HomeBack to Data directory 

Microarray Experiment - Global analysis of gene expression patterns during disuse atrophy in rat skeletal muscle

Gene expression analysis of rat soleus muscles using Affymetrix GeneChips after 1, 4, 7 and 14 days of hindlimb unloading. Of the 8,799 probe sets on the U34A GeneChip, 426 were significantly changed by at least 2-fold with hindlimb unloading.

The following table is ordered by gene name.

probe_id - Affymetrix probe set ID (based on the GenBank accession sequence the probe set was developed from)

k_cluster - Cluster each gene was associated with after using a k-means clustering algorithm to divide genes into groups based on similarity in expression over the timecourse of unloading.

day01-day14 - Fold change at each time point calcualted as described.

function - The functional categories used were derived from Silicon Genetics and NCBI annotation records. Annotations were obtained for each gene from LocusLink and Unigene based on the GenBank sequences from which probes were derived. In the cases where rat functional information was incomplete, function was inferred based on curated homologs in mouse and/or human (HomoloGene).

possible_pathways - Notes based on the literature and functional annotations as to involvment in signaling pathways or cellular mechanisms

 

Probe_ID gene_name day1 day4 day7 day14 function possible_pathways notes
M59861_at 10-formyltetrahydrofolate dehydrogenase   1.1 3.3 2.8 2.2 metabolism; miscellaneous    
rc_AA817846_at 3-hydroxybutyrate dehydrogenase -1.1 -2.2 -1.8 -3.1 protein turnover; metabolism    
rc_AA892799_s_at 3-phosphoglycerate dehydrogenase, ESTs, (rat) 2.6 2.1 2.2 1.6 protein turnover; metabolism; protein; amino acid    
U70825_at 5-oxoprolinase (ATP-hydrolysing) 1.2 1.6 1.6 2.0 protein turnover; metabolism; protein; amino acid    
S50879_g_at Acetylcholinesterase T subunit 1.7 1.6 1.6 2.3 contraction; unclassified; membrane depolarization    
S50879_at Acetylcholinesterase T subunit 1.2 1.1 2.2 1.5 contraction; unclassified; membrane depolarization    
X80130cds_f_at Actin, alpha- (cardiac) -1.5 -2.2 -1.3 -1.0 contraction; embryonic; cytoskeleton/sarcomere    
rc_AA866452_s_at Actin, alpha- (cardiac) -2.0 -3.1 -1.2 1.4 contraction; embryonic; cytoskeleton/sarcomere    
X80130cds_i_at Actin, alpha- (cardiac) -1.8 -2.8 -1.1 1.5 contraction; embryonic; cytoskeleton/sarcomere    
rc_AA800206_at Actinin 1, alpha EST (rat) -1.0 -2.1 -2.2 -1.7 contraction; unclassified; cytoskeleton/sarcomere    
L10640_s_at Activin type IIB receptor 3.1 2.5 5.1 5.8 regulatory; growth/proliferation; growth factor activity; TGF-beta transmembrane receptor; secreted growth factor activity; SMAD; TGFbeta receptor signaling pathway  
M98819mRNA_s_at Adenosine monophosphate deaminase 1 1.1 1.6 2.0 1.9 protein turnover; metabolism; protein; amino acid    
rc_AI176052_at Adenylate kinase 3 1.2 2.2 1.9 1.9 metabolism; carbohydrate; glycolytic    
X59864mRNA_at Adult skeletal muscle gene 15; H19 -1.0 -2.1 -2.1 -1.4 regulatory; growth/proliferation; proliferation IGF; development; translation regulator; 4E-BP1; p70(S6k) The results showed that the well-documented early effects of clenbuterol on protein metabolism were preceded by elevated levels of IGF-II and H19 transcripts together with increased phosphorylation of eukaryotic initiation factor (eIF)4E binding protein-1
X59864mRNA_g_at Adult skeletal muscle gene 15; H19 -1.0 -2.3 -2.3 -1.5 regulatory; growth/proliferation; proliferation IGF; development; translation regulator; 4E-BP1; p70(S6k) The results showed that the well-documented early effects of clenbuterol on protein metabolism were preceded by elevated levels of IGF-II and H19 transcripts together with increased phosphorylation of eukaryotic initiation factor (eIF)4E binding protein-1
AF001898_at Aldehyde dehydrogenase 1 1.3 1.4 2.2 1.5 metabolism; aldehyde    
rc_AI172017_at aldehyde dehydrogenase 2 1.4 2.0 1.9 1.3 metabolism; aldehyde    
M12919mRNA#2_at Aldolase A, fructose-bisphosphate -1.0 1.2 1.9 2.4 metabolism; carbohydrate; glycolytic    
rc_AA924326_s_at Aldolase A, fructose-bisphosphate 1.0 1.4 2.3 2.8 metabolism; carbohydrate; glycolytic    
X60351cds_s_at Alpha B-crystallin -1.4 -6.6 -5.9 -4.2 protein turnover; protein folding    
AF051895_at Annexin 5 -1.2 -2.2 -2.1 -2.2 regulatory; growth/proliferation; proliferation apoptosis; calcium signaling  
D42137exon_s_at Annexin 5 -1.0 -2.5 -2.4 -2.1 regulatory; growth/proliferation; proliferation apoptosis; calcium signaling  
J03627_at Annexin II ligand, calpactin I (S100a10) -1.2 -1.8 -2.0 -2.4 regulatory; signal transduction calcium signaling; cell cycle; differentiation  
U49062_at Antigen CD24 3.7 5.7 11.0 13.0 stress; immune; antigen    
U49062_g_at Antigen CD24 2.5 2.8 2.7 1.8 stress; immune; antigen    
rc_AA818025_g_at Antigen CD59 1.6 2.0 2.2 2.7 stress; immune; antigen    
rc_AA818025_at Antigen CD59 1.4 1.8 1.8 2.2 stress; immune; antigen    
S76779_s_at apolipoprotein E 1.6 1.9 2.1 1.9 metabolism; lipid; uptake and transport    
U47315_s_at Apoptosis-regulating basic protein 1.2 -2.1 -1.9 -2.0 regulatory; growth/proliferation; proliferation; apoptosis apoptosis;  
D44495_s_at apurinic/apyrimidinic endonuclease 1 2.1 1.9 1.4 1.3 regulatory; transcription cAMP responsive; DNA repair; stress or injury  
U14007_at Aquaporin 4 -1.1 1.4 3.4 3.3 ion transport; sodium/phosphate symporter water transport  
AB000507_at Aquaporin 7 -1.3 -2.8 -1.9 -3.0 ion transport; sodium/phosphate symporter water transport  
J05210_g_at ATP citrate lyase 1.2 1.3 1.2 2.1 metabolism; tricarboxylic acid cycle    
D13123_s_at ATP synthase, H+ transporting, mitochondrial F0 complex, subunit 9 -1.1 -1.7 -2.2 -1.8 metabolism; respiratory chain    
rc_AI177026_at ATPase Na K transporting alpha 2 1.6 2.5 2.7 1.9 ion transport; sodium/potassium    
rc_AI112173_at ATPase Na K transporting beta 1 -1.2 -2.2 -1.6 -1.2 ion transport; sodium/potassium    
rc_AI230614_s_at ATPase Na K transporting beta 1 -1.0 -2.1 -1.4 -1.4 ion transport; sodium/potassium    
M99223_at ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 1.2 2.9 3.8 5.9 contraction; fast; membrane depolarization    
X96394_at ATP-binding cassette, sub-family C ( CFTR/MRP), member 1a 5.4 2.6 3.3 3.1 stress; oxidative/toxic    
S48813_s_at Beta-adrenergic receptor kinase -1.1 1.6 3.7 6.8 regulatory; signal transduction stress or injury; GTP signaling  
AF056034_s_at b-Nexilin 1.0 -2.0 -2.1 -1.2 regulatory; adhesion adhesion  
rc_AA799423_at b-Nexilin -1.0 -1.9 -2.1 -1.4 regulatory; adhesion adhesion  
J02827_at Branched chain alpha-ketoacid dehydrogenase subunit E1 alpha 1.6 2.1 2.1 1.8 protein turnover; metabolism; protein; amino acid    
