2009
Ma J, Waxman DJ. Dominant effect of antiangiogenesis in combination therapy involving cyclophosphamide and axitinib. Clin Cancer Res. 2009; 15(2):578-88.
Repetny KJ, Zhou X, Holodick NE, Rothstein TL, Hansen U. Binding of LBP-1a to specific immunoglobulin switch regions in vivo correlates with specific repression of class switch recombination. Eur J Immunol, 2009; 39:1387-1394.
Bass, B.P., Tanner, E.A., Mateos San Martín, D., Blute, T., Kinser, R.D., Dolph, P.J. and McCall, K. Cell-autonomous requirement for DNaseII in non-apoptotic cell death, Cell Death and Differentiation 2009, in press.
Pritchett, T.L., Tanner, E.A. and McCall, K. Cracking open cell death in the Drosophila ovary, Apoptosis, 2009, in press; invited review
Hansen U, Owens L, Saxena UH Transcription factors LSF and E2Fs: Tandem cyclists driving G0 to S? Cell Cycle 2009, in press; invited review.
Potter, D.R., Jiang, J. & Damiano, E.R. The recovery time course of the endothelial-cell glycocalyx in vivo and its implications in vitro. Circulation Research 2009; in press, invited manuscript.
2008
Terragni J, JR Graham, KW Adams, MW Schaffer, JW Tullai & GM Cooper. 2008. Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NF-kB transcription factors. BMC Cell Biology 9: 6
Doloff JC, Waxman DJ, & Jounaidi Y. hTERT-promoter driven oncolytic adenovirus with E1B-19 kDa and E1B-55 kDa gene deletions. Human Gene Therapy 2008; 19: 1383-1399
Chin M, Herscovitch M, Zhang N, Waxman DJ, Gilmore TD. Overexpression of an activated REL mutant increases the transformed state of BJAB human B-cell lymphoma cells and alters their gene expression profile. Oncogene. 28: 2100-2111
Holloway MG, Miles GD, Dombkowski AA, Waxman DJ. Liver-specific hepatocyte nuclear factor-4alpha deficiency: greater impact on gene expression in male than in female mouse liver. Mol Endocrinol. 2008; 22(5):1274-86.
Ma J, Waxman DJ. Combination of antiangiogenesis with chemotherapy for more effective cancer treatment. Mol Cancer Ther. 2008; 7(12):3670-84. Review.
Herscovitch M, W Comb, T Ennis, K Coleman, S Yong, B Armstead, D Kalaitzidis, S Chandani & TD Gilmore. 2008. Intermolecular disulfide bond formation in the NEMO dimer requires Cys54 and Cys347. Biochemical and Biophysical Research Communications 367: 103-108
Holloway MG, GD Miles, AA Dombkowski & DJ Waxman. 2008. Liver-specific HNF4{alpha}-deficiency: greater impact on gene expression in male than in female mouse liver. Molecular Endocrinology, in press
Ma J & DJ Waxman. 2008. Modulation of the antitumor activity of metronomic cyclophosphamide by the angiogenesis inhibitor axitinib. Molecular Cancer Therapeutics 7: 79-89
Reynolds JG, SA McCalmon, JA Donaghey & FJ Naya. 2008. Deregulated PKA signaling and myospryn expression in muscular dystrophy. Journal of Biological Chemistry, 283: 8070-8074
2007
Andken BB, I Lim, G Benson, JJ Vincent, MT Ferenc, B Heinrich, LA Jarzylo, HY Man & JO Deshler. 2007. 3'-UTR SIRF: a database for identifying clusters of short interspersed repeats in 3' untranslated regions. BMC Bioinformatics 8: 274
Adams KW & GM Cooper. 2007. Rapid turnover of Mcl-1 couples translation to cell survival and apoptosis. Journal of Biological Chemistry 282: 6192-6200
Bass BP, K Cullen & K McCall. 2007. The axon guidance gene lola is required for programmed cell death in the Drosophila ovary. Developmental Biology 304: 771-785
Baum JS, E Arama, H Steller & K McCall. 2007. The Drosophila caspases Strica and Droncfunction redundantly in programmed cell death during oogenesis. Cell Death and Differentiation 14: 1508-1517
Clodfelter KH, GD Miles, V Wauthier, MG Holloway, X Zhang, P Hodor, WJ Ray & DJ Waxman. 2007. Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis. Physiological Genomics 31: 63-74
