James Galagan, Ph.D.

bme.profile.Galagan James

Associate Professor, Biomedical Engineering and Microbiology

Associate Professor, Biomedical Engineering and Microbiology

  • Primary Appointment Associate Professor, Biomedical Engineering and Microbiology
  • Education Ph.D., Computational Neuroscience, MIT
    B.S., Computer and Electrical Engineering, UC Davis
  • Additional Affiliations Associate Director, Systems Biology, National Emerging Infectious Diseases Laboratory
    Associate Director, Microbial Genome Analysis, Broad Institute
  • Areas of Interest Systems Biology, Infectious Diseases, Tuberculosis, Computational Biology, Genomics and Microbiology.
  • Research Areas Dr. Galagan’s research is focused on Systems Biology of microbial organisms, specficially Mycobacterium tuberculosis – the causative agent of tuberculosis – and the fungus Neurospora crassa. The Galagan Lab is an interdisciplinary group that combines computational biology, genomics, and experimental lab work. Specific interests and projects include:

    Using a genomics, computational modeling, and experimental systems-identification techniques to reconstruct the gene regulatory network of M. tuberculosis.
    Developing and experimentally validating computational models of microbial metabolism forM. tuberculosis and N. crassa.
    Using high-throughput sequencing and comparative sequence analysis to study the functional evolution of M. tuberculosis.
    Developing computational methods for genomic data analysis (including gene prediction, gene expression analysis, and polymorphism discovery)
    Developing experimental methods for microbial systems identification and analysis, drawing on electrical and mechanical systems identification methods.

Publications

Affiliation: Primary Faculty (BME)