The National Institutes of Health (NIH)


Research (R, P, D and U Announcements)

Title (Activity Code) Deadline Announcement Number
National Dental Practice-Based Research Network Clinical Trial or Observational Study Planning and Implementation Cooperative Agreement (UG3/UH3 Exploratory/Developmental Phased Award Cooperative Agreement) October 7 2022; February 9 2023, June 9, 2023 PAR-20-306
Health Services Research on Minority Health and Health Disparities (R01 Research Project Grant) November 17 2022; February 17, 2023 PAR-20-310
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Research Project Grant) January 26, 2023; May 26, 2023; September 26, 2023 PAR-21-038
Improving oral health and reducing disparities in adolescents (R01 Research Project Grant) February 5, June 5, October 5 PAR-20-058
NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Small Grant Program) February 16, June 16, October 16 PAR-20-046
Improving oral health and reducing disparities in adolescents (R21 Exploratory/Developmental Research Grant) February 16, June 16, October 16 PAR-20-059
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Research Project – Cooperative Agreements) February 5, June 5, October 5 PAR-20-060
Notice of Special Interest (NOSI): NIDCR Support for Research on the Physiological Involvement of Oral Cavity in Coronavirus Disease 2019 (COVID-19) Beginning June 5, 2021 NOT-DE-21-001
NIH Research Project Grant (R01 Research Grant) February 5, June 5, October 5 PA-20-185
NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Small Grant Program) February 16, June 16, October 16 PA-20-046
NIH Exploratory/Developmental Research Grant Program (R21 Research Grant) February 16, June 16, October 16 PA-20-195
NIH Support for Conferences and Scientific Meetings (R13) April 12, August 12, December 12 PA-21-151
Using Innovative Digital Healthcare Solutions to Improve Quality at the Point of Care (R21/R33 Phased Innovation Award) February 16, June 16, October 16 PA-21-164
NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00 Pre-doc to Post-doc Transition Award/Post-doctoral Transition Award) February 12, June 12, October 12 PAR-21-060
Notice of Special Interest: Administrative Supplements to Support Dentist Scientists Post Specialty or Residency to Develop Expertise in Dental, Oral and Craniofacial Research Varies NOT-DE-20-035
Notice of Special Interest (NOSI): Simulation Modeling and Systems Science to Address Health Disparities Varies NOT-MD-20-025
Innovative Research in Cancer Nanotechnology (IRCN) (R01 Research Project Grant) Varies PAR-20-284
Notice of Special Interest (NOSI) of NIDCR in Supporting Dental, Oral, and Craniofacial Research Using Bioinformatic, Computational, and Data Science Approaches Varies NOT-DE-20-006
Enabling Technologies to Accelerate Development of Oral Biodevices (R21 Research Grant) February 16, June 16, October 16 PAR-20-232
Enabling Technologies to Accelerate Development of Oral Biodevices (R01 Research Grant) February 5, June 5, October 5 PAR-20-233
Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Research Project Grant) February 5, June 5, October 5 PAR-20-131
Biomedical Data Repository (U24 Resource-Related Research Projects – Cooperative Agreements) January 25, September 25 PAR-20-089
National Cancer Institute Program Project Applications (P01 Research Program Projects) January 25, May 25, September 25 PAR-20-077
Improving oral health and reducing disparities in adolescents (R01) February 5, June 5, October 5 PAR-20-058
Improving oral health and reducing disparities in adolescents (R21) February 16, June 16, October 16 PAR-20-059
NIDCR Small Grant Program for New Investigators (R03 Small Grant Program) February 16, June 16, October 16 PAR-21-084

Training (K Announcements)

