Summary list of publications:
Hasselmo home page

Summary list of publications:


Papers: (Click on "PDF" at end of citation to download PDF files)

PEER REVIEWED JOURNAL ARTICLES:

2011

Brandon, M.P., Bogaard, A.R., Libby, C.P., Connerney, M.A., Gupta, K., Hasselmo, M.E. (2011) Reduction of theta rhythm dissociates grid cell spatial periodicity from directional tuning. Science, 332: 595-599. Abstract Full text PDF

Yoshida, M., Giocomo, L.M., Boardman, I., Hasselmo, M.E. (2011) Frequency of subthreshold oscillations at different membrane potential voltages in neurons at different anatomical positions on the dorsoventral axis in the rat medial entorhinal cortex. J Neurosci. 31(35):12683-94. PMCID: PMC3177240. PDF

Brandon, M.P., Bogaard, A.R., Andrews, C., Hasselmo, M.E. (2011) Head direction cells in the postsubiculum do not show replay of prior waking sequences during sleep. Hippocampus, in press. PDF

Hasselmo, M.E., Sarter, M. (2011) Modes and models of forebrain cholinergic neuromodulation of cognition. Neuropsychopharmacology, 36: 52-73. PMCID: PMC2992803. PDF

Hyman, J.M., Hasselmo, M.E., Seamans, J.K. (2011) What is the functional relevance of prefrontal cortex entrainment to hippocampal theta rhythms? Front. Neurosci. 5: 24. PMCID: PMC3052540. PDF

Navratilova, Z., Giocomo, L.M., Fellous, J.M., Hasselmo, M.E., McNaughton, B.L. (2011) Phase precession and variable spatial scaling in a periodic attractor map model of medial entorhinal grid cells with realistic after-spike dynamics. Hippocampus, In press. PDF

2010

Hasselmo, M.E., Giocomo. L.M., Brandon, M.P., Yoshida, M. (2010) Cellular dynamical mechanisms for encoding the time and place of events along spatiotemporal trajectories in episodic memory. Behav. Brain Res. 215: 261-274. PMCID: PMC2891577. PDF

Heys, J.G., Giocomo, L.M., Hasselmo, M.E. (2010) Cholinergic modulation of the resonance properties of stellate cells in layer II of medial entorhinal cortex. J. Neurophysiol. 104(1): 258-70. PMCID: PMC2904208. PDF

Zilli, E.A., Hasselmo, M.E. (2010) Coupled noisy spiking neurons as velocity-controlled oscillators in a model of grid cell spatial firing. J. Neurosci. 30: 13850-13860. PMCID: PMC2978507 PDF

Brown, T.H., Ross, B., Keller, J., Hasselmo, M.E., Stern, C.E. (2010) Which way was I going? Contextual retrieval supports the disambiguation of well-learned overlapping navigational routes. J. Neurosci. 30(21): 7414-22. PMCID: PMC2905880. PDF

Hyman, J.M., Zilli, E.A., Paley, A.M., Hasselmo, M.E. (2010) Working memory performance correlates with prefrontal-hippocampal theta interactions but not with prefrontal neuron firing rates. Front. Integr. Neurosci. 4:2. PMCID: PMC2861479 PDF

2009

Giocomo, L.M., Hasselmo, M.E. (2009) Knock-out of HCN1 subunit flattens dorsal-ventral frequency gradient of medial entorhinal neurons in adult mice. Journal of Neuroscience 29(23): 7625-30. PMCID 2729850. PDF

Yoshida, M., Hasselmo, M.E. (2009) Persistent firing supported by an intrinsic cellular mechanism in a component of the head direction system. Journal of Neuroscience 29(15): 4945-52. PMCID2704018. PDF

Hasselmo, M.E. (2009) A model of episodic memory: Mental time travel along encoded trajectories using grid cells. Neurobiology of Learning and Memory 92(4): 559-73. PDF

Hasselmo, M.E., Brandon, M.P., Yoshida, M., Giocomo, L.M., Heys, J.G., Fransen, E., Newman, E.L., Zilli, E.A. (2009) A phase code for memory could arise from circuit mechanisms in entorhinal cortex. Neural Networks 22(8):1129-38. PDF

Schon, K., Quiroz, Y.T., Hasselmo, M.E., Stern, C.E. (2009) Greater working memory load results in greater medial temporal activity at retrieval. Cereb. Cortex 19(11): 2561-71. PMCID: 2758675. PDF

Zilli, E.A., Yoshida, M., Tahvildari, B., Giocomo, L.M., Hasselmo, M.E. (2009) Evaluation of the oscillatory interference model of grid cell firing through analysis of measured period variance of some biological oscillators. PLoS Comput Biol. 5(11): e1000573. PDF

Brandon, M.P., Hasselmo, M.E. (2009) Sources of the spatial code within the hippocampus. F1000 Biol. Rep. 1.pii: 3. PMCID: PMC2920688. PDF

