Oral Pathogen ‘Hides’ From Immune System: Mechanisms Behind Inflammation and Oral Health

Caroline Genco, School of Medicine

The relationship between oral health and atherosclerosis has become a little clearer with newly published research showing how oral bacteria—the type your dentist has warned you about—contributes to and exacerbates vascular inflammation…

Expert quote:

“These bacteria make this modifiable lipid A on their surface and this functions as a decoy for the immune system. We made mutations in these lipids and showed that when you make one particular type of lipid you get lots and lots of inflammation. When you make another type of lipid, you only get very low-grade inflammation.”

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