September 6, 2018
Behaviors such as physical inactivity, smoking and unhealthy eating have an enormous negative influence on health. Although unhealthy behaviors can lead to chronic disease, healthy behavior changes can be part of successful disease treatments. But making lasting behavior change is difficult, so translational scientists seek to understand, develop and implement more efficient and effective behavioral interventions, just as they do for the development of drugs, devices and medical procedures. Latest Director’s Message >
New Test Enables Faster Diagnosis of Deadly Disease
NCATS’ small business support enabled the development and analysis of a simple paper test for diarrheal disease. The test does not need electricity and can detect seven common causes of diarrhea in less than 30 minutes. The platform technology used holds promise for diagnosing many different diseases. Learn more about the technology.
NCATS Develops New Technique to Look Inside 3-D Cells
NCATS scientists have created a simple, fast and automated process to make 3-D tissues transparent. The new method enables many types of observations within 3-D growth environments, such as locating molecules inside a cell or finding damaged DNA. Learn more about this technique, which could be used to test large numbers of drugs.
CTSA Program Support Enables Improved Melanoma Treatment
UCLA researchers, supported in part through NCATS’ Clinical and Translational Science Awards (CTSA) Program, discovered four subtypes of melanoma, the most serious form of skin cancer. They found that two types of cancer treatments led to melanoma cells becoming resistant to treatment. Read more about the research.
Using Robots and Stem Cells to Produce Organ Models
NIH-supported researchers have developed an automated procedure for reliably producing kidney organoids on a large scale and in a format that works with current drug discovery screening tools. Organoids are miniature versions of an organ that are grown in a laboratory and can mimic key features of a human organ’s structure and function. Learn more about this procedure.
Meet More NCATS Staff
Donald C. Lo, Ph.D., is the director of NCATS’ Therapeutic Development Branch within the Division of Pre-Clinical Innovation. LaKeshia D. Wood, M.P.A., is the ethics coordinator in the Office of Management Analysis and Ethics within the NCATS Office of Administrative Management. Learn more about these and other staff members via NCATS Staff Profiles >