Recent Publications


1. Pro-IL-16 recruits histone deacetylase 3 to the Skp2 core promoter through interaction with transcription factor GABP.

Zhang Y, Tuzova M, Xiao ZX, Cruikshank WW, Center DM.

J Immunol. 2008 Jan 1;180(1):402-408;

2. A homologous form of human interleukin 16 is implicated in microglia recruitment following nervous system injury in leech Hirudo medicinalis.

Croq F, Vizioli J, Tuzova M, Tahtouh M, Sautiere PE, Van Camp C, Salzet M, Cruikshank WW, Pestel J, Lefebvre C.

Glia. 2010 Nov 1;58(14):1649-1662;

3. Interleukin-16 as a marker of Sézary syndrome onset and stage.

Richmond J, Tuzova M, Parks A, Adams N, Martin E, Tawa M, Morrison L, Chaney K, Kupper TS, Curiel-Lewandrowski C, Cruikshank W.

J Clin Immunol. 2011 Feb;31(1):39-50;

4. Loss of nuclear pro-IL-16 facilitates cell cycle progression in human cutaneous T cell lymphoma.

Curiel-Lewandrowski C, Yamasaki H, Si CP, Jin X, Zhang Y, Richmond J, Tuzova M, Wilson K, Sullivan B, Jones D, Ryzhenko N, Little F, Kupper TS, Center DM, Cruikshank WW.

J Clin Invest. 2011 Dec;121(12):4838-4849;

5. Introduction of pro-interleukin-16 inhibits T-lymphoblastic leukemia growth in mice.

Richmond J, Finkel M, Studwell A, Little F, Cruikshank W.

J Cancer Res Clin Oncol. 2011 Oct;137(10):1581-1585;

6. Preferential migration of T regulatory cells induced by IL-16.

McFadden C, Morgan R, Rahangdale S, Green D, Yamasaki H, Center D, Cruikshank W.

J Immunol. 2007 Nov 15;179(10):6439-6445;

7. Histamine 4 receptor activation induces recruitment of FoxP3+ T cells and inhibits allergic asthma in a murine model.

Morgan RK, McAllister B, Cross L, Green DS, Kornfeld H, Center DM, Cruikshank WW.

J Immunol. 2007 Jun 15;178(12):8081-8089;

8. Neutralization of interleukin-16 protects nonobese diabetic mice from autoimmune type 1 diabetes by a CCL4-dependent mechanism.

Meagher C, Beilke J, Arreaza G, Mi QS, Chen W, Salojin K, Horst N, Cruikshank WW, Delovitch TL.

Diabetes. 2010 Nov;59(11):2862-1271;

9. Immunosuppressive effect on T cell activation by interleukin-16- and interleukin-10-cDNA-double-transfected human squamous cell line.

Matsumoto Y, Fujita T, Hirai I, Sahara H, Torigoe T, Ezoe K, Saito T, Cruikshank WW, Yotsuyanagi T, Sato N.

Burns. 2009 May;35(3):383-389;

10. Regulation of cellular processes by interleukin-16 in homeostasis and cancer.

Richmond J, Tuzova M, Cruikshank W, Center D. J Cell Physiol. 2014 Feb;229(2):139-47. doi: 10.1002/jcp.24441. Review.

11. Marina TuzovaJillian RichmondDeon WolpowitzClara Curiel-LewandrowskiKeri ChaneyThomas KupperWilliam Cruikshank


Leukemia & Lymphoma Accepted for publication: 1–28.

Posted online on 2 May 2014.

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By Marina Tuzova
August 15th, 2012 in What's new?.

Albert Ge and Marina Tuzova during poster session

Albert Ge and Marina Tuzova during poster session



1. We  submitted a paper to the Leukemia & Lymphoma Journal, which clarifies the additive effects of IL-16 and TSLP in early stages of Mycosis Fungoides, cannot wait for the review! ACCEPTED!!! AVAILABLE online!!!!
2. Another paper was submitted to Exp. Dermatology – the causes of pruritus in CTCL. Expecting the review as well.
3. we have two papers under review right now – 

-GGsTop, a Specific γ-Glutamyl Transferase Inhibitor, as a Novel Treatment for Asthma 

– Selective S1P1 desensitization of CD4+ T Lymphocytes by IL-16 Results in Th2 Accumulation in the Lymph Nodes