News and Lectures

Past Seminars

Fall 2013

September 12, Distinguished Lecturer Seminar
“Expanding Chemical Diversity of Therapeutic RNAs”
Anastasia Khvorova, Ph.D.
Professor, RNA Therapeutic Institute, University of Massachusetts Medical School, Worcester, MA
Host:  Ruslan Afasizhev

September 17, Seminar
“Roles for Sugars, Proteins, and Lipids in the Structure of Cyst and Oocyst Walls”
John C. Samuelson, M.D., Ph.D.
Professor, Department of Molecular and Cell Biology, Boston University, Henry M. Goldman School of Dental Medicine
Host:  Carlos B. Hirschberg

September 24, Seminar
“New Mass Spectrometry-Based Strategies to Define Glycans and Glycoconjugates”
Catherine Costello, Ph.D.
William Fairfield Warren Distinguished Professor, Director, Mass Spectrometry Resource, Boston University School of Medicine
Host:  Carlos B. Hirschberg

September 26, Distinguished Lecturer Seminar
“Genetic Analysis of Extracellular Matrix Formation in the Developing Zebrafish”
Jonathan Gitlin, M.D.
Senior Scientist, Marine Biological Laboratory, Woods Hole, MA
Host:  Philip C. Trackman

October 8, Seminar
“NOD2: Gatekeeper of Inflammation and its Role in Atherosclerosis and Obesity”
Salomon Amar, DDS, Ph.D.
Director of the Center for Anti-Inflammatory Therapeutics, Professor of Molecular and Cell Biology, Professor of Periodontology, Boston University Henry M. Goldman School of Dental Medicine
Host:  Carlos B. Hirschberg

October 10, Distinguished Lecturer Seminar
“MicroRNA Regulation in Stem Cells and Cancer”
Richard Gregory, Ph.D.
Associate Professor, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Harvard Stem Cell Institute
Host:  Ruslan Afasizhev

October 22, Seminar
“Dynamics of the Antibody Repertoire Following Infection or Immunization”
Thomas B. Kepler, Ph.D.
Professor, Department of Microbiology, Boston University School of Medicine
Host:  Carlos B. Hirschberg

October 24, Distinguished Lecturer Seminar
“Smad-dependent BMP signaling through type 1A receptor in cranial neural crest cells alters their cell fate to chondrocytes to cause craniosynostosis”
Yuji Mishina, Ph.D.
Associate Professor, Dept. of Biologic and Materials Sciences, School of Dentistry, University of Michigan
Host:  Yoshiyuki Mochida

November 07, Distinguished Lecturer Seminar
“VEGF Targets the Tumor Cell: Stemness and EMT”
Arthur M. Mercurio, Ph.D.
Professor and Interim Chair, Department of Cancer Biology, University of Massachusetts Medical School
Host:  Maria A. Kukuruzinska

November 12, Seminar
“p300 HAT activity in Melanoma Development and Progression”
Rhoda M. Alani, M.D.
Herbert Mescon Professor and Chair, Department of Dermatology, Boston University School of Medicine
Host:  Carlos B. Hirschberg

December 3, Seminar
“Field Carcinogenesis Detection to Personalize Cancer Screening”
Hemant Kumar Roy, M.D.
Professor of Medicine, Chief, Section of Gastroenterology, Boston University School of Medicine
Host:  Miklos Sahin-Toth

December 10, Distinguished Lecturer Seminar
“Integrated Top-down Bottom-up platforms for saliva proteomics”
Massimo Castagnola, Ph.D.
Professor, Istituto di Biochimica e Biochimica Clinica, Facoltà di Medicina, Università Cattolica, Rome, Italy
Host:  Eva J. Helmerhorst

December 12, Distinguished Lecturer Seminar
“Tumor suppressor function of alpha-catenin in squamous cell carcinoma”
Valeri Vasioukhin, Ph.D.
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington
Host:  Maria Kukuruzinska

