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| Laboratory of Systems Molecular Signaling and Chemical Biology |
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| Laboratory of Systems Signaling |
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Below are listed some publications from the lab pertaining to the molecular signaling pathways involved in neurodegeneration, particularly those caused by expanded polyglutamine repeats.
 indicates a link to PubMed.
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Kumaraswamy A, Sanchez I. Screens for proteotoxicity-induced changes in the mitochondria proteome. J Neurosci. 2004 [Abstr] |
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Zacharin K, Lipovsky A, Sanchez I. Modulation of the calcium activated potassium channel subunit 3 (SK3) by expanded polyglutamine repeats and ER Stress. J Neurosci. 2004.[Abstr] |
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Sanchez I, Mahlke C,Yuan J. A Pivotal role for Oligomerization in Expanded Polyglutamine Neurodegenerative disorders. 2003. Nature 421: 373- 379. |
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Kang S-J, Sanchez I Niasen J, Yuan J. Dissociation between Neurodegeneration and caspase 11- mediated caspase 1 and caspase 3 activation. 2003. JNeurosc.23:5455-5460. |
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Sanchez I, Yuan J. A convoluted way to die. 2001. Neuron 29: 563-566. |
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Sanchez I, C-J Xu, Juo P, Kakisuka A, Blenis J, Yuan J. Caspase 8 is required for Polyglutamine-induced cell death. 1999. Neuron 22:623-633. |
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Sanchez I, Hassinger L, Sihag RK, D.W. Cleveland, P. Mohan, Nixon RA. Local Control of Neurofilament Accumulation during Radial Growth of Myelinating Axons In Vivo: Selective Role of a Site Specific Phosphorylation. 2000. J Cell Biol.151:1013-1024. |
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Sanchez I, Hassinger L, Paskevich PA, Nixon RA. Oligodendroglia regulate the regional expansion of axon caliber and local accumulation of neurofilaments during development independently of myelin formation. 1996. J.Neurosc.16:5095-5105. |
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