Boston University

Selected Publications

Selected Journal Papers

  1. Valencia-Burton, M. Shah, A. Sutin, J. Borogovac, A., McCullough, R. Cantor, C.R. Meller, A. and Broude, N.E. (2009) Spatiotemporal patterns and transcription kinetics of induced RNA in single bacterial cells, Proc. Natl. Acad. Sci. U.S.A. 106, 16399-16404 (download).
  2. Wanunu, M. Sutin, J. and A. Meller (2009) DNA Profiling Using Solid-State
    Nanopores: Detection of DNA-Binding Molecules, Nano Letters, 9, 3498-3502 (download).
  3. Wanunu, M. Sutin, J. McNally, B. Chow, A. and A. Meller (2008) DNA Translocation Governed by Interactions with Solid State Nanopores, Biophys. J. 95, 4716-25 (download).
  4. McNally, B. Wanunu, M. and A. Meller (2008) Electro-mechanical unzipping of individual DNA molecules using synthetic sub-2 nm pores, Nano Letters, 8, 3418-22 (download).
  5. Wanunu, M. Chakrabarti, B. Mathé, J. Nelson, D. R. and A. Meller (2008) Orientation-dependent interactions of DNA with an a-Hemolysin Channel, Phys Rev. E, 77, 031904 (download).
  6. Soni G. and A. Meller (2007) Progress Towards ultrafast DNA sequencing using solid state nanopores. Clin. Chem. 3, 1996-01
  7. Kim, M-J., B. McNally, K. Murata and A. Meller (2007) Characteristics of solid-state nanometer pores fabricated using transmission electron microscope (TEM) Nanotechnology, 18, 205302.
  8. Dudko, O., J. Mathé, A. Szabo, A. Meller, and G. Hummer (2007) Extracting kinetics from single-molecule force spectroscopy: Nanopore unzipping of DNA hairpins, Biophys. J., 92, 4188-4195 (download)
  9. Wanunu, M. and A. Meller (2007) Chemically Modified Solid-State
    Nanopores. Nano Letters, 7, 1580-85 (download), (also read Research Highlight, Nature, 447, 14 (2007)
  10. Hornblower, B., A. Coombs, R.D. Whitaker, A. Kolomeisky, Picone, S.J., A. Meller and M. Akeson (2007) Single-Molecule Analysis of DNA-Protein Complexes Using Nanopores. Nature Methods, 4, 315-317 DOI: 10.1038/nmeth1021 (download)
  11. Edel, J., J. Eid and A. Meller (2007) Accurate single molecule FRET efficiency determination for surface immobilized DNA using maximum likelihood calculated lifetimes. J. Phys. Chem B., 111, DOI: 10.1021/jp066530k (download)
  12. Kim, M-J., M. Wanunu, C.D. Bell and A. Meller (2006) Rapid Fabrication of Uniform Size Nanopores and Nanopore Arrays for Parallel DNA Analysis. Adv. Mater. 18, 3149-3153. (download)
  13. Jan Bonthuis, D., J. Zhang, B. Hornblower, J. Mathé, B.I. Shklovskii and A. Meller (2006) Self-Energy-Limited Ion Transport in Subnanometer Channels. Phys. Rev. Lett. 97, 128104. (download)
  14. Mathé, J., A. Arinstein, Rabin Y. and A. Meller (2006) Equilibrium and irreversible unzipping of DNA in a nanopore, Europhys. Lett. 73 (1), 128-134 (download)
  15. Viasnoff, V., A. Meller and H. Isambert (2006) DNA nanomechanical switches under folding kinetics control. Nano Letters, 6, 101-104 (download)
  16. Sabanayagam, C.R., J.S. Eid and A. Meller (2005) Long time scale blinking kinetics of cyanine fluorophores conjugated to DNA and its effect on Förster resonance energy transfer. J. Chem. Phys. 123, 224708. (download)
  17. Mathé, J., A. Aksimentiev, D.R. Nelson, K. Schulten and A. Meller (2005) Orientation discrimination of single-stranded DNA inside the alpha-hemolysin membrane channel. Proc. Natl. Acad. Sci. U.S.A. 102, 12377-12382. (download)
