Ahmad S. Khalil, Ph.D.

Associate Professor (BME)

Associate Professor (BME)

  • Primary Appointment Associate Professor, Department of Biomedical Engineering
  • Education B.S., Mechanical Engineering, Stanford University
    M.S., Ph.D., Mechanical Engineering, MIT
  • Additional Affiliations Associate Director, Biological Design Center (BDC)
    Co-Director, SB2 NIH/NIGMS T32 Training Program
    Visiting Scholar, Wyss Institute at Harvard University
    Faculty, Molecular Biology, Cell Biology & Biochemistry (MCBB)
    Faculty, Bioinformatics
  • Honors and Awards 2019 Dorf-Ebner Distinguished Faculty Fellow
    2017 PECASE Award
    2016 NIH New Innovator
    2016 DARPA Young Faculty Award
    2015 Hartwell Foundation Investigator
    2014 NSF CAREER Award
  • Areas of Interest Synthetic biology; systems biology; genetic circuits; epigenetics; laboratory evolution; technology development & automation; yeast prions
  • Research Areas My research team is interested in how molecular circuits enable core cellular functions, such as decision-making, computation, and epigenetic memory. We primarily develop synthetic biology approaches to interrogate the function and evolution of these cellular regulatory systems. Current studies focus on using synthetic biology to study and control eukaryotic transcriptional regulation, chromatin and epigenetic regulation, and functional protein aggregation systems. In parallel, we have invented new technologies, such as the “eVOLVER” platform, an automated DIY framework for growing and evolving cellular populations in the laboratory that makes it easy to scale to many parallel cultures and precisely configure the cellular growth conditions. Our broad goal is to gain integrated, quantitative understanding of how cellular phenotypes emerge from underlying regulatory networks, how these systems evolve, and how to predictively engineer them for biomedical applications.

Publications

Affiliation: Primary & Affiliated Faculty (BME)