Title (Activity Code) Deadline Announcement Number
Mentored Research Scientist Development Award (K01 Training Grant) February 12, June 12, October 12 PA-20-190
Mentored Quantitative Research Development Award (K25 Training Grant) March 12, July 12, November 12 PA-20-199
NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00 F99/K00 Individual Predoctoral to Postdoctoral Transition Award) February 12, June 12, October 12 PAR-20-069
NIDCR Small Grant Program for New Investigators (R03 Small Grant Program) February 16, June 16, October 16 PAR-21-084
NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00 Pre-doc to Post-doc Transition Award/Post-doctoral Transition Award) February 12, June 12, October 12 PAR-21-060
NIDCR Dual Degree Dentist Scientist Predoctoral to Postdoctoral Transition Award (F99/K00 Pre-doc to Post-doc Transition Award/Post-doctoral Transition Award) February 12, June 12, October 12 PAR-21-108

Research (R, P, D and U Announcements)

 

Title: National Dental Practice-Based Research Network Clinical Trial or Observational Study Planning and Implementation Cooperative Agreement (UG3/UH3 Exploratory/Developmental Phased Award Cooperative Agreement)
Announcement Number: PAR-20-306
Deadline: June 9, 2021, and October 8 2021; February 9, 2022, June 9, 2022, and October 7 2022; February 9 2023, June 9, 2023
Purpose: The National Institute of Dental and Craniofacial Research (NIDCR) is continuing support for research conducted within a dental Practice-Based Research Network (PBRN). The National Dental PBRN Administrative and Resource Center and National Coordinating Center support the infrastructure for and implementation of multiple observational studies and clinical trials. This Funding Opportunity Announcement (FOA) is soliciting applications for clinical trials and large clinical observational studies to be conducted in the National Dental PBRN through a milestone-driven UG3/UH3 cooperative agreement mechanism. Each UG3/UH3 award will support an individual project which will utilize the National Dental PBRN infrastructure and resources for study planning and implementation. This FOA supports a UG3 clinical study planning phase and potential transition to a UH3 implementation phase. Progression to the UH3 phase is based on an administrative review and is dependent on success in meeting UG3 milestones, consideration of the dental PBRN as an appropriate venue for conduct of the research, NIDCR program priorities, and availability of funds.
The main goals of the dental PBRN are to streamline the implementation of national oral health research studies in dental practices on topics of importance to practitioners and their patients, to provide evidence useful in daily patient care, and to facilitate the translation of research findings into clinical practice. This FOA encourages applications proposing research studies that align with the goals of the dental PBRN.
Award: The UG3 phase is limited to a total of $275,000 in direct costs over the entire UG3 phase. Application budgets for the UH3 phase are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: September 08, 2023


Title: Health Services Research on Minority Health and Health Disparities (R01 Research Project Grant)
Announcement Number: PAR-20-310
Deadline: November 17, 2021; March 17, 2022; November 17 2022; February 17, 2023
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to encourage innovative health services research that can directly and demonstrably contribute to the improvement of minority health and/or the reduction of health disparities at the health care system-level as well as within clinical settings.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires:  March 28, 2023


Title: Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Research Project Grant)
Announcement Number: PAR-21-038
Deadline: May 26, 2021; September 28, 2021; January 26, 2022; May 26, 2022; September 27, 2022; January 26, 2023; May 26, 2023; September 26, 2023
Purpose: The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project that represents a change in research direction for an early stage investigator (ESI) and for which no preliminary data exist. Applications submitted to this Funding Opportunity Announcement (FOA) must not include preliminary data. Applications must include a separate attachment describing the change in research direction. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions. This Funding Opportunity Announcement does not accept applications proposing clinical trials.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires:  December 29, 2023


Title: Improving oral health and reducing disparities in adolescents (R01 Research Project Grant)
Announcement Number: PAR-20-058
Deadline: February 5, June 5, October 5
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to stimulate research to improve the oral health of adolescents in the United States, and to reduce observed oral health disparities and inequities in this population. This FOA defines “adolescents” as those individuals between the ages of 10 and 19.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: January 08, 2023