2008


Giocomo, L.M., Hasselmo, M.E. (2008) Time constant of I(h) differs along dorsal to ventral axis of medial entorhinal cortex. Journal of Neuroscience, 28:9414-25. PDF

Hasselmo, M.E. (2008) Temporally structured replay of neural activity in a model of entorhinal cortex, hippocampus and postsubiculum. Eur. J. Neurosci. 28:1301-1315. PDF

Hasselmo, M.E. (2008) Grid cell mechanisms and function: Contributions of entorhinal persistent spiking and phase resetting. Hippocampus 18(12): 1116-26. PDF

Yoshida, M., Fransen, E., Hasselmo, M.E. (2008) mGluR-dependent persistent firing in entorhinal cortex layer III neurons. Eur. J. Neurosci. 28:1116-26. PDF

Zilli, E.A., Hasselmo, M.E. (2008) Analyses of Markov decision process structure regarding the possible strategic use of interacting memory systems. Frontiers Comput. Neurosci. 2:6. PDF

Giocomo, L.M., Hasselmo, M.E. (2008) Computation by oscillations: Implications of experimental data for theoretical models of grid cells. Hippocampus 18(12): 1186-1199. PDF

Hasselmo, M.E., Brandon, M.P. (2008) Linking cellular mechanisms to behaviour: Entorhinal persistent spiking and membrane potential oscillations may underlie path integration, grid cell firing and episodic memory. Neural Plasticity, 2008: 658323. PDF

Hasselmo, M.E. (2008) Neuroscience. The scale of experience. Science. 321(5885):46-7. Full text

Zilli, E.A., Hasselmo, M.E. (2008) Modeling the role of working memory and episodic memory in behavioral tasks. Hippocampus, 18(2):193-209. PDF

Koene RA, Hasselmo ME. (2008) Reversed and forward buffering of behavioral spike sequences enables retrospective and prospective retrieval in hippocampal regions CA3 and CA1. Neural Networks 21:276-88.

Zilli, E.A., Hasselmo, M.E. (2008) The influence of Markov decision process structure on the possible strategic use of working memory and episodic memory. PloS ONE 3(7): e2756. PDF


2007

Giocomo LM, Zilli EA, Fransen E, Hasselmo ME. (2007) Temporal frequency of subthreshold oscillations scales with entorhinal grid cell field spacing. Science, 315(5819):1719-22. Abstract Full text

Hasselmo ME, Giocomo LM, Zilli EA (2007) Grid cell firing may arise from interference of theta frequency membrane potential oscillations in single neurons. Hippocampus, 17(12): 1252-1271. PDF

Hasselmo ME (2007) Arc length coding by interference of theta frequency oscillations may underlie context-dependent hippocampal unit data and episodic memory function. Learn. Mem. 14: 782-794. PDF

Griffin AL, Eichenbaum H, Hasselmo ME. (2007) Spatial representations of hippocampal CA1 neurons are modulated by behavioral context in a hippocampus-dependent memory task. J Neurosci. 27(9):2416-23 PDF

Tahvildari B, Fransen E, Alonso AA, Hasselmo ME. (2007) Switching between "On" and "Off" states of persistent activity in lateral entorhinal layer III neurons. Hippocampus. 17(4):257-63. PDF

Manns, J.R., Zilli, E.A., Ong, K.C., Hasselmo, M.E., Eichenbaum, H. (2007) Hippocampal CA1 spiking during encoding and retrieval: Relation to theta phase. Neurobiol. Learn. Mem., 87(1):9-20. PDF

Katz Y, Kath WL, Spruston N, Hasselmo ME. (2007) Coincidence detection of place and temporal context in a network model of spiking hippocampal neurons. PLoS Comput Biol. 3(12):e234. PMCID: PMC2134961

Giocomo LM, Hasselmo ME (2007) Neuromodulation by glutamate and acetylcholine can change circuit dynamics by regulating the relative influence of afferent input and excitatory feedback. Mol. Neurobiol. 36(2): 184-200.

2006


Hasselmo, M.E., Stern, C.E. (2006) Mechanisms underlying working memory for novel information. Trends in Cognitive Sciences, 10(11):487-93. PDF

Lee, I., Griffin, A.L., Zilli, E.A., Eichenbaum, H., Hasselmo, M.E. (2006) Gradual translocation of spatial correlates of neuronal firing in the hippocampus toward prospective reward locations. Neuron, 51(5):639-50. PDF

Hasselmo, M.E. (2006) The role of acetylcholine in learning and memory. Curr. Opinion Neurobiol. 16(6): 710-715. PDF

Fransen, E., Tahvildari, B., Egorov, A.V., Hasselmo, M.E. and Alonso, A.A. (2006) Mechanism of graded persistent cellular activity of entorhinal cortex layer V pyramidal neurons. Neuron, 49(5): 735-746. PDF

Zilli, E.A., Hasselmo, M.E. (2006) An analysis of the mean theta phase of population activity in a model of hippocampal region CA1. Network: Computation in Neural Systems, 17(3):277-97. PDF

