (2003) Inflammation meets oxidation: NF-kB as a mediator of initial lesion development in atherosclerosis. Trends in Molecular Medicine 9 549-557

Kutuk O and Basaga H (2003) Aspirin prevents apoptosis and NF-kB activation induced by H2O2 in Hela cells. Free Radical Research 37 1267-1276

Kutuk O and Basaga H (2004) Aspirin inhibits TNFalpha- and IL-1-induced NF-kB activation and sensitizes HeLa cells to apoptosis. Cytokine 25 229-237

Kutz H, Reisbach G, Schultheiss U and Kieser A (2007) The c-Jun N-terminal kinase pathway is critical for cell transformation by the latent membrane protein 1 of Epstein-Barr virus. Virology in press

Kuwabara N, Tamada S, Iwai T, Teramoto K, Kaneda N, Yukimura T, Nakatani T and Miura K (2006) Attenuation of renal fibrosis by curcumin in rat obstructive nephropathy.Urology 67 440-446

Kuwahara I, Lillehoj EP, Lu W, Singh IS, Isohama Y, Miyata T and Kim KC (2006) Neutrophil elastase induces IL-8 gene transcription and protein release through p38/NF-kB activation via EGFR transactivation in a lung epithelial cell line.American Journal of Physiology: Lung Cell and Molecular Physiology 291 L407-L416

Kuwata H, Matsumoto M Atarashi K, Morishita H, Hirotoni T, Koga R and Takeda K (2006) IkBNS inhibits induction of a subset of Toll-like receptor-dependent genes and limits inflammation. Immunity 24 41-51

Kuwata H, Watanabe Y, Miyoshi H, Yamamoto M, Kaisho T, Takeda K and Akira S (2003) IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-a production in macrophages. Blood 102 4123-4129

Kuwayama Y, Suzuki T, Moriuchi S, Glorioso JC and Bessho M (2005) IkB-mediated apoptotic gene therapy against acute myelogenous leukemia using replication-defective HSV-1 vector expressing tk and mutant IkBa. Cell Mol Biol (Noisy-le-grand)51 77-86

Kuzuhara T, Suganuma M, Kurusu M and Fujikai H (2007) Helicobacter pylori-secreting protein Tipalpha is a potent inducer of chemokine gene expressions in stomach cancer cells. Journal of Cancer Research and Clinical Oncology 133 287-296

Kuzuhara T, Suganuma M, Oka K and Fujiki H (2007) DNA-binding activity of TNF-a inducing protein from Helicobacter pylori.
Biochemical and Biophysical Research Communications in press

Kwak EL, Larochelle DA, Beaumont C, Torti SV and Torti FM (2005) Role for NF-kB in the regulation of ferritin H by tumor necrosis factor-a. Journal of Biological Chemistry 270 15285-15293

Kwak HB, Jin HM, Ha H, Kang MJ, Lee SB, Kim HH and Lee ZH (2005) Tumor necrosis factor-alpha induces differentiation of human peripheral blood mononuclear cells into osteoclasts through the induction of p21(WAF1/Cip1). Biochemical and Biophysical Research Communications 330 1080-1086

Kwak HB, Lee SW, Jin HM, Ha H, Lee SH, Takeshita S, Tanaka S, Kim HM, Kim HH and Lee ZH (2005) Monokine induced by interferon-gamma is induced by receptor activator of nuclear factor kB ligand and involved in osteoclast adhesion and migration. Blood 105 2963-2969

Kwak HB, Lee SW, Lee DG, Hahm KS, Kim KK, Kim HH and Lee ZH (2003) A hybrid peptide derived from cecropin-A and magainin-2 inhibits osteoclast differentiation. Life Sciences 73 993-1005

Kwak HB, Lee SW, Li YJ, Kim YA, Han SY, Jhon GJ, Kim HH and Lee ZH (2004) Inhibition of osteoclast differentiation and bone resorption by a novel lysophosphatidylcholine derivative, SCOH. Biochemical Pharmacology 67 1239-1248

Kwak HB, Yang D, Ha H, Lee JH, Kim HN, Woo ER, Lee S, Kim HH and Lee ZH (2006) Tanshinone IIA inhibits osteoclast differentiation through down-regulation of c-Fos and NFATc1. Experimental and Molecular Medicine 38 256-264

