Deepti Putcha, MA

Title
Fifth-year doctoral student, Clinical Psychology
Email
dputcha@bu.edu
Education
2011 M.A. Boston University
2008 B.A. University of Massachusetts at Amherst

Research Interests

I am investigating the cognitive, behavioral, and neural markers of early neurodegeneration using neuropsychological and neuroimaging (MRI, fMRI) methodologies). Recently, I’ve become interested in functional neural changes related to visuoperceptual changes (optic flow motion perception), and the functional reorganization of neurocognitive networks that occur in early stages of Parkinson’s disease.

Current Projects

I am currently working on my dissertation research, which focuses on the functional reorganization of large-scale core neurocognitive networks during the resting state in early stages of PD. I have found that the functional connectivity between networks important for high-level cognitive control, including the default-mode, central executive, and salience networks, is disrupted in PD prior to observable cognitive deficit or structural atrophy. I hope to defend this work in the spring of 2015.

Relevant Experience

As an undergraduate, I conducted research with the Work and Family Transitions Project at UMASS with Dr. Maureen Perry-Jenkins. There, we examined socio-emotional factors of child well-being by examining the family system. I was also involved in cognitive neuroscience research examining cognition and motor behavior of rhesus macaques under the supervision of Dr. Agnes Lacreuse.

For two years post-graduation I was a research assistant at Brigham and Women’s Hospital and Massachusetts General Hospital investigating the neural underpinnings of Alzheimer’s disease with Dr. Reisa Sperling using MRI and fMRI techniques.

Hobbies & Pastimes

I spend my time outside of grad school listening to live music around boston, swimming, playing guitar and piano, and reading science fiction books.

Publications

Putcha, D., Ross, R.S., Rosen, M.L., Cronin-Golomb, A., Somers, D.C., and Stern, C.E. (2014) Functional correlates of optic flow motion processing in Parkinson’s disease. Frontiers in Integrative Neuroscience, 8:57. doi: 10.3389

Putcha, D., Brickhouse, M., O’Keefe, K., Sullivan, C., Rentz, D., Marshall, G., Dickerson, B., and Sperling, R. (2011) Hippocampal hyperactivity associated with cortical thinning in Alzheimer’s disease signature regions in non-demented elderly adults. The Journal of Neuroscience, 31(48), 17680-8.

Putcha, D., O’Keefe, K., LaViolette, P., O’Brien, J., Greve, D., Locascio, J., Atri, A., Rentz, D., and Sperling, R. (2011). Reliability of fMRI Associative Encoding Memory Paradigm in Non-Demented Elderly Adults. Human Brain Mapping. doi:10.1002/hbm.21166

Vannini, P., Hedden, T., Becker, JA., Sullivan, C., Putcha, D., Rentz, D., Johnson, KA., Sperling, RA. (2011). Age and amyloid-related alterations in default network habituation to stimulus repetition. Neurobiology of Aging. doi:10.1016/j.neurobiolaging.2011.01.003

Drzezga, A., Becker, J.A., Van Dijk, K.R.A., Sreenivasan, A., Talukdar, T., Sullivan, C., Schultz, A.P., Sepulcre, J., Putcha, D., Greve, D., Johnson, K.A., and Sperling, R.A. (2011). Neuronal dysfunction and disconnection of cortical hubs in non-demented subject with elevated amyloid burden. Brain, 134:1635-46.

Becker, J.A., Hedden, T., Carmasin, J., Maye, J., Rentz, D., Putcha, D., Fischl, B., Greve, D.N., Marshall, G.A., Salloway, S., Marks, D., Buckner, R.L, Sperling, R.A., and Johnson, K.A. (2010). Amyloid-β associated cortical thinning in clinically normal elderly. Annals of Neurology, 69(6):1032-42.

Wang L, Laviolette P, O’Keefe K, Putcha D, Bakkour A, Koene R.A. Van Dijk, Maija Pihlajamäki, Bradford C. Dickerson, and Reisa A. Sperling (2010). Intrinsic connectivity between the hippocampus and posteromedial cortex predicts memory performance in cognitively intact older individuals. Neuroimage 51:910-7

Manuscripts in preparation

Putcha, D., Ross, R.S., Cronin-Golomb, A., Janes, A.C., Stern, C.E. (in preparation) Disrupted intrinsic functional coupling between large-scale distributed networks in Parkinson’s disease.

Putcha, D., Ross, RS., Rosen, M.L., Norton, D., Cronin-Golomb, A., Somers, D.C., and Stern, C.E. (2013) Diminished Optic Flow Activation in Parkinson’s Disease.

Published abstracts and presentations

Putcha, D., Jaywant, A., Ross, R.S., Cronin-Golomb, A., and Stern, C.E. (2013) “Dimensional versus Categorical assessment of motor symptoms in Parkinson’s disease: relation to cognition.” Poster presented at the annual Society for Neuroscience conference in San Diego, CA. 
 
Putcha, D., Ross, R.S., Somers, D.C., Cronin-Golomb, A., and Stern, C.E. (2013) “Frontostriatal connectivity and route navigation in older healthy adults and Parkinson’s disease patients.” Poster presented at the annual Human Brain Mapping conference in Seattle, WA.

Putcha, D., Ross, R.S., Rosen, M.L., Cronin-Golomb, A., Somers, D.C., and Stern, C.E. (2011). “Diminished V6 Activation in Response to Optic Flow in Parkinson’s Disease.” Poster presented at the annual Society for Neuroscience conference in Washington, D.C.

Putcha, D., Sullivan, C., O’Keefe, K., Schultz, A., Carmasin, J., Becker, J.A., Johnson, K., and Sperling, R. (2010). Resting Parietal Glucose Metabolism Related to Hippocampal Activation in Elderly Controls. Poster presented at the annual Human Brain Mapping conference in Barcelona, Spain.

Putcha, D., O’Keefe, K., LaViolette, P., Hamdi, I., O’Brien, J., Atri, A., and Sperling, R. (2009). Test-Retest of fMRI Activity in Hippocampus and Default Network in Non-demented Elderly Subjects. Poster presented at the annual Human Brain Mapping conference in San Francisco, CA.

Vannini, P., O’Brien, J., Putcha, D., O’Keefe, K., Pihlajamaki, M., LaViolette, P., Hamdi, I., Wang, L., Becker, A., Johnson, K., and Sperling, R.A. (2009). Successful Memory Retrieval Requires Increased Parietal Activity in Asymptomatic Older Adults with High Amyloid Burden. Alzheimer’s and Dementia, 5 (4), P100-P100.

Otolo, CM, Putcha, D, Chiavetta, MR and Lacreuse, A. (2008). Effects of testosterone on fine motor function in young male rhesus monkeys. Poster presented at Science Day, University of Massachusetts, Amherst, MA

Putcha, D., Smith, J., and Perry-Jenkins, M. (2008). Relationship between Marriage and Children’s Socio-emotional Well-being: A Longitudinal Analysis. Poster presented at the Undergraduate Research Conference at the University of Massachusetts at Amherst and presented at the annual conference of the American Psychological Association in Boston, MA.

Turner, E., Perry-Jenkins, M. & Putcha, D. (2007). Learning How to Fight: Connections Between Conflict Resolution Patterns in Marital and Sibling Relationships. Poster presented at the biennial conference of the Society for Research in Child Development in Boston, MA.