U35774_at Branched chain aminotransferase 1, cytosolic -1.5 -2.3 -1.4 -1.0 protein turnover; metabolism; protein; amino acid    
rc_AA891614_at Calcium channel, voltage gated (Tpcn1) 1.2 1.7 1.1 2.4 contraction; membrane depolarization    
Y09453cds_at Calcium channel, voltage-dependent, gamma subunit 1 1.2 1.9 1.9 2.3 contraction; fast; membrane depolarization    
M16112_at Calcium/calmodulin-dependent protein kinase II beta 1.8 -1.5 -1.5 -2.8 regulatory; signal transduction calcium signaling  
S71570_s_at Calmodulin-dependent protein kinase 2 gamma 2.0 2.1 2.0 1.7 regulatory; signal transduction calcium signaling  
X56729mRNA_at Calpastatin/CANP inhibitor 2.8 4.0 1.3 4.5 protein turnover; proteolysis; protease inhibitor; calpain    
U33287_at Calsequestrin 2 1.1 -2.7 -4.1 -3.0 contraction; slow; cytoskeleton/sarcomere    
U04835_at cAMP responsive element modulator (CREM) -11.2 -2.5 -2.0 -1.4 regulatory; transcription cAMP responsive; translation regulator  
S66024_at cAMP responsive element modulator (CREM) -8.6 -6.6 -1.5 -2.7 regulatory; transcription cAMP responsive; translation regulator  
AF037072_at Carbonic anhydrase 3 -1.1 -4.9 -8.8 -7.7 metabolism; miscellaneous    
X65296cds_s_at carboxylesterase 1.7 9.6 4.0 3.2 metabolism; lipid    
L46791_at carboxylesterase 3 7.6 10.6 1.0 2.6 metabolism; lipid    
U50736_s_at Cardiac ankyrin repeat protein (Carp) -2.5 -1.7 -2.5 -6.7 regulatory; transcription cytokine signaling; differentiation; development  
D90404_at Cathepsin C 1.8 2.1 2.4 3.0 protein turnover; proteolysis; protease; lysosomal    
D90404_g_at Cathepsin C (dipeptidyl peptidase I) -1.3 1.1 5.6 4.0 protein turnover; proteolysis; protease; lysosomal    
X54467_at Cathepsin D (preprocathepsin) 1.2 2.3 1.9 1.5 protein turnover; proteolysis; protease; lysosomal    
S85184_at Cathepsin L 1.1 3.3 5.1 1.6 protein turnover; proteolysis; protease; lysosomal    
rc_AI176595_s_at Cathepsin L 1.4 3.1 4.6 2.2 protein turnover; proteolysis; protease; lysosomal    
S85184_g_at Cathepsin L proenzyme 1.2 1.7 2.6 1.4 protein turnover; proteolysis; protease; lysosomal    
rc_AI014091_at Cbp/p300-interacting transactivator 2; Mrg1 2.8 2.0 2.6 1.3 regulatory; transcription development; apoptosis; myogenesis  
rc_AA900476_g_at Cbp/p300-interacting transactivator 2; Mrg1 1.7 1.5 2.2 1.5 regulatory; transcription development; apoptosis; myogenesis  
rc_AA900476_at Cbp/p300-interacting transactivator 2; Mrg1 5.2 2.2 6.6 3.4 regulatory; transcription development; apoptosis; myogenesis  
AB000199_at CCA2 protein -1.8 -2.1 -2.7 -2.6 unknown    
D26439_at CD1D antigen 2.0 1.7 1.3 1.3 stress; immune; antigen    
X13044_g_at CD74 antigen (invariant polpypeptide of major histocompatibility class II antigen-associated) -1.1 1.3 2.1 1.6 stress; oxidative/toxic    
X13044_at CD74 antigen (invariant polpypeptide of major histocompatibility class II antigen-associated) 1.0 1.3 2.3 1.3 stress; immune; antigen    
X94351_at CDC-like kinase 3 2.3 1.9 1.6 1.5 regulatory; signal transduction SR protein localization; mRNA splicing The prototype, murine Clk1 (mClk1), is a nuclear dual-specificity kinase that can interact with, and cause the nuclear redistribution of, SR proteins.
rc_AA860015_at cDNA clone 617608 -1.2 -2.1 -1.1 -1.1 unknown    
rc_AA858588_g_at cDNA clone 864365 1.6 2.0 2.5 1.6 unknown    
rc_AA817854_s_at Ceruloplasmin (ferroxidase) 1.1 1.4 3.7 2.7 stress; oxidative/toxic    
L33869_at Ceruloplasmin (ferroxidase) -1.4 1.3 2.0 2.5 stress; oxidative/toxic    
X62894_at Chloride channel 1 (skeletal muscle) 2.5 1.3 3.1 4.2 contraction; unclassified; membrane depolarization    
AF072892_s_at Chondroitin sulfate proteoglycan 2 -2.1 -1.8 -1.7 -1.3 regulatory; growth/proliferation; ECM    
rc_AI175959_at c-Jun, EST (human) 1.3 1.7 3.1 2.2 regulatory; transcription apoptosis; SMAD; AP1; NFkB; ferritin  
X53054_at Class II MHC RT1.D(n) beta chain precursor 1.0 1.2 10.8 4.2 stress; immune; antigen    
X53054_g_at Class II MHC RT1.D(n) beta chain precursor -1.1 1.1 2.4 1.3 stress; immune; antigen    
AB000362_at Cold inducible RNA-binding protein 2.7 3.4 2.9 2.7 regulatory; mRNA processing RNA stability; shock  
rc_AI231472_s_at Collagen, alpha 1 type I 1.1 -1.4 -1.5 -2.2 ECM structrual/regulator    
U75405UTR#1_f_at Collagen, alpha 1 type I -1.0 -1.1 -1.6 -2.0 ECM structrual/regulator    
rc_AI179399_at Collagen, alpha 2 type V -1.1 -1.2 -1.5 -2.0 ECM structrual/regulator    
U42719_at Complement component 4 1.9 2.6 1.3 3.4 protein turnover; proteolysis; protease    
M31725_at Contactin 2 2.2 1.8 1.8 -1.0 regulatory; adhesion development; adhesion; membrane targeting  
M55534mRNA_s_at Crystallin, alpha polypeptide 2 -1.2 -6.5 -6.2 -4.7 protein turnover; protein folding    
U21101_at cyclic GMP stimulated phosphodiesterase 1.3 2.9 2.4 3.1 regulatory; signal transduction cAMP regulator;  
U24174_at Cyclin-dependent kinase inhibitor 1A (P21) 1.9 2.0 14.2 2.5 regulatory; growth/proliferation; proliferation; cell cycle arrest cytokine signaling; G1 cyclin/CDK complex inhibtion; p53; AKT/PKB induced; apoptosis; differentiation; development; cell cycle arrest; tumor suppressor; oncogenesis  
L41275cds_s_at Cyclin-dependent kinase inhibitor 1A (P21) 1.3 2.1 19.4 4.9 regulatory; growth/proliferation; proliferation; cell cycle arrest cytokine signaling; G1 cyclin/CDK complex inhibtion; p53; AKT/PKB induced; apoptosis; differentiation; development; cell cycle arrest; tumor suppressor; oncogenesis  
rc_AI231292_g_at Cystatin C 1.5 1.9 2.5 2.2 protein turnover; proteolysis; protease inhibitor; cathepsin    
rc_AI231292_at Cystatin C 1.4 2.1 3.2 3.1 protein turnover; proteolysis; protease inhibitor; cathepsin    
S61960_s_at Cysteine conjugate beta-lyase 2.2 2.4 1.6 1.2 protein turnover; metabolism; protein; amino acid    
rc_AA942685_at Cysteine dioxygenase 1 1.4 3.2 3.1 1.8 protein turnover; metabolism; protein; amino acid    
Y12517cds_at Cytochrome b5, outer mitochondrial membrane isoform 3.1 1.1 1.2 1.4 metabolism; respiratory    
X64827cds_s_at Cytochrome C oxidase subunit VIIIh (heart/muscle) 1.2 -1.4 -1.6 -2.6 metabolism; respiratory    
AF055884_s_at DEAF-1 related transcriptional regulator (NUDR) -1.5 1.3 1.8 2.2 regulatory; transcription    
rc_AI010581_at Diazepam binding inhibitor -1.0 -2.0 -3.0 -2.0 protein turnover; proteolysis; protease inhibitor    
rc_AA799732_at DiGeorge syndrome critical region gene 6; EST (mouse) 1.4 2.3 1.4 1.4 regulatory; growth/proliferation; ECM    
rc_AA891107_at Diphosphoinositol polyphosphate phosphohydolase t2 -1.3 -2.0 -1.6 -2.3 regulatory; signaling intracellular trafficking The turnover of the "high energy" diphosphoinositol polyphosphates by Ca(2+)- and cyclic nucleotide-modulated enzymes is considered a regulatory, molecular switching activity. Target processes may include intracellular trafficking.
