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| There are 16 research laboratories in the Department of Anatomy & Neurobiology. They are listed below, with a brief
description of each area of research. Click on the name of each lab to go to the pages that will provide details about research activities,
the members of the lab, methodology, publications, and contact information. |
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Laboratory of Autism Neuroscience Research  |
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| The members of this laboratory study the structure of the brain in autism, and
the effects of this condition on the distribution and function of receptors for neurotransmitters. |
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| Laboratory of Brain Imaging |
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| This laboratory uses high field MRI to investigate cortical plasticity, face representation
in the cortex, and axonal connectivity. Members of the lab are also involved in the development of new MRI
applications, and the verification of existing techniques using single unit recording and optical imaging. |
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| Laboratory of Cardiovascular Biology |
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| Dr. Hoagland's lab investigates the regulation of venous blood pressure and fluid volume,
and how these factors contribute to hypertension. |
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| Laboratory of Cerebral Dynamics |
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| This laboratory studies the ability of the brain to undergo structural and
functional reorganization following early brain damage. In addition to anatomical and
behavioral assessments, the organization of the brain is also studied using temporary
deactivation provided by cooling or transcranial magnetic stimulation. |
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| Laboratory of Cellular Biology of the Basal Ganglia and Motor Disorders |
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| This laboratory investigates the anatomical and functional organization of the
basal ganglia in the normal brain and in animal models of Parkinson's disease, with a particular
interest in dyskinesia and GABA-mediated signaling. |
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| Laboratory of Cognitive Neurobiology |
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| The Laboratory of Cognitive Neurobiology is broadly interested in the neurobiological
basis of learning and memory in the primate. The role of the limbic system and prefrontal cortex are
of particular interest, especially the changes with hypertension and/or advancing age. |
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| Laboratory of Developmental Cognitive
Neuroscience |
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| Dr. Tager-Flusberg's laboratory has a long standing interest in the language and social-cognitive
impairments in autism, and studies autistic individuals using both behavioral and brain imaging methodologies.
Their studies also include children with other genetically based neurodevelopmental disorders, including specific
language impairment and Williams syndrome. |
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| Laboratory of Electron Microscopy |
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| Dr. Peters studies the ultrastructural changes that occur with normal aging in the
cells and neuropil of the cerebral hemispheres of Rhesus monkeys. |
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| Laboratory of In Vitro Neurophysiology |
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| Dr Luebke's laboratory is interested in the electrophysiological and morphological properties of neocortical
neurons in the rodent and primate prefrontal cortex across the lifespan. |
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| Laboratory of Systems Molecular Signaling and Chemical Biology |
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| The members of this laboratory use molecular biological techniques to investigate
the cellular basis of neurodegeneration, particularly in conditions in which genetic defects produce
proteins with abnormally long sequences of the amino acid glutamatine, such as Huntington's Disease. |
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| Laboratory of Neuropsychology |
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| A major focus of interest in the Laboratory of Neuropsychology is the impact of alcohol use on cognition and brain structure. |
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| Laboratory of Retinal Microcircuitry |
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| Dr. Zucker's laboratory focuses on the synaptic circuitry of the mammalian retina,
with a particular emphasis on the cholinergic amacrine cell. |
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| Laboratory of Sleep and Circadian Physiology |
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| Dr. Zhdanova's laboratory studies the physiology of sleep and circadian rhythms in primates and zebrafish. |
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| Laboratory of Stereology and Morphometry |
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| The focus of this laboratory is the effect of perinatal manipulation of dietary choline and folate
on the structure of the brain, particularly those regions involved in spatial memory. The lab specializes in the use
of stereological techniques to assess neuron number and volume. |
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| Laboratory of Visual Neuropathology |
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| Dr. Sandell's laboratory studies the anatomical remodeling in human retinas from patients with retinitis pigmentosa,
animal models of the disease, and the structural changes in the brain in aging monkeys. |
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| Laboratory of Visual Perception and Cognition |
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| The emphasis of this laboratory is on the physiology of information transmission in the normal
mammalian brain, studied using MRI techniques, electrophysiology, and optical imaging. |
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