Category: Spotlight Research

How Cells Remember

In new research published in Cell, Assistant Professor Ahmad ‘Mo’ Khalil, graduate student Minhee Park and colleagues engineered a fully synthetic epigenetic system to better understand, study, and control its behaviors. Using synthetic biology, they constructed molecular modules that mimic features of natural epigenetic systems and found that they were able to induce epigenetic activities in mammalian cells, such as storing cellular memory.

Antibiotic Resistance Without the Antibiotics

Antibiotic resistance is a global threat that leads to more than 23,000 deaths each year in the United States, according to the Centers for Disease Control. Over exposure to antibiotics has long been blamed, but Assistant Professor Mary Dunlop is flipping that idea on its head, finding that bacteria can also develop resistance without being exposed to antibiotics.