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CReM Bank

The CReM maintains a state-of-the-art bank of frozen iPSC lines that have been derived by the CReM investigators. The ‘stem cell cassette’ lentiviral vector (STEMCCA), engineered at Boston University, was employed to derive many of the mouse and human iPSC lines housed in our bank. Many of these lines feature ‘knock-in’ genes that allow sophisticated tracking and purification of progenitors or more mature tissue-specific differentiated cells that can be derived in culture from the undifferentiated iPSCs. The CReM iPSC Core maintains frozen aliquots of our iPSC lines and makes these lines readily available to all Boston University and external investigators. In addition, ‘standard operating procedures’ (SOPs) are maintained and made available to CReM investigators allowing them to document how each cell line has been derived.
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HUMAN iPSCs AVAILABLE
iPSC Type/Disease Name/Designation Description iPSC Reprogramming Method Starting Materials Karyotype Immunofluorescence Staining for Pluripotency Markers Reference
Normal BMC1Normal Control (HFF)EF1a-hSTEMCCA4 loxp lentiviral infectionForeskin Fibroblasts46XYYesKotton lab
NormalBU1Normal Control hiPSC (pre cre excision)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XYYesMostoslavsky lab
NormalbBU1Normal Control hiPSCEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCs46XYYesMostoslavsky lab
NormalBU1Cr3-1BU1 Cre excisedEF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XYYesMostoslavsky lab
NormalBU2-15-Cr10Normal Control hiPSCEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCs46XYYesMostoslavsky lab
NormalBU3-10-Cr2Normal Control hiPSCEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCs46XYYesKurmann A. Cell Stem Cell 2015
NormalBU7-2-Cr8Normal Control hiPSCEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCs46XXNDMostoslavsky lab
NormalBU7-1SNormal Control hiPSCSendai virus-based infectionPBMCsNDNDMostoslavsky lab
NormalHR I 2hIPSC control- father of Long QT3 family (pre cre excision)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XYYesTerrenoire. J. Gen. Physiol. 2012. Vol. 141 No. 1 61–72
NormalHR I 2Cr2RhIPSC control- father of Long QT3 family (post cre excision)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XYYesTerrenoire. J. Gen. Physiol. 2012. Vol. 141 No. 1 61–72
NormalHR I 7AhIPSC control- father of Long QT3 family (pre cre excision)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XYYesTerrenoire. J. Gen. Physiol. 2012. Vol. 141 No. 1 61–72
NormalHR I 15hIPSC control- father of Long QT3 family (pre cre excision)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XYYesTerrenoire. J. Gen. Physiol. 2012. Vol. 141 No. 1 61–72
Alpha-1 PiZZRC2 100-3apha-1 antitrypsin deficiency, genotype PiZZEF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XXYesSomers A. Stem Cells 2011
Alpha-1 PiZZRC2 101apha-1 antitrypsin deficiency, genotype PiZZEF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XXYesSomers A. Stem Cells 2011
Alpha-1 PiZZRC2 102apha-1 antitrypsin deficiency, genotype PiZZEF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XXYesSomers A. Stem Cells 2011
Alpha-1 PiZZRC2 103apha-1 antitrypsin deficiency, genotype PiZZEF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XXYesSomers A. Stem Cells 2011
Alpha-1 PiZZRC2 104apha-1 antitrypsin deficiency, genotype PiZZEF1a-hSTEMCCA4 loxp lentiviral infectionDermal FibroblastsNDYesSomers A. Stem Cells 2011
Alpha-1 PIM HeerlenPiZMh1Alpha-1 Antitrypsin Deficiency; Genotype PiM Heerlen; "null"EF1a-hSTEMCCA4 loxp lentiviral infectionNDNDKotton/Wilson Labs
Alpha-1 PiQO BoltonPiBB1Alpha-1 Antitrypsin Deficiency; Genotype BoltonEF1a-hSTEMCCA4 loxp lentiviral infection46XYYesKotton/Wilson Labs
Alpha-1 PiSZ1PiSZ1Alpha-1 Antitrypsin Deficiency; Genotype PiSZEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesKotton/Wilson Labs
Alpha-1 PiSZ2PiSZ2Alpha-1 Antitrypsin Deficiency; Genotype PiSZEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCs46XXYesKotton/Wilson Labs
Alpha-1 PiSZ3PiSZ3Alpha-1 Antitrypsin Deficiency; Genotype PiSZEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesKotton/Wilson Labs
Alpha-1 PiMZ1PiMZ1Alpha-1 Antitrypsin Deficiency; Genotype PiMZEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesKotton/Wilson Labs
Alpha-1 PiFZ1PiFZ1Alpha-1 Antitrypsin Deficiency; Genotype PiFZEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesKotton/Wilson Labs
Alpha-1 PiZZ1PiZZ1Alpha-1 Antitrypsin Deficiency: Genotype PiZZEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCs46XYYesKotton/Wilson Labs
Alpha-1 PiZZ2PiZZ2Alpha-1 Antitrypsin Deficiency: Genotype PiZZEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesKotton/Wilson Labs
Alpha-1 PiZZ3PiZZ3-1-Cr3Alpha-1 Antitrypsin Deficiency: Genotype PiZZEF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XYYesKotton/Wilson Labs
Cystic Fibrosis DF508RC2 200hiPSC DF508 CFTR homozygous (CYSTIC FIBROSIS)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal FibroblastsNDYesSomers A. Stem Cells 2011
Cystic Fibrosis DF508RC2 201hiPSC DF508 CFTR homozygous (CYSTIC FIBROSIS)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal FibroblastsNDYesSomers A. Stem Cells 2011
Cystic Fibrosis DF508RC2 202hiPSC DF508 CFTR homozygous (CYSTIC FIBROSIS)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XYYesSomers A. Stem Cells 2011
Cystic Fibrosis DF508RC 204hiPSC DF508 CFTR homozygous (CYSTIC FIBROSIS)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XYYesSomers A. Stem Cells 2011
BMPR2 hetHPAH1hiPSC from patient with Primary pulmonary hypertension (BMPR2 het mutant exon 12; 2504delCEF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XXYesWest, J. Am J Physiol Cell Physiol 307: C415–C430, 2014.
