R. Glynn Holt, Ph.D.

Photo of R. Glynn Holt

Associate Professor

Ph.D., University of Mississippi

phone: (617) 353-9594
email: rgholt@bu.edu
office: 110 Cummington Mall, ENG 417

Research Interests

Physical Acoustics * Sonoluminescence * Rheology of Foam * Biomedical Acoustics and High-Intensity Focused Ultrasound

Professor Glynn Holt’s research interests span a range of disciplines and involve physical acoustics, interfacial wave phenomena, nonlinear drop and bubble dynamics, and surface and bulk rheology. An experimentalist, he uses acoustic levitation as a non-contact probe of the behavior of free liquid surfaces. Some of his efforts are geared toward studying the effects of gravity on fluid problems, and he has been an investigator on liquid-drop experiments conducted on board the space shuttle.

Professor Holt is currently involved in three research projects: an investigation of bubble-mediated bioeffects of high-intensity focused ultrasound with potential clinical applications to tumor therapy and hemostasis (Army/NCPA); an investigation of the role gravity plays in sonoluminescence–the phenomenon in which short pulses of light are emitted by collapsing bubbles (NASA); and a project to explore the mechanical and acoustic behavior of aqueous foams near the order-disorder transition utilizing a unique acoustic levitation/modal analysis technique (NASA).

Professor Holt, a recipient of an Office of Naval Research Graduate Fellowship and a DAAD research fellowship in Germany, was selected by NASA as a payload specialist (alternate) crew member for the flight of the Second United States Microgravity Laboratory, which flew aboard the space shuttle Columbia in 1995.

Selected Publications
Zachary Waters, Benjamin Dzikowicz, R. Glynn Holt, Ronald Roy, “Sensing a buried resonant object by a single-channel time reversal,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 56, no. 7, July 2009.
2. Caleb H. Farny, R. Glynn Holt, and Ronald Roy, “Temporal and spatial detection of HIFU-induced inertial and hot-vapor cavitation with a diagnostic ultrasound system,” Ultrasound in Medicine and Biology,  Vol. 35, Issue 4, Pages 603-615, April 2009.
3. Romona Gerogescu, Damir Khismatullin, R. Glynn Holt, Jean Luc Castagner, Ousama A’amar, Irving J. Bigio, “Design of a system to measure light scattering from individual cells excited by an acoustic wave,” Optics Express, 16 (6), p. 3496, 2008.
4. Charles R. Thomas, Caleb H. Farny, Constantin C. Coussios, Ronald A. Roy and R. Glynn Holt, “Dynamics and control of cavitation during high-intensity focused ultrasound application,” Acoustics Research Letters Online 6 (3), 182-187, 2005.
5. Caleb H. Farny, Tianming Wu, R. Glynn Holt, Todd W. Murray, and Ronald A. Roy, “Nucleating cavitation from laser-illuminated nano-particles,” Acoustics Research Letters Online 6 (3), 138-143, 2005.
6. Xinmai Yang, Ronald A. Roy, and R. Glynn Holt, “Bubble dynamics and size distributions during focused ultrasound insonation,” J. Acoust. Soc. Am. 116 (6), 3423-3431, 2004.
7. Charles R. Thomas, Ronald A. Roy, and R. Glynn Holt, “Bubble dynamics near the onset of single0bubble sonoluminescence,” Phys Rev E, 70, 066301, 2004.
8. Jinlan Huang, R. Glynn Holt, Robin O. Cleveland, and Ronald A. Roy, “Experimental validation of a tractable numerical model for focused ultrasound heating in flow-through tissue phantoms,” J. Acoust. Soc. Am. 116 (4) 2451-2458, 2004.
  • Ran, W., J.R. Saylor and R.G. Holt, “Improved particle scavenging by a combination of ultrasonics and water sprays”, Journal of Aerosol Science 67C, 104 (2014), http://dx.doi.org/10.1016/j.jaerosci.2013.08.009
  • Robert D. Valtierra, R. Glynn Holt, Danielle Cholewiak and Sofie M. Van Parijs, “Calling depths of baleen whales from single sensor data: Development of an autocorrelation method using multipath localization” J. Acoust. Soc. Am. 134, 2571 (2013).
  • Jonathan R. Sukovich, Ashwin Sampathkumar, Phillip A. Anderson, R. Glynn Holt, Yuri A. Pishchalnikov, and D. Felipe Gaitan, “Temporally and spatially resolved imaging of laser-nucleated bubble cloud sonoluminescence.” Phys. Rev. E 85, 056605 (2012)
  • Phillip Anderson, A. Sampathkumar, Todd W. Murray, D. Felipe Gaitan, and R. Glynn Holt, “Optical nucleation of bubble clouds in a high pressure spherical resonator”, J. Acoust. Soc. Am. 130, 3389 (2011).
  • Mohammad A. Alibakhshi and R. Glynn Holt, “Suppressing shape instabilities to discover the Bjerknes force instability”, J. Acoust. Soc. Am. 130, 3321 (2011).
  • Tianming Wu, Caleb H. Farny, Ronald A. Roy, and R. Glynn Holt, “Modeling cavitation nucleation from laserilluminated nanoparticles subjected to acoustic stress”, J. Acoust. Soc. Am. 130, 3252 (2011).
  • Charles R. Thomas, Ronald A. Roy, and R. Glynn Holt, “Ambient acceleration dependence of single-bubble sonoluminescence”, J. Acoust. Soc. Am. 130, 3282 (2011).
  • Jonathan Robert Sukovich, Ashwinkumar Sampathkumar, and R. Glynn Holt, “Pressure Dependence of Laser- Induced Dielectric Breakdown in Water”, IEEE Journal of Quantum Electronics 47 (10), 1297 – 1303, (2011).
  • D. Felipe Gaitan, Ross A. Tessien, Robert A. Hiller, Joel Gutierrez, Corey Scott, Henry Tardif, Brant Callahan, Thomas J. Matula, Lawrence A. Crum, R. Glynn Holt, Charles C. Church and Jason L. Raymond, “Transient cavitation in high-quality-factor resonators at high static pressures”, J. Acoust. Soc. Am. 127 (6), 3456-3465, (2010).
  • Parag V. Chitnis, Nicholas J. Manzi, Robin O. Cleveland, Ronald A. Roy and R. Glynn Holt, “Mitigation of Damage to Solid Surfaces From the Collapse of Cavitation Bubble Clouds”, Journal of Fluids Engineering 132, p. 051303-1 – 051303-6, (2010)