Giocomo, L.M., Hasselmo, M.E. (2006) Difference in time course of modulation of synaptic transmission by group II versus group III metabotropic glutamate receptors in region CA1 of the hippocampus. Hippocampus. 16(11):1004-16. PDF

Koene, R.A., Hasselmo, M.E. (2006) First-in-first-out item replacement in a model of short-term memory based on persistent spiking. Cereb. Cortex. Epub ahead of print. PDF

Siekmeier, P.J., Hasselmo, M.E., Howard, M.W., Coyle, J. (2006) Modeling of context-dependent retrieval in hippocampal region CA1: Implications for cognitive function in schizophrenia. Schizophr. Res. 89(1-3):177-90. PDF

Kremin, T., Gerber, D., Giocomo, L.M., Huang, S.Y., Tonegawa, S., Hasselmo, M.E. (2006) Muscarinic suppression in stratum radiatum of CA1 shows dependence on presynaptic M1 receptors and is not dependent on effects at GABAB receptors. Neurobiol. Learning and Mem., 85(2):153-163. PDF

2005


Hasselmo, M.E. (2005) A model of prefrontal cortical mechanisms for goal directed behavior. Journal of Cognitive Neuroscience, 17(7):1115-29. PDF MATLAB script demonstrating models
Hasselmo M.E. (2005) What is the function of hippocampal theta rhythm?--Linking behavioral data to phasic properties of field potential and unit recording data. Hippocampus. 15(7):936-49. PDF

Hasselmo, M.E. and Eichenbaum, H. (2005) Hippocampal mechanisms for the context-dependent retrieval of episodes. Neural Networks, 18(9):1172-1190. PDF MATLAB script demonstrating models

Koene, R.A. and Hasselmo, M.E. (2005) An integrate and fire model of prefrontal cortex neuronal activity during performance of goal-directed decision making. Cerebral Cortex, 15(12):1964-81. PDF

Hasselmo, M. (2005) Expecting the unexpected: Modeling of neuromodulation. Neuron 46(4):526-528. PDF

McGaughy J, Koene RA, Eichenbaum H, Hasselmo ME. (2005) Cholinergic deafferentation of the entorhinal cortex in rats impairs encoding of novel but not familiar stimuli in a delayed nonmatch-to-sample task. J Neurosci. 25(44):10273-81. PDF

Hyman JM, Zilli EA, Paley AM, Hasselmo ME (2005) Medial prefrontal cortex cells show dynamic modulation with the hippocampal theta rhythm dependent on behavior. Hippocampus. 15(6):739-49. PDF

Kunec, S., Hasselmo, M., Kopell N. (2005) Encoding and retrieval in the CA3 region of the hippocampus: a model of theta phase separation. J. Neurophysiol. 94(1):70-82. PDF

Schon K, Atri A, Hasselmo ME, Tricarico MD, LoPresti ML, Stern CE (2005) Scopolamine reduces persistent activity related to long-term encoding in the parahippocampal gyrus during delayed matching in humans. J Neurosci. 25(40):9112-23 PDF

Howard MW, Fotedar MS, Datey AV, Hasselmo ME. (2005) The temporal context model in spatial navigation and relational learning: toward a common explanation of medial temporal lobe function across domains. Psychol Rev. 112(1):75-116.

Gorchetchnikov, A. and Hasselmo, M.E. (2005) A biophysical implementation of a bidirectional graph search algorithm to solve multiple goal navigation tasks. Connection Science, 17: 145-164. PDF

Hasselmo, M.E. (2005) The role of hippocampal regions CA3 and CA1 in matching entorhinal input with retrieval of associations between objects and context: theoretical comment on Lee et al. (2005). Behav. Neurosci. 119: 342-345.

Giocomo LM, Hasselmo ME (2005) Nicotinic modulation of glutamatergic synaptic transmission in region CA3 of the hippocampus. Eur J Neurosci. 22(6):1349-56 PDF

Gorchetchnikov A, Versace M, Hasselmo ME (2005) A model of STDP based on spatially and temporally local information: derivation and combination with gated decay. Neural Netw. 18(5-6):458-66. PDF

2004


Hasselmo, M.E. and McGaughy, J. (2004) High acetylcholine levels set circuit dynamics for attention and encoding and low acetylcholine levels set dynamics for consolidation. Progress in Brain Research 145: 207-231. PDF

Judge, S.J. and Hasselmo, M.E. (2004) Theta rhythmic stimulation of stratum lacunosum-moleculare in rat hippocampus contributes to associative LTP at a phase offset in stratum radiatum. J Neurophysiol. 92(3):1615-24. PDF

Wyble, B.P., Hyman, J.M., Rossi, C.A., Hasselmo, M.E. (2004) Analysis of theta power in hippocampal EEG during bar pressing and running behavior in rats during distinct behavioral contexts. Hippocampus, 14(5):662-74. PDF