SclerodermaSCL1hIPSC SCLERODERMA; Pt1EF1a-hSTEMCCA4 loxp lentiviral infectionDermal FibroblastsNDYesSomers A. Stem Cells 2011
K channel polymorphismsHR II 3Cr5hIPSC control- mother of Long QT3 family; benign K channel polymorphism KCNH2 K897TEF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XXYesTerrenoire. J. Gen. Physiol. 2012. Vol. 141 No. 1 61–72
K channel polymorphismsHR II 5AhIPSC control- mother of Long QT3 family; benign K channel polymorphism KCNH2 K897T (pe-excision)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XXYesTerrenoire. J. Gen. Physiol. 2012. Vol. 141 No. 1 61–72
K channel polymorphismsHR II 9AhIPSC control- mother of Long QT3 family; benign K channel polymorphism KCNH2 K897T (pre-excision)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XXYesTerrenoire. J. Gen. Physiol. 2012. Vol. 141 No. 1 61–72
Long QT3 SyndromeOA6 9Cr8hIPSC Long QT3 syndrome (Na channel SCN5A F1473C; and K polymorphism)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XYYesTerrenoire. J. Gen. Physiol. 2012. Vol. 141 No. 1 61–72
Long QT3 SyndromeOA6 17Cr8hIPSC Long QT3 syndrome (Na channel SCN5A F1473C; and K polymorphism)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XYYesTerrenoire. J. Gen. Physiol. 2012. Vol. 141 No. 1 61–72
Long QT3 SyndromeOA6 22Cr8hIPSC Long QT3 syndrome (Na channel SCN5A F1473C; and K polymorphism)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XYYesTerrenoire. J. Gen. Physiol. 2012. Vol. 141 No. 1 61–72
ChILD-NKX2.1 hetT1 1Cr NKX2.1 Pt 1hiPSC ChILD NKX2.1 het (Brain-Lung-Thyroid Syndrome), Pt 1 c.384_391del8 (GCCGTACC)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XXYesKurmann A. Cell Stem Cell 2015
ChILD-NKX2.1 hetT3 2Cr NKX2.1 Pt 3hiPSC ChILD NKX2.1 het deletion (Brain-Lung-Thyroid Syndrome); Pt3 large deletionEF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XXYesKurmann A. Cell Stem Cell 2015
ChILD-NKX2.1 hetT4 32Cr NKX2.1 Pt 4hiPSC ChILD NKX2.1 mutant (Brain-Lung-Thyroid Syndrome), Pt 4 c.552_556del5 (CCCGC)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XYYesKurmann A. Cell Stem Cell 2015
Sickle Cell SSSS-002-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-002-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-002-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-004-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-004-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-004-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-005-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-005-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-005-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-006-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-006-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-006-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-008-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-008-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-008-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-009-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-009-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-009-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-012-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-012-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-012-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-013-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-013-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-013-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-014-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-014-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-014-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-015-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-015-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-015-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-016-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-016-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-016-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-018-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-018-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-018-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-019-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-019-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-019-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-024-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-024-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-024-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-025-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-025-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-025-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-028-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-028-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-028-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-029-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-029-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-029-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-032-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-032-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-035-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-035-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-035-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-036-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-036-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-036-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-037-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-038-1Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-038-2Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab
Sickle Cell SSSS-038-3Sikle Cell DiseaseEF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMurphy/Mostoslavsky lab