December 20, Faculty Candidate Seminar
“Regulation of Erythropoiesis by Long Noncoding RNAs and mRNA-Binding Proteins”
Wenqian Hu, Ph.D.
Senior Research Associate, the Lodish Lab, Whitehead Institute for Biomedical Research
Host: Phillip C. Trackman

Spring 2013

January 8, Seminar
“Controlling vesicle size, number and cargo during clathrin-mediated endocytosis”
Brigitte Ritter, Ph.D.
Assistant Professor, Department of Biochemistry, Boston University School of Medicine
Host:  Carlos B. Hirschberg

January 17, Distinguished Lecturer Seminar
“Diverse Roles for N-Glycans in Endoplasmic Reticulum Quality Control”
Daniel Hebert, Ph.D.
Professor, Department of Biochemistry and Molecular Biology, University of Massachusetts – Amherst
Host:  Carlos B. Hirschberg

January 22, Seminar
“Multiple activities of the respiratory syncytial virus polymerase at the viral promoters”
Rachel Fearns, Ph.D.
Associate Professor, Department of Microbiology, Boston University School of Medicine
Host:  Carlos B. Hirschberg

January 29, Seminar
“Building the tip of the Type III Secretion System Needle on Shigella flexneri: IpaD first”
Esther Bullitt, Ph.D.
Associate Professor, Department of Physiology and Biophysics, Boston University School of Medicine
Host:  Carlos B. Hirschberg

February 5, Seminar
“Biliary pancreatitis: a receptor mediated disease?”
George Perides, Ph.D.
Associate Professor, Department of Surgery, Tufts Medical Center
Host:  Miklos Sahin-Toth

February 12, Seminar
“Apoptsome structure and procaspase activation”
Christopher W. Akey, Ph.D.
Professor, Department of Physiology and Biophysics , Boston University School of Medicine 
Host:  Carlos B. Hirschberg

February 26, Distinguished Lecturer Seminar
“An introduction to CEL-lular genetics: Carboxyl-ester lipase in pancreatic disease”
Anders Molven, Ph.D.
Professor of Molecular Pathology, The Gade Institute, University of Bergen, Norway, Fulbright Visiting Scholar, Joslin Diabetes Center, Harvard Medical School,
Host:  Miklos Sahin-Toth

March 5, Seminar
“Programmable biology: circuits for programming eukaryotic transcription and cellular microenvironments”
Ahmad S. Khalil, Ph.D.
Assistant Professor, Department of Biomedical Engineering, Boston University
Host:  Carlos B. Hirschberg

March 19, Seminar
“New Insights in Cardiac Remodeling in Heart Failure”
Flora Sam, M.D.
Associate Professor, Whitaker Cardiovascular Institute, Boston University School of Medicine
Host:  Carlos B. Hirschberg

April 19, Distinguished Lecturer Seminar
“Ductal bicarbonate secretion, a potential target for pancreatitis treatment”
Viktoria Venglovecz, Ph.D.
Assistant Professor, Department of Pharmacology and Pharmacotherapy, University of Szeged, Hungary
Host:  Miklos Sahin-Toth

April 25, Distinguished Lecturer Seminar
“Regulating the supply of Pancreatic Digestive Enzymes for Secretion by Pancreatic Acinar Cells”
John A. Williams, M.D., Ph.D.
Professor, Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan
Host:  Miklos Sahin-Toth

Fall 2012

August 7, Faculty Candidate Seminar
“Genetic and chemical studies of RORgt, a critical regulator of pro-inflammatory cells”
Jun R. Huh, Ph.D.
Postdoctoral Fellow, New York University School of Medicine, Skirball Institute of Biomolecular Medicine, New York, N.Y.
Host:  David E. Levin

August 9, Faculty Candidate Seminar
“Cryptogenes and RNA Editing Machines”
Ruslan Aphasizhev, Ph.D.
Associate Professor of Microbiology and Molecular Genetics, Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine
Host:  David E. Levin

August 13, Faculty Candidate Seminar
“Innate immunity against HIV-1”
Felipe Diaz-Griffero, Ph.D.
Assistant Professor, Department of Microbiology and Immunology, Albert Einstein College of Medicine, N.Y.
Host:  David E. Levin