Schon, K., Hasselmo, M.E., Lopresti, M.L., Tricarico, M.D., and Stern, C.E. (2004) Persistence of parahippocampal representation in the absence of stimulus input enhances long-term encoding: A functional magnetic resonance imaging study of subsequent memory after a delayed match-to-sample task. J. Neurosci. 24: 11088-97. PDF

Fransen, E., Alonso AA, Dickson CT, Magistretti J, Hasselmo, M.E. (2004) Ionic mechanisms in the generation of subthreshold oscillations and action potential clustering in entorhinal layer II stellate neurons. Hippocampus, 14(3):368-84. PDF

Atri, A., Sherman, S.J., Norman, K.A., Kirchhoff, B.A., Nicolas, M.M., Greicius, M.D., Cramer, S.C., Breiter, H.C., Hasselmo, M.E., Stern, C.E. (2004) Blockade of central cholinergic receptors impairs new learning and increases proactive interference in a word paired-associate memory task. Behavioral Neurosci. 118(1):223-236. PDF

2003



Hyman, J.M., Wyble, B.P., Goyal, V., Rossi, C.A., Hasselmo, M.E. (2003) Stimulation in hippocampal region CA1 in behaving rats yields LTP when delivered to the peak of theta and LTD when delivered to the trough. J. Neurosci. 23(37):11725-31. PDF

Linster, C., Maloney, M., Patil, M. and Hasselmo, M.E. (2003) Enhanced cholinergic suppression of previously strengthened synapses enables the formation of self-organized representations in olfactory cortex. Neurobiol. Learn. Mem. 80(3): 302-314. PDF

Koene, R.A., Gorchetchnikov, A., Cannon, R.C. and Hasselmo M.E. (2003) Modeling goal-directed spatial navigation in the rat based on physiological data from the hippocampal formation. Neural Networks 16(5-6):577-84. PDF

Sherman, S.J., Atri, A., Hasselmo, M.E., Stern, C.E., Howard, M.W. (2003) Scopolamine impairs human recognition memory: Data and modeling. Behavioral Neuroscience, 117(3): 526-539.

2002



Hasselmo, M.E., Bodelon, C. and Wyble, B.P. (2002) A proposed function for hippocampal theta rhythm: Separate phases of encoding and retrieval enhance reversal of prior learning. Neural Computation, 14(4): 793-817. PDF
Appendix showing transition from equation 12 to equation 13. PDF
Molyneaux, B.J., Hasselmo, M.E. (2002) GABA(B) Presynaptic Inhibition Has an In Vivo Time Constant Sufficiently Rapid to Allow Modulation at Theta Frequency. J Neurophysiol. 87(3):1196-205. PDF
Fransen, E., Alonso, A.A. and Hasselmo, M.E. (2002) Simulations of the role of the muscarinic-activated calcium-sensitive non-specific cation current I(NCM) in entorhinal neuronal activity during delayed matching tasks. J. Neurosci. 22(3):1081-1097. PDF
Hasselmo, M.E., Hay, J., Ilyn, M. and Gorchetchnikov, A. (2002) Neuromodulation, theta rhythm and rat spatial navigation. Neural Networks, 15: 689-707. PDF
Egorov, A.V., Hamam, B.N., Fransen, E., Hasselmo, M.E., Alonso, A.A. (2002) Graded persistent activity in entorhinal cortex neurons. Nature 420(6912):173-8. PDF
Cannon, RC, Hasselmo, ME and Koene, RA (2002) From biophysics to behavior: Catacomb2 and the design of biologically plausible models for spatial navigation. Neuroinformatics, 1(1): 3-42. PDF

2001


Hasselmo, M.E. and Fehlau, B.P. (2001) Differences in time course of cholinergic and GABAergic modulation of excitatory synaptic potentials in rat hippocampal slice preparations. J. Neurophysiol., 86: 1792-1802. PDF
Stern, C.E., Sherman, S.J., Kirchhoff, B.A. and Hasselmo, M.E. (2001) Medial temporal and prefrontal contributions to working memory tasks with novel and familiar stimuli. Hippocampus, 11: 337-346. PDF
Linster C, Hasselmo ME. (2001) Neuromodulation and the Functional Dynamics of Piriform Cortex. Chem Senses, 26(5):585-594. PDF
De Rosa E, Hasselmo ME, Baxter MG (2001) Contribution of the cholinergic basal forebrain to proactive interference from stored odor memories during associative learning in rats. Behav Neurosci. 115(2):314-27.