 

 

HUMAN iPSCs UNAVAILABLE
iPSC Type/Disease Name/Designation Description iPSC Reprogramming Method Starting Materials Karyotype Immunofluorescence Staining for Pluripotency Markers Reference
ChILD-SPCSPC2-18hiPSC ChILD SPC I73T mutant (pre cre excision)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal FibroblastsNDNDKotton lab
Alpha-1 PiZZRC2 100-2apha-1 antitrypsin deficiency, genotype PiZZEF1a-hSTEMCCA4 loxp lentiviral infectionDermal FibroblastsNDYesSomers A. Stem Cells 2011
Alpha-1 PiZZRC2 100-7apha-1 antitrypsin deficiency, genotype PiZZEF1a-hSTEMCCA4 loxp lentiviral infectionDermal FibroblastsNDYesSomers A. Stem Cells 2011
Alpha-1 PiZZRC2 100-13apha-1 antitrypsin deficiency, genotype PiZZEF1a-hSTEMCCA4 loxp lentiviral infectionDermal FibroblastsNDYesSomers A. Stem Cells 2011
Cystic Fibrosis DF508RC2 203hiPSC DF508 CFTR homozygous (CYSTIC FIBROSIS)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal FibroblastsNDYesSomers A. Stem Cells 2011
SclerodermaSCL2hIPSC SCLERODERMA; Pt1EF1a-hSTEMCCA4 loxp lentiviral infectionDermal FibroblastsNDYesSomers A. Stem Cells 2011
SclerodermaSCL3hIPSC SCLERODERMA; Pt1EF1a-hSTEMCCA4 loxp lentiviral infectionDermal FibroblastsNDYesSomers A. Stem Cells 2011
ChILD-SPCS1 2Cr SPChiPSC ChILD SPC mutantEF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XXYesKotton lab
ChILD-SPBSP 212 1Cr3 SPBhiPSC ChILD SPB deficient ,121ins2, Pt 2-0212EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XXYesKotton lab
ChILD-ABCA3ABCA3 (SP300)hiPSC ChILD ABCA3 deficient, homo E609K, Pt 2-0300EF1a-hSTEMCCA4 loxp lentiviral infectionDermal FibroblastsNDYesKotton lab
ALSALS1AMYOTROPHIC LATERAL SCLEROSIS 1, TDP43 mutationEF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblast Corriell #ND32947NDYesMurphy Lab
Amyloidosis TTRTTR1TRANSTHYRETIN; TTR amyloidosis, L55P mutationEF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblast Corriell #GM0199846XXYesMurphy Lab
Giant platelet syndromeGM10461GIANT PLATELET SYNDROMEEF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblast Corriell #GM10461NDYesMurphy Lab
HemochromatosisHC1-1hemochromatosis (H63D/V256I)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XYYesMostoslavsky lab
HemochromatosisHC2-1hemochromatosis (C282Y)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XXYesMostoslavsky lab
HemochromatosisHC3-1hemochromatosis (C282Y)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts46XXYesMostoslavsky lab
FAPFAP6965-1Familial adenomatous polyposis; FAP (P1542X)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts (Coriell# GM06965)46XXYesMostoslavsky lab
FAPFAP3948-1Familial adenomatous polyposis; FAP (Q541X)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts (Coriell# GM03948)46XXYesMostoslavsky lab
FAPFAP3954-1Familial adenomatous polyposis; FAP (Q541X)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts (Coriell# GM06965)46XYYesMostoslavsky lab
FAPFAP6888-1Familial adenomatous polyposis; FAP (P1542X)EF1a-hSTEMCCA4 loxp lentiviral infectionDermal Fibroblasts (Coriell# GM03948)46XYYesMostoslavsky lab
Beta ThalTHAL1-1b-thalassemia (Glu26Lys)EF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMostoslavsky lab
Beta ThalTHAL2-1b-thalassemia (Glun39Term)EF1a-hSTEMCCA4 loxp lentiviral infectionPBMCsNDYesMostoslavsky lab