Title: NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Small Grant Program)
Announcement Number: PA-20-046
Deadline: February 16, June 16, October 16
Purpose: The purpose of this FOA is to announce support for meritorious research projects that address research questions relevant to human dental, oral, or craniofacial (DOC) conditions or traits through analysis of existing and publicly available genomics data using statistical and computational approaches. Data analysis for each project can be performed using existing and/or novel methods to be developed in the same project, including machine learning-based methods (ML).
Award: The combined budget for direct costs for the two year project period may not exceed $200,000. No more than $200,000 direct costs may be requested in any single year.
Eligibility & Guidelines: Here
Announcement Expires: January 08, 2023


Title: Improving oral health and reducing disparities in adolescents (R21 Exploratory/Developmental Research Grant)
Announcement Number: PA-20-059
Deadline: February 16, June 16, October 16
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to encourage exploratory or developmental research to improve the oral health of adolescents in the United States, and to reduce observed oral health disparities and inequities in this population. This FOA defines “adolescents” as those individuals between the ages of 10 and 19.
Award: The combined budget for direct costs for the two year project period may not exceed $275,000. No more than $200,000 direct costs may be requested in any single year.
Eligibility & Guidelines: Here
Announcement Expires: January 08, 2023


Title: NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Research Project – Cooperative Agreements)
Announcement Number: PA-20-060
Deadline: February 5, June 5, October 5
Purpose: This Funding Opportunity Announcement (FOA) will support, through the cooperative agreement mechanism, investigator-initiated observational studies or biomarker validation studies that require prospective collection of data/biospecimens or continued analysis of data/biospecimens collected as part of a previous NIDCR award.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project. A project duration of up to five years may be requested.
Eligibility & Guidelines: Here
Announcement Expires: January 10, 2023


Title: Notice of Special Interest (NOSI): NIDCR Support for Research on the Physiological Involvement of Oral Cavity in Coronavirus Disease 2019 (COVID-19)
Announcement Number: NOT-DE-21-001
Deadline: Beginning June 05, 2021
Purpose: The National Institute of Dental and Craniofacial Research (NIDCR) is issuing this Notice of Special Interest (NOSI) to encourage research studies focused on the physiological involvement of oral cavity and oral manifestations related to SARS-CoV-2 and/or Coronavirus Disease 2019 (COVID-19).
Globally, the death toll for COVID-19 caused by the coronavirus SARS-CoV-2 has surpassed 1.9 million, and in the United States, more than 375,000 individuals have succumbed to the disease as of January 2021. Synergizing with a myriad of initiatives across NIH and responding to a palpable sense of public health urgency, NIDCR is positioned to address COVID-19 research knowledge gaps unique to our mission, as well as to facilitate broad and rapid dissemination of research findings. Outcomes from this NOSI are expected to strengthen the knowledge base of COVID-19 disease mechanisms and presentations in the oral cavity.
Eligibility & Guidelines: Here
Announcement Expires: May 08, 2023


Title: NIH Research Project Grant (R01 Research Grant)
Announcement Number: PA-20-185
Deadline: February 5, June 5, October 5
Purpose: The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: May 08, 2023


Title: NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Small Grant Program)
Announcement Number: PA-20-046
Deadline: February 16, June 16, October 16
Purpose: The purpose of this FOA is to announce support for meritorious research projects that address research questions relevant to human dental, oral, or craniofacial (DOC) conditions or traits through analysis of existing and publicly available genomics data using statistical and computational approaches. Data analysis for each project can be performed using existing and/or novel methods to be developed in the same project, including machine learning-based methods (ML).
Award: The combined budget for direct costs for the two year project period may not exceed $200,000. No more than $200,000 direct costs may be requested in any single year.
Eligibility & Guidelines: Here
Announcement Expires: January 08, 2023


Title: NIH Exploratory/Developmental Research Grant Program (R21 Research Grant)
Announcement Number: PA-20-195
Deadline: February 16, June 16, October 16
Purpose: The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.
Award: The combined budget for direct costs for the two-year project period may not exceed $275,000. No more than $200,000 may be requested in any single year.
Eligibility & Guidelines: Here
Announcement Expires: May 08, 2023