U14950_at Discs, large homolog 1 (Drosophila) 1.9 2.2 2.5 1.6 regulatory; cytoskeletal regulator PDZ; SH3; cytoskeletal organization; tumor supressor  
L32591mRNA_g_at DNA-damage-inducible transcript 1 2.1 2.9 1.8 1.7 regulatory; growth/proliferation; proliferation; cell cycle arrest DNA repair; stress or injury; cell cycle arrest; p38/JNK; translation regulator; G2-M arrest; apoptosis The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms.
L32591mRNA_at DNA-damage-inducible transcript 1 1.4 4.1 1.9 2.3 regulatory; growth/proliferation; proliferation; cell cycle arrest DNA repair; stress or injury; cell cycle arrest; p38/JNK; translation regulator; G2-M arrest; apoptosis The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms.
AA848268_at DnaJ Homolog 5 -1.0 -1.9 -2.2 -1.9 protein turnover; protein folding    
rc_AA891542_at DnaJ Homolog 5 -2.3 -1.7 -1.5 -1.6 protein turnover; protein folding    
rc_AI009806_at Dynein, cytoplasmic, light chain 1 -2.1 -2.0 -1.9 -1.3 cytoskeleton/sarcomere; structural    
rc_AI233219_at Endothelial cell-specific molecule 1; Pineal specific PG25 protein -1.5 -2.8 -1.7 -1.8 regulatory; growth/proliferation; ECM IGF; cytokine signaling; tumor supressor; secreted growth factor activity insulin-like growth factor binding activity; secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues
Z54212_at Epithelial membrane protein 1 -1.2 -1.7 -1.8 -2.0 regulatory; growth/proliferation; proliferation; oncogenesis/tumor supressor secreted growth factor activity; cell proliferation; development; oncogenesis; differentiation  
rc_AA924925_at ER transmembrane protein Dri 42 1.0 1.0 2.0 2.1 regulatory; signal transduction    
rc_AI639510_at EST, clone rx02430, 3'end 1.2 1.7 1.4 2.2 unknown    
rc_AA800168_at EST, clone UI-R-C2p-rd-d-02-0-UI, 3'end 1.1 1.2 2.1 1.3 unknown    
rc_AA800216_at EST189713 -1.3 -2.2 -2.7 -1.6 unknown    
rc_AA800750_f_at EST190247 1.0 -1.5 -2.1 -2.7 unknown    
rc_AA893871_at EST197674 Normalized rat placenta, Bento ESTs, Soares Rattus sp. cDNA clone RPLAM87 3' end, MRNA sequence 1.2 -1.1 1.6 2.1 unknown    
rc_AA800218_at ESTs 2.6 2.3 2.4 1.7 unknown    
rc_AA799971_g_at ESTs 1.1 1.4 1.9 2.0 unknown    
rc_AA892897_at ESTs 1.1 -1.4 -1.1 -2.5 unknown    
rc_AA799971_at ESTs 1.1 1.2 1.4 2.1 unknown    
rc_AA799964_at ESTs 1.4 1.7 2.0 1.5 unknown    
rc_AA866259_at Ests 2.3 1.1 1.3 1.3 unknown    
rc_AI639170_at ESTs 2.2 1.1 1.8 2.1 unknown    
rc_AI639238_at ESTs 1.9 1.9 2.2 1.9 unknown    
rc_AI639499_s_at ESTs 1.4 2.4 2.9 2.0 unknown    
rc_AA799762_g_at ESTs 1.6 1.1 2.2 1.2 unknown    
rc_AA800197_at ESTs 1.3 1.6 2.6 1.0 unknown    
rc_AA891054_at ESTs 1.3 2.2 2.5 3.1 unknown    
rc_AA893208_at ESTs 2.3 -1.1 1.5 1.1 unknown    
rc_AI639294_at ESTs 1.1 2.1 2.1 1.2 unknown    
rc_AA892280_at ESTs 2.8 2.1 2.4 1.6 unknown    
X07551cds_s_at Ests 1.1 1.5 2.0 1.9 uknown    
rc_AA875390_at ESTs -3.4 6.4 4.0 -2.2 unknown    
rc_AA892549_at ESTs 2.3 1.1 1.9 3.1 unknown    
rc_AA859536_at ESTs -1.1 -1.6 -1.5 -2.2 unknown    
rc_AI231778_at ESTs 2.6 1.8 1.8 1.8 unknown    
rc_AA799467_at ESTs 1.8 2.3 1.9 1.8 unknown    
rc_AA892353_at Ests -1.3 1.7 2.2 1.6 unknown    
rc_AA799457_at ESTs -1.7 -2.1 -2.1 -2.1 unknown    
rc_AA799570_at ESTs -1.2 -2.0 -2.5 -2.1 unknown    
rc_AI236601_at ESTs -1.3 -2.0 -1.8 -2.4 unknown    
rc_AA893280_at ESTs -1.0 -1.5 -2.0 -2.4 unknown    
rc_AA894304_at ESTs 1.4 1.7 1.9 2.5 unknown    
rc_AI639035_at ESTs 3.2 1.3 1.1 2.4 unknown    
rc_AA894092_at ESTs 1.1 -2.5 -3.6 -5.8 unknown    
rc_AA799666_g_at ESTs -1.0 -2.3 -2.0 -1.7 unknown    
rc_AI639163_at ESTs -1.4 -1.5 -1.7 -2.3 unknown    
rc_H31964_at ESTs 1.4 1.1 1.2 2.0 unknown    
rc_AA892500_at ESTs 1.3 1.6 2.6 1.7 unknown    
rc_AA875132_at ESTs -1.1 1.7 3.1 6.8 unknown    
rc_AI233365_at ESTs 2.0 1.4 1.7 1.8 unknown    
rc_AA875032_at ESTs 1.3 1.8 2.1 1.1 unknown    
rc_AA891818_at ESTs -1.4 -2.1 -1.8 -2.1 unknown    
rc_AA892531_at ESTs 1.2 1.4 2.1 2.0 unknown    
rc_AA858607_at ESTs 1.5 1.4 2.6 2.1 unknown    
rc_AA893043_at ESTs 1.0 -1.4 -1.5 -2.6 unknown    
rc_AA892325_at ESTs, Highly similar to choline/ethanolaminephosphotransferase [Homo sapiens] [H.sapiens] 1.6 -1.0 4.0 1.4 unknown    
rc_AI639088_s_at ESTs, similar to RNA imprinted and accumulated in nucleus (mouse) -1.3 -4.1 -3.1 -3.0 unknown    
rc_AA818726_at ESTs, Weakly similar to CYPM_RAT Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor (PPIase) (Rotamase) (Cyclophilin F) [R.norvegicus] 1.3 2.2 1.6 1.6 unknown    
rc_AA800808_at ESTs, Weakly similar to S12207 hypothetical protein (B2 element) - mouse [M.musculus] 1.7 2.4 1.4 -1.7 unknown    
U59241_at E-Tropomodulin 1.4 2.9 4.7 4.1 contraction; unclassified; cytoskeleton/sarcomere    
X96426_at eukaryotic elongation factor 2 kinase 1.7 1.3 2.3 2.3 protein turnover; translation; inhibitor IGF  
rc_AI059692_s_at eukaryotic elongation factor 2 kinase 1.7 2.3 2.7 2.1 protein turnover; translation; inhibitor IGF  
U05014_at eukaryotic translation initiation factor 4E binding protein 1 2.2 2.7 6.4 1.8 protein turnover; translation; inhibitor IGF  
U05014_g_at eukaryotic translation initiation factor 4E binding protein 1 1.4 2.3 3.8 1.7 protein turnover; translation; inhibitor IGF  
J02773_at Fatty acid binding protein, heart -1.3 -4.3 -3.2 -5.1 metabolism; lipid; uptake and transport    
X13527cds_s_at fatty acid synthase 1.5 1.1 -1.2 2.1 metabolism; lipid; FA oxidation    
rc_AI236284_s_at Fatty acid-Coenzyme A ligase, long chain 4 1.6 2.2 3.5 1.8 metabolism; lipid biosynthesis    
D85189_at Fatty acid-Coenzyme A ligase, long chain 4 -1.0 2.3 2.3 1.6 metabolism; lipid biosynthesis    
X14323cds_g_at Fc receptor, IgG, alpha chain transporter 1.7 2.2 2.4 2.3 stress; immune; antigen    
X56551cds_at fibroblast growth factor 7 2.3 1.8 1.7 3.2 regulatory; growth/proliferation; secreted growth factor secreted growth factor activity; positive regulation of cell proliferation; differentiation  
rc_AA799773_g_at Filamin, gamma-, EST (human) -1.6 -2.2 -1.4 -1.5 regulatory; cytoskeletal regulator cytoskeletal organization  
rc_AA799773_at Filamin, gamma-, EST (human) -1.7 -2.3 -1.3 -1.2 regulatory; cytoskeletal regulator cytoskeletal organization  
rc_AA858520_g_at Follistatin 1.4 2.4 3.7 2.8 regulatory; growth/proliferation;growth factor; TGF-beta; secreted growth factor activity; SMAD; TGFbeta receptor signaling pathway  
rc_AA849769_g_at Follistatin related protein precursor -1.3 -1.7 -2.2 -1.5 regulatory; growth/proliferation;growth factor; TGF-beta; secreted growth factor activity; SMAD; TGFbeta receptor signaling pathway  
rc_H31144_g_at formin 2; EST (mouse) 1.5 1.7 2.1 2.1 cytoskeleton/sarcomere; structural    
rc_AA891527_at Four and a half LIM domains 2 (Slim3) -5.9 -3.5 -3.7 -4.6 regulatory; adhesion differentiation; NFKB; IGF; adhesion; LIM; myogenesis  
AJ005046_g_at Fructose bisphosphatase 2, muscle 1.2 -1.0 2.0 6.4 metabolism; carbohydrate; glycolytic    
X15580complete_seq_s_at fructose-2,6-bisphosphatase 1 2.5 3.8 3.7 5.3 metabolism; carbohydrate; glycolytic    
J04197_i_at fructose-2,6-bisphosphatase 1 1.9 1.8 1.2 3.2 metabolism; carbohydrate; glycolytic    
