Louis C. Gerstenfeld, PhD

Louis Gerstenfeld

Professor, Department Orthopaedic Surgery, Boston University School of Medicine Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Division of Graduate Medical Sciences Research Professor, Boston University School of Medicine, Department of Biochemistry (ME)

Professor, Department Orthopaedic Surgery, Boston University School of Medicine
Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Division of Graduate Medical Sciences
Research Professor, Boston University School of Medicine, Department of Biochemistry
(ME)

  • Areas of Interest Bone Histomorphometry, Cell Biology of Skeletal Tissues, Extracellular Matrix, Fracture Healing, Osteoporosis

Biography

My expertise is in the area of skeletal tissue biology. I have studied skeletal biology for more than 30 years and have broad knowledge across many areas in the field, including metabolic bone disease and orthopedic-related diseases. I have carried out numerous preclinical assessments of pharmacological compounds as they relate to safety and efficacy in the treatment of fracture and osteoporosis. I have expertise in skeletal tissue structure and the histomorphometric assessment of skeletal tissues. I was among the first four labs in the United States to develop in vitro osteoblast cultures and helped to establish the standard time dependent sequence of osteogenic differentiation in vitro. My laboratory also was one of four to initially isolate the proteins and clone the major extracellular matrix proteins of bone. I have served on the NIH IRG for Orthopedics, NASA review panels for skeletal tissue biology and the DOD review panels for orthopedic related research.

Affiliation: Affiliated Faculty (ME), Primary & Affiliated Faculty (ME)