Title: NIH Support for Conferences and Scientific Meetings (R13)
Announcement Number: PA-21-151
Deadline: April 12, August 12, December 12
Purpose: The purpose of the NIH Research Conference Grant (R13) is to support high quality conferences that are relevant to the public health and to the scientific mission of the participating Institutes and Centers.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project. The appropriate NIH Conference Grant Contact should be consulted for guidance regarding any IC-specific budget limitations.
Eligibility & Guidelines: Here
Announcement Expires: January 08, 2024


Title: Using Innovative Digital Healthcare Solutions to Improve Quality at the Point of Care (R21/R33 Phased Innovation Award)
Announcement Number: PA-21-164
Deadline: February 16, June 16, October 16
Purpose: The Agency for Healthcare Research and Quality’s (AHRQ) mission is to produce evidence to make health care safer, of higher quality, more accessible, equitable, and affordable, and to work within the U.S. Department of Health and Human Services and with other partners to make sure that the evidence is understood and used. This FOA invites applications that propose research projects that test promising digital healthcare interventions aimed at improving quality of care and healthcare services delivery at the point of care. This FOA will use the Phased Innovation Award (R21/R33) mechanism to provide up to 2 years of R21 support for initial developmental activities, and up to 3 years of R33 support for expanded activities. Transition to the R33 phase is not guaranteed for all grants awarded under this FOA. Continuation from the R21 phase to the R33 phase will be determined by AHRQ staff based on progress achieved in the R21 phase and factors such as program priorities and availability of funds.
Award: In the R21 phase, the combined budget for total costs (direct and indirect) for the two-year period may not exceed $275,000. No more than $200,000 total costs may be budgeted in either year of the R21 phase. In the R33 phase, the combined budget for total costs (direct and indirect) for the three-year period may not exceed $750,000. No more than $300,000 total costs may be budgeted in any given year.
Eligibility & Guidelines: Here
Announcement Expires: July 18, 2024


Title: NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00 Pre-doc to Post-doc Transition Award/Post-doctoral Transition Award)
Announcement Number: PAR-21-060
Deadline: February 12, June 12, October 12
Purpose: The purpose of the NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00) is to support outstanding graduate students from diverse backgrounds, including those from groups underrepresented in biomedical, clinical, behavioral and social sciences, over the transition from predoctoral to postdoctoral research training. This phased award program will facilitate completion of graduate PhD or dual degree clinician scientist programs (F99) and progression to mentored postdoctoral positions in dental, oral and craniofacial research (K00). It is anticipated that successful completion of this phased award program will enable achievement of an independent research faculty position and subsequent NIDCR career development and research project awards.
Award: For the F99 phase, award budgets are composed of stipends, tuition and fees, and institutional allowance, as described below. For the K00 phase, award budgets are composed of salaries and fringe benefits, research and career development support, and indirect costs, as described below. For the F99/K00 award, individuals may receive up to 5 years combined support for both phases, which includes up to 2 years in the F99 fellowship phase and up to 3 years in the K00 career development phase.
Eligibility & Guidelines: Here
Announcement Expires: January 08, 2024