September 6, Distinguished Lecturer Seminar
“Minnelide: a novel therapy for pancreatic cancer”
Ashok K. Saluja, Ph.D.
Eugene C. and Gail V. Sit Chair in Pancreatic and Gastrointestinal Cancer Research, Professor and Vice Chair of Research Department of Surgery, University of Minnesota
Host:  Miklos Sahin-Toth

September 10, Faculty Candidate Seminar
“Regulation of Mitochondrial Gene Expression by Pentatricopeptide Repeat RNA Binding Proteins”
Inna Afasizheva, Ph.D.
Assistant Researcher, Department of Microbiology and Molecular Genetics, School of Medicine
University of California, Irvine,
Host:  David E. Levin

September 11, Distinguished Lecturer Seminar
“Intravital microscopy: a powerful tool to study the physio-pathology of the oral cavity (…and more)”.
Roberto Weigert, Ph.D.
Chief, Intracellular Membrane Trafficking Unit, Oral and Pharyngeal Cancer Branch, National Institute of Dental and Cranofacial Research, National Institute of Health, Bethesda, MD
Host:  Carlos B. Hirschberg

September 18, Seminar
“Parkinson’s disease and Huntington’s disease: Methods for Identifying Neuroprotective Pathways”
Richard H. Myers, Ph.D.
Director, Genome Science Institute, Professor of Neurology, Boston University School of Medicine
Host:  Carlos B. Hirschberg

September 20, Faculty Candidate Seminar
“Polo-like kinase 1: From Cell Biology to Cancer Biology”
Xiaoqi Liu, Ph.D.
Associate Professor, Department of Biochemistry and Center for Cancer Research, Purdue University, West Lafayette, IN
Host:  David E. Levin

September 27, Faculty Candidate Seminar
“Maintenance of Hematopoietic Stem Cells through regulation of Wnt and mTOR Pathways”
Jian Huang, M.D., Ph.D.
Research associate, Department of Medicine, Hematology and Oncology Division University of Pennsylvania
Host:  David E. Levin

October 2, Seminar
“Notch Regulation of Progenitor Cell Fate in the Lung Epithelium”
Wellington V. Cardoso, M.D., Ph.D.
Professor of Medicine and Pathology & Laboratory Medicine Director, Lung Development Program Boston University School of Medicine
Host:  Carlos B. Hirschberg

October 9, Seminar
“Inhibiting Inflammation in the Adipose Tissue via Ubiquitin Signaling”
Valentina Perissi, Ph.D.
Assistant Professor, Biochemistry Department, Boston University School of Medicine
Host:  Carlos B. Hirschberg

October 18, Distinguished Lecturer Seminar
“Control of EMT (Epithelial-Mesenchymal Transition) and Breast Cancer”
Gail E. Sonenshein, Ph.D.
Professor, Department of Biochemistry, Tufts University School of Medicine
Host:  Carlos B. Hirschberg

October 23, Seminar
“Biomaterials to detect and treat Cardiovascular Disease”
Joyce Y. Wong, Ph.D.
Associate Professor, Department of Biomedical Engineering, Boston University
Host:  Carlos B. Hirschberg

October 30, Seminar
“Insulin Resistance and Vascular Dysfunction: From the Community to the Endothelial Cell”
Naomi M. Hamburg, M.D.
Assistant Professor, Clinical Cardiology, Boston University School of Medicine
Host:  Carlos B. Hirschberg

November 1, Distinguished Lecturer Seminar
“Sequence and Chromatin Features of Transcription Factors Binding Sites in the Human Genome”
Zhiping Weng, Ph.D.
Director, Program in Bioinformatics and Integrative Biology, Professor of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA
Host:  Carlos B. Hirschberg

November 6, Seminar
“Nuclear Receptor and Toll-like Receptor Cross Regulation of HIV in Myeloid Cells”
Gregory Viglianti, Ph.D.
Associate Professor, Department of Microbiology, Boston University School of Medicine
Host:  Carlos B. Hirschberg