 

 

MOUSE iPSCs AVAILABLE
iPSC type Name/Designation Description iPSC Reprogramming Method Starting Materials Karyotype Immunofluorescence Staining for Pluripotency Markers Reference
Sox2-GFPST8 (Sox2-GFP)iPSC with Sox2-GFP knock-inTet-mSTEMCCATail Tip Fibroblasts40XYYesSommer CA et al. Stem Cells 2009.
Sox2-GFPST5 (Sox2-GFP)iPSC with Sox2-GFP knock-inTet-mSTEMCCATail Tip Fibroblasts40XYYesSommer CA et al. Stem Cells 2009.
Sox2-GFPSEFLBiPSC with Sox2-GFP knock-inEF1a-mSTEMCCA-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFLCiPSC with Sox2-GFP knock-inEF1a-mSTEMCCA-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFLDiPSC with Sox2-GFP knock-inEF1a-mSTEMCCA-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFLEiPSC with Sox2-GFP knock-inEF1a-mSTEMCCA-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFLFiPSC with Sox2-GFP knock-inEF1a-mSTEMCCA-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFCL5iPSC with Sox2-GFP knock-inEF1a-mSTEMCCA-RedLight-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFCL6iPSC with Sox2-GFP knock-inEF1a-mSTEMCCA-RedLight-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFCL10iPSC with Sox2-GFP knock-inEF1a-mSTEMCCA-RedLight-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFCL11iPSC with Sox2-GFP knock-inEF1a-mSTEMCCA-RedLight-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFCL15iPSC with Sox2-GFP knock-inEF1a-mSTEMCCA-RedLight-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFLB CreSEFLB Cre excisedEF1a-mSTEMCCA-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFLC CreSEFLC Cre excisedEF1a-mSTEMCCA-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFLD CreSEFLD Cre excisedEF1a-mSTEMCCA-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFLE CreSEFLE Cre excisedEF1a-mSTEMCCA-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFLF CreSEFLF Cre excisedEF1a-mSTEMCCA-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFCL5 CreSEFCL5 Cre excisedEF1a-mSTEMCCA-RedLight-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFCL6 Cre SEFCL6 Cre excisedEF1a-mSTEMCCA-RedLight-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFCL10 CreSEFCL10 Cre excisedEF1a-mSTEMCCA-RedLight-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFCL11 CreSEFCL11 Cre excisedEF1a-mSTEMCCA-RedLight-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab
Sox2-GFPSEFCL15 CreSEFCL15 Cre excisedEF1a-mSTEMCCA-RedLight-LoxpTail Tip Fibroblasts40XYYesMostoslavsky lab

 

 

MOUSE iPSCs UNAVAILABLE
iPSC type Name/Designation Description iPSC Reprogramming Method Starting Materials Karyotype Immunofluorescence Staining for Pluripotency Markers Reference
Nkx2.1-GFPNkx2.1GFPiPSC with Nkx2.1 GFP knockinEF1a-mSTEMCCA-LoxpTail Tip FibroblastsNDNoKotton Lab
Tie2-GFPTie2-GFPiPSC Tie2-GFP transgenicEF1a-mSTEMCCA-LoxpTail Tip FibroblastsNDNoKotton lab
SPC-GFPSPC-GFPiPSC SPC-GFP transgenicEF1a-mSTEMCCA-LoxpNDNoKotton lab
Nkx2.1-CreNkx2.1-CrexRosaiPSC with Nkx2.1 floxed lacZ lineage tag (pre-excision)EF1a-mSTEMCCA-Loxplung mesenchyme)NDNoKotton lab
T1a-GFPT1a-GFPiPSC with T1a-GFP transgenicEF1a-mSTEMCCA-LoxpTail Tip FibroblastsNDNoKotton lab
CFTR KOCFTR KOiPSC from CFTR/CFTR null mouseEF1a-mSTEMCCA-LoxpTail Tip FibroblastsNDNoKotton lab
Oct4-GFPOct4-GFPiPSC with Oct4-GFP knockinEF1a-mSTEMCCA-LoxpTail Tip FibroblastsNDNoKotton lab