A new discussion of clinical needs and current advancements in point of care technologies for sexually transmitted infections. Click on the link for the open access version of the paper. Point-of-Care Sexually Transmitted Infection Diagnostics: Proceedings of the STAR Sexually Transmitted Infection—Clinical Trial Group Programmatic Meeting Cristillo, Anthony D.; Bristow, Claire C.;... More
The Klapperich Lab manuscript describing an integrated paperfluidic diagnostic device to detect high risk HPV at the point of care was on the most downloaded list for Lab on Chip in 2016. The paper describes the culminating work for Dr. Natalia Rodriguez' Ph.D. thesis. This technology forms the basis for... More
Check out our new paper comparing different porous substrates for in situ nucleic acid amplification. Polyethersulfone improves isothermal nucleic acid amplification compared to current paper-based diagnostics. Linnes JC, Rodriguez NM, Liu L, Klapperich CM, Biomed Microdevices. 2016 Apr;18(2):30. doi: 10.1007/s10544-016-0057-z. PMID: 26906904 Free PMC Article
A fully integrated paperfluidic molecular diagnostic chip for the extraction, amplification, and detection of nucleic acids from clinical samples Abstract Paper diagnostics have successfully been employed to detect the presence of antigens or small molecules in clinical samples through immunoassays; however, the detection of many disease targets relies on the much higher... More
New CFTCC publication out this week at PLoS ONE. Open access links: Kim CS, Vanture S, Cho M, Klapperich CM, Wang C, et al. (2016), “Awareness, Interest, and Preferences of Primary Care Providers in Using Point-of-Care Cancer Screening Technology,” PLoS ONE 11(1): e0145215. doi: 10.1371/journal.pone.0145215 Abstract Well-developed point-of-care (POC) cancer screening tools have the potential to provide better cancer care to patients in both... More
Check out Dr. Klapperich's commentary on Radio Boston. https://radioboston.wbur.org/2015/10/19/theranos-biotech ....and the op ed on the Commonhealth blog! http://commonhealth.wbur.org/2015/10/theranos-quick-diagnoses
The Klapperich Lab Senior Project Team won second place at the North East Bioengineering Conference last week. Congratulations to Courtney, Nelson, Gil and Danielle!
Colorimetric Detection of Azidothymidine Using an Alkyne-Modified Dextran Substrate George W. Pratt , Andy Fan , and Catherine M. Klapperich * College of Engineering, Boston University, Boston, Massachusetts 02215, United States ABSTRACT Monitoring the adherence of patients taking highly active antiretroviral therapy (HAART) is a key step in treating an HIV infection, especially in resource-limited settings in the developing world. For... More
Dr. Klapperich is the new Associate Dean for Research and Technology Development in the College of Engineering. See the news story for more information about her new role.
The College announced Dr. Klapperich's promotion this week. Check out the 21 new Full Professors at Charles River Campus!