Title: Notice of Special Interest: Administrative Supplements to Support Dentist Scientists Post Specialty or Residency to Develop Expertise in Dental, Oral and Craniofacial Research
Announcement Number: NOT-DE-20-035
Deadline: Varies
Purpose: The purpose of the NIDCR Dentist Scientist Administrative Supplement Program is to enhance the research careers of dentist-scientists who can contribute vital clinical perspectives to dental, oral and craniofacial research projects, and to build and sustain a dentist-scientist research workforce dedicated to improving dental, oral and craniofacial health. The program will provide supplemental funds to active NIDCR research grants to support mentored research experiences for outstanding early career dentist-scientists who have recently completed dental specialty or residency training. The program is intended to accelerate the candidate’s transition from primarily clinical activities to predominantly research activities by providing protected time to develop or update research skills, formulate a research career plan, generate preliminary data and seek independent funding. Dentist scientist candidates for this program are expected to contribute substantially to on-going research by conducting well-defined projects that are within scope of the goals and objectives of the parent grant. The candidate’s research experience is expected to be guided by an experienced investigator(s) and provide a foundation for the candidate’s future research independence. Mentors are expected to work with candidates to develop research experience plans that include the preparation of an independent grant application for NIDCR support and are anticipated to enhance the candidate’s successful competition for independent research support. An initial request for one year of supplement support will be allowed, with the expectation that the candidate will make research progress and begin preparation of a grant application. An application for a second consecutive year of supplement support will be considered if progress in the initial year is demonstrated, and the need for an additional year of support to achieve the proposed career development goals and submission of an application for an independent support is strongly justified.
Award: The NIDCR will provide support for the candidate’s annual salary, in accordance with the salary structure of the grantee institution, and consistent with the level of effort, up to $100,000 per year plus allowable fringe benefits. The total salary requested for the candidate must be established on the base salary of a full-time, 12-month staff appointment. The supplement budget may request up to $25,000 per year for additional research-related costs such as laboratory supplies and core services, as well as costs for the candidate’s travel to a scientific conference. The duration of an initial supplement request must be one year. The parent award must have at least one year, or two or more years remaining on the project period at the time of supplement award. Two or more years would allow a potential second supplement application.
Eligibility & Guidelines: Here
Announcement Expires: July 24, 2023


Title: Notice of Special Interest (NOSI): Simulation Modeling and Systems Science to Address Health Disparities
Announcement Number: NOT-MD-20-025
Deadline: Varies
Purpose: The purpose of this Notice of Special Interest is to support investigative and collaborative research focused on developing and evaluating simulation modeling and systems science to understand and address minority health and health disparities.
Award: Varies
Eligibility & Guidelines: Here
Announcement Expires: May 08, 2023


Title: Innovative Research in Cancer Nanotechnology (IRCN) (R01 Research Project Grant)
Announcement Number: PAR-20-284
Deadline: Varies
Purpose: This Funding Opportunity Announcement (FOA) entitled “Innovative Research in Cancer Nanotechnology (IRCN)” encourages applications promoting transformative discoveries in cancer biology and/or oncology through the use of nanotechnology. Proposed projects should address major barriers in cancer biology and/or oncology using nanotechnology and should focus on mechanistic studies to expand the fundamental understanding of nanomaterial and/or nano-device interactions with biological systems. These studies are expected to be relevant to the delivery of nanoparticles and/or nano-devices to desired and intended cancer targets in vivo and/or characterization of detection and diagnostic devices and sensors in vitro. IRCN awards are expected to produce fundamental knowledge to aid future and more informed development of nanotechnology-based cancer interventions.
Award: Application budgets are limited to $450K in direct costs per year and need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: May 5, 2023


Title: Notice of Special Interest (NOSI) of NIDCR in Supporting Dental, Oral, and Craniofacial Research Using Bioinformatic, Computational, and Data Science Approaches
Announcement Number: NOT-DE-20-006
Deadline: Varies
Purpose: The volume, dimension, and complexity of biomedical and behavioral research data are expanding rapidly, requiring bioinformatic, computational, and data science approaches to manage and analyze the data, address new questions, and obtain deeper insight from the data. This Notice of Special Interest (NOSI) calls for research and research training projects that focus on dental, oral, and craniofacial biology and diseases using bioinformatic, computational, and data science approaches.
Eligibility & Guidelines: Here
Announcement Expires: August 08, 2023


