Ongoing Research Projects

The research activities in the Center focus on investigating the impact of exercise and rehabilitation on the progression of disability in individuals with Parkinson’s disease.

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Currently Enrolling

Effort and Motivation Study in Persons with Parkinson Disease

The goal of this study is to determine the effects of motivation on walking and exercise in individuals with Parkinson’s Disease. This study involves one visit to BU, which includes some computer-based tasks and questionnaires, and 11 days of wearing a Fitbit during your normal daily routines to track steps.

For additional information, click here.
Interested? Contact the AMP Lab at or 617-358-2889

Emerald: Non-Invasive Health Monitoring

Emerald is a sensor that is mounted to the wall of a home and analyzes the home and can collect information (like falls, walking speed, and sleep stages). The main goal of this study is to evaluate the accuracy of a sensor on people with Parkinson disease. The long-term goal of the project is to use the device to monitor the progression of Parkinson disease and help provide better care.

Emerald: Non-Invasive Health Monitoring

For additional information, please visit
Interested? Contact Chen-Yu Hsu at

Soft Exosuits for Neurorehabilitation Study

The major goal of this project is to develop a lower-extremity suit to improve the walking and independence of mobility-impaired stroke survivors. The study will include one or more visits during which participants will assist with the design and development of the suit by providing information about the way they walk and testing the suit’s components.

Exosuit Image

For additional information, please visit:

Interested? Contact the Wyss Institute at or 617-432-8227

Impact of Physical Therapy

We are interested in studying the outcomes for individuals with Parkinson’s Disease and stroke who regularly participate in physical therapy. This study emphasizes how typical therapy translates into achieving patient goals in walking and gait patterns.

If you are interested in receiving our physical therapy services, please contact the Center for Neurorehabilitation at 617-353-7525.


No Longer Enrolling

Rehabilitation Enhancing Aging through Connected Health (REACH Pilot Study)

The main purpose of the project is to determine the effectiveness of a mobile health technology mediated exercise program in reducing disability and improving physical function in older adults with mobility decline over 1-year.

Spinal Cord Injury Virtual Coach to Promote Self-Care in Pressure Ulcer Prevention

The goal of this study is to develop and test the first-ever SCI Virtual Coach to provide support, education and coaching after inpatient rehabilitation to promote skin care management in persons post SCI. Feasibility will be evaluated in a proof of concept Phase I/II pilot study measuring acceptability, adherence and preliminary evidence of efficacy.

Application of a Training Module for Peer Coaches to promote exercise adherence in people with Parkinson disease

The goal of this study is to determine the impact of participation in a peer-coaching program, that can be done at home, on a person’s exercise patterns. The peer-coaching program involves assisting another person to reach his/her walking goals through education, goal setting, problem solving, and encouragement.

Eligible participants are assigned to one of two groups, based upon their current walking activity. Those that are peer coaches take a peer coach training program. Those that are peer mentees interact with their peer coach for 8 weeks via telephone conversations. Members of both groups also wear a pedometer to track their daily steps.

Telemedicine Intervention to Improve Physical Function in Persons with
Parkinson Disease

The goal of this study is to determine if a one-year home exercise program, centered on remote, real-time instruction and supervision, will reduce the rate of falls and improve strength and quality of life in patients with Parkinson Disease.

Mobile Health Technology to Promote Physical Activity in Persons with Parkinson Disease

In this study, eligible participants are randomly assigned to one of 2 groups, one group receives exercise handouts with pictures and instructions and the other group will receive an iPad mini with video demonstrations of the exercises. Both groups are prescribed strengthening and stretching exercises and a walking program, by a licensed physical therapist, to carry out for 6 months. The aim is to determine the effectiveness of the virtual versus print instructions on physical activity in individuals with Parkinson’s Disease.