L26292_g_at FSH-regulated 1.2 -3.7 -2.5 -2.1 regulatory; growth/proliferation; growth factor activity    
M77694_at Fumarylacetoacetate hydrolase 2.0 1.7 2.0 2.1 protein turnover; metabolism; protein; amino acid    
AB016161cds_r_at gamma-aminobutyric acid (GABA) B receptor, 1 1.2 1.5 2.4 1.5 regulatory; signal transduction adenylate cyclase activity; gamma-amino butyric acid signaling pathway; synaptic; metabotropic glutamate receptor signaling pathway  
AF080468_g_at Glucose-6-phosphatase, transport protein 1 1.8 2.6 1.8 1.6 metabolism; carbohydrate; glycolytic    
AF080468_at Glucose-6-phosphatase, transport protein 1 1.5 2.3 1.4 1.9 metabolism; carbohydrate; glycolytic    
S63521_i_at Glucose-regulated protein GRP78 -1.6 -8.8 -3.3 -4.5 protein turnover; protein folding    
M90518_at Glutamate receptor, metabotropic 4 -1.4 -1.6 -2.3 -1.0 regulatory; signal transduction cAMP responsive; G-protein coupled receptor protein signaling pathway; synaptic transmission; metabotropic glutamate, GABA-B-like receptor activity; negative regulation of adenylate cyclase activity Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities
M91652complete_seq_g_at Glutamine synthetase glutamate-ammonia ligase 1.3 3.4 6.9 3.5 protein turnover; metabolism; protein; amino acid    
rc_AA852004_s_at Glutamine synthetase glutamate-ammonia ligase 1.1 3.4 7.2 3.7 protein turnover; metabolism; protein; amino acid    
M91652complete_seq_at Glutamine synthetase glutamate-ammonia ligase -1.1 4.2 9.6 4.4 protein turnover; metabolism; protein; amino acid    
rc_AI232783_s_at Glutamine synthetase glutamate-ammonia ligase 1.0 2.1 4.9 3.3 protein turnover; metabolism; protein; amino acid    
X07365_s_at Glutathione peroxidase 1 -1.4 -4.0 -3.9 -2.0 stress; oxidative/toxic    
X12367cds_s_at Glutathione peroxidase 1 -1.3 -3.0 -3.5 -1.9 stress; oxidative/toxic    
D00680_at glutathione peroxidase precursor, plasma 1.2 1.6 1.9 2.2 stress; oxidative/toxic    
E01415cds_s_at Glutathione-S-transferase 1.3 2.6 1.9 1.5 stress; oxidative/toxic    
rc_AA892234_at Glutathione-S-transferase 3, EST (human) -1.1 -2.0 -3.8 -2.3 stress; oxidative/toxic    
U86635_at Glutathione-S-transferase mu 5 1.6 2.7 3.0 2.8 stress; oxidative/toxic    
U86635_g_at Glutathione-S-transferase mu 5 1.7 2.3 2.7 2.6 stress; oxidative/toxic    
K01932_f_at Glutathione-S-transferase, alpha type (Ya) 1.7 4.4 3.4 2.0 stress; oxidative/toxic    
X78848cds_f_at Glutathione-S-transferase, alpha type (Ya) 2.0 2.7 3.7 2.5 stress; oxidative/toxic    
S72505_f_at Glutathione-S-transferase, alpha type (Ya) 3.2 6.2 6.6 2.9 stress; oxidative/toxic    
J03914cds_s_at glutathione-S-transferase, mu type 2 (Yb2) 1.5 3.2 5.3 5.6 stress; oxidative/toxic    
X04229cds_s_at glutathione-S-transferase, mu type 2 (Yb2) 1.7 2.7 2.9 2.1 stress; oxidative/toxic    
J02592_s_at glutathione-S-transferase, mu type 2 (Yb2) -1.1 3.1 3.5 6.6 stress; oxidative/toxic    
H32189_s_at glutathione-S-transferase, mu type 2 (Yb2) 1.0 2.0 2.2 1.9 stress; oxidative/toxic    
U36772_at Glycerol-3-phosphate acyltransferase 1.3 1.6 2.3 1.5 metabolism; lipid; thermogenesis    
U36773_g_at glycerol-3-phosphate acyltransferase, mitochondrial 1.7 1.4 2.2 -1.2 metabolism; lipid; thermogenesis    
X78593_at glycerol-3-phosphate dehydrogenase 2 2.0 2.9 1.4 1.4 metabolism; carbohydrate; glycolytic    
U83880UTR#1_at glycerol-3-phosphate dehydrogenase 2 1.6 2.0 5.0 4.9 metabolism; carbohydrate; glycolytic    
L10669_g_at Glycogen phosphorylase muscle isozyme 1.5 2.4 3.3 2.9 metabolism; carbohydrate; glycogenolysis    
L10669_at Glycogen phosphorylase muscle isozyme 1.4 2.2 2.9 2.6 metabolism; carbohydrate; glycogenolysis    
L10326_at GNAS complex locus -1.0 1.5 2.2 1.6 regulatory; vesicle transport GTP signaling; intracellular trafficking; adenylate cyclase activation  
U77829mRNA_i_at growth arrest specific 5 1.5 2.1 1.5 1.2 regulatory; growth/proliferation; proliferation; cell cycle arrest cell cycle arrest; differentiation; development  
U77829mRNA_s_at growth arrest specific 5 1.5 2.7 1.5 -1.0 regulatory; growth/proliferation; proliferation; cell cycle arrest cell cycle arrest; differentiation; development  
AF076619_at Growth factor receptor bound protein 14 1.3 2.0 1.8 1.4 regulatory; growth/proliferation; growth factor activity SH3; SH2; neuropeptide signaling pathway; secreted growth factor activity  
S49003_s_at Growth hormone receptor, short isoform -1.2 6.5 1.4 3.9 regulatory; growth/proliferation; growth factor activity secreted growth factor activity  
D13417_g_at Hairy-related and enhancer of split 1 1.8 2.6 2.0 1.7 regulatory; transcription adhesion; development; Ebox; neurogenesis; Notch signaling; myogenesis  
D29960_at Heat shock 20-kDa protein -1.3 -3.8 -3.4 -2.7 protein turnover; protein folding    
rc_AI103838_g_at Heat shock 20-kDa protein -1.5 -4.4 -3.3 -2.6 protein turnover; protein folding    
M86389cds_s_at Heat shock 27kD protein 1 -2.1 -1.3 1.2 -1.9 protein turnover; protein folding    
AF077354_g_at heat shock 70 kDa protein 4 -1.2 -1.9 -1.9 -2.3 protein turnover; protein folding    
M14050_s_at heat shock 70kD protein 5 -2.1 -2.7 -1.8 -2.2 protein turnover; protein folding    
L16764_s_at Heat shock protein 70 -3.4 -3.6 -2.8 -2.1 protein turnover; protein folding    
Z75029_s_at Heat shock protein 70 -5.0 -3.2 -1.9 -1.3 protein turnover; protein folding    
Z27118cds_s_at Heat shock protein 70 -6.1 -3.2 -2.3 -2.0 protein turnover; protein folding    
rc_AA818604_s_at Heat shock protein 70 -3.1 -2.8 -2.4 -1.9 protein turnover; protein folding    
AA848563_s_at Heat shock protein 70 -4.0 -5.6 -12.8 -7.4 protein turnover; protein folding    
rc_AI176546_at Heat shock protein 90 beta -3.0 -2.1 -2.3 -2.8 protein turnover; protein folding    
AA108277_at Heat shock protein E71, 5' similar to hsp-E7I -1.7 -2.2 -1.9 -2.7 protein turnover; protein folding    
rc_AA875531_s_at Heat shock protein, 60 kDa 1.1 -1.3 -1.9 -2.1 protein turnover; protein folding    
S56464mRNA_at Hexokinase II -1.3 -1.1 2.0 2.0 metabolism; carbohydrate; glycolytic    
D26393exon_s_at Hexokinase II -1.9 1.2 1.7 2.2 metabolism; carbohydrate; glycolytic    
rc_AI007857_at HGF-regulated tyrosine kinase substrate (Hrs) -1.2 2.0 2.0 1.4 regulatory; growth/proliferation; proliferation; negative intracellular trafficking; zinc ion binding activity; Src; endosome; negative regulation of cell proliferation; differentiation  
rc_AA892014_s_at HLA-B associated transcript 1 (Bat1) 1.4 1.3 1.8 2.2 regulatory; mRNA processing DEAD RNA helicase  
AB007689_at homer, neuronal immediate early gene 2 -1.1 -3.1 -4.8 -5.3 regulatory; signal transduction metabotropic glutamate receptor signaling pathway; GKAP/Homer scaffold activity  
AB007690_s_at homer, neuronal immediate early gene 2 -1.4 -3.2 -8.6 -13.7 regulatory; signaling metabotropic glutamate receptor signaling pathway; GKAP/Homer scaffold activity  
M65251_s_at Human immunodeficiency virus type I enhancer-binding protein 2 1.2 1.6 2.0 2.1 regulatory; transcription metal ion binding activity  
X96437mRNA_g_at immediate early response 3 (IEX-3 or Prg1) 3.4 2.1 2.2 1.1 regulatory; transcription apoptosis inhibitor; cAMP responsive This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis.