Title: Enabling Technologies to Accelerate Development of Oral Biodevices (R21 Research Grant)
Announcement Number: PAR-20-232
Deadline: February 16, June 16, October 16
Purpose: This Funding Opportunity Announcement (FOA) invites exploratory/developmental applications that propose transformative engineering solutions to technical challenges associated with meaningful development, substantial optimization of existing technologies and clinical translation of intraoral biodevices. Proposed technologies are expected to advance development of oral biodevices to clinical use, including but not limited to: precision medicine-based detection, diagnosis and treatment of oral and overall health conditions, and measurement of patient functional status and clinical outcome assessment. Areas of interest in this FOA include engineering approaches that allow integration of electronic, physical, and biological systems essential to the development of functional biodevices that are safe and effective for detection, diagnosis and treatment of oral and systemic disease. Products of this research will be proof-of-concept prototype biodevices, dedicated biosensors and associated core technologies that enable development of safe and effective intra-oral biodevices intended for specific clinical applications. To streamline the development of oral biodevices that advance precision medicine-based approaches in clinical practice, this FOA encourages interdisciplinary collaborations across engineering, multifunctional sensors, pharmacology, chemistry, medicine, and dentistry, as well as between academia and industry.
Award: Direct costs are limited to $275,000 over a two-year project period, with no more than $200,000 in direct costs allowed in any single year.
Eligibility & Guidelines: Here
Announcement Expires: May 08, 2023


Title: Enabling Technologies to Accelerate Development of Oral Biodevices (R01 Research Grant)
Announcement Number: PAR-20-233
Deadline: February 5, June 5, October 5
Purpose: This Funding Opportunity Announcement (FOA) invites applications that propose transformative engineering solutions to technical challenges associated with new development, substantial optimization of existing technologies and clinical translation of intraoral biodevices. Proposed technologies are expected to advance development of oral biodevices for clinical use, including but not limited to: precision medicine-based detection, diagnosis and treatment of oral and overall health conditions, and measurement of patient functional status and clinical outcome assessment. Areas of interest in this FOA include engineering approaches that allow integration of electronic, physical, and biological systems into functional biodevices that are safe and effective for detection, diagnosis and treatment of oral and systemic disease. Products of this research will be functional biodevices and integrated approaches thoroughly characterized to demonstrate preclinical safety and effective performance in support of specific intended clinical applications. To streamline the development of oral biodevices that advance precision medicine-based approaches in clinical practice, this FOA encourages interdisciplinary collaborations across engineering, multifunctional sensors, pharmacology, chemistry, medicine, and dentistry, as well as between academia and industry.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: May 08, 2023


Title: Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Research Project Grant)
Announcement Number: PAR-20-131
Deadline: February 5, June 5, October 5
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for projects to expand, improve, or transform the utility of mammalian cancer and tumor models for translational research.
With this FOA, the NCI intends to encourage submission of projects devoted to demonstrating that mammalian models or their derivatives used for translational research are robust representations of human biology, are appropriate to test questions of clinical importance, and provide reliable information for patients’ benefit. These practical goals contrast with the goals of many mechanistic, NCI-supported R01 projects that use mammals, or develop and use mammalian cancer models, transplantation tumor models, or models derived from mammalian or human tissues or cells for hypothesis-testing, non-clinical research. Among many other possible endeavors, applicants in response to this FOA could propose demonstrations of how to overcome translational deficiencies of mammalian oncology models, define new uses of mammalian models or their genetics for unexplored translational challenges, advance standard practices for use of translational models, test approaches to validate and credential models, or challenge current practices for how models are used translationally.
Award: Application budgets are limited to $450,000 direct costs per year.
Eligibility & Guidelines: Here
Announcement Expires:  May 8, 2023


Title: Biomedical Data Repository (U24 Resource-Related Research Projects – Cooperative Agreements)
Announcement Number: PAR-20-089
Deadline: January 25, 2021; September 24, 2021; January 25, 2022; September 26, 2022; January 25, 2023
Purpose: This funding opportunity announcement is designed to support biomedical data repositories. Biomedical data repositories under this announcement should have the primary function to ingest, archive, preserve, manage, distribute, and make accessible the data related to a particular system or systems. Support for data curation must be limited to that which improves the efficiency and accessibility of data ingestion, management, and use and reuse by the user communities. Support for software and tool development must be limited to that which provides essential functions or significantly increases the efficiency of operation of the repository. Applications that have a significant focus on software and tool development are not appropriate for this activity.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires:  May 09, 2023