Kwak HJ, Song JS, Heo JY, Yang SD, Nam JY and Cheon HG (2005) Roflumilast inhibits lipopolysaccharide-induced inflammatory mediators via suppression of NF-kB, P38 MAP kinase and JNK activation. Journal of Pharmacology and Experimental Therapeutics 315 1188-1195

Kwak JH, Kim BH, Jung JK, Kim Y, Cho J and Lee H (2007) Structure-activity relationships of 6-hydroxy-7-methoxychroman-2-carboxylic acid N-(substituted)phenylamides as inhibitors of nuclear factor-kappaB activation. Archives of Pharmacal Research 30 1210-1215

Kwak JH, Won SW, Kim TJ, Roh E, Kang HY, Lee HW, Jung JK, Hwang BY, Kim Y, Cho J and Lee H (2008) Synthesis of chroman-2-carboxylic acid N-(substituted)phenylamides and their inhibitory effect of nuclear factor-kB (NF-kB) activation. Archives of Pharmacal Research 31 133-141

Kwak SH, Wang XQ, He Q, Fang WF, Mitra S, Bdeir K, Ploplis VA, Xu Z, Kdell S, Cines D and Abraham E (2006) Plasminogen activator inhibitor-1 potentiates LPS-induced neutrophil activation through a JNK-mediated pathway. Thrombosis and Haemostosis 95 829-835

Kwak YT, Guo J, Shen J and Gaynor RB (2000) Analysis of domains in the IKKa and IKKb proteins that regulate their kinase activity. Journal of Biological Chemistry 275 14752-14759

Kwak Y-T, Li R, Becerra CR, Tripathy D, Frenkel EP and Verma UN (2005) IkB kinase alpha regulates subcellular distribution and turnover of cyclin D1 by phosphorylation. Journal of Biological Chemistry 280 33945-33952 (Correction JBC 280 38888)

Kwakkel J, Wiersinga WM and Boelen A (2006) Differential involvement of nuclear factor-kB and activator protein-1 pathways in the interleukin-1beta-mediated decrease of deiodinase type 1 and thyroid hormone receptor beta1 mRNA. Journal ofEndocrinology 189 37-44

Kwakkel J, Wiersinga WM and Boelen A (2007) Interleukin-1beta modulates endogenous thyroid hormone receptor alpha gene transcription in liver cells. Journal ofEndocrinology 194 257-265

Kwan Tat S, Pelletier JP, Lajeunesse D, Fahmi H, Lavigne M and Martel-Pelletier J (2008) The differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kB ligand (RANKL) in human osteoarthritic subchondral bone osteoblasts is an indicator of the metabolic state of these disease cells. Clinical and Experimental Rheumatology 26 295-304

Kweon SM, Wang B, Rixter D, Lim JH, Koga T, Ishinaga H, Chen LF, Jono H, Xu H and Li JD (2006) Synergistic activation of NF-kB by nontypeable H. influenzae and S. pneumoniae is mediated by CK2, IKKb-IkBa, and p38 MAPK. Biochemical and BiophysicalResearch Communications 351 368-375

Kwiecinska P, Roszkiewicz B, Lokociejewska M and Orzechowski A (2005) Elevated expression of NF-kB and Bcl-2 proteins in C2C12 myocytes during myogenesis is affected by PD98059, LY294002 and SB203580. Cell Biology International 29 319-331

Kwok BHB, Koh B, Ndubuisi MI, Elofsson M and Crews CM (2001) The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkB kinase. Chemistry and Biology 8 759-766

Kwon AH and Qiu ZX (2007) Neutrophil elastase inhibitor prevents endotoxin-induced liver injury following experimental partial hepatectomy. British Journal of Surgery 94 609-619

Kwon AH, Qiu Z, Tsuji K, Miyaso T and Okumura T (2007) Fibronectin prevents endotoxin shock after partial hepatectomy in rats via inhibition of nuclear factor-kB and apoptosis. Experimental Biology and Medicine (Maywood) 232 895-903

