Fluorescence Endomicroscopy with Out-of-Focus Rejection

photo of Dr. MertzJerome Mertz, Ph.D.DSS_image2
Associate Professor – Biomedical Engineering
Boston University – College of Engineering

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Satish Singh, M.D.
Assistant Professor – Medicine
Boston University – School of Medicine
Boston Medical Center – Gastroenterology

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Objective: To develop a novel technique for obtaining high resolution fluorescence images using an optical fiber probe. The technique is based on the use of structured laser illumination (speckle pattern) to achieve out-of-focus background rejection, with the end goal being the development of a fluorescence endomicroscope.

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Biomicroscopy Lab