Title: National Cancer Institute Program Project Applications (P01 Research Program Projects)
Announcement Number: PAR-20-077
Deadline: January 25, May 25, September 25
Purpose: With this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) invites applications for investigator-initiated Program Project (P01) applications. The proposed Program may address any of the broad areas of cancer research, including (but not limited to) cancer biology, cancer prevention, cancer diagnosis, cancer treatment, and cancer control. Basic, translational, clinical, and/or population-based studies in all of these research areas are appropriate. Each application submitted in response to this FOA must consist of at least three research projects and an Administrative Core. The projects must share a common central theme, focus, and/or overall objective.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Eligibility & Guidelines: Here
Announcement Expires: May 8, 2023


Title: Improving oral health and reducing disparities in adolescents (R01)
Announcement Number: PAR-20-058
Deadline: February 5, June 5, October 5
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to stimulate research to improve the oral health of adolescents in the United States, and to reduce observed oral health disparities and inequities in this population. This FOA defines “adolescents” as those individuals between the ages of 10 and 19.
Award: Application budgets are not limited but need to reflect the actual needs of the proposed project. The maximum project period is 5 years.
Eligibility & Guidelines: Here
Announcement Expires:  January 8, 2023


Title: Improving oral health and reducing disparities in adolescents (R21)
Announcement Number: PAR-20-059
Deadline: February 16, June 16, October 16
Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to encourage exploratory or developmental research to improve the oral health of adolescents in the United States, and to reduce observed oral health disparities and inequities in this population. This FOA defines “adolescents” as those individuals between the ages of 10 and 19.
Award: The combined budget for direct costs for the two year project period may not exceed $275,000. No more than $200,000 direct costs may be requested in any single year.
Eligibility & Guidelines: Here
Announcement Expires:  January 8, 2023


Title: NIDCR Small Grant Program for New Investigators (R03 Small Grant Program)
Announcement Number: PAR-21-084
Deadline: February 16, June 16, October 16
Purpose: This NIDCR Small Grant Program for New Investigators supports basic and clinical research conducted by scientists who are in the early stages of establishing an independent research career in oral, dental and craniofacial research. This R03 program supports pilot or feasibility studies and developmental research projects with the intention of obtaining sufficient preliminary data for a subsequent investigator¬ initiated Research Project Grant (R01) or equivalent application.
Award: A budget for direct costs of up to $200,000 may be requested. Application budgets should not exceed $100,000 in direct costs in either year.
Eligibility & Guidelines: Here
Announcement Expires:  January 8, 2024


Training (K Announcements)

Title: Mentored Research Scientist Development Award (K01 Training Grant)
Announcement Number: PA-20-190
Deadline: February 12, June 12, October 12
Purpose: The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide support and “protected time” (three to five years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence. Although all of the participating NIH Institutes and Centers (ICs) use this support mechanism to support career development experiences that lead to research independence, some ICs use the K01 award for individuals who propose to train in a new field or for individuals who have had a hiatus in their research career because of illness or pressing family circumstances..
This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor. Applicants proposing a clinical trial or an ancillary clinical trial as lead investigator, should apply to the companion FOA.
Award: Award budgets are composed of salary and other program-related expenses.
Eligibility & Guidelines: Here
Announcement Expires: May 8, 2023


Title: Mentored Quantitative Research Development Award (K25 Training Grant)
Announcement Number: PA-20-199
Deadline: March 12, July 12, November 12
Purpose: The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease. The K25 award will provide support and “protected time” for a period of supervised study and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research.
This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor. Applicants proposing a clinical trial or an ancillary clinical trial as lead investigator should apply to the companion FOA (PA-20-197).
Award: Award budgets are composed of salary and other program-related expenses.
Eligibility & Guidelines: Here
Announcement Expires: May 8, 2023