Friday, November 9, Special Seminar
Post-doctoral Candidate
“The Role of Cell Wall Proteins in Candida albicans Biofilm Formation”
Saranna Fanning, Ph.D.
Postdoctoral Research Scientist, Department of Biological Sciences, Carnegie Mellon University
Pittsburgh, PA
Host:  David E. Levin

November 29, Distinguished Lecturer Seminar
“The Flip Side of Vesicular Transport and Membrane Biogenesis”
Todd Graham, Ph.D.
Professor, Department of Biological Sciences, Vanderbilt University, Nashville, TN
Host:  Carlos B. Hirschberg

December 4, Seminar
“Terminal uridylation of small RNAs by Zcchc11/Tut4”
Mathew Jones, Ph.D.
Assistant Professor, Pulmonary Center, Boston University School of Medicine
Host:  Carlos B. Hirschberg

Spring 2012

January 5, Faculty Candidate Seminar
“Novel Chromatin Mechanisms Regulating Lifespan”
Weiwei Dang, Ph.D.
Instructor of Cell and Developmental Biology, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania,
Host:  David Levin

January 10, Distinguished Lecturer Seminar
“New Strategies for Diagnosis and Therapy of Mucopolysaccharidoses”
Jeffrey D. Esko, Ph.D.
Professor, Department of Cellular and Molecular Medicine, University of California, San Diego, School of Medicine
Host:  Carlos B. Hirschberg

January 12, Faculty Candidate Seminar
“The role of CRL4-Cdt2 ubiquitin ligase in cell cycle progression and genome stability”
Tarek Abbas, Ph.D.
Research Assistant Professor, Department of Biochemistry and Molecular Genetics, University of Virginia
Host:  David Levin

January 17, Seminar
“mTORC1 and Lipid Partitioning”
Konstantin Kandror, Ph.D.
Professor of Biochemistry, Department of Biochemistry, Boston University School of Medicine
Host:  Carlos B. Hirschberg

January 19, Faculty Candidate Seminar
“Golgi Biogenesis, Function, and Defects in Diseases”
Yanzhuang Wang, Ph.D.
Associate Professor, Department of Molecular, Cellular and Developmental Biology, University of Michigan
Host:  David Levin

January 26, Seminar
“Home Sweet Home: How Toxoplasma gondii Remodels its Intracellular Niches”
Carolina E. Caffaro, Ph.D.
Postdoctoral Fellow, Department of Microbiology and Immunology, Stanford University School of Medicine
Host:  Carlos B. Hirschberg

February 14, SEMINAR
“Pluripotent Stem Cell Modeling of Development and Disease”
Darrell Kotton, M.D.
Associate Professor of Medicine, Pulmonary Center, Boston University School of Medicine
Host:  Carlos B. Hirschberg

February 21, Seminar
“Cellular Factors that Regulate HIV Latency”
Andrew J. Henderson, Ph.D.
Associate Professor, Department of Medicine, Boston University School of Medicine
Host:  Carlos B. Hirschberg

February 23, Distinguished Lecturer Seminar
“Genetic control of Candida albicans biofilm formation”
Aaron P. Mitchell, Ph.D.
Professor of Biological Sciences, Director, HHMI Undergraduate Science Education Program, Carnegie Mellon University
Host:  David E. Levin

February 28, Seminar
“Exploring New Paradigms of Trimeric G Protein Signaling in Motility, Metastasis and Autophagy”
Mikel Garcia-Marcos, Ph.D.
Assistant Professor, Department of Biochemistry, Boston University School of Medicine
Host:  Carlos B. Hirschberg

March 5, Special Seminar
“Regulation of Stress-induced Gene Expression by Control of Transcriptional Attenuation”
Ki-Young Kim, Ph.D.
Senior Postdoctoral Associate, Department of Molecular & Cell Biology, Henry M. Goldman School of Dental Medicine, Boston University
Host:  David E. Levin

