Jean-Jacques Soghomonian, Ph.D.
Cellular Biology of the Basal Ganglia and Motor Disorders

The lab publishes in various neuroscience journals on the functional organization of the basal ganglia. Recent publications have focused on studies of l-DOPA in experimental models of Parkinson's disease. For a complete list of publications please see the individual pages for the members of the lab.

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Laprade, N. and Soghomonian, J.-J., Differential regulation of mRNA levels encoding for the two isoforms of glutamate decarboxylase (GAD65 and GAD67) by dopamine receptors in the rat striatum. Mol. Brain Res., 34 (1995) 65-74.
Laprade, N., Radja, F., Reader, T. and Soghomonian, J.-J., Dopamine receptor agonists regulate levels of the serotonin 5-HT2A receptor and its mRNA in a subpopulation of striatal neurons, Journal of Neuroscience, 16 (1996) 3727-3736.
Soghomonian, J.-J. and Laprade, N., Glutamate decarboxylase (GAD67 and GAD65) gene expression is increased in a sub-population of neurons in the putamen of parkinsonian monkeys, Synapse, 27 (1997) 122-132.
Soghomonian, J.-J. and Martin, D.L., Two isoforms of glutamate decarboxylase: why? Trends in Pharmacological Sciences, 19 (1998) 500-505.
Nielsen, K.N. and Soghomonian, J.-J. Dual effects of intermittent or continuous L-DOPA administration on gene expression in the globus pallidus and subthalamic nucleus of adult rats with a unilateral 6-OHDA lesion. Synapse 49 (2003) 246-260.
Nielsen, K.N. and Soghomonian, J.-J. Normalization of glutamate decarboxylase gene expression in the entopeduncular nucleus of rats with a unilateral 6-OHDA lesion correlates with increased GABAergic input following intermittent but not continuous levodopa. Neuroscience, 123 (2004) 31-42.
Laboratory of Autism Neuroscience Research
Laboratory of Brain Imaging
Laboratory of Cardiovascular Biology
Laboratory of Cerebral Dynamics
Cellular Biology of the Basal Ganglia and Motor Disorders.
Laboratory of Cognitive Neurobiology
Laboratory of Developmental Cognititve Neuroscience
Laboratory of Electron Microscopy
Laboratory of In Vitro Neurophysiology
Laboratory of Systems Molecular Signaling and Chemical Biology
Laboratory of Neuropsychology
Laboratory of Retinal Microcircuitry
Laboratory of Sleep and Circadian Physiology
Laboratory of Stereology and Morphometry
Laboratory of Visual Neuropathology
Laboratory of Visual Perception and Cognition