ME Department Seminar: Joseph Charest (Draper Laboratory)

11:00 am on Friday, November 30, 2012
Rm 245
Replicating organ and tissue function with microfabricated systems: Organ failure is an obviously serious medical condition with a very widespread impact. To limit organ failure, in vitro predictive models replicate organ and tissue function to screen pharmaceuticals for toxicity to organs and test efficacy of organ therapies. To treat patients with failing or failed organs, organ-assist medical devices replicate functions of organs by processing patient’s blood to supplement the native organ function. In both cases, microfabricated systems can mimic components of native tissue resulting in realistic in vitro models as well as medical devices with improved efficiencies and decreased side effects.