People
Affiliated Faculty
Elise F. Morgan Ph.D.
Assistant Professor, Biomedical Engineering
Assistant Professor, Aerospace and Mechanical Engineering
Primary appointment, ME
Orthopaedic & Developmental Biomechanics Lab
M.S., Ph.D. Mechanical Engineering, UC Berkeley
B.S. Mechanical Engineering, Stanford University
CV: Link to Curriculum Vitae (pdf)
phone: (617) 353-2791
fax: (617) 353-5866
email: efmorgan@bu.edu
website:people.bu.edu/efmorgan/
office: PHO 532
office hours: By Appointment
Research Interests
- mechanical behavior of biological materials
- mechanical stimulation of tissue differentiation
- micromechanics of multiscale media
- damage mechanics
Professor Elise Morgan’s research focuses on the interplay between the mechanical behavior, structure, and biological function of tissues. She uses methods from engineering mechanics, materials science, and cell and molecular biology to investigate how mechanical “signals” (forces and displacements) contribute to the development, adaptation, degeneration, and regeneration of bone and cartilage. This work involves experimentation, computational modeling, and theoretical analysis. Through her research, Professor Morgan hopes to gain insight into causes and potential treatments for diseases or conditions such as osteoporosis, osteoarthritis, and impaired bone healing.
Current Research
Professor Morgan’s current research projects are in the characterization of in vivo loading conditions in bones, the effects of mechanical stimulation on joint and articular cartilage development, and the age-related biomechanical consequences of damage in bone.
Selected Recent Publications
Salisbury Palomares, KT, Gleason, RE, Mason, ZD, Cullinane, DM, Einhorn, TA, Gerstenfeld, LC, Morgan, EF "Mechanical Stimulation Alters Tissue Differentiation and Molecular Expression During Bone Healing" Journal of Orthopaedic Research (In Press)
Morgan, EF, Chien, KB, Mason, ZD, Pfeiffer, AJ, Barnes, GL, Einhorn, TA, Gerstenfeld, LC "Computed Tomography Assessment of Fracture Healing: Relationships Among Callus Structure, Composition, and Mechanical Function" Bone (In Press)
Morgan, EF, Mason, ZD, Bishop, G, Davis, AD, Gerstenfeld, LC, Einhorn, TA "Combined Effects of Recombinant Human BMP-7 (rhBMP-7) and Parathyroid Hormone (1-34) in Metaphyseal Bone Healing" Bone (In Press)
Leong, PL and Morgan, EF "Measurement of Fracture Callus Material Properties via Nanoindentation" Acta Biomaterialia 4 (5): 1569-75 (2008)
Kaufman, JD, Miller, GE, Morgan, EF, Klapperich, CM "Time-Dependent Mechanical Characterization of Poly(2-hydroxyethyl methacrylate) Hydrogels Using Nanoindentation and Confined Compression" Journal of Materials Research 23 (5): 1472-1481 (2008)
Liu, L and Morgan, EF "Accuracy and Precision of Digital Volume Correlation in Quantifying Displacements and Strains in Trabecular Bone" Journal of Biomechanics
40 (15): 3516-20 (2007)