2000


Wyble, B.P., Linster, C. and Hasselmo, M.E. (2000) Size of CA1-evoked synaptic potentials is related to theta rhythm phase in rat hippocampus. J. Neurophysiol. 83: 2138-2144. PDF
DeRosa, E. and Hasselmo, M.E. (2000) Muscarinic cholinergic neuromodulation reduces proactive interference between stored odor memories during associative learning in rats. Behav. Neurosci. 114: 32-41.
Linster, C. and Hasselmo, M.E. (2000) Neural activity in the horizontal limb of the diagonal band of Broca can be modulated by electrical stimulation of the olfactory bulb and cortex in rats. Neurosci. Lett. 282: 157-160. PDF
Dickson, C.T., Magistretti, J., Shalinsky, M.H., Fransen, E., Hasselmo, M.E., Alonso, A. (2000) Properties and role of I(h) in the pacing of subthreshold oscillations in entorhinal cortex layer II neurons. J Neurophysiol. 83(5):2562-79. PDF
Sohal, V. and Hasselmo, M.E. (2000) A model for experience-dependent changes in the responses of inferotemporal neurons. Network: Comp. Neural Syst. 11: 169-190. PDF

1999


Stern, C.E. and Hasselmo, M.E. (1999) Bridging the gap: Integrating cellular and functional magnetic resonance imaging studies of the hippocampus. Hippocampus 9: 45-53.
Hasselmo, M.E. and McClelland, J.L. (1999) Neural models of memory. Curr. Opinion Neurobiol. 9: 184-188. PDF
Hasselmo, M.E. (1999) Neuromodulation: Acetylcholine and memory consolidation. Trends in Cognitive Sciences 3: 351-359. PDF
Linster, C., Wyble, B. and Hasselmo, M.E. (1999) Electrical stimulation of the horizontal limb of the diagonal band of broca modulates population EPSPs in piriform cortex, J. Neurophysiology 81: 2737-2742. PDF
Patil, M.M. and Hasselmo, M.E. (1999) Modulation of inhibitory synaptic potentials in the piriform cortex. J. Neurophysiol. 81(5): 2103-2118. PDF
Linster, C and Hasselmo, M.E. (1999) Behavioral responses to aliphatic aldehydes can be predicted from electrophysiological responses of mitral cells in the olfactory bulb. Physiology and Behavior, 66(3): 497-502.
Fransen, E., Wallenstein, G.V., Alonso, A., Dickson, C.T. and Hasselmo, M.E. (1999) A biophysical simulation of intrinsic and network properties of entorhinal cortex. Neurocomputing 26-27: 375-380.
Knowles RB, Wyart C, Buldyrev SV, Cruz L, Urbanc B, Hasselmo ME, Stanley HE, Hyman BT (1999) Plaque-induced neurite abnormalities: implications for disruption of neural networks in Alzheimer's disease. Proc Natl Acad Sci U S A 96(9):5274-9.
Kwon JS, O'Donnell BF, Wallenstein GV, Greene RW, Hirayasu Y, Nestor PG, Hasselmo ME, Potts GF, Shenton ME, McCarley RW. (1999) Gamma frequency-range abnormalities to auditory stimulation in schizophrenia. Arch Gen Psychiatry. 56(11):1001-5.

1998


Wallenstein, G.V., Eichenbaum, H.B. and Hasselmo, M.E. (1998) The hippocampus as an associator of discontiguous events. Trends Neurosci. 21: 317-323. PDF
Sohal, V.S. and Hasselmo, M.E. (1998) Changes in GABAB modulation during a theta cycle may be analogous to the fall of temperature during annealing. Neural Computation, 10: 889-902. PDF
Patil, M.M., Linster, C., Lubenov, E. and Hasselmo, M.E. (1998) Cholinergic agonist carbachol enables associative long-term potentiation in piriform cortex slices. J. Neurophysiol. 80: 2467-2474. PDF
Sohal, V.S. and Hasselmo, M.E. (1998) GABAB modulation improves sequence disambiguation in computational models of hippocampal region CA3. Hippocampus 8:171-193.
Myers, C.E., Ermita, B.R., Hasselmo, M. and Gluck, M.A. (1998) Further implications of a computational model of septohippocampal cholinergic modulation in eyeblink conditioning. Psychobiol. 26: 1-20.

1997


Hasselmo, M.E., Linster, C., Ma, D. and Cekic, M. (1997) Noradrenergic suppression of synaptic transmission may influence cortical "signal-to-noise" ratio. J. Neurophysiol. 77: 3326-3339. PDF
Barkai, E., Hasselmo, M.E. (1997) Acetylcholine and associative memory in the piriform cortex. Mol Neurobiol. 15(1):17-29.
Hasselmo, M.E. and Wyble, B.P. (1997) Simulation of the effects of scopolamine on free recall and recognition in a network model of the hippocampus. Behav. Brain Res. 89: 1-34. PDF
Wallenstein, G.V. and Hasselmo, M.E. (1997a) GABAergic modulation of hippocampal activity: Sequence learning, place field development, and the phase precession effect. Journal of Neurophysiology, 78: 393-408. PDF
Hasselmo, M.E. (1997) A computational model of the progression of Alzheimer's disease. M.D. Computing 14: 181-191.
Wallenstein, G.V. and Hasselmo, M.E. (1997b) Functional transitions between epileptiform-like activity and associative memory in hippocampal region CA3. Brain Research Bulletin, 43: 485-493.
Linster, C., Hasselmo, M.E. (1997) Modulation of inhibition in a model of olfactory bulb reduces overlap in the neural representation of olfactory stimuli. Behav. Brain Res. 84: 117-127. PDF