March 6, Seminar
“The role of the AhR (aryl hydrocarbon receptor), an environmental chemical receptor, in mammary tumorigenesis: The AhR comes of age”
David Sherr, Ph.D.
Professor, Environmental Health, Boston University School of Public Health and
Pathology and Laboratory Medicine, Boston University School of Medicine
Host:  Carlos B. Hirschberg

March 15, Distinguished Lecturer Seminar
“Antigenic Variation in Malaria, a Tale of Tails”
Kirk W. Deitsch, Ph.D.
Professor, Microbiology and Immunology Department, Weill Medical College, Cornell University
Host:  John C. Samuelson

March 20, Seminar
“Using femtosecond lasers to study neuronal damage and regeneration in C. elegans”
Christopher V. Gabel, Ph.D.
Assistant Professor, Department of Physiology and Biophysics, Photonics Center, BUSM
Host:  Carlos B. Hirschberg

March 29, Distinguished Lecturer Seminar
“Adhesion and signaling through the cadherin/catenin system”
Cara J. Gottardi, Ph.D.
Assistant Professor, Department of Medicine, Northwestern University, Chicago
Host:  Maria A. Kukuruzinska

April 03, 2012, Seminar
“Next Generation Sequencing Studies in Neurodegenerative Diseases”
Richard H. Myers, PhD
Professor of Neurology, Director, Genome Science Institute, Boston University School of Medicine

April 5, Distinguished Lecturer Seminar
“Master Transcriptional Regulators of the Acinar Cell Phenotype”
Raymond MacDonald, Ph.D.
Professor, Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas
Host:  Maria Kukuruzinska

April 12, Distinguished Lecturer Seminar
“Protein kinase C delta: A switch between cell death and cell survival”
Mary Reyland, Ph.D.
Professor, Department of Craniofacial Biology, University of Colorado School of Dental Medicine
Host:  Maria Kukuruzinska

April 17, Special Seminar
“Survival without telomeres: The new role of Rif1 in checkpoint adaption”
Yuan Xue, Ph.D.
Postdoctoral Fellow, Crucible Lab, Centre for Life, Newcastle-upon-Tyne, United Kingdom
Host:  David E. Levin

April 19, Distinguished Lecturer Seminar
“Tumor Protein D52 (TP52) controls trafficking within a unique lysosome-like secretory pathway to remove activated proteases in pancreatic acinar cells”
Guy Groblewski, Ph.D.
Associate Professor, Department of Nutritional Sciences, University of Wisconsin-Madison
Host:  Miklos Sahin-Toth

May 14, Special Distinguished Lecturer Seminar
“Derangement of Bicarbonate Secretion in Pancreatitis”
Peter Hegyi, M.D., Ph.D., D.Sci.
Professor, First Department of Medicine, University of Szeged, Hungary
Host:  Miklos Sahin-Toth

June 29, Distinguished Lecturer Seminar
“mRNA trafficking and cell physiology: Getting the message”
Jeffrey E. Gerst, Ph.D.
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel
Host:  David E. Levin

Fall 2011

SEMINAR, Tuesday, September 20, 2011
“DNA Shape and the Workings of the Human Genome”
Tom Tullius, PhD
Professor, Department of Chemistry, Boston University

DISTINGUISHED LECTURER SEMINAR, Friday, September 23, 2011
“Captain Kaback and the Great White Permease”
H. Ronald Kaback, MD
Distinguished Professor, Department of Physiology, University of California, Los Angeles

SEMINAR, Tuesday, September 27, 2011
“Illuminating Paramyxoviruses: Attenuation and Pathogenesis, Two Sides of One Coin”
Paul Duprex, PhD
Associate Professor, Department of Microbiology, National Emerging Infectious Diseases Laboratories, Boston University School of Medicine

SEMINAR, Tuesday, October 11, 2011
“Obesity as a Chronic Inflammatory State: Is Adipose Tissue a Culprit?”
Susan K. Fried, PhD
Professor, Department of Medicine, Section of Endocrinology, Diabetes & Nutrition, Boston University School of Medicine

DISTINGUISHED LECTURER SEMINAR, Thursday, October 13, 2011
“GPI, Sphingolipids and Secretion: The molecular basis of virulence in African trypanosomes”
James D. Bangs, PhD
Professor, Department of Medical Microbiology and Immunology, University of Wisconsin—Madison