Title: NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00 Individual Predoctoral to Postdoctoral Transition Award)
Announcement Number: PAR-20-069
Deadline: February 12, June 12, October 12
Purpose: The purpose of the NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00) is to support outstanding graduate students from diverse backgrounds, including those from groups underrepresented in biomedical, clinical, behavioral and social sciences, over the transition from predoctoral to postdoctoral research training.. This phased award program will facilitate completion of graduate PhD or dual degree clinician scientist programs (F99) and progression to mentored postdoctoral positions in dental, oral and craniofacial research (K00). It is anticipated that successful completion of this phased award program will enable achievement of an independent research faculty position and subsequent NIDCR career development and research project awards. This Funding Opportunity Announcement (FOA) does not allow prospective fellows to propose to lead an independent clinical trial, but does allow prospective fellows to propose research experience in a clinical trial led by a sponsor or co-sponsor.
Award: For the F99 phase, award budgets are composed of stipends, tuition and fees, and institutional allowance, as described below.
For the K00 phase, award budgets are composed of salaries and fringe benefits, research and career development support, and indirect costs, as described below.
Eligibility & Guidelines: Here
Announcement Expires: January 8, 2023


Title: NIDCR Small Grant Program for New Investigators (R03 Small Grant Program)
Announcement Number: PAR-21-084
Deadline: February 16, June 16, October 16
Purpose: This NIDCR Small Grant Program for New Investigators supports basic and clinical research conducted by scientists who are in the early stages of establishing an independent research career in oral, dental and craniofacial research. This R03 program supports pilot or feasibility studies and developmental research projects with the intention of obtaining sufficient preliminary data for a subsequent investigator¬ initiated Research Project Grant (R01) or equivalent application.
Award: A budget for direct costs of up to $200,000 may be requested. Application budgets should not exceed $100,000 in direct costs in either year.
Eligibility & Guidelines: Here
Announcement Expires:  January 8, 2024


Title: NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00 Pre-doc to Post-doc Transition Award/Post-doctoral Transition Award)
Announcement Number: PAR-21-060
Deadline: February 12, June 12, October 12
Purpose: The purpose of the NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00) is to support outstanding graduate students from diverse backgrounds, including those from groups underrepresented in biomedical, clinical, behavioral and social sciences, over the transition from predoctoral to postdoctoral research training. This phased award program will facilitate completion of graduate PhD or dual degree clinician scientist programs (F99) and progression to mentored postdoctoral positions in dental, oral and craniofacial research (K00). It is anticipated that successful completion of this phased award program will enable achievement of an independent research faculty position and subsequent NIDCR career development and research project awards. This Funding Opportunity Announcement (FOA) does not allow applicants to propose to lead an independent clinical trial, but does allow applicants to propose research experience in a clinical trial led by a sponsor or co-sponsor.
Award: For the F99 phase, award budgets are composed of stipends, tuition and fees, and institutional allowance, as described below. For the K00 phase, award budgets are composed of salaries and fringe benefits, research and career development support, and indirect costs, as described below.
Eligibility & Guidelines: Here
Announcement Expires:  January 8, 2024


Title: NIDCR Dual Degree Dentist Scientist Predoctoral to Postdoctoral Transition Award (F99/K00 Pre-doc to Post-doc Transition Award/Post-doctoral Transition Award)
Announcement Number: PAR-21-108
Deadline: February 12, June 12, October 12
Purpose: The purpose of the NIDCR Dual Degree Dentist Scientist Predoctoral to Postdoctoral Transition Award (F99/K00) is to provide support and mentorship to outstanding students enrolled in integrated dual degree dental (DDS/DMD) and PhD programs during the transition from predoctoral student to postdoctoral scholar. This phased award program will facilitate completion of predoctoral dual degree dentist scientist training (F99) and progression to mentored postdoctoral positions in dental, oral and craniofacial research (K00). It is anticipated that successful completion of this phased award program will enhance dual degree dentist scientists’ research career trajectories. This Funding Opportunity Announcement (FOA) does not allow applicants to propose to lead an independent clinical trial, but does allow applicants to propose research experience in a clinical trial led by a sponsor or co-sponsor.
Award: For the F99 phase, award budgets are composed of stipends, tuition and fees, and institutional allowance, as described below. For the K00 phase, award budgets are composed of salaries and fringe benefits, research and career development support, and indirect costs, as described below.
Eligibility & Guidelines: Here
Announcement Expires:  January 8, 2024