Kwon BC, Sohn MH, Kim KW, Kim ES, Kim KE and Shin MH (2007) House dust mite induces expression of intercellular adhesion molecule-1 in EoL-1 human eosinophilic leukemic cells. Journal of Korean Medical Science 22 815-819

Kwon D, Fuller AC, Palma JP, Choi IH and Kim BS (2004) Induction of chemokines in human astrocytes by picornavirus infection requires activation of both AP-1 and NF-kB. Glia 45 287-296

Kwon H, Ogle L, Benitez B, Bohuslav J, Montano M, Felsher DW and Greene WC (2005) Lethal cutaneous disease in transgenic mice conditionally expressing HTLV-I tax. Journal of Biological Chemistry 280 35713-35722

Kwon HJ, Breese EH, Vig-Varga E, Luo Y, Lee Y, Goebl MG and Harrington MA (2004) Tumor necrosis factor alpha induction of NF-kB requires the novel coactivator SIMPL. Molecular and Cellular Biology 24 9317-9326

Kwon HJ and Kim DS (2003) Regulation of macrophage inflammatory protein-2 gene expression in response to oligodeoxynucleotide containing CpG motifs in RAW 264.7 cells. Biochemical and Biophysical Research Communications 308 608-613

Kwon HJ, Lee KW, Ho Yu S, Ho Han J and Kim DS (2003) NF-kB-dependent regulation of tumor necrosis factor-alpha gene expression by CpG-oligodeoxynucleotides. Biochemical and Biophysical Research Communications 311 129-138

Kwon HM, Choi YJ, Choi JS, Kang SW, Bae JY, Kang IJ, Jun JG, Lee SS, Lim SS and Kang YH (2007) Blockade of cytokine-induced endothelial cell adhesion molecule expression by licorice isoliquiritigenin through NF-kB signal disruption.
Experimental Biology and Medicine (Maywood) 232 235-245

Kwon HS, Brent M, Getachew R, Jayakumar P, Chen LF, Schnolzer M, McBruney MW, Marmorstein F, Greene WC and Ott M (2008) Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation. Cell Host Microbe 3 158-167

Kwon J, Pelletier N, DeLuca C, Genin P, Cisternas S, Lin R, Wainberg MA and Hiscott J (1998) Inducible expression of IkBa repressor mutants interferes with NF-kB activity and HIV-1 replication in Jurkat T Cells. Journal of Biological Chemistry 273 7431-7440

Kwon JA and Rho HM (2002) Hepatitis B viral core protein activates the hepatitis B viral enhancer II/pregenomic promoter through the nuclear factor kB binding site. Biochem Cell Biol 80 445-455

Kwon JH, Keates S, Simeonidis S, Grall F, Libermann TA and Keates AC (2003) ESE-1, an enterocyte-specific Ets transcription factor, regulates MIP-3alpha gene expression in Caco-2 human colonic epithelial cells. Journal of Biological Chemistry 278 875-884

Kwon KB, Kim EK, Jeong ES, Lee YH, Lee YR, Park JW, Ryu DG and Park BH (2006) Cortex cinnamomi extract prevents streptozotocin- and cytokine-induced beta-cell damage by inhibiting NF-kB. World Journal of Gastroenterology 12 4331-4337

Kwon KB, Kim JH, Lee YR, Lee HY, Jeong YJ, Rho HW, Ryu do G, Park JW and Park BH (2003) Amomum xanthoides extract prevents cytokine-induced cell death of RINm5F cells through the inhibition of nitric oxide formation. Life Science 73 181-191

Kwon KB, Kim EK, Lim JG, Shin BC, Song YS, Seo EA, Ahn KY, Song BK and Ryu DG (2004) Sophorae radix extract inhibits high glucose-induced vascular cell adhesion molecule-1 up-regulation on endothelial cell line. Clinica Chimica Acta 348 79-86

Kwon KB, Ryu DG, Shin MK, Shin BC, Hwang WJ, Lee YR, Park JW and Park BH (2003) Fructus Benincasae Recens extract prevents cytokine-induced nitric oxide formation and cytotoxicity of RINm5F cells. Immunopharmacology and Immunotoxicology 25 615-625

