The department of Periodontology provides research opportunities to students who are enrolled in the Periodontology Specialty Certificate Program interfaced with either the Master of Science in Dentistry (MSD) and/or the Doctor of Science in Dentistry (DScD) in periodontology degrees. The MSD and DScD research endeavors involve patient based as well as clinically related basic science investigations. The research laboratory utilizes multidisciplinary approaches and state-of-the-art technologies combined with 2D and 3D cell, tissue and organ culture models including in vivo animal models to develop fundamental understanding of the principles of biological transformation in human health to disease state(s). Currently, the laboratory has several ongoing projects related to periodontology and craniofacial bone deficiencies. Studies are also pursued in the areas of periodontal/implant surgeries, bone augmentation/regeneration by tissue/biomaterial engineering, and orthodontic tooth movement using 2D cell cultures, live ex-vivo bone organ culture model systems and in vivo animal studies, in conjunction with the use of the piezoelectric knife.