ME Department Seminar: Heather Clark (Northeastern University)

11:00 am on Friday, November 15, 2013
RM 245, 110 Cummington Mall
Fluorescent Nanosensors for Analysis in Cellular and Tissue Environments -- The limited available analytical tools for measuring real-time ion and small molecule flux at a cellular level have clarified cell physiology and signaling for a small number of analytes. Modular nanosensors may greatly expand the available library of probes by combining sensing chemistries within the core of a hydrophobic nanoparticle. This tunable analytical platform produces is already capable of measuring sodium, potassium, glucose, histamine, and other bio-analytes in real time. Implementing these probes in biological studies will quantitatively image the biochemical environment of neural cells and monitor physiologically relevant bio-analytes in vivo for chronic illness management.