Dr. Luebke received her doctorate in Anatomy & Neurobiology from Boston University School of Medicine. She completed a first postdoctoral fellowship in neurophysiology at Harvard Medical School and a second postdoctoral fellowship in neurophysiology at Tufts University School of Medicine and joined the Departments of Psychiatry and of Anatomy & Neurobiology at BUSM in 1995. Dr. Luebke maintains a laboratory in which whole-cell patch-clamp and intracellular filling techniques are used to examine the electrophysiological and morphological properties of neurons in in vitro slices of monkey and rat neocortex. Research is focused on action potential firing patterns (and underlying ionic currents), glutamatergic and GABAergic synaptic response properties and detailed dendritic architecture. Data from single neurons are incorporated into computational models in collaboration with mathematicians at Mt. Sinai School of Medicine. In addition, collaborations are ongoing with investigators at BUSM who use molecular biological (single cell PCR and microarray) and electron microscopic (ultrastructural analysis) techniques to examine cells from which recordings are obtained. Overall goals include: 1) to examine the individual and network properties of cells in the prefrontal cortex and 2) to determine the effects of normal aging on these properties in the rhesus monkey. Dr. Luebke's research is funded by the NIH.

Dr. Luebke teaches laboratory sections and lectures in the Medical Neurosciences course and in the Medical Histology course offered in the Medical School. In addition, Dr. Luebke is involved in teaching graduate neuroscience courses at BUSM.

Dr. Luebke's current service commitments include service as an advisor in the Division of Graduate Medical Sciences Masters of Medical Science program and membership on the Dept. of Anatomy & Neurobiology's "Portfolio" and "Qualifying Examination" committees.