rc_AA799566_g_at incisor protein 1.7 6.2 3.7 3.3 regulatory; transcription DNA repair; stress or injury  
L23148_g_at Inhibitor of DNA binding 1, helix-loop-helix protein (splice variation) -1.6 -2.9 -2.1 -2.6 regulatory; transcription SMAD; development; Ebox; myogenesis  
M31837_at insulin-like growth factor binding protein 3 1.5 1.3 2.6 1.2 regulatory; growth/proliferation; growth factor activity; IGF; secreted growth factor activity; myogenesis  
M62781_at Insulin-like growth factor-binding protein 5 3.7 3.0 8.4 4.1 regulatory; growth/proliferation; growth factor activity IGF; secreted growth factor activity; myogenesis  
rc_AI029920_s_at Insulin-like growth factor-binding protein 5 4.7 2.8 6.0 4.3 regulatory; growth/proliferation; growth factor activity; IGF; secreted growth factor activity; myogenesis  
U69272_at Interleukin 15 2.2 2.0 2.1 3.0 regulatory; growth/proliferation; growth factor activity; positive apoptosis; secreted growth factor activity; cytokine signaling; endosome; JAK-STAT This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6.
AF015719_s_at Interleukin 15 3.8 1.9 1.4 1.6 regulatory; growth/proliferation;proliferation; positive apoptosis; secreted growth factor activity; cytokine signaling; endosome; JAK-STAT This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6.
rc_AI176621_at iron-responsive element-binding protein 2.0 2.7 2.5 1.9 regulatory; mRNA processing iron homeostasis; RNA stability  
rc_AA892314_at Isocitrate dehydrogenase 1, soluble 2.0 2.0 2.3 1.4 metabolism; carbohydrate; glycolytic    
U13396_g_at Janus kinase 2 (a protein tyrosine kinase) 2.3 3.1 2.1 1.2 regulatory; signal transduction JAK-STAT; cytokine signaling; negative regulation of cell proliferation; differentiation  
M19647_f_at kallikrein 1 1.3 2.1 2.2 -1.2 protein turnover; proteolysis; protease    
D12769_g_at Kruppel-like factor 9 1.5 1.9 2.2 2.3 regulatory; transcription JNK  
M54926_at Lactate dehydrogenase A 1.0 1.3 1.8 2.7 metabolism; carbohydrate; glycolytic    
rc_AA859581_at Late gestation lung protein -1.1 -2.2 -1.6 -1.2 uknown morphogenesis  
L03294_g_at Lipoprotein lipase -1.1 -2.4 -1.8 -1.7 metabolism; lipid; uptake and transport    
L03294_at Lipoprotein lipase -1.1 -2.3 -1.8 -1.7 metabolism; lipid; uptake and transport    
U97146_at Lysophospholipase 1.3 2.4 1.6 1.3 regulatory; signal transduction phosopholipase Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids.
AF004661_at mannose-binding protein associated serine protease-1 1.3 1.7 2.5 3.4 protein turnover; proteolysis; serine protease    
D50564_at Mercaptopyruvate sulfurtransferase 1.5 2.5 2.3 1.9 stress; oxidative/toxic    
rc_AI169327_at Metalloproteinase-1, tissue inhibitor of- -1.2 -2.2 -1.4 -2.3 protein turnover; proteolysis; protease inhibitor    
rc_AI169327_g_at Metalloproteinase-1, tissue inhibitor of- -1.3 -12.2 -4.2 -12.4 protein turnover; proteolysis; protease inhibitor    
M93401_at methylmalonate semialdehyde dehydrogenase gene 1.5 1.8 2.1 1.7 protein turnover; metabolism; protein; amino acid    
AF095741_g_at Mg87 protein 1.4 2.0 1.6 1.8 unknown    
X14254cds_at MHC class II-associated invariant chain 2.5 2.6 9.3 7.1 stress; immune; antigen    
X14254cds_g_at MHC class II-associated invariant chain 1.1 1.5 5.4 2.6 stress; immune; antigen    
rc_AA957930_s_at Microtubule-associated protein tau -1.0 -1.4 -1.7 -2.1 cytoskeleton/sarcomere; structural    
rc_AI227608_s_at Microtubule-associated protein tau -1.1 -1.8 -2.9 -5.7 cytoskeleton/sarcomere; structural    
X79321_at Microtubule-associated protein tau -1.0 -1.4 -1.7 -2.6 cytoskeleton/sarcomere; structural    
rc_AA799508_at Microtubule-associated proteins 1A/1B light chain 3 1.2 1.6 1.5 2.1 cytoskeleton/sarcomere; structural    
U05784_s_at Microtubule-associated proteins 1A/1B light chain 3 1.1 2.3 3.2 1.5 cytoskeleton/sarcomere; structural    
Y09333_at Mitochondrial acyl-CoA thioesterase 1 1.1 -1.9 -1.5 -2.1 metabolism; lipid; FA oxidation    
rc_AA892400_at mitochondrial CCA-adding tRNA-nucleotidyltransferase, ESTs (human) 1.9 2.2 3.3 2.1 unknown    
U48596_g_at Mitogen activated protein kinase kinase kinase 1; Map3k1 2.3 1.6 1.4 1.5 regulatory; signal transduction MAPK; MEK; JNK; ERK; p38; apoptosis; cytokine signaling  
rc_AI011376_at Mitogen-activated protein kinase kinase 2, EST (mouse) 2.3 2.6 2.8 1.7 regulatory; signal transduction MAPK; MEK; JNK; ERK; p38; apoptosis; cytokine signaling  
rc_AA955477_g_at Mitogen-activated protein kinase kinase 2, EST (mouse) 1.4 2.3 2.3 1.9 regulatory; signal transduction MAPK; MEK; JNK; ERK; p38; apoptosis; cytokine signaling  
rc_AA925300_at Mitogen-activated protein kinase kinase kinase 3 1.2 1.1 2.1 1.1 regulatory; signal transduction MAPK; MEK; JNK; ERK; p38; apoptosis; cytokine signaling  
U87627_at Monocarboxylate transporter 1.4 1.8 1.8 3.4 metabolism; carbohydrate; glycolytic    
X90642mRNA_at Multidrug resistance protein (ID:1) 4.5 5.2 3.7 5.6 unknown    
X81193_at Muscle LIM protein; cysteine-rich protein -2.3 -3.7 -2.1 -1.9 regulatory; cytoskeletal regulator development; differentiation; myogenesis; LIM  
rc_AA851223_at Muscle specific enolase (beta beta enolose) 1.1 1.8 2.0 4.1 metabolism; carbohydrate; glycolytic    
K00512_at Myelin basic protein 1.2 1.2 1.9 2.3 regulatory; PI3k development; Pi3K; neurogenesis  
AB019393_at myocilin 2.4 2.0 1.3 1.7 regulatory; cytoskeletal regulator cytoskeletal organization  
M84176_at Myogenic regulatory factor D 3.4 3.5 5.8 3.0 regulatory; transcription development; differentiation; myogenesis  
S68736_at Myosin heavy chain 2D/2X -1.6 30.0 6.3 59.4 contraction; fast; cytoskeleton/sarcomere    
X04267_at myosin heavy chain 3 -1.5 -3.0 -6.5 -4.5 contraction; embryonic; cytoskeleton/sarcomere    
K03468_s_at myosin heavy chain 3 -1.2 -2.6 -4.9 -3.7 contraction; embryonic; cytoskeleton/sarcomere    
L24897_s_at Myosin heavy chain IIx/d 4.0 25.6 120.7 188.3 contraction; fast; cytoskeleton/sarcomere    
M12098_s_at Myosin heavy chain, embryonic -1.4 -4.5 -21.8 -16.1 contraction; embryonic; cytoskeleton/sarcomere    
K03467_s_at Myosin heavy chain, embryonic -1.5 -3.2 -19.4 -16.2 contraction; embryonic; cytoskeleton/sarcomere    
X00975_at Myosin light chain 2, fast -1.1 1.6 1.4 4.8 contraction; fast; cytoskeleton/sarcomere    
X00975_g_at Myosin light chain 2, fast -1.2 1.6 1.4 5.5 contraction; fast; cytoskeleton/sarcomere    