Holloway MG, Y Cui, EV Laz, A Hosui, L Hennighausen & DJ Waxman. 2007. Loss of sexually dimorphic liver gene expression upon hepatocyte-specific deletion of Stat5a-Stat5b locus. Endocrinology 148 1977-1986
Laz EV, MG Holloway, CS Chen & DJ Waxman. 2007. Characterization of three growth hormone-responsive transcription factors preferentially expressed in adult female liver. Endocrinology 148: 3327-3337
Ma J & DJ Waxman. 2007. Collaboration between hepatic and intratumoral prodrug activation in a P450 prodrug-activation gene therapy model for cancer treatment. Molecular Cancer Therapeutics 6: 2879-2890
O’Lone R, K Knorr, IZ Jaffe, ME Schaffer, PGV Martini, RH Karas, J Bienkowska, ME Mendelsohn & U Hansen. 2007. Estrogen receptors alpha and beta mediate distinct pathways of vascular gene expression, including genes involved in mitochondrial electron transport and generation of reactive oxygen species. Molecular Endocrinology 21:1281-1296
Peterson JS, BP Bass, D Jue, A Rodriguez, JM Abrams & K McCall. 2007. Non-canonical cell death pathways function in Drosophila oogenesis. Genesis 45: 396-404
Pezza JA, JD Stopa, EM Brunyak, KN Allen & DR Tolan. 2007. Thermodynamic analysis shows conformational coupling and dynamics confer substrate specificity in fructose-1,6-bisphosphate aldolase. Biochemistry 46: 13010-13018
Reynolds JG, SA McCalmon, T Tomczyk & FJ Naya. 2007. Identification and mapping of protein kinase A binding sites in the costameric protein myospryn. Biochimica Biophysica Acta 1773: 891-902
Starczynowski DT, H Trautman, C Pott, L Harder, N Arnold, JA Africa, JR Leeman, R Seibert & TD Gilmore. 2007. Mutation of an IKK phosphorylation site within the transactivation domain of REL in two patients with human B-cell lymphoma enhances REL’s in vitro transforming activity. Oncogene 26: 2685-2694
Sullivan JC, D Kalaitzidis, TD Gilmore & JR Finnerty. 2007. Rel homology domain-containing transcription factors in the cnidarian Nematostella vectensis. Development Genes and Evolution 217: 63-72
Tullai JW, J Chen, ME Schaffer, E Kamenetsky, S Kasif & GM Cooper. 2007. GSK-3b mediates repression of CREB target genes in quiescent cells. Journal of Biological Chemistry 282: 9482-9491
Tullai JW, ME Schaffer, S Mullenbrock, G Sholder, S Kasif & GM Cooper. 2007. Immediate-early and delayed primary response genes are distinct in function and genomic architecture. Journal of Biological Chemistry 282: 23981-23995
2006
Clodfelter KH, MG Holloway, P Hodor, SH Park, WJ Raj & DJ Waxman. 2006. Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis. Molecular Endocrinology 20: 1333-1351
Cronin MA , Lieu M-H, Tsunoda S: Two Stages of Light-Dependent TRPL-Channel Translocation in Drosophila Photoreceptors. J Cell Sci. 2006; 119:2935-2944.
Durham, J. T., O. M. Brand, M. Arnold, J. G. Reynolds , L. Muthukumar, H. Weiler, J. A. Richardson, and F. J. Naya. 2006. Myospryn is a direct transcriptional target for MEF2A that encodes a striated muscle, alpha-actinin-interacting, costamere-localized protein. Journal of Biological Chemistry 281:6841-6849.
Gilmore TD & M Herscovitch . 2006. Inhibitors of NF-kB signaling: 785 and counting. Oncogene 25: 6887-6899.
Holloway MG , Laz EV, Waxman DJ. 2006. Co-dependence of GH-responsive, sexually dimorphic hepatic gene expression on STAT5b and HNF4a. Molec Endocrinol, Mar;20(3):647-60.
Huang, H.-T., O.M. Brand, M. Mathew, C. Ignatiou, E.P. Ewen, S.A. McCalmon , and F.J. Naya. 2006. Myomaxin is a novel transcriptional target of MEF2A that encodes an alpha-actinin-interacting protein. Journal of Biological Chemistry. In press.
