OCRI News

OCRI Hosts Second External Advisory Board Meeting

February 20th, 2014 in Oral Cancer Research Initiative.

The Oral Cancer Research Initiative hosted its second External Advisory Board (EAB) meeting on November 21-22, 2013, at the Hotel Commonwealth. The Board members in attendance were Dr. Thomas Glynn from the American Cancer Society, Dr. Jennifer Grandis from the University of Pittsburgh, Dr. Bruce Johnson from the Dana-Farber Cancer Institute, Dr. Dong Shin from Emory University and Dr. Gregory Wolf from the  University of Michigan. The purpose of the meeting was to present an update on the progress of the OCRI since the last Board meeting in November 2012, and to solicit advice on the development of a competitive SPORE... More

OCRI’s Application for Evans Center for Interdisciplinary Biomedical Research Affinity Research Collaborative Funding Successful

February 20th, 2014 in Oral Cancer Research Initiative.

We are delighted to report that the OCRI’s submission to the Evans Center for Interdisciplinary Biomedical Research for funding was successful. As a result, a number of OCRI researchers will continue to collaborate on the OCRI ARC. The OCRI pre-ARC was formed in 2012 and submitted an application for funding in November 2013. The ARC is co-funded by the Evans Center for Interdisciplinary Biomedical Research and the Boston University Henry M. Goldman School of Dental Medicine. There are a number of ARCs on the medical campus, each consisting of approximately 5 to 8 investigators who focus on a research theme, explored... More

Researcher Spotlight: Manish Bais, DVM, PhD

February 20th, 2014 in Oral Cancer Research Initiative.

Dr. Manish Bais is a Research Assistant Professor in the Department of Molecular and Cell Biology at Boston University’s Henry M. Goldman School of Dental Medicine. Dr. Bais is also an important member of the Oral Cancer Research Initiative (OCRI). With funding from the OCRI, Dr. Bais travelled to the National Institute of Dental and Craniofacial Research in the summer of 2013 to receive mouse model training in the lab of Dr. Roberto Weigert.  Dr. Bais has made large contributions to the initiative with the development of an orthotropic oral cancer mouse model. The orthotropic nude mouse models of non-metastatic and... More

History of Oral Cancer Research Initiative

November 22nd, 2013 in Oral Cancer Research Initiative.

Head and neck cancer represents the sixth most common cancer in the world, with oral cancer accounting for the majority of cases. From about 40,000 people diagnosed with oral cancer each year about 8,000 will die from the disease. Worldwide, new cases exceed 640,000 annually and their incidence is on the rise. Unlike other cancers, the statistics on oral cancer are startlingly sinister: half of oral cancers are not diagnosed until the cancer has spread to nearby tissues, at which stage the 5-year survival rate is 53 percent. Further, treatments used at later stage diagnosis are often painful and include disfiguring... More

OCRI Expands to Include Collaboration with Dana-Farber Cancer Institute

November 22nd, 2013 in Oral Cancer Research Initiative.

The Oral Cancer Research Initiative was launched in November 2011 and has continually expanded to include a diverse group of researchers and clinicians from throughout the Boston University community. As the initiative developed, it became clear that in order to maximize our potential we needed to ensure that we had access to an adequate head and neck cancer population to support our translational research objectives. Moreover, it was evident that the initiative would benefit from strong clinical input from head and neck cancer clinical leaders who would be best positioned to push translational approaches. To facilitate enhanced collaboration with clinicians... More

OCRI Researchers Form Pre-ARC

November 22nd, 2013 in Oral Cancer Research Initiative.

The Oral Cancer Research Initiative was invited by Dr. Katya Ravid, Director of the Evans Center for Interdisciplinary Biomedical Research, to form a pre-ARC. Pre-ARCs serve as an intermediate phase of exploration of research themes before becoming a formal ARC (Affinity Research Collaborative). The pre-ARC is titled Etiology and Pathogenesis of Oral Cancer (EPOC) and the Directors are Maria Kukuruzinska, Avi Spira and Maria Trojanowska. The EPOC pre-ARC is a multidisciplinary collaboration involving a subset of OCRI researchers. As such, EPOC meets the major goal of the ARC program of “…focusing on a research theme, explored with the aid of different... More