Laboratory of Sleep and Circadian Physiology
Irina V. Zhdanova, MD, Ph.D.
Research Associate Professor
Phone: 617-638-8002
Fax: 617-638-4676
Email: zhdanova@bu.edu
Location: R - 911, BUSM
CV

Dr. Zhdanova received her MD in Internal Medicine from the 1st Leningrad Medical Institute and has specialized in Clinical Physiology. She then received her PhD in Physiology of Behavior from the Institute of Experimental Medicine (St. Petersburg Russia). She completed her post-doctoral training at the Institute of Physiology, Russian Academy of Sciences, and then at the Massachusetts Institute of Technology. Dr. Zhdanova is studying the role of endogenous factors secreted into the cerebrospinal fluid and/or blood circulation in sleep regulation. Among these factors, the hormone of the pineal gland, melatonin, and the glycoproteins secreted by the subcomissural organ are currently under investigation in her laboratory. To study the effects of these factors on sleep, cognitive performance and drug abuse and to elucidate the mechanisms involved, the experimental procedures are conducted in diverse species: humans, monkeys and zebrafish.

Dr. Zhdanova teaches in the Neuroscience course offered in the Medical School (AN703). She is a leader of the Carnegie Initiative group "Alternative Pathways in the Neurosciences".

Dr. Zhdanova is a member of the Department Qualifying Exam Committee and the Medical School Executive Committee of the Cell and Molecular Biology program.

Zhdanova IV (2004 ) Advances in the management of insomnia. Expert Opin Pharmacother. 5:1573-9.
Holmqvist B, Ellingsen B, Forsell J, Zhdanova I, Alm P. (2004 ) The early ontogeny of neuronal nitric oxide synthase systems in the zebrafish. J Exp Biol., 207(Pt 6):923-35.
Danilova N, Krupnik VE, Sugden D, Zhdanova IV. (2004 ) Melatonin stimulates cell proliferation in zebrafish embryo and accelerates its development. FASEB J. 18: 751-3.
Zhdanova IV, Giorgetti M. (2002 ) Melatonin alters behavior and cAMP levels in nucleus accumbens induced by cocaine treatment. Brain Res. 956: 323-31.
Zhdanova IV, Geiger DA, Schwagerl AL, Leclair OU, Taylor JA, Rosene DL, Moss MB, Madras BK (2002 ) Melatonin promotes sleep in three species of diurnal non-human primates. Physiol. Behav. 75:523-529
Zhdanova IV, S. Wang, O.U. Leclair, N. Danilova (2001) Melatonin promotes sleep-like behavior in zebrafish. Brain Research 903 (1-2): 263-268
Dr. Mark Moss
Terri Ach, MS.
Dr. Peter Bergethon
Dr. Marlene Oscar Berman
Dr. Gene Blatt
Dr. Todd Hoagland
Dr. Richard Hoyt
Dr. Robert Joseph
Dr. Thomas Kemper
Dr. Ronald Killiany
Dr. Dae-Shik Kim
Dr. Jennifer Luebke
Dr. Tara Moore
Dr. Kalidas Nandy
Dr. Deepak Pandya
Dr. Monica Pessina
Dr. Alan Peters
Dr. Daniela Plesa Skwerer
Dr. Itamar Ronen
Dr. Douglas Rosene
Dr. R. Jarrett Rushmore
Dr. Ivelisse Sanchez
Dr. Julie Sandell
Dr. Donald Siwek
Dr. Jean-Jacques Soghomonian
Dr. Helen Tager-Flusberg
Dr. Louis Toth
Dr. Antoni Valero-Cabre
Dr. Deborah Vaughan
Dr. Elizabeth Whitney
Dr. Irina Zhdanova
Dr. Charles Zucker