Liang M-C , S Bardhan, EA Pace, D Rosman, JA Beutler, JA Porco Jr & TD Gilmore. 2006. Inhibition of transcription factor NF-kB signaling proteins IKKbeta and p65 through specific cysteine residues by epoxyquinone A monomer: correlation with its anti-cancer cell growth activity. Biochemical Pharmacology: 71: 634-645.
Liang M-C , S Bardhan, JA Porco Jr & TD Gilmore. 2006. The synthetic epoxyquinoids jesterone dimer and epoxyquinone A monomer induce apoptosis and inhibit REL (human c-Rel) DNA binding in an IkBalpha-deficient diffuse large B-cell lymphoma cell line. Cancer Letters 241: 69-78.
Sawyer, S. J ., K. A. Gerstner, and G. V. Callard. 2006. Real-time PCR analysis of cytochrome P450 aromatase expression in zebrafish: Gene specific tissue distribution, sex differences, developmental programming, and estrogen regulation. General and Comparative Endocrinology 147:108-117.
Seo, K.-Y., Nagalingam, A, Shadi Miri, Jun Yin , Alexander Kolbanovskiy, Anant Shastry, and Loechler, E.L. 2006. Mirror Image Stereoisomers of the Major Benzo[a]pyrene N2-dG Adduct Are Bypassed by Different Lesion-Bypass DNA Polymerases in E. coli DNA Repair 5, 515 - 527.
Starzynowski DT , H Trautmann, C Pott, L Harder, N Arnold, JA Africa, JR Leeman, R Siebert & TD Gilmore. 2006. Mutation of an IKK phosphorylation site within the transactivation domain of REL in two patients with B-cell lymphoma enhances REL's in vitro transforming activity. Oncogene: in press.
2005
Baum, JS , JP St. George, and K McCall. Programmed cell death in the germline, Seminars in Cell and Developmental Biology 16:245-59, (2005). Link
Choo, S, B Heinrich, JN Betley, Z Chen, and JO Deshler. Evidence for Common Machinery Utilized by the Early and Late RNA Localization Pathways in Xenopus Oocytes. Developmental Biology 278, 103-117, (2005).Link .
Kalaitzidis D and TD Gilmore. Transcription factor cross-talk: Estrogen receptor and NF-kB. Trends in Endocrinology and Metabolism 16:46-52, (2005). Link
Lee JJ and EP Widmaier. Gene array analysis of the effects of chronic adrenocorticotropic hormone in vivo on immature rat adrenal glands. J Ster Biochem Mol Biol, 96:31-44, (2005). Link
Liang M-C , S Bardhan, JA Porco Jr & TD Gilmore. The synthetic epoxyquinoids jesterone dimer and epoxyquinone A monomer induce apoptosis and inhibit REL (human c-Rel) DNA binding in an IkBa-deficient diffuse large B-cell lymphoma cell line. Cancer Letters, (2005). Link
Starczynowski DT , JG Reynolds & TD Gilmore. Mutations of tumor necrosis factor alpha-responsive serine residues within the C-terminal transactivation domain of human transcription factor REL can enhance its in vitro transforming ability. Oncogene (2005). Link
Hong, Z, B Chasan, R Bansil, BS Turner , K Bhaskar, N Afdhal. Atomic force microscopy reveals conformational change and aggregation of gastric mucin at low pH Biomacromolecules. November-December (2005) Link
2004
Cronin MA , F Diao , S Tsunoda. The Light-Dependent Subcellular Translocation of Gq a in Drosophila Photoreceptors is Facilitated by the Photoreceptor-Specific Myosin III, NINAC. J. Cell Sci.; 117: 4797-4806, (2004). Link
Wiwi CA, M Gupte , DJ Waxman. Sexually dimorphic P450 gene expression in liver-specific hepatocyte nuclear factor 4a-deficient mice. Molec Endocrinol 18, 1975-1987 , (2004). Link
Kalaitzidis D , J Ok, L Sulak II, D Starczynowski & TD Gilmore. Characterization of a human REL-estrogen receptor fusion protein with a reverse conditional transforming activity in chicken spleen cells. Oncogene 23:7580-7587, (2004). Link