SEMINAR, Tuesday, October 18, 2011
“Evolution of Specificity in a Superfamily of Phosphatases”
Karen N. Allen, PhD
Professor, Department of Chemistry, Boston University

DISTINGUISHED LECTURER SEMINAR, Thursday, October 20, 2011
“The Fat-regulating Phosphatidic Acid Phosphatase Plays a Key Role in Protection against Lipotoxicity”
George M. Carman, PhD
Director, Rutgers Center for Lipid Research, Rutgers University, New Brunswick, N.J.

DISTINGUISHED LECTURER SEMINAR, Friday, October 21, 2011
“An abundant and unusual RNAi pathway regulates robust gene silencing in Entamoeba histolytica”
Upinder Singh, MD
Division Chief, Infectious Diseases and Geographic Medicine
Associate Professor, Departments of Internal Medicine and Microbiology and Immunology, Stanford University School of Medicine

SEMINAR, Tuesday, October 25, 2011
“Analysis and Design of Receptor-Ligand Interactions by Computational Mapping of Macromolecules”
Sandor Vajda, PhD
Professor, Department of Biomedical Engineering, Boston University

SEMINAR, Tuesday, November 01, 2011
“Early Events in the Assembly of Very Low Density Lipoprotein, the Precursor of LDL”
C. James McKnight, PhD
Associate Professor, Department of Physiology & Biophysics, Boston University School of Medicine

DISTINGUISHED LECTURER SEMINAR, Thursday, November 03, 2011
“Integration of Metabolism and Virulence in Gram-Positive Bacteria”
Abraham L. Sonenshein, PhD
Professor and Acting Chair, Department of Molecular Biology and Microbiology, Tufts University School of Medicine

SEMINAR, Tuesday, November 8, 2011
“Strategies for translating the mechanisms of androgen action into selective function promoting anabolic therapies”
Shalender Bhasin, MD
Professor of Medicine, Chief Section Endocrinology, Diabetes & Nutrition, Boston University School of Medicine

DISTINGUISHED LECTURER SEMINAR, Thursday, November 10, 2011
“Telomeres and Virulence Genes in Candida glabrata”
Brendan Cormack, PhD
Professor, Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine

SEMINAR, Tuesday, November 29, 2011
“Genetic Dissection of Host Resistance to Respiratory Infections”
Igor Kramnik, PhD
Associate Professor of Medicine & Microbiology, Boston University School of Medicine

FACULTY CANDIDATE SEMINAR, Wednesday, November 30, 2011
“Insulin Biosynthesis during the Development and Progression of Diabetes: A Double Edged Sword”
Ming Liu, MD, PhD
Research Assistant Professor, Division of Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan Medical School

DISTINGUISHED LECTURER SEMINAR, Thursday, December 1, 2011
“The PI3K-mTOR Signaling Circuitry and Novel Targeted Cancer Therapies and Preventive Strategies”
Silvio Gutkind, PhD
Chief, Oral and Pharyngeal Cancer Branch, NIDCR, NIH, Bethesda, Md.

FACULTY CANDIDATE SEMINAR, Tuesday, December 6, 2011
“Mechanisms of nervous system and muscle development and regeneration”
Laura N. Borodinsky, PhD
Assistant Professor, Department of Physiology & Membrane Biology, University of California, Davis, School of Medicine

DISTINGUISHED LECTURER SEMINAR, Thursday, December 8, 2011
“Defining Mammalian Host Cell Pathways that Support Intracellular Trypanosoma cruzi Infection: Is there Therapeutic Potential?”
Barbara A. Burleigh, PhD
Associate Professor, Department of Immunology and Infectious Diseases, Harvard School of Public Health

FACULTY CANDIDATE SEMINAR, Thursday, December 15, 2011
“Regulation of the DLK-1 pathway in synapse formation and axon regeneration”
Dong Yan, PhD
Post-doctoral Fellow, Division of Biological Sciences, University of California, San Diego