News
Women’s Health in Engineering Initiative May Meetup
RSVP for Dinner
March Student Meeting of the COE Women’s Health in Engineering Initiative
Women’s Health in Engineering Event 2/15/24
Graduate students, please join us.
Relationship Between Nostril Viral Loads and Symptoms in COVID-19
Comparison of anterior nares CT values in asymptomatic and symptomatic individuals diagnosed with SARS-CoV-2 in a university screening program Abstract (from PLoS ONE, July 13, 2022) At our university based high throughput screening program, we test all members of our community weekly using RT-qPCR. RT-qPCR cycle threshold (CT) values are inversely proportional to... More
Nature Communications Paper on a New Progesterone Biosensor is Out!
A progesterone biosensor derived from microbial screening Chloé Grazon, R C. Baer, Uroš Kuzmanović,Thuy Nguyen, Mingfu Chen, Marjon Zamani, Margaret Chern, Patricia Aquino, Xiaoman Zhang, Sébastien Lecommandoux, Andy Fan, Mario Cabodi, Catherine Klapperich, Mark W. Grinstaff, Allison M. Dennis & James E. Galagan Nature Communications volume 11, Article number: 1276 (2020) Abstract Bacteria are an enormous and largely untapped reservoir of biosensing proteins. We describe an approach to identify and isolate bacterial allosteric transcription... More
RNA Extraction Methods Archive
Protocols, papers, and links for nucleic acid extraction from human samples without using a "kit." You can do it! And we can help. Check it out. https://www.bu.edu/klapperich/rna-and-dna-extraction-protocols-and-papers/
New Molecular Test for Malaria Paper Online!
Online article! Work with our partners describes a new way to mine the malaria genome to create primer sets that are 100x more sensitive at detecting malaria when compared to Pf18S rRNA primers. The new assay was validated with human samples. Srinivasa Raju, L., Kamath, S., Chandana Shetty, M., Satpathi, S., More
Urine Test Strips for PrEP Adherence Paper now Online
George's tenofovir drug adherence monitoring paper is out. Looking forward to ongoing work in the clinic! Full text at the link: https://www.sciencedirect.com/science/article/pii/S000326701830254X
New Article in Sexually Transmitted Diseases Journal – POC Diagnostics Now and in the Future
A new discussion of clinical needs and current advancements in point of care technologies for sexually transmitted infections. Click on the link for the open access version of the paper. Point-of-Care Sexually Transmitted Infection Diagnostics: Proceedings of the STAR Sexually Transmitted Infection—Clinical Trial Group Programmatic Meeting Cristillo, Anthony D.; Bristow, Claire C.;... More
Klapperich Lab Paper Makes Most Downloaded List for LOC in 2016!
The Klapperich Lab manuscript describing an integrated paperfluidic diagnostic device to detect high risk HPV at the point of care was on the most downloaded list for Lab on Chip in 2016. The paper describes the culminating work for Dr. Natalia Rodriguez’ Ph.D. thesis. This technology forms the basis for the formation... More