The BU CTSI has developed an organizational structure that creates a clear division of effort and lines of responsibility without building silos that impede communication and coordination. In addition, our lines of communication are bi-directional. Strategic goals and priorities come “down” from NCATS, the national CTSA network, and our BU CTSI Director. At the same time, ideas for program implementation and new initiatives are able to “flow up” from leaders, staff, and scholars.