M11851_at Myosin light chain 2, slow -1.3 -6.2 -23.1 -10.4 contraction; slow; cytoskeleton/sarcomere    
X07314cds_at Myosin light chain 2, slow -1.2 -5.3 -61.3 -12.6 contraction; slow; cytoskeleton/sarcomere    
X07314cds_g_at Myosin light chain 2, slow -1.3 -5.3 -36.1 -7.2 contraction; slow; cytoskeleton/sarcomere    
J03886_at Myosin light chain kinase 2, skeletal muscle 1.4 1.6 2.1 1.9 regulatory; cytoskeletal regulator adhesion; cytoskeletal organization; calcium signaling  
X05566_i_at Myosin light chain RLC -1.4 -4.5 -3.7 -2.8 contraction; slow; cytoskeleton/sarcomere    
X54617mRNA_s_at myosin regulatory light chain, exon 4 -1.4 -3.7 -3.2 -2.2 contraction; slow; cytoskeleton/sarcomere    
U04937_s_at Na-Ca exchanger; sodium-calcium exchanger -1.6 -2.8 -6.0 -2.9 contraction; slow; membrane depolarization    
X87157_at Neurolysin (metallopeptidase M3 family) 1.4 1.6 2.3 2.3 protein turnover; proteolysis; protease;    
S72637_s_at NO3; tumor-suppressive gene 1.2 1.4 1.9 2.1 regulatory; growth/proliferation; proliferation; oncogenesis/tumor supressor tumor supressor; cell cycle arrest  
rc_AA799539_at NS1-binding protein, EST (human) 2.8 2.4 3.1 2.4 protein turnover; translation; mRNA processing    
rc_AA891864_at Nuclear ATP/GTP-binding protein, EST (mouse) 1.4 1.9 3.5 3.4 regulatory; signal transduction differnetiation; Purkinje cell degeneration; carboxypeptidase; regeneration NNA1 is a zinc carboxypeptidase that contains nuclear localization signals and an ATP/GTP-binding motif; Nna1 may contribute to nuclear signaling events in differentiating and regenerating neurons
X13167cds_s_at Nuclear Factor IA (Nfia) 1.6 2.2 1.4 -1.1 regulatory; transcription translation regulator activity; cytokine signaling; Y-box binding protein  
U20796_at nuclear receptor subfamily 1, group D, member 2 1.6 2.1 1.4 1.7 regulatory; transcription ligand-dependent nuclear receptor signaling; Rev-ErbA; differentiation; development In summary, HZF-2 alpha/beta are novel orphan nuclear receptors which may play an important role in hormone-dependent aspects of developmental processes modulating hippocampal and cerebellar plasticity
rc_AI176710_at nuclear receptor subfamily 4, group A, member 3 -1.6 -1.3 -1.4 -3.1 regulatory; transcription ligand-dependent nuclear receptor signaling; steroid hormone receptor activity; NGFI-B A cDNA clone of NOR-1 encodes a 68kDa, 628 amino acid residue-containing protein, with an amino acid sequence highly homologous to the Nur77 family in its DNA-binding domain and moderately so in its putative ligand-binding domain. Using mobility shift ass
AF062594_g_at nucleosome assembly protein 1-like 1 1.2 1.6 2.2 1.1 regulatory; growth/proliferation; proliferation; cell cycle; positive positive regulation of cell proliferation This protein participates in DNA replication and may play a role in modulating chromatin formation and contribute to the regulation of cell proliferation.
U17254_at Nur77; Immediate early gene transcription factor NGFI-B -2.4 -1.4 2.4 1.4 regulatory; transcription ligand-dependent nuclear receptor signaling; NGFI-B  
rc_AA893325_at ornithine aminotransferase 1.0 2.8 1.2 1.0 protein turnover; metabolism; protein; amino acid    
J04791_s_at ornitine decarboxylase -3.9 -1.6 -2.3 -2.0 protein turnover; metabolism; protein; amino acid    
J04792_at ornitine decarboxylase -2.0 -2.0 -2.2 -2.3 protein turnover; metabolism; protein; amino acid    
rc_AI175539_at Parvalbumin 1.3 3.1 5.7 5.6 contraction; membrane depolarization    
X62951mRNA_s_at pBUS19 with repetitive elements 1.6 2.5 1.9 1.8 unknown    
U23769_at PDZ and LIM domain 1 (elfin) -1.9 -3.1 -4.9 -3.0 stress; oxidative/toxic    
E03344cds_s_at Peroxisomal membrane protein 3 2.1 1.8 2.2 1.5 regulatory; signal transduction peroxisome organization and biogenesis  
S56508_s_at Phosphatidylinositol 4-kinase 3.9 4.9 6.2 4.3 metabolism; lipid biosynthesis    
U25651_at Phosphofructokinase, muscle 1.4 1.9 2.0 2.4 metabolism; carbohydrate; glycolytic    
U20195_s_at Phosphoglucomutase 1 1.5 1.7 2.1 2.0 metabolism; carbohydrate; glycogenolysis    
rc_AA894296_at Phosphoglucomutase 1 1.2 1.7 2.2 1.6 metabolism; carbohydrate; glycogenolysis    
L11694_at Phosphoglucomutase 1 1.5 1.7 2.4 2.1 metabolism; carbohydrate; glycogenolysis    
S63233_g_at Phosphoglycerate mutase 1 type B -1.8 -2.1 -2.2 -2.3 metabolism; carbohydrate; glycolytic    
X51529_at Phospholipase A2, group IIA 2.3 1.3 1.3 1.9 regulatory; growth/proliferation; proliferation; oncogenesis/tumor supressor tumor suppressor; oncogenesis; calcium signaling; stress or injury  
M20637_s_at Phospholipase C, delta 1 1.3 2.2 2.3 2.1 regulatory; signal transduction calcium signaling  
U16655_at Phospholipase C, delta 4 2.0 2.8 1.8 1.9 regulatory; signal transduction calcium signaling  
M98826mRNA_g_at Phosphorylase kinase, gamma 1.1 2.5 2.9 3.8 metabolism; carbohydrate; glycogenolysis    
X07320_at Phosphorylase kinase, gamma 1 1.2 2.0 2.5 2.9 metabolism; carbohydrate; glycogenolysis    
rc_AI639151_at pinin, ESTs (mouse) 1.9 1.1 2.2 1.4 cytoskeleton/sarcomere; structural    
rc_AA891842_at Podocalyxin precursor 1.9 1.2 1.1 3.6 unknown    
X62841mRNA_at potassium channel protein (2858 bp) 1.5 2.4 2.0 2.8 contraction; unclassified; membrane depolarization    
X78461_at potassium inwardly-rectifying channel, subfamily J, member 12 -1.3 3.7 2.8 2.2 contraction; unclassified; membrane depolarization    
U61729_at proline rich 2 1.3 1.6 2.4 1.5 protein turnover; proteolysis; ubiquitination    
L17318_at proline-rich proteoglycan 2 1.2 1.5 1.0 2.8 regulatory; growth/proliferation; ECM    
D16443_g_at Prostaglandin E receptor 3 ( subtype EP3) -1.0 1.0 -1.1 2.1 regulatory; growth/proliferation; growth factor activity; cAMP responsive; GTP signaling; thermogenesis  
D50694_at Proteasome (prosome, macropain) 26S subunit, ATPase 1.0 2.1 1.7 1.1 protein turnover; proteolysis; protease; proteasome subunit;    
U77918_at Proteasome 26S subunit, ATPase 3 1.0 2.2 1.8 1.1 protein turnover; proteolysis; protease; proteasome subunit;    
D50695_at Proteasome 26S subunit, ATPase 4 (Tat-binding protein) 1.1 2.5 1.8 1.1 protein turnover; proteolysis; protease; proteasome subunit;    
AB000491_at Proteasome 26S subunit, ATPase 5 (SUG1) 1.1 2.3 2.0 1.7 protein turnover; proteolysis; protease; proteasome subunit;    
