Professor Porter’s overall goal of his research program is to push the application of ultrasound technology in new and exciting directions. Applications could include using ultrasound technology to test the growth of cancer and drug delivery through microscopic carriers.

Profesor Porter’s lab is working on new ultrasound technologies and novel chemical formulations for assessing tissue perfusion, targeted contrast enhancement of diseases in ultrasound images, and improving the uptake and activity of drugs while reducing adverse side effects.

Selected Publications

• Gong Y, Cabodi M, Porter TM. Relationship between size and frequency-dependent attenuation of monodisperse populations of lipid-coated microbubbles, Bubble Science, Engineering, and Technology ), Vol. 2, No. 2, 41-47, 2010.
• Zhang P, Porter T. An in vitro study of a phase-shift nanoemulsion: a potential nucleation agent for bubble-enhanced HIFU tumor ablation, Ultrasound Med Biol, Vol 36, No. 11, 1856-1866, 2010.
• Ta T, Convertine A, Reyes C, Stayton P, Porter T. Thermosensitive liposomes modified with poly(N-isopropylacrylamide-co-propylacrylic acid) copolymers for triggered release of Doxorubicin, Biomacromolecules, Vol. 11, 1915-1920, 2010.
• Gong Y, Cabodi M, Porter TM. Measurement of the attenuation coefficient for monodisperse populations of ultrasound contrast agents, Proceedings IEEE Eng Med Biol Soc. , 1964-1966, 2009.
• Smith DAB, Porter TM, Martinez J, Huang SL, MacDonald RC, McPherson DD, Holland CK. Destruction thresholds of echogenic liposomes with clinical diagnostic ultrasound, Ultrasound Med Biol , Vol. 33, No. 5, 797-809, 2007.
• Porter TM, Smith DAB, Holland CK. Acoustic techniques for assessing the Optison destruction threshold, J Ultrasound Med , Vol. 25, No. 12, 1519-1529, 2006.
• Datta S, Coussios CC, McAdory LE, Tan J, Porter TM, De Courten-Myers G, Holland CK. Correlation of cavitation with ultrasound enhancement of thromobolysis,Ultrasound Med Biol , Vol. 32, Issue 8, 1257-1267, 2006.
• Porter TM, Murthy N, Mourad PD, Stayton PS, Hoffman AS, and Crum LA.  Control of cavitation-induced hemolysis with a surface-active polymer, Acoustics Research Letters Online (2005), Vol. 6, Issue 3, 201-206, 2005.
• Porter TM, Crum LA, Black F, Stayton PS, and Hoffman AS.  The effect of polymer surface activity on cavitation nuclei stability against dissolution, J Acoust Soc Am, Vol. 116, No. 2, 721-728, 2004.
• Mourad P.D., Murthy N, Porter T.M., Poliachik S.L., Crum L.A., Hoffman A.S., and Stayton P.S., Focused Ultrasound and Poly(2-ethylacrylic acid) Act Synergistically to Disrupt Lipid Bilayers In Vitro, Macromolecules Vol. 34, 2400-2401, 2001.