Kwon KH, Barve A, Yu S, Huang MT and Kong AN (2007) Cancer chemoprevention by phytochemicals: potential molecular targets, biomarkers and animal models. Acta Pharmacologica Sinica 28 1409-1421

Kwon KS and Chae HJ (2003) Sodium salicylate inhibits expression of COX-2 through suppression of ERK and subsequent NF-kB activation in rat ventricular cardiomyocytes. Archives of Pharmacology Research 26 545-553

Kwon O, Kim KA, He L, Jung M, Ahn JS and Kim BY (2007) Complex formation of p65/RelA with nuclear Akt1 for enhanced transcriptional activation of NF-kB. Biochemical and Biophysical Research Communications in press

Kwon O, Kim KA, He L, Kim SO, Kim MS, Cha EY, Yoon BD, Sok DE, Jung M, Ahn JS and Kim BY (2008) Ionizing radiation can induce GSK-3beta phosphorylation and NF-kB transcriptional transactivation in ATM-deficient fibroblasts. Cellular Signaling in press

Kwon O, Kim  KA, Kim SO, Ha R, Oh WK, Kim MS, Kim HS, Kim KD, Kim JW, Jung M, Kim CH, Ahn JS and Kim BY (2006) NF-kB inhibition increases chemosensitivity to trichostatin A-induced cell death of Ki-Ras-transformed human prostate epithelial cells. Carcinogenesis 27 2258-2268

Kwon O, Lee E, Moon TC, Jung H, Lin CX, Nam KS, Baek SH, Min HK and Chang HW (2002) Expression of cyclooxygenase-2 and pro-inflammatory cytokines induced by 2,2′,4,4′,5,5′-hexachlorobiphenyl (PCB 153) in human mast cells requires NF-kB activation. Biology and Pharmaceutical Bulletin 25 1165-1168

Kwon S, Newcomb RL a nd George SC (2001) Mechanisms of synergistic cytokine-induced nitric oxide production in human alveolar epithelial cells. Nitric Oxide 5 534-546

Kwon WJ, Kim SH, Park YO, Cho M, Kang CD, Lee G, An WG, Joo WH and Kim DW (2004) IKKg inhibits activation of NF-kB by NIK. Mol Cells 18 200-206

Kwon Y and Magnuson BA (2007) Aging alters acute apoptotic response to azoxymethane in the colon of rats. Experimental Gerontology in press

Kwon Yj, Genovesio A, Kim NY, Kim HC, Jung S, David-Watine B, Nehrbass U and Emans N (2007) High-content classification of nucleocytoplasmic import or export inhibitors.Journal of Biomolecular Screening in press

Kwon YK, Jun JM, Shin SW, Cho JW and Suh SI (2005) Curcumin decreases cell proliferation rates through BTG2-mediated cyclin D1 down-regulation in U937 cells. International Journal of Oncology 26 1597-1603

Kwon YW, Jang ER, Lee YM, Kim YS, Kwon KS, Jang HS, Oh CK and Kim KW (2000) Insulin-like growth factors II inducers interleutein-6expression via NF-kB activation in psoriasis. Biochemical and Biophysical Research Communications 278 312-317

Kwong KY, Literat A, Zhu NL, Huang HH, Li C, Jones CA and Minoo P (2004) Expression of transforming growth factor beta (TGF-beta1) in human epithelial alveolar cells: a pro-inflammatory mediator independent pathway. Life Sciences 74 2941-2957

Kye MJ, Spiess J and Blank T (2007) Transcriptional regulation of intronic calcium-activated potassium channel SK2 promoters by nuclear factor-kB and glucocorticoids.Molecular and Cellular Biochemistry in press

Kyrgidis A, Kountouras J, Zavos C and Chatzopoulos D (2005) New molecular concepts of Barrett’s esophagus: clinical implications and biomarkers. Journal of Surgical Research 125 189-212

Kyriakis JM (2001) Life-or-death decisions. Nature 414 265-266

Kyung TW, Lee JE, Shin HH and Choi HS (2008) Rutin inhibits osteoclast formation by decreasing reactive oxygen species and TNF-a by inhibiting activation of NF-kB. Experimental Molecular Medicine 40 52-58