AJ006340_s_at Proteasome 26S subunit, p112 1.2 2.7 2.6 1.7 protein turnover; proteolysis; protease; proteasome subunit;    
X55986mRNA_s_at Proteasome subunit, alpha 4 1.1 2.2 1.7 -1.2 protein turnover; proteolysis; protease; proteasome subunit;    
L17127_g_at Proteasome subunit, beta 4 (RN3) 1.4 2.4 1.3 1.3 protein turnover; proteolysis; protease; proteasome subunit;    
rc_AI172162_at Proteasome subunit, beta 4 (RN3) 1.1 2.2 1.5 1.1 protein turnover; proteolysis; protease; proteasome subunit;    
U13895_s_at Proteasome subunit, MSS1 1.2 2.6 2.1 1.1 protein turnover; proteolysis; protease; proteasome subunit;    
D26180_at protein kinase C-like 1 1.0 2.2 2.4 1.7 regulatory; signal transduction activation of JUN kinase  
X89225cds_s_at Protein linked to system L-like neutral amino acid transport activity -1.2 -1.4 -1.3 -2.1 protein turnover; metabolism; protein; amino acid    
rc_AA799980_at Protein phosphatase 1B (2C), magnesium-dependent, beta isoform -1.9 -2.1 -1.2 -1.7 regulatory; growth/proliferation; proliferation; oncogenesis/tumor supressor differentiation The mRNA level of type 2C protein phosphatase was enhanced in accordance with the differentiation of the C3H10T1/2 cells into myoblasts induced by the transfection of MyoD cDNA. These results suggest that type 2C protein phosphatase is related to the mech
rc_AI012595_at Protein phosphatase 2 (2A), catalytic subunit, alpha isoform -2.1 -2.5 -1.9 -1.7 regulatory; signal transduction differentiation; insulin Protein phosphatase 2A (PP2A) acts on a number of enzymes involved in the insulin regulation of glucose uptake and glycogen synthesis
X16043cds_at protein phosphatase 2A catalytic subunit isotype alpha -1.7 -2.0 -1.6 -1.9 regulatory; signal transduction differentiation; insulin Protein phosphatase 2A (PP2A) acts on a number of enzymes involved in the insulin regulation of glucose uptake and glycogen synthesis
S90449_at protein phosphatase 2C -1.5 -1.6 -1.1 -2.1 regulatory; signal transduction    
L19933_s_at Protein tyrosine phosphatase, receptor type, D 1.2 1.5 1.9 2.4 regulatory; proliferation; oncogenesis/tumor supressor; transmembrane receptor; neurogenesis; differentiation; oncogenesis; adhesion  
L19180_g_at Protein tyrosine phosphatase, receptor type, D 1.9 4.5 8.8 4.3 regulatory; growth/proliferation; proliferation; oncogenesis/tumor supressor transmembrane receptor; neurogenesis; differentiation; oncogenesis; adhesion  
rc_AA800844_s_at Protein-lysine 6-oxidase -1.3 -1.7 -2.1 -2.3 ECM structrual/regulator    
rc_AA893235_at Putative lymphocyte G0/G1 switch protein 2, EST (mouse) 5.6 2.2 1.6 2.2 regulatory; growth/proliferation; proliferation; cell cycle cell cycle; G0/G1 switch Genes actively involved in the G0/G1 switch (G0S genes) may be differentially expressed during the lectin-induced switch of lymphocytes from the G0 to the G1 phases of the cell cycle
X59993_at Putative zinc finger protein 2.0 1.4 2.3 2.8 regulatory; transcription factor    
U32314_at Pyruvate carboxylase 1.4 1.4 2.3 1.5 metabolism; carbohydrate; glycolytic    
U10357_at pyruvate dehydrogenase kinase 2 1.4 2.0 2.1 1.5 metabolism; carbohydrate; glycolytic    
AF034577_at Pyruvate dehydrogenase kinase, isoenzyme 4 -2.4 -3.2 -1.1 -1.5 metabolism; carbohydrate; glycolytic    
AF062740_g_at Pyruvate dehydrogenase phosphatase isoenzyme 1 4.3 8.8 3.8 2.7 metabolism; carbohydrate; glycolytic    
AF062740_at Pyruvate dehydrogenase phosphatase isoenzyme 1 2.1 2.2 2.0 1.6 metabolism; carbohydrate; glycolytic    
rc_AA818951_at Pyruvate kinase 3 1.1 1.6 2.3 3.0 metabolism; carbohydrate; glycolytic    
D01046_at Rab11b, member RAS oncogene family 1.4 1.4 2.7 2.0 regulatory; signal transduction intracellular trafficking; GTP signaling; Ras  
U12187_at Ras-related associated with diabetes -5.0 -2.0 -2.6 -2.1 regulatory; signal transduction GTP signaling  
M10934_s_at Retinol-binding protein (RBP) 1.7 1.8 1.1 2.2 unknown   carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision
rc_AI175486_at Ribosomal protein S7 -1.1 1.7 1.7 2.2 protein turnover; translation; ribosomal protein    
U25746_at RNA helicase with arginine-serine-rich domain 1.5 2.1 1.1 1.4 protein turnover; translation; mRNA processing    
U25746_g_at RNA helicase with arginine-serine-rich domain 1.3 2.1 1.8 1.4 protein turnover; translation; mRNA processing    
rc_AI228548_at S-100 protein, alpha chain 1.6 1.3 1.3 2.0 regulatory;adhesion calcium signaling; cel cycle; differnetiation; PKC; cytoskeleton This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
M14656_at Secreted phosphoprotein 1 -1.6 -2.5 -1.2 -2.2 regulatory; growth/proliferation; ECM    
rc_AI230247_s_at Selenoprotein P, plasma, 1 1.4 2.2 1.5 1.4 stress; oxidative/toxic    
M69246_at Serine (or cysteine) proteinase inhibitor, clade H, member 1; Collagen binding protein -1.9 -2.0 -2.0 -1.5 protein turnover; proteolysis; protease inhibitor    
rc_AA799791_at serine/threonine kinase 25, ESTs (yeast) 1.4 1.4 2.6 -1.4 regulatory; signal transduction cAMP responsive; PKC; oxidative stress  
Y07534cds_s_at Serpin; Serine protease inhibitor; mitochondrial cytochrome P450 3.8 14.4 15.5 6.6 protein turnover; proteolysis; protease inhibitor    
M38566mRNA_s_at Serpin; Serine protease inhibitor; mitochondrial cytochrome P450 2.4 7.3 8.1 3.4 protein turnover; proteolysis; protease inhibitor    
U25281_at SH3 domain binding protein CR16 2.0 1.7 2.3 5.5 regulatory; signal transduction SH3; cytoskeletal organization  
X91988_at Signal transducer and activator of transcription 5b 1.6 1.6 2.6 1.5 regulatory; transcription cytokine signaling; JAK-STAT  
X62950mRNA_f_at similar to protease [Sus scrofa] 2.5 2.1 1.3 1.4 protein turnover; proteolysis    
D37934_g_at Sirtuin 2 (silent mating type information regulation 2, homolog) 2 1.1 2.8 1.5 1.3 regulatory; transcription chromatin silencing yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
S82383_s_at slow-twitch alpha TM/hTMnm homolog -1.9 -1.5 -1.8 -2.1 contraction; slow; cytoskeleton/sarcomere    
rc_AA891969_at Small Unique Nuclear hormone receptor CoRepressor (C1D) 1.4 2.0 1.7 1.6 regulatory; transcription myogenesis; differentiation; ligand-dependent nuclear receptor signaling We conclude that SUN-CoR is a corepressor and may function as an additional component of the complex involved in transcriptional repression by unliganded and orphan nuclear hormone receptors.