Gilmore TD, D Kalaitzidis , M-C Liang & DT Starczynowski .The c-Rel transcription factor and B-cell proliferation: a deal with the devil. Oncogene 23:2275-2286, (2004). Link
Raff H, JJ Lee , M Oaks, EP Widmaier, and W Engeland. Basal and ACTH-stimulated corticosterone in the neonatal rat exposed to hypoxia from birth: modulation by chemical sympathectomy. Endocrinology 145:79-86, (2004). Link
Lee J , PI Eisenberg, V Papadopoulos, J Wang, and EP Widmaier. Developmental changes in adrenal steroidogenesis and in expression of proteins associated with steroidogenesis in the postnatal rat. Endocrinology 145:2165-2173, (2004).Link
Arakaki TL , JA Pezza, MA Cronin, CE Hopkins , DB Zimmer, DR Tolan and KN Allen . Structure of human brain fructose 1,6-bisphosphate aldolase: Linking isozyme structure with function. Protein Science 12: 3077-3084, (2004). Link
Pezza JA , DN Allen and DR Tolan. Intein-mediated Purification of a Recombinantly Expressed Peptide. Chem. Commun. (21):2412-2413, (2004).Link
Rajamani D , S Thiel, S Vajda, CJ Camacho. Anchor residues in protein-protein interactions. Proc. Natl. Acad. Sci. USA; 101(31):11287-92, (2004). Link
Shipley JM , CH Hurst, SS Tanaka, FL DeRoos, JL Butenhoff, AM Seacat, DJ Waxman. Trans-activation of PPARa and induction of PPARa target genes by perfluorooctane-based chemicals. Toxicol Sci 80 , 151-160, (2004).
Shipley JM , DJ Waxman. Simultaneous, bi-directional inhibitory cross-talk between PPAR and STAT5b. Toxicol Appl Pharmacol 199, 275-284 , (2004) . Link
Celli, J, B Gregor, BS Turner , N Afdhal, R Bansil, S Erramilli, Viscoelastic. Properties and dynamics of porcine gastric mucin Biomacromolecules 6(3) 1329-1333, (2004).Link
Yin, J ., K.-Y Seo, and EL Loechler. A role for DNA polymerase V in G->T mutagenesis from the major benzo[a]pyrene N2-dG adduct when studied in a 5'-TGT sequence in Escherichia coli. DNA Repair 3, 323-334, (2004). Link
2003
Laundrie*, B, Peterson*, JS, Baum *, J Chang, D Fileppo, SR Thompson, and K McCall. Germline cell death is inhibited by P- element insertions disrupting the dcp-1/pita nested gene pair in Drosophila. Genetics 165: 1881-1888, (2003). *co-first authors Link
Raff H, JJ Hong , MK Oaks, and EP Widmaier. Adrenocortical responses to ACTH in the neonatal rat: the effect of hypoxia from birth on corticosterone, StAR, and PBR. Am J Physiol Regul Integr Comp Physiol 284: R78-R85, (2003). Link
Liang M-C , S Bardhan, C Li, EA Pace, JA Porco Jr & TD Gilmore. Jesterone dimer, a synthetic derivative of the fungal metabolite jesterone, blocks activation of Nuclear Factor kB by inhibiting Inhibitor of kB kinase. Molecular Pharmacology 64:123-131, (2003). Link
Pezza JA KH Choi, TZ Berardini, PT Beernink, KN Allen and DR Tolan. Spatial clustering of isozyme-specific residues reveals unlikely determinants of isozyme specificity in fructose-1,6-bisphosphate aldolase. J Biol Chem.;278(19):17307-17313, (2003). Link
Starczynowski D , JG Reynolds & TD Gilmore. Deletion of either C-terminal transactivation subdomain enhances the in vitro transforming activity of human transcription factor REL in chicken spleen cells. Oncogene 22: 6928-6936, (2003).
Link
Gilmore TD, J Jean-Jacques, R Richards, C Cormier, J Kim & D Kalaitzidis . Stable expression of the avian retroviral oncoprotein v-Rel in avian, mouse, and dog cell lines. Virology 316:9-16, (2003). Link
Shipley JM , DJ Waxman. Down-regulation of STAT5b transcriptional activity by ligand-activated PPARalpha and PPARgamma. Molec Pharmacol 64:355-364, (2003). Link