1996


Hasselmo, M.E., Wyble, B.P. and Wallenstein, G.V. (1996) Encoding and retrieval of episodic memories: Role of cholinergic and GABAergic modulation in the hippocampus. Hippocampus, 6(6): 693-708. PDF
Hasselmo, M.E. and Cekic M. (1996) Suppression of synaptic transmission allows combination of associative feedback and self-organizing feedforward connections in a model of neocortex. Behav. Brain Res. 79: 153-161. PDF
Grunze, H.C.R., Rainnie, D.G., Hasselmo, M.E., Barkai, E., Heam, E.F., McCarley, R.W., Greene, R.W. (1996) NMDA-dependent modulation of CA1 local circuit inhibition. J. Neurosci. 16: 2034- 2043.
Tang, A.C. and Hasselmo, M.E. (1996) Effect of long-term baclofen treatment on recognition memory and novelty detection. Behav. Brain Res. 74: 145-152. PDF
Myers, C.E., Ermita, B.R., Harris, K., Hasselmo, M.E., Solomon, P. and Gluck, M.A. (1996) A computational model of cholinergic disruption of septo-hippocampal activity in classical eyeblink conditioning. Neurobiol. Learning and Memory, 66: 2034-2043.

1995


Hasselmo, M.E. (1995) Neuromodulation and cortical function: Modeling the physiological basis of behavior. Behav. Brain Res. 67: 1-27. PDF
Hasselmo, M.E., Schnell, E., Barkai, E. (1995) Dynamics of learning and recall at excitatory recurrent synapses and cholinergic modulation in hippocampal region CA3. J. Neurosci. 15(7): 5249-5262. PDF MATLAB script demonstrating model
Hasselmo, M.E. and Barkai, E. (1995) Cholinergic modulation of activity-dependent synaptic plasticity in rat piriform cortex. J. Neurosci. 15(10): 6592-6604. PDF
Liljenstrom H. and Hasselmo M.E. (1995) Cholinergic modulation of cortical oscillatory dynamics. J. Neurophysiol. 74: 288-297.

1994


Hasselmo, M.E. and Schnell, E. (1994) Laminar selectivity of the cholinergic suppression of synaptic transmission in rat hippocampal region CA1: computational modeling and brain slice physiology. J. Neurosci. 14(6): 3898-3914. PDF
Barkai E. and Hasselmo M.E. (1994) Modulation of the input/output function of rat piriform cortex pyramidal cells. J. Neurophysiol. 72: 644-658.
Barkai E., Bergman, R.E., Horwitz, G. and Hasselmo M.E. (1994) Modulation of associative memory function in a biophysical simulation of rat piriform cortex. J. Neurophysiol. 72: 659-677.
Hasselmo M.E. (1994) Runaway synaptic modification in models of cortex: Implications for Alzheimer╣s disease. Neural Networks 7(1): 13-40. PDF
Tang, A.C. and Hasselmo, M.E. (1994) Selective suppression of intrinsic but not afferent fiber synaptic transmission by baclofen in the piriform (olfactory) cortex. Brain Res. 659: 75-81.

1993


Hasselmo M.E. (1993) Acetylcholine and learning in a cortical associative memory. Neural Computation. 5(1): 32-44.
Hasselmo M.E. and Bower J.M. (1993) Acetylcholine and memory. Trends Neurosci. 16(6): 218-222. PDF

1992


Hasselmo M.E. and Bower J.M. (1992) Cholinergic suppression specific to intrinsic not afferent fiber synapses in rat piriform (olfactory) cortex. J. Neurophysiol. 67: 1222-1238.
Hasselmo M.E., Anderson B.P. and Bower J.M. (1992) Cholinergic modulation of cortical associative memory function. J. Neurophysiol. 67: 1239-1246.

1991


Hasselmo M.E. and Bower J.M. (1991) Selective suppression of afferent but not intrinsic fiber synaptic transmission by 2-amino-4-phosphonobutyric acid (AP4) in piriform cortex. Brain Research. 548: 248-255.

1990


Hasselmo M.E. and Bower J.M. (1990) Afferent and association fiber differences in short-term potentiation in piriform (olfactory) cortex of the rat. J. Neurophysiol. 64:179-190.

1989


Hasselmo M.E., Rolls E.T., Baylis G.C. (1989a) The role of expression and identity in the face-selective responses of neurons in the temporal visual cortex of the monkey. Behav. Brain Res. 32:203-218.
Hasselmo M.E., Rolls E.T., Baylis G.C., Nalwa V. (1989b) Object-centered encoding by face-selective neurons in the cortex in the superior temporal sulcus of the monkey. Exp. Brain Res. 75(2):417-429.
Rolls E.T., Baylis G.C., Hasselmo M.E., Nalwa V. (1989) The effect of learning on the face selective responses of neurons in the cortex in the superior temporal sulcus of the monkey. Exp. Brain Res. 76:153-164

1987


Rolls E.T., Baylis G.C., Hasselmo M.E. (1987) The responses of neurons in the cortex in the superior temporal sulcus of the monkey to band-pass spatial frequency filtered faces. Vision Res. 27:311-326.