  18. Sabanayagam, C.R., J.S. Eid and A. Meller (2005) Using fluorescence resonance energy transfer to measure distances along individual DNA molecules: Corrections due to nonideal transfer. J. Chem. Phys. 122, 061103. (download)
  19. Mathé, J., H. Visram, V. Viasnoff, Y. Rabin and A. Meller (2004) Nanopore unzipping of individual DNA hairpin molecules. Biophys. J. 87, 3205-3212. (download)
  20. Sabanayagam, C.R., J.S. Eid and A. Meller (2004) High-throughput scanning confocal microscope for single molecule analysis. Appl. Phys. Lett. 84, 1216-1218 (download).
  21. Bates, M., M. Burns and A. Meller (2003) Dynamics of single DNA molecules actively controlled inside a membrane channel. Biophys. J. 84, 2366-2372 (download).
  22. Meller, A., L. Nivon and D. Branton (2001) Voltage-Driven DNA Translocations through a Nanopore. Phys. Rev. Lett. 86, 3435-3438 (download).
  23. Meller, A. and D. Branton (2002) Single molecule measurements of DNA transport through a nanopore. Electrophoresis 23, 2583-2591.
  24. Meller, A., L. Nivon, E. Brandin, J. Golovchenko and D. Branton (2000) Rapid nanopore discrimination between single polynucleotide molecules. Proc. Natl. Acad. Sci. U.S.A. 97, 1079-1084 (download).
  25. Meller, A., J. Stavans, T. Gisler, and D.A. Weitz. (1999) Viscoelasticity of Depletion-Induced Gels in Emulsion-Polymer Systems. Langmuir 15:1918-1922.
  26. Tlusty, T., A. Meller, and R. Bar-Ziv. (1998) Optical gradient forces of strongly localized fields. Phys. Rev. Lett. 81:1738-1741.
  27. Meller, A., R. Bar-Ziv, T. Tlusty, E. Moses, J. Stavans and S.A. Safran. (1998). Localized dynamic light scattering: A new approach for dynamic measurements in optical microscopy. Biophys. J. 74:1541-1548.
  28. Bar-Ziv, R., A. Meller, T. Tlusty, E. Moses, J. Stavans and S.A. Safran (1997). Localized Dynamic Light Scattering: Probing Single Particle Dynamics at the Nanoscale. Phys. Rev. Lett. 78:154-157.
  29. Meller, A. and J. Stavans (1996). Stability of Emulsions with Nonadsorbing Polymers. Langmuir 12:301-304.
  30. Steiner, U., A. Meller, and J. Stavans (1995). Entropy Driven Phase Separation in Binary Emulsions. Phys. Rev. Lett. 74:4750-4753.
  31. Meller, A. and J. Stavans. (1992). Glass transition and phase diagrams of strongly interacting binary colloidal mixtures. Phys. Rev. Lett. 68:3646-3649.

Selected Reviews and Book chapters

  1. Wanunu, M. G. Soni and A. Meller (2009) Single molecule studies of nucleic acids interactions using nanopores, In: Handbook of Single-Molecule Biophysics, Springer, in press
  2. Branton D. et. al. (2008) The potential and challenges of nanopore sequencing, Nature Biotechnology 26, 1146-53.
  3. Wanunu, M. and A. Meller (2008) Single Molecule Analysis of Nucleic Acids and DNA-protein Interactions using Nanopores, Laboratory Manual on Single Molecules, Eds. P. Selvin and T. Ha, Cold Spring Harbor Press.
  4. Lee, J.W. and A. Meller (2006). Rapid DNA Sequencing by Direct Nanoscale Reading of Nucleotide Bases on Individual DNA chains. In: Perspectives in Bioanalysis. K. Mitchelson (Ed.), Elsevier. (download)
  5. Meller, A. (2003) Dynamics of polynucleotide transport through nanometre-scale pores. J. Phys.: Condens. Matter 15, R581-R607. (download)