M22253_at Sodium channel, voltage-gated, type 1, alpha polypeptide -4.8 -1.2 -9.3 -1.0 ion transport; sodium/potassium    
AF051561_s_at Solute carrier family 12, member 2 2.3 2.3 1.2 1.4 ion transport; sodium/chloride-potassium/chloride    
L19931_at Solute carrier family 20, member 2 1.5 1.6 2.5 1.6 ion transport; sodium/phosphate symporter    
AB015433_s_at solute carrier family 3, member 2 -1.4 -2.0 -1.9 -3.4 protein turnover; metabolism; protein; amino acid    
U50927_at Solute carrier family 30 (zinc transporter), member 2 1.1 2.0 2.7 1.1 regulatory; vesicle transport endosome; synaptic; zinc binding activity  
J05167_at Solute carrier family 4 member 3 anion exchange protein 3; Cl-/HCO3- exchanger (B3RP3) 1.0 -2.7 -3.1 -2.7 ion transport; sodium/phosphate symporter    
J05166_g_at Solute carrier family 4, member 2 1.9 1.5 2.6 1.4 ion transport inorganic anion exchanger activity; pH regulation; oxidative stress  
rc_AI237576_s_at SPA-1 like protein p1294 1.1 1.6 -2.6 -1.3 regulatory; signal transduction cytoskeletal organization; NMDA; GTPase activating  
L13635_s_at Splicing factor, arginine/serine-rich 5 1.8 1.6 2.2 1.9 protein turnover; translation; mRNA processing    
AB014722_at squamous cell carcinoma antigen recognized by T-cells 1 2.0 1.3 1.4 1.8 regulatory; growth/proliferation; proliferation; oncogenesis/tumor supressor oncogenesis; tumor supressor  
J02585_at Stearoyl-Coenzyme A desaturase 1 3.3 5.8 2.0 6.9 metabolism; lipid; FA oxidation    
rc_AI230712_at Subtilisin - like endoprotease 1.3 1.2 1.3 2.1 protein turnover; proteolysis; protease    
AF065161_at Suppressor of cytokine signaling (SOCS-1) (Cish1) 3.0 1.3 1.9 1.6 regulatory; signal transduction cytokine signaling; JAK-STAT; MAPK; IGF; apoptosis The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling
AF075382_at Suppressor of cytokine signaling-2 (SOCS-2) (Cish2) 2.3 7.5 1.6 1.7 regulatory; signal transduction cytokine signaling; JAK-STAT; MAPK; IGF; apoptosis The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling
rc_AI639484_at Synaptic vesicle glycoprotein 2b 10.8 3.2 1.2 2.6 regulatory; vesicle transport development  
S45663_at Synaptic vesicle glycoprotein Sc2 1.2 -1.5 -2.1 -1.8 regulatory; growth/proliferation; growth factor development; synaptic  
S61868_g_at Syndecan-4 -2.2 -1.6 -1.2 -1.3 regulatory; adhesion adhesion  
X86789_at synuclein, gamma 1.3 1.8 2.8 5.5 regulatory; growth/proliferation; proliferation; oncogenesis/tumor supressor oncogenesis  
D89730_at T16 1.7 2.2 1.8 1.9 unknown    
rc_AA800962_at Talin; ESTs (mouse) -1.2 -3.9 -1.3 -1.3 regulatory; adhesion adhesion  
U89282_at Telomerase protein component 1 1.4 1.8 2.1 1.6 regulatory; transcription chromatin  
X15705cds_at Testis-specific heat shock protein-related gene hst70 -2.1 -2.3 -2.5 -1.7 protein turnover; protein folding    
rc_AI172476_at TGF-B inducible early growth response 1.8 2.5 2.8 1.9 regulatory; transcription SMAD; TGFbeta receptor signaling pathway TIEG amplies Smad signaling.
rc_AI014169_at Thioredoxin interacting factor; Vdup1 upregulated by 1,25-dihydroxyvitamin D-3 1.6 2.4 1.7 1.5 stress; oxidative/toxic    
rc_AI237654_at Thioredoxin interacting factor; Vdup1 upregulated by 1,25-dihydroxyvitamin D-3 1.6 2.1 2.2 1.8 stress; oxidative/toxic    
X56228_at Thiosulfate sulphurtransferase (rhodanese) 1.5 2.0 3.2 2.0 stress; oxidative/toxic    
X56228_g_at Thiosulfate sulphurtransferase (rhodanese) 4.3 6.9 7.4 3.4 stress; oxidative/toxic    
K01934mRNA#2_at Thrsp, thyroid hormone responsive SPOT14 homolog (Rattus) 2.1 4.3 1.1 8.2 regulatory; signal transduction   possible involvement in human lipid disorders; Identification of genes enhanced by protein-calorie malnutrition
L14463_at Transducin-like enhancer of split 4 (E(sp1) homolog; EST (rat) 1.4 1.3 2.4 1.3 regulatory; transcription development; differentiation; Notch signaling; myogenesis  
rc_AA875084_at Transducin-like enhancer of split 4 (E(sp1) homolog; EST (rat) 2.4 3.0 3.6 3.2 regulatory; transcription development; differentiation; Notch signaling; myogenesis  
M58040_at Transferrin receptor 3.0 -1.7 -1.8 -1.7 stress; oxidative/toxic    
M83107_at Transgelin, SM22 alpha -3.7 -4.3 -2.5 -1.7 regulatory; cytoskeletal regulator cytoskeletal organization  
M83107_g_at Transgelin, SM22 alpha -2.2 -2.8 -1.6 -1.7 regulatory; cytoskeletal regulator cytoskeletal organization  
Y13275_at Transmembrane 4 superfamily member; tetraspanin 1.1 1.2 4.5 5.1 regulatory; signal transduction adhesion  
AB006914_at Trip 10, thyroid hormone receptor interactor 10 1.3 1.5 2.1 1.7 regulatory; cytoskeletal regulator cytoskeletal organization; SH3  
M15474cds_s_at Tropomyosin 1 (alpha) 1.2 2.4 1.8 9.7 contraction; fast; cytoskeleton/sarcomere    
M34134_s_at Tropomyosin 1 (alpha) 1.1 2.2 1.8 6.4 contraction; fast; cytoskeleton/sarcomere    
X02412_at Tropomyosin 3 alpha -1.1 1.1 1.5 5.3 contraction; unclassified; cytoskeleton/sarcomere    
rc_AA799680_at tropomyosin, alpha-; EST (rat) 1.7 1.9 1.9 2.3 contraction; fast; cytoskeleton/sarcomere    
rc_AI639532_at Troponin C, fast skeletal EST (mouse) 1.0 2.1 2.4 9.5 contraction; fast; cytoskeleton/sarcomere    
M73701_at Troponin I, skeletal, fast 2 1.0 2.7 1.8 12.9 contraction; fast; cytoskeleton/sarcomere    
J04993_at Troponin I, skeletal, slow 1 -1.2 -2.4 -2.4 -2.2 contraction; slow; cytoskeleton/sarcomere    
rc_AI136540_at Troponin T, fast skeletal -1.0 2.5 1.7 8.6 contraction; fast; cytoskeleton/sarcomere    
rc_AA800948_at Tubulin alpha-1 chain; EST (rat) -3.1 -4.3 -4.9 -1.0 cytoskeleton/sarcomere; structural    
rc_AA799591_at Tubulin, beta-, EST (rat) -2.0 -2.3 -1.6 -1.2 cytoskeleton/sarcomere; structural    
rc_AA799641_g_at tumor differentially expressed 1, ESTs (mouse) 1.4 1.7 1.1 2.5 unknown    
D17296_at Ubiquitin C 2.0 2.1 2.4 1.5 protein turnover; proteolysis; ubiquitination    
rc_AI639312_at Ubiquitin-protein ligase E3 (Atrogin1) 1.9 2.0 3.0 1.8 protein turnover; proteolysis; ubiquitination    
U50842_at Ubiquitin-protein ligase E3 (Nedd4) 2.2 2.5 2.9 1.7 protein turnover; proteolysis; ubiquitination    
AF035943_at Uncoupling protein 3, mitochondrial 1.4 -1.1 2.6 1.2 ion transport; hydrogen    
U58858_at unction plakoglobin 1.7 1.6 1.9 2.1 regulatory; cytoskeletal regulator cytoskeletal organization  
X84997mRNA#5_at Variable coding sequence A1 -2.0 -5.9 -1.5 -2.5 unknown    
M32167_g_at Vascular endothelial growth factor-A188 -1.4 -2.3 -1.6 -1.7 regulatory; growth/proliferation; growth factor activity; positive positive regulation of cell proliferation  
U96490_at Yip1p-interacting factor -1.1 -2.7 -1.5 -1.3 regulatory; signal transduction GTP signaling; intracellular trafficking