BOOK AND JOURNAL EDITOR:


Wunsch, D.C., Hasselmo, M.E., Venayagamoorthy, G.K. and Wang, D. (2003) Advances in Neural Network Research. IJCNN 2003. Pergamon (Elsevier): Boston.
Doya, K., Dayan, P. and Hasselmo, M.E. (2002) Special issue: Computational Models of Neuromodulation. Neural Networks.
Touretzky, D.S., Mozer, M.C. and Hasselmo, M.E. (1996) Advances in Neural Information Processing Systems 8. MIT Press: Cambridge, MA.

BOOK CHAPTERS:


Michael E. Hasselmo (2011) Models of hippocampus. Scholarpedia, 6(5):1371
Hasselmo, M.E., Cannon, R.C. and Koene, R. (2002) A simulation of parahippocampal and hippocampal structures guiding spatial navigation of a virtual rat in a virtual environment: A functional framework for theta theory. In: Witter, M.P. and Wouterlood, F. (eds.) The Parahippocampal Region: Organization and Role in Cognitive Function. Oxford University Press: London. PDF
Hasselmo, M.E., Wyble, B.P. and Cannon, R.C. (2001) From spike frequency to free recall: How neural circuits perform encoding and retrieval. In: A. Parker, T.J. Bussey, E. Wilding (eds.) The Cognitive Neuroscience of Memory: Encoding and Retrieval. Psychology Press: London. PDF
Hasselmo, M.E. (2003) Theta theory: Requirements for encoding events and task rules explain theta phase relationships in hippocampus and neocortex. Proc. Intl Joint Conf. on Neural Networks, 2003. PDF
Gorchetchnikov, A. and Hasselmo, M.E. (2003) Timing of consecutive traveling pulses in a model of entorhinal cortex. . Proc. Intl Joint Conf. Neural Networks, 2003. PDF
Hasselmo, M.E. and Kapur, A. (2001) Modeling of large networks. In: E. DeSchutter (ed.) Computational Neuroscience: Realistic modeling for experimentalists. CRC Press: New York, pp. 289-316.
Hasselmo, M.E., Fransen, E., Dickson, C., Alonso, A. (2000) Computational modeling of entorhinal cortex. Ann. NY Acad. Sci. 911: 418-446.
Hasselmo, M.E. (1999) Neuromodulation and the hippocampus: memory function and dysfunction in a network simulation. Prog. Brain Res. 121: 3-18.
Hasselmo, M.E. (1999) Septal modulation of hippocampal activity: What is the function of the theta rhythm? In: R. Numan (ed.) The Behavioral Neuroscience of the Septal Region. Springer-Verlag: New York. pp. 92-114.
Hasselmo, M. E., Wyble, B.P., & Stern, C.E. (1998). A model of human memory based on the cellular physiology of the hippocampal formation. In R. W. Parks, D. S. Levine & D. L. Long (Eds.), Fundamentals of neural network modeling: Neuropsychology and cognitive neuroscience (pp. 299-329). Cambridge, MA: MIT Press.
Hasselmo, M.E. and Linster, C. (1998) Neuromodulation and memory function. In: P.S. Katz (ed.) Beyond Neurotransmission: The Role of Neuromodulation in Information Flow and Neuronal Circuit Flexibility. Oxford University Press, Oxford, U. K.
Fransen, E., Wallenstein, G.V., Alonso, A., Dickson, C.T. and Hasselmo, M.E. (1998) A biophysical simulation of intrinsic and network properties of entorhinal cortex. In: J.M. Bower (ed.) Neurocomputing: Proceedings of the Computational Neuroscience Conference, Elsevier.
Hasselmo, M.E. and Linster, C. (1998) Acetylcholine and frontal cortex "signal-to-noise" ratio. In: B.L. Miller and J. Cummings (eds.) The Human Frontal Lobes: Function and Disorders. Guilford Press: New York, pp. 139-158.
M. Petrides, J. McGaugh, M. Gluck, D. Schacter, F. Keil, A. Martin, L. Cahill, H. Eichenbaum, M. Hasselmo, J. Murre, C. Myers, B. Roozendaal, D. Simons, W.C. Smith, and C. Williams (1998) Learning and Memory: Systems. In M.J. Zigmond, F.E. Bloom, S.C. Landis, J.L. Roberts, L.R. Squire (eds.) Fundamental Neuroscience, Academic Press: New York.

