Ph.D., University of Colorado at Boulder
phone: (617) 358-4406
office: 110 Cummington Mall, ENG 219
Mechanical behavior of soft biological tissue * Cardiovascular mechanics * Multi-scale modeling of biological composites * Micro- and nano- mechanics of thin film devices
Professor Zhang’s research focuses on understanding the mechanical behavior of soft biological tissues and composites at multi-scale using both experimental techniques and advanced computational modeling. Her research integrates the knowledge in biology, nonlinear solid mechanics, and finite element modeling, especially of complex materials and constitutive behavior. Professor Zhang believes that the interplay between fundamental analysis and clinical application will provide the greatest gains. Through her research, she hopes to provide insights on understanding the relationship between microscopic biological processes and changes in macroscopic tissue mechanics due to diseases, and help the development of diagnostic, therapeutic, and pharmaceutical techniques. Her research interest also lies in the mechanical characterization and multi-scale modeling of micro- and nano-electromechanical systems.
Professor Zhang’s current research projects are in the characterization of the biomechanical behavior of native and engineered blood vessels using an integrative approach of mechanical testing combined with multi-scale modeling, understanding of the inelastic deformation mechanisms in micro- and nano-electromechanical systems and relations of these behaviors to design, analysis, and device performance.
- Zou, Y. and Zhang, Y., ” An Experimental and Theoretical Study on the Anisotropy of Elastin Network,” Annals of Biomedical Engineering, Vol. 37, pp. 1572-1583, 2009.
- Wei, D. and Zhang, Y., “Friction Between a-Al2O3(0001) Surfaces and the Effects of Surface Hydroxylation,” Surface Science, Vol. 603, pp. L95-L98, 2009.
- Zhang, Y. and Dunn, M. L., “Patterned bilayer plate microstructures subjected to thermal loading: Deformation and Stresses,” International Journal of Solids and Structures, Vol. 46, pp. 125-134, 2009.
- Lin, I-K, Zhang, X., and Zhang, Y., “Thermomechanical Behavior and Microstructural Evolution of SiNx/Al Bimaterial Microcantilevers,” Journal of Micromechanics and Microengineering, Vol. 19, pp. 085010, 2009.
- Lin, I-K, Zhang, Y., and Zhang, X., “The Deformation of Microcantilever-Based Infrared Detectors During Thermal Loading,” Journal of Micromechanics and Microengineering, Vol. 18, pp. 075012, 2008.
- Zhang, Y., Dunn, M. L., Hunter, S. K., Lee, P. F., Lanning, C., Dunbar, D., and Shandas R., “Application of a microstructural constitutive model of pulmonary artery to patient-specific studies: validation and effect of orthotropy,”Journal of Biomechanical Engineering, Vol. 129, pp. 193-201, 2007.
- Hunter, K. S., Lanning, C.J., Chen, S-Y J., Zhang, Y., Garg, R., Ivy, D. D., Shandas, R., “Simulations of Congenital Septal Defect Closure and Reactivity Testing in Patient-Specific Models of the Pediatric Pulmonary Vasculature: A 3D Numerical Study with Fluid-Structure Interaction,” J. Biomech. Engr., Vol. 128, pp. 564-572, 2006.
- Pajot, J., Maute, K., Zhang, Y., and Dunn, M. L., “Design of Patterned Multilayer Films with Eigenstrains by Topology Optimization,” International Journal of Solids and Structures, Vol. 43, pp. 1832-1853, 2006.