Hasselmo, M.E. and Wyble, B.P. (1997) Does the spread of Alzheimer's disease neuropathology involve the mechanisms of consolidation? In: J.A. Reggia, E. Ruppin, R.S.Berndt (eds.) Neural Modeling of Brain and Cognitive Disorders. World Scientific Publishing, London, pp. 43-62.
Stern, C.E. and Hasselmo, M.E. (1997) Functional magnetic resonance imaging and computational modeling: An integrated study of hippocampal function. In: J.M. Bower (ed.) Computational Neuroscience: Trends in Research, 1997. Plenum Press: New York, pp. 859-865.
Hasselmo, M.E. and Linster, C. (1998) Modeling the piriform cortex. In P.S. Ulinski, E.G. Jones and A. Peters (eds.) Cerebral Cortex, Volume 13: Models of cortical circuits. Kluwer Academic: Plenum Press, New York, pp. 525-560.
Sohal, V.S. and Hasselmo, M.E. (1997) A model of changes in inferotemporal activity during a delayed-match-to-sample task. In: J.M. Bower (ed.) Computational Neuroscience: Trends in Research, 1997. Plenum Press: New York, 845-850.
Linster, C. and Hasselmo, M.E. (1997) Short term memory function in a model of the olfactory system. In J.M. Bower (ed.) Computational Neuroscience, Trends in Research, 1997. Plenum Press: New York.
Patil, M. , Linster, C. and Hasselmo, M.E. (1997) Cholinergic modulation of inhibitory synaptic transmission in the piriform cortex. In J.M.Bower, (ed.) Computational Neuroscience, Trends in Research, 1997. Plenum Press: New York, pp. 159-165.
Hasselmo, M.E. and Cekic, M. (1996) Cholinergic suppression of transmission may allow combined associative memory function and self-organization in the neocortex. In: Touretzky, D.S., Mozer, M.C. and Hasselmo, M.E. (eds.) Advances in Neural Information Processing Systems 8. MIT Press: Cambridge, MA, pp. 131-137.
Hasselmo, M.E. and Cekic, M. (1995) Modulation in the neocortex: Physiological mechanisms for self-supervised learning. In: J.M. Bower (ed.) Computation and Neural Systems, Vol. 4 Kluwer Academic Publishers: Norwell, MA.
Tang, A.C. and Hasselmo, M.E. (1996) To recognize the new, must one remember the old? -- GABAergic modulation and its computational and behavioral consequences. In: J.M. Bower (ed.) Computational Neuroscience, Academic Press: New York.
Hasselmo, M.E. and Stern, C.E. (1995) Linking LTP to network function: A simulation of episodic memory in the hippocampal formation. In M. Baudry and J. Davis (eds.) Long-term potentiation, Vol. 3. MIT Press, Cambridge, MA.
Hasselmo, M.E. (1995) Physiological constraints on models of behavior. In L. Niklasson, M.B. Boden (eds.) Current Trends in Connectionism. Lawrence Erlbaum Assoc.; Hillsdale, NJ, p. 15-32.
Hasselmo, M.E., Schnell, E., Berke, J. and Barkai, E. (1995) A model of the hippocampus combining self-organization and associative memory function. In G. Tesauro, D. Touretzky, T. Leen (eds.) Advances in Neural Information Processing Systems, Vol. 7. MIT Press: Cambridge, MA.
Hasselmo, M.E. and Schnell, E. (1994) Feedback regulation of cholinergic modulation and hippocampal memory function. In J.M. Bower (ed.) Computation and Neural Systems, Vol. 3. Kluwer Academic Publishers: Norwell, MA.
Hasselmo, M.E., Barkai, E., Horwitz, G. and Bergman R.E. (1993) Modulation of neuronal adaptation and cortical associative memory function. In F. Eeckman and J.M. Bower (eds.) Computation in Neurons and Neural Systems, Vol. 2. Kluwer Academic Publishers: Norwell, MA.
Liljenstrom H. and Hasselmo M.E. (1993) Acetylcholine and cortical oscillatory dynamics. In F. Eeckman and J.M. Bower (eds.) Computation and Neural Systems. Kluwer Academic Publishers: Norwell, MA.
Bergman, R.E., Vanier M., Horwitz, G., Bower J.M. and Hasselmo M.E. (1993) Cholinergic modulation of associative memory function in a realistic computational model of piriform cortex. In F. Eeckman and J.M. Bower (eds.) Computation and Neural Systems. Kluwer Academic Publishers: Norwell, MA, pp. 273-280.
Hasselmo M.E., Anderson B.P. and Bower J.M. (1991) Cholinergic modulation may enhance cortical associative memory function. In R.P. Lippman, J. Moody and D.S. Touretsky (eds.) Advances in Neural Information Processing Systems 3. Morgan Kaufmann, San Mateo, CA, pp. 46-52.
Hasselmo M.E., Wilson M.A., Anderson B. and Bower J.M. (1991) Associative memory function in piriform (olfactory) cortex: Computational modeling and neuropharmacology. In Cold Spring Harbor Symposium on Quantitative Biology: The Brain. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y., pp. 599-610.
Rolls E.T., Baylis G.C., Hasselmo M.E. and Nalwa V. (1987) The representation of information in the temporal lobe visual cortical areas of the macaque monkey. In J.J. Kulikowski, C.M. Dickinson and I.J. Murray (eds.) Seeing, Contour